BR112021017288A2 - Dispositivos, sistemas e métodos para liberar agentes terapêuticos em uma parede do estômago - Google Patents
Dispositivos, sistemas e métodos para liberar agentes terapêuticos em uma parede do estômagoInfo
- Publication number
- BR112021017288A2 BR112021017288A2 BR112021017288A BR112021017288A BR112021017288A2 BR 112021017288 A2 BR112021017288 A2 BR 112021017288A2 BR 112021017288 A BR112021017288 A BR 112021017288A BR 112021017288 A BR112021017288 A BR 112021017288A BR 112021017288 A2 BR112021017288 A2 BR 112021017288A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- devices
- therapeutic agents
- drugs
- antrum
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 9
- 229940124597 therapeutic agent Drugs 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 210000002784 stomach Anatomy 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 abstract 5
- 238000002360 preparation method Methods 0.000 abstract 3
- 239000002775 capsule Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 2
- 230000008602 contraction Effects 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0116—Steering means as part of the catheter or advancing means; Markers for positioning self-propelled, e.g. autonomous robots
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/007—Injectors for solid bodies, e.g. suppositories
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3344—Measuring or controlling pressure at the body treatment site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3368—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8218—Gas operated
- A61M2205/8231—Gas operated using electrochemical gas generating device for the driving gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8275—Mechanical
- A61M2205/8281—Mechanical spring operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1042—Alimentary tract
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1042—Alimentary tract
- A61M2210/1053—Stomach
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/20—Blood composition characteristics
- A61M2230/208—Blood composition characteristics pH-value
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/60—Muscle strain, i.e. measured on the user
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Vascular Medicine (AREA)
- Robotics (AREA)
- Child & Adolescent Psychology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
dispositivos, sistemas e métodos para liberar agentes terapêuticos em uma parede do estômago. as modalidades da invenção proporcionam dispositivos engolíveis, preparações e métodos para a liberação de fármacos e outros agentes terapêuticos (at) dentro do trato gi e em particular a uma parede do antro (pa). as modalidades específicas fornecem um dispositivo engolível (de), tal como uma cápsula para a liberação de fármacos ou outros at para a pa. o de pode conter um componente ou montagem sensível à pressão que dispara a liberação e a inserção de uma preparação do agente terapêutico (pat) compreendendo pelo menos um at para a pa em resposta à pressão externa, como a pressão aplicada à cápsula secundária ou outro de por contrações do antro. as modalidades específicas do de podem ser moldadas para que se auto alinharem dentro de um antro para orientar adequadamente antes da injeção de pat na pa. as modalidades da invenção são particularmente úteis para liberar fármacos oralmente ou outros ats que são degradados dentro do trato gi e exigem injeção parenteral.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962812867P | 2019-03-01 | 2019-03-01 | |
US201962821250P | 2019-03-20 | 2019-03-20 | |
PCT/US2020/020540 WO2020180745A1 (en) | 2019-03-01 | 2020-02-28 | Devices, systems, and methods for delivering therapeutic agents into a stomach wall |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112021017288A2 true BR112021017288A2 (pt) | 2021-12-28 |
Family
ID=72236128
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112021017289A BR112021017289A2 (pt) | 2019-03-01 | 2020-02-28 | Distribuição propulsiva de fármacos a partir de um dispositivo engolível dentro do trato intestinal de um paciente |
BR112021017288A BR112021017288A2 (pt) | 2019-03-01 | 2020-02-28 | Dispositivos, sistemas e métodos para liberar agentes terapêuticos em uma parede do estômago |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112021017289A BR112021017289A2 (pt) | 2019-03-01 | 2020-02-28 | Distribuição propulsiva de fármacos a partir de um dispositivo engolível dentro do trato intestinal de um paciente |
Country Status (10)
Country | Link |
---|---|
US (4) | US11833319B2 (pt) |
EP (2) | EP3930688A4 (pt) |
JP (2) | JP2022523533A (pt) |
KR (2) | KR20220002275A (pt) |
CN (3) | CN113692275B (pt) |
AU (2) | AU2020233287A1 (pt) |
BR (2) | BR112021017289A2 (pt) |
