BR112022003242A2 - Composto, composição, e, métodos de formação de imagens, de síntese enantiosseletiva e de produção - Google Patents
Composto, composição, e, métodos de formação de imagens, de síntese enantiosseletiva e de produçãoInfo
- Publication number
- BR112022003242A2 BR112022003242A2 BR112022003242A BR112022003242A BR112022003242A2 BR 112022003242 A2 BR112022003242 A2 BR 112022003242A2 BR 112022003242 A BR112022003242 A BR 112022003242A BR 112022003242 A BR112022003242 A BR 112022003242A BR 112022003242 A2 BR112022003242 A2 BR 112022003242A2
- Authority
- BR
- Brazil
- Prior art keywords
- imaging
- compound
- composition
- production methods
- enantioselective synthesis
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003384 imaging method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000001308 synthesis method Methods 0.000 title abstract 2
- 239000002872 contrast media Substances 0.000 abstract 1
- 238000002595 magnetic resonance imaging Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Radiology & Medical Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Abstract
composto, composição, e, métodos de formação de imagens, de síntese enantiosseletiva e de produção. campo técnico da invenção. a invenção refere-se a isômeros de compostos de quelatos e seu uso como agentes de contraste em procedimentos de formação de imagens de ressonância magnética (irm).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962895121P | 2019-09-03 | 2019-09-03 | |
| PCT/EP2020/074645 WO2021043926A1 (en) | 2019-09-03 | 2020-09-03 | Manganese chelate isomers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022003242A2 true BR112022003242A2 (pt) | 2022-05-17 |
Family
ID=72356001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022003242A BR112022003242A2 (pt) | 2019-09-03 | 2020-09-03 | Composto, composição, e, métodos de formação de imagens, de síntese enantiosseletiva e de produção |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220315616A1 (pt) |
| EP (1) | EP4025259A1 (pt) |
| JP (1) | JP2022546554A (pt) |
| KR (1) | KR20220058574A (pt) |
| CN (1) | CN114423761A (pt) |
| AU (1) | AU2020340541A1 (pt) |
| BR (1) | BR112022003242A2 (pt) |
| CA (1) | CA3152191A1 (pt) |
| MX (1) | MX2022002586A (pt) |
| WO (1) | WO2021043926A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201610738D0 (en) | 2016-06-20 | 2016-08-03 | Ge Healthcare As | Chelate compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO331773B1 (no) | 2009-12-18 | 2012-03-26 | Ge Healthcare As | Mangankelater, sammensetninger omfattende slike og anvendelse av disse som kontrastmidler for magnettomografi (MR) |
| GB201610738D0 (en) | 2016-06-20 | 2016-08-03 | Ge Healthcare As | Chelate compounds |
| EP3687994B1 (en) * | 2018-08-06 | 2020-11-04 | Bracco Imaging SPA | Gadolinium bearing pcta-based contrast agents |
| CN114105983B (zh) * | 2021-11-09 | 2023-08-11 | 国科温州研究院(温州生物材料与工程研究所) | 手性1,4,7,10-四氮杂-2,6-吡啶环蕃衍生物及其金属螯合物的制备和应用 |
-
2020
- 2020-09-03 CN CN202080061544.2A patent/CN114423761A/zh active Pending
- 2020-09-03 CA CA3152191A patent/CA3152191A1/en active Pending
- 2020-09-03 US US17/640,259 patent/US20220315616A1/en active Pending
- 2020-09-03 BR BR112022003242A patent/BR112022003242A2/pt unknown
- 2020-09-03 EP EP20767545.5A patent/EP4025259A1/en active Pending
- 2020-09-03 KR KR1020227010586A patent/KR20220058574A/ko unknown
- 2020-09-03 JP JP2022514190A patent/JP2022546554A/ja active Pending
- 2020-09-03 AU AU2020340541A patent/AU2020340541A1/en active Pending
- 2020-09-03 MX MX2022002586A patent/MX2022002586A/es unknown
- 2020-09-03 WO PCT/EP2020/074645 patent/WO2021043926A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| CA3152191A1 (en) | 2021-03-11 |
| KR20220058574A (ko) | 2022-05-09 |
| MX2022002586A (es) | 2022-03-22 |
| AU2020340541A1 (en) | 2022-04-21 |
| CN114423761A (zh) | 2022-04-29 |
| EP4025259A1 (en) | 2022-07-13 |
| JP2022546554A (ja) | 2022-11-04 |
| US20220315616A1 (en) | 2022-10-06 |
| WO2021043926A1 (en) | 2021-03-11 |
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