BR112022005559A2 - Sistemas e métodos para melhorar a irm de baixa dose com contraste volumétrico intensificado - Google Patents

Sistemas e métodos para melhorar a irm de baixa dose com contraste volumétrico intensificado

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Publication number
BR112022005559A2
BR112022005559A2 BR112022005559A BR112022005559A BR112022005559A2 BR 112022005559 A2 BR112022005559 A2 BR 112022005559A2 BR 112022005559 A BR112022005559 A BR 112022005559A BR 112022005559 A BR112022005559 A BR 112022005559A BR 112022005559 A2 BR112022005559 A2 BR 112022005559A2
Authority
BR
Brazil
Prior art keywords
systems
methods
improve low
individual
dose
Prior art date
Application number
BR112022005559A
Other languages
English (en)
Inventor
Gong Enhao
Venkata Srivathsa Pasumarthi
Tamir Jonathan
Zhang Tao
Original Assignee
Subtle Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Subtle Medical Inc filed Critical Subtle Medical Inc
Priority claimed from PCT/US2020/052123 external-priority patent/WO2021061710A1/en
Publication of BR112022005559A2 publication Critical patent/BR112022005559A2/pt

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5608—Data processing and visualization specially adapted for MR, e.g. for feature analysis and pattern recognition on the basis of measured MR data, segmentation of measured MR data, edge contour detection on the basis of measured MR data, for enhancing measured MR data in terms of signal-to-noise ratio by means of noise filtering or apodization, for enhancing measured MR data in terms of resolution by means for deblurring, windowing, zero filling, or generation of gray-scaled images, colour-coded images or images displaying vectors instead of pixels
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G06T7/0014—Biomedical image inspection using an image reference approach
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T11/00—2D [Two Dimensional] image generation
    • G06T11/003—Reconstruction from projections, e.g. tomography
    • G06T11/005—Specific pre-processing for tomographic reconstruction, e.g. calibration, source positioning, rebinning, scatter correction, retrospective gating
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T11/00—2D [Two Dimensional] image generation
    • G06T11/003—Reconstruction from projections, e.g. tomography
    • G06T11/008—Specific post-processing after tomographic reconstruction, e.g. voxelisation, metal artifact correction
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T19/00—Manipulating 3D models or images for computer graphics
    • G06T19/20—Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T3/00—Geometric image transformations in the plane of the image
    • G06T3/60—Rotation of whole images or parts thereof
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00—Image enhancement or restoration
    • G06T5/50—Image enhancement or restoration using two or more images, e.g. averaging or subtraction
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00—Image enhancement or restoration
    • G06T5/60—Image enhancement or restoration using machine learning, e.g. neural networks
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00—Image enhancement or restoration
    • G06T5/90—Dynamic range modification of images or parts thereof
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/30—Determination of transform parameters for the alignment of images, i.e. image registration
    • G06T7/33—Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods
    • G06T7/337—Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods involving reference images or patches
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/60—Analysis of geometric attributes
    • G06T7/62—Analysis of geometric attributes of area, perimeter, diameter or volume
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10088—Magnetic resonance imaging [MRI]
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20084—Artificial neural networks [ANN]
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20212—Image combination
    • G06T2207/20216—Image averaging
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30016—Brain
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30096—Tumor; Lesion
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2219/00—Indexing scheme for manipulating 3D models or images for computer graphics
    • G06T2219/20—Indexing scheme for editing of 3D models
    • G06T2219/2016—Rotation, translation, scaling

Landscapes

  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Signal Processing (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Artificial Intelligence (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Quality & Reliability (AREA)
  • Architecture (AREA)
  • Computer Graphics (AREA)
  • Computer Hardware Design (AREA)
  • General Engineering & Computer Science (AREA)
  • Software Systems (AREA)
  • Geometry (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Image Processing (AREA)
  • Image Analysis (AREA)

Abstract

sistemas e métodos para melhorar a irm de baixa dose com contraste volumétrico intensificado. são fornecidos métodos e sistemas para melhorar a robustez e generalização do modelo. o método pode compreender: adquirir, usando um aparelho de imagem médica, uma imagem médica de um indivíduo; reformatar a imagem médica do indivíduo em múltiplas orientações de escaneamento; aplicar um modelo de rede profunda à imagem médica para melhorar a qualidade da imagem médica; e produzir uma imagem de melhor qualidade do indivíduo para análise por um médico.
BR112022005559A 2019-09-25 2020-09-23 Sistemas e métodos para melhorar a irm de baixa dose com contraste volumétrico intensificado BR112022005559A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962905689P 2019-09-25 2019-09-25
PCT/US2020/052123 WO2021061710A1 (en) 2019-09-25 2020-09-23 Systems and methods for improving low dose volumetric contrast-enhanced mri

Publications (1)

Publication Number Publication Date
BR112022005559A2 true BR112022005559A2 (pt) 2022-06-21

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022005559A BR112022005559A2 (pt) 2019-09-25 2020-09-23 Sistemas e métodos para melhorar a irm de baixa dose com contraste volumétrico intensificado

Country Status (9)

Country Link
US (2) US11624795B2 (pt)
EP (1) EP4035124A4 (pt)
JP (1) JP2022550688A (pt)
KR (1) KR20220067543A (pt)
CN (1) CN112470190A (pt)
AU (1) AU2020352531A1 (pt)
BR (1) BR112022005559A2 (pt)
CA (1) CA3151320A1 (pt)
IL (1) IL291551A (pt)

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US11727087B2 (en) * 2021-04-05 2023-08-15 Nano-X Ai Ltd. Identification of a contrast phase depicted in a medical image
CN113450296B (zh) * 2021-07-12 2022-09-06 首都医科大学附属北京天坛医院 一种医学图像生成方法、装置、电子设备及存储介质
WO2023055721A1 (en) * 2021-09-29 2023-04-06 Subtle Medical, Inc. Systems and methods for contrast dose reduction
EP4334900A1 (en) * 2021-10-15 2024-03-13 Bracco Imaging S.p.A. Training a machine learning model for simulating images at higher dose of contrast agent in medical imaging applications
KR20240019639A (ko) * 2022-08-04 2024-02-14 메디컬아이피 주식회사 비조영영상을 조영영상으로 변환하는 방법 및 그 장치
WO2024097700A1 (en) * 2022-11-02 2024-05-10 Subtle Medical, Inc. Systems and methods for adaptive deep learning mr image enhancement with property constrained unrolled network
WO2024107695A1 (en) * 2022-11-16 2024-05-23 Subtle Medical, Inc. Systems and methods for arbitrary level contrast dose simulation in mri
CN116071401B (zh) * 2023-01-28 2023-08-01 中日友好医院(中日友好临床医学研究所) 基于深度学习的虚拟ct图像的生成方法及装置
CN116612206B (zh) * 2023-07-19 2023-09-29 中国海洋大学 一种利用卷积神经网络减少ct扫描时间的方法及系统

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DE102006001681B4 (de) * 2006-01-12 2008-07-10 Wismüller, Axel, Dipl.-Phys. Dr.med. Verfahren und Vorrichtung zur Darstellung mehrkanaliger Bilddaten
US10289953B2 (en) * 2011-12-13 2019-05-14 Koninklijke Philips N.V. Dose optimization based on outcome quality
US9266891B2 (en) * 2012-11-16 2016-02-23 Boehringer Ingelheim International Gmbh Substituted [1,2,4]triazolo[4,3-A]pyrazines that are BRD4 inhibitors
US10070828B2 (en) * 2013-03-05 2018-09-11 Nview Medical Inc. Imaging systems and related apparatus and methods
US9384528B2 (en) * 2014-05-28 2016-07-05 EchoPixel, Inc. Image annotation using a haptic plane
DE102014203463B3 (de) * 2014-02-26 2015-07-09 Siemens Aktiengesellschaft Patientenabhängige Optimierung der Kontrastmittelmenge
WO2016033458A1 (en) * 2014-08-29 2016-03-03 The University Of North Carolina At Chapel Hill Restoring image quality of reduced radiotracer dose positron emission tomography (pet) images using combined pet and magnetic resonance (mr)
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US10685429B2 (en) * 2017-02-22 2020-06-16 Siemens Healthcare Gmbh Denoising medical images by learning sparse image representations with a deep unfolding approach
US10096109B1 (en) * 2017-03-31 2018-10-09 The Board Of Trustees Of The Leland Stanford Junior University Quality of medical images using multi-contrast and deep learning
AU2018346938B2 (en) * 2017-10-09 2024-04-04 The Board Of Trustees Of The Leland Stanford Junior University Contrast dose reduction for medical imaging using deep learning
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WO2021061710A1 (en) 2019-09-25 2021-04-01 Subtle Medical, Inc. Systems and methods for improving low dose volumetric contrast-enhanced mri

Also Published As

Publication number Publication date
IL291551A (en) 2022-05-01
CA3151320A1 (en) 2021-04-01
CN112470190A (zh) 2021-03-09
US11624795B2 (en) 2023-04-11
US20230296709A1 (en) 2023-09-21
EP4035124A1 (en) 2022-08-03
AU2020352531A1 (en) 2022-03-31
US20220334208A1 (en) 2022-10-20
KR20220067543A (ko) 2022-05-24
JP2022550688A (ja) 2022-12-05
EP4035124A4 (en) 2023-10-11

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