CA (2) | CA3131781A1 (pt) |
MX (2) | MX2021010442A (pt) |
WO (2) | WO2020180746A1 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
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US9415004B2 (en) | 2010-12-23 | 2016-08-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8809269B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8734429B2 (en) | 2010-12-23 | 2014-05-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
US9259386B2 (en) | 2010-12-23 | 2016-02-16 | Rani Therapeutics, Llc | Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9402806B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
CN113692275B (zh) | 2019-03-01 | 2023-07-25 | 拉尼医疗有限公司 | 用于将治疗剂递送到胃壁中的装置、系统和方法 |
CN116897065A (zh) * | 2021-03-05 | 2023-10-17 | Bi生物技术有限公司 | 口服型物质传递装置 |
CN113576374B (zh) * | 2021-08-31 | 2022-08-30 | 武汉大学 | 一种板簧驱动的磁控施药胶囊机器人 |
CN113576373B (zh) * | 2021-08-31 | 2022-08-30 | 武汉大学 | 一种磁控微针穿刺施药胶囊 |
DK181266B1 (en) * | 2021-10-28 | 2023-06-14 | Biograil ApS | Drug delivery device with offset acutator mechanism |
WO2023148623A2 (en) * | 2022-02-01 | 2023-08-10 | Abhinav Goyal | Devices, insertion apparatus, and methods for administering samples |
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US8980822B2 (en) | 2010-12-23 | 2015-03-17 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8809269B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8764733B2 (en) | 2010-12-23 | 2014-07-01 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9284367B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
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US9259386B2 (en) | 2010-12-23 | 2016-02-16 | Rani Therapeutics, Llc | Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9861683B2 (en) | 2010-12-23 | 2018-01-09 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9402806B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
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CN113692275B (zh) | 2019-03-01 | 2023-07-25 | 拉尼医疗有限公司 | 用于将治疗剂递送到胃壁中的装置、系统和方法 |
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2020
- 2020-02-28 CN CN202080028728.9A patent/CN113692275B/zh active Active
- 2020-02-28 CN CN202080028786.1A patent/CN113692274A/zh active Pending
- 2020-02-28 AU AU2020233287A patent/AU2020233287A1/en active Pending
- 2020-02-28 CA CA3131781A patent/CA3131781A1/en active Pending
- 2020-02-28 EP EP20766653.8A patent/EP3930688A4/en active Pending
- 2020-02-28 JP JP2021550224A patent/JP2022523533A/ja active Pending
- 2020-02-28 US US16/805,583 patent/US11833319B2/en active Active
- 2020-02-28 CN CN202310832179.6A patent/CN116870341A/zh active Pending
- 2020-02-28 CA CA3131779A patent/CA3131779A1/en active Pending
- 2020-02-28 BR BR112021017289A patent/BR112021017289A2/pt unknown
- 2020-02-28 WO PCT/US2020/020544 patent/WO2020180746A1/en active Application Filing
- 2020-02-28 BR BR112021017288A patent/BR112021017288A2/pt unknown
- 2020-02-28 EP EP20765802.2A patent/EP3930693A4/en active Pending
- 2020-02-28 WO PCT/US2020/020540 patent/WO2020180745A1/en active Application Filing
- 2020-02-28 KR KR1020217030982A patent/KR20220002275A/ko unknown
- 2020-02-28 AU AU2020232610A patent/AU2020232610A1/en active Pending
- 2020-02-28 MX MX2021010442A patent/MX2021010442A/es unknown
- 2020-02-28 KR KR1020217030993A patent/KR20220002876A/ko unknown
- 2020-02-28 MX MX2021010450A patent/MX2021010450A/es unknown
- 2020-02-28 JP JP2021550223A patent/JP7465886B2/ja active Active
- 2020-02-28 US US16/805,317 patent/US11565095B2/en active Active
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2022
- 2022-12-27 US US18/089,478 patent/US20230137442A1/en active Pending
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2023
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JP2022523532A (ja) | 2022-04-25 |
CN113692275A (zh) | 2021-11-23 |
US20240139479A1 (en) | 2024-05-02 |
US20200276426A1 (en) | 2020-09-03 |
WO2020180745A1 (en) | 2020-09-10 |
BR112021017289A2 (pt) | 2021-12-28 |
EP3930688A4 (en) | 2022-11-30 |
EP3930688A1 (en) | 2022-01-05 |
MX2021010450A (es) | 2021-12-10 |
CN113692275B (zh) | 2023-07-25 |
AU2020232610A1 (en) | 2021-09-23 |
EP3930693A4 (en) | 2023-01-11 |
US20200276425A1 (en) | 2020-09-03 |
US20230137442A1 (en) | 2023-05-04 |
CN116870341A (zh) | 2023-10-13 |
US11565095B2 (en) | 2023-01-31 |
KR20220002275A (ko) | 2022-01-06 |
EP3930693A1 (en) | 2022-01-05 |
WO2020180746A1 (en) | 2020-09-10 |
MX2021010442A (es) | 2021-12-10 |
KR20220002876A (ko) | 2022-01-07 |
CA3131781A1 (en) | 2020-09-10 |
JP7465886B2 (ja) | 2024-04-11 |
CN113692274A (zh) | 2021-11-23 |
US11833319B2 (en) | 2023-12-05 |
AU2020233287A1 (en) | 2021-09-23 |
JP2022523533A (ja) | 2022-04-25 |
CA3131779A1 (en) | 2020-09-10 |
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