BR112021013416A2 - AUXILIARY DEVICE FOR INJECTION - Google Patents

Abstract

auxiliary device for injection. In one embodiment, an auxiliary device for driving injection is provided, including an upper side, a lower side, an opening in the lower side for receiving an automatic injector, and an elongated shaft extending between the upper side and the lower side. . the device further includes an elongated chamber having a first end and a second end and extending the length of the shaft and terminating at the opening, the chamber being configured to receive a portion of the automatic injection device and comprising a plurality of ribs that extend into the chamber for gripping the automatic injection device. the device may further include a notch in the opening for receiving a protrusion of the automatic injection device, when the automatic injection device is received into the chamber, wherein receiving the automatic injection device into the chamber and movement of the device auxiliary drive, toward the distal end of the automatic injection device, actuates the automatic injection device to deliver an injection.

Description

Descriptive Report of the Patent of Invention for "AUXILIARY DEVICE FOR INJECTION". background

[001] Rheumatoid arthritis (RA) is an autoimmune disease that attacks the tissues near the joints and other parts of the body, causing swelling and chronic pain. RA focuses on the synovial tissues within the joints. Autoimmune diseases occur when the body's immune system mistakes its own tissues for foreign tissue, and attacks the tissue through antibodies that hunt down and destroy the "invaders" in the synovium. Patients suffering from RA experience joint stiffness, which often starts in the fingers and toes, causing joint pain and restricting movement. These patients have difficulties in articulating the joints, and, consequently, manipulating devices with their hands becomes a difficult task. Most self-administered drugs require a drug delivery device, for example an automatic injector, and often these devices require manipulation of the device by the patient to administer a dose to himself. The automatic injectors can be activated in a protected way or activated by button. Button-actuated automatic injection devices include a push-button, typically located on the upper end of the device, which must be manipulated by the user to deliver an injection of the drug. Patients with AR have difficulties in activating these devices, due to the restriction imposed on the movements of their joints. summary

[002] In one embodiment, an auxiliary device for driving the injection is provided, including an upper side, a lower side, an opening in the lower side for receiving an injection device, and a shaft extending between the upper side and the lower side. bottom side.

The device further includes a chamber having a first end and a second end and enclosing the opening, the chamber being configured to receive a portion of the injection device and comprising a plurality of ribs extending into the chamber to grip the device. of injection. The device may additionally include a notch in the opening for receiving a bulge from the injection device when the injection device is received into the chamber, whereby receiving the injection device within the chamber and movement of the auxiliary device for actuation in the chamber toward the distal end of the injection device, trigger the injection device to deliver an injection.

[003] In another embodiment, a method for triggering an injection device is provided. The method includes placing an auxiliary device for driving the injection over the injection device, so that the injection device is partially disposed within the chamber of the auxiliary device, and at least one protrusion, on an external surface of the injection device, be aligned longitudinally with a notch in the auxiliary device. The method further includes inserting the injection device into the chamber of the auxiliary device until at least one protrusion of the injection device is removably received within the notch of the auxiliary device. The method further includes applying a downward force to the auxiliary device to drive the injection device to deliver an injection. Brief Description of Drawings

[004] A more particular description mentioned briefly above will be provided by reference to the specific embodiments thereof which are illustrated in the accompanying drawings. Understanding that these drawings represent typical embodiments only and are therefore not considered to limit their scope, the modalities will be described and explained with specificity and additional detail through the use of the attached drawings, in which:

[005] Figure 1 is a perspective view of an embodiment of the auxiliary device for driving the invention;

[006] Figure 2 is a side view of a modality of the auxiliary device for the injection drive;

[007] Figure 3 is a perspective bottom view of an auxiliary device modality for the injection drive;

[008] Figure 4 is a bottom view of a modality of the auxiliary device for triggering the injection;

[009] Figure 5 is a cross-sectional view of a modality of the auxiliary device for the injection drive;

[0010] Figure 6 is a top view of an embodiment of the auxiliary device for triggering injection, with an automatic injection device received therein;

[0011] Figure 7 is a top perspective view of an alternative embodiment of an auxiliary device for driving injection;

[0012] Figure 8 is a perspective cross-sectional view of an auxiliary device for triggering injection and an injection device for arrangement within the auxiliary device for triggering injection;

[0013] Figure 9 is a cross-sectional view of the injection device received inside the auxiliary device for the actuation;

[0014] Figure 10 is a cross-sectional view of the injection device attached inside the auxiliary device for driving injection for use. Detailed Description

[0015] For purposes of promoting an understanding of the principles and operation of the invention, reference will now be made to the embodiments illustrated in the drawings and specific language will be used to describe the same. It will, however, be understood that no limitation on the scope of the invention is thus intended, such additional changes and modifications to the device illustrated, and such additional applications of the principles of the invention as illustrated herein being contemplated as would normally be the case to one of ordinary skill in the art. which the invention belongs.

[0016] It should be noted that the terms "first", "second" and the like, as used herein, do not denote any order, quantity or importance, but rather are used to distinguish one element from another. The terms "one", "an" do not denote a quantity limitation, but rather denote the presence of at least one referenced item. Additionally, to the extent the terms "including", "includes", "having", "has", "with" or variations thereof are used in the detailed description and/or claims, such terms shall be inclusive in a similar way to the term " understanding". The modifier "about" used with respect to a quantity is inclusive of the mentioned value and has the meaning dictated by the context (eg, includes a degree of error associated with the measurement of the particular quantity). It should be noted that all ranges described within this specification are inclusive and are independently combinable.

[0017] The terminology used here is for the purpose of describing particular modalities only and should not be limiting. As used herein, the singular forms of "a", "an", and "the", "a" shall include the plural forms as well, unless the context clearly indicates otherwