BR112022001136A2 - Inibidor de fibrose do tecido em que polímero biocompatível é usado - Google Patents
Inibidor de fibrose do tecido em que polímero biocompatível é usadoInfo
- Publication number
- BR112022001136A2 BR112022001136A2 BR112022001136A BR112022001136A BR112022001136A2 BR 112022001136 A2 BR112022001136 A2 BR 112022001136A2 BR 112022001136 A BR112022001136 A BR 112022001136A BR 112022001136 A BR112022001136 A BR 112022001136A BR 112022001136 A2 BR112022001136 A2 BR 112022001136A2
- Authority
- BR
- Brazil
- Prior art keywords
- fibrosis
- tissue
- biocompatible polymer
- fibrosis inhibitor
- inhibitor
- Prior art date
Links
- 206010016654 Fibrosis Diseases 0.000 title abstract 9
- 230000004761 fibrosis Effects 0.000 title abstract 9
- 239000003112 inhibitor Substances 0.000 title abstract 4
- 229920000249 biocompatible polymer Polymers 0.000 title abstract 3
- 230000002401 inhibitory effect Effects 0.000 abstract 4
- 210000000056 organ Anatomy 0.000 abstract 2
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- Physiology (AREA)
Abstract
inibidor de fibrose do tecido em que polímero biocompatível é usado. a presente invenção refere-se a um problema para ser solucionado pela presente invenção é fornecer um inibidor de fibrose, que solucione o problema de inibir a fibrose de um órgão ou tecido da superfície, e especialmente de inibir a fibrose de uma superfície epicárdica. para esse fim, inibindo a fibrose, a presente invenção evita ou reduz o desenvolvimento subsequente de adesões, a fim de evitar danificar o órgão ou o tecido durante a re-operação. é fornecido um inibidor de fibrose para inibição de fibrose de um tecido, fixando um polímero biocompatível a um tecido em que é desejável inibir a fibrose.
Applications Claiming Priority (2)
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JP2019142482 | 2019-08-01 | ||
PCT/JP2020/029532 WO2021020576A1 (ja) | 2019-08-01 | 2020-07-31 | 生体適合性高分子を用いた組織の線維化抑制剤 |
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BR112022001136A2 true BR112022001136A2 (pt) | 2022-05-24 |
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BR112022001136A BR112022001136A2 (pt) | 2019-08-01 | 2020-07-31 | Inibidor de fibrose do tecido em que polímero biocompatível é usado |
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US (1) | US20220265896A1 (pt) |
EP (1) | EP4008368A4 (pt) |
JP (1) | JP7472142B2 (pt) |
KR (1) | KR20220044520A (pt) |
CN (1) | CN114144206B (pt) |
BR (1) | BR112022001136A2 (pt) |
CA (1) | CA3144487C (pt) |
TW (1) | TW202214312A (pt) |
WO (1) | WO2021020576A1 (pt) |
Family Cites Families (13)
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US5605938A (en) * | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
ATE244584T1 (de) | 1995-01-16 | 2003-07-15 | Baxter Int | Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen |
BR9911769B8 (pt) * | 1998-05-13 | 2021-06-22 | Innovata Ltd | composição para impedir ou reduzir a incidência de aderências pós-operatória em ou associadas com uma cavidade do corpo, kit de prevenção de adesão pós-operatória biocompatível, bioabsorvível e não tóxico e produtos ompreendendo a dita composição |
DE10025001A1 (de) | 2000-05-22 | 2001-11-29 | Aventis Behring Gmbh | Gewebekleber mit verbesserten anti-adhäsiven Eigenschaften |
AU771557B2 (en) | 1999-06-01 | 2004-03-25 | Vivolution A/S | Prevention of post surgical adhesions using a fibrin monomer sealant |
EP1494597A4 (en) * | 2002-04-01 | 2006-05-03 | Univ Texas | COMPOSITE MATERIAL FOR THE WOUND REPAIR |
JP4092397B2 (ja) | 2002-09-10 | 2008-05-28 | 国立循環器病センター総長 | 超高静水圧印加による移植用生体組織の処理方法 |
JP2008111530A (ja) | 2006-10-31 | 2008-05-15 | Sankei Giken:Kk | 管継手 |
JP2009050297A (ja) | 2007-08-23 | 2009-03-12 | Tokyo Medical & Dental Univ | 脱細胞処理液、脱細胞化組織の調製方法、移植片、及び培養部材 |
CN103405811B (zh) * | 2013-08-16 | 2015-10-28 | 陕西佰傲再生医学有限公司 | 一种防粘连生物膜及其制备方法 |
WO2016143746A1 (ja) * | 2015-03-12 | 2016-09-15 | 一般財団法人化学及血清療法研究所 | 脱細胞化組織を用いた癒着防止材及び代用生体膜 |
CN106310373B (zh) * | 2015-07-09 | 2019-06-18 | 陕西佰傲再生医学有限公司 | 一种生物修复膜及其制备方法 |
CN106983918B (zh) * | 2017-03-03 | 2020-05-05 | 北京博辉瑞进生物科技有限公司 | 一种生物防粘连材料、制备方法及其应用 |
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2020
- 2020-07-31 CN CN202080055061.1A patent/CN114144206B/zh active Active
- 2020-07-31 JP JP2021535469A patent/JP7472142B2/ja active Active
- 2020-07-31 EP EP20847207.6A patent/EP4008368A4/en active Pending
- 2020-07-31 BR BR112022001136A patent/BR112022001136A2/pt active Search and Examination
- 2020-07-31 CA CA3144487A patent/CA3144487C/en active Active
- 2020-07-31 KR KR1020227005549A patent/KR20220044520A/ko not_active Application Discontinuation
- 2020-07-31 WO PCT/JP2020/029532 patent/WO2021020576A1/ja unknown
- 2020-07-31 US US17/630,301 patent/US20220265896A1/en active Pending
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2021
- 2021-07-30 TW TW110128145A patent/TW202214312A/zh unknown
Also Published As
Publication number | Publication date |
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JP7472142B2 (ja) | 2024-04-22 |
EP4008368A1 (en) | 2022-06-08 |
WO2021020576A1 (ja) | 2021-02-04 |
CN114144206A (zh) | 2022-03-04 |
JPWO2021020576A1 (pt) | 2021-02-04 |
CA3144487C (en) | 2024-01-02 |
KR20220044520A (ko) | 2022-04-08 |
CA3144487A1 (en) | 2021-02-04 |
US20220265896A1 (en) | 2022-08-25 |
CN114144206B (zh) | 2023-03-24 |
EP4008368A4 (en) | 2023-06-07 |
TW202214312A (zh) | 2022-04-16 |
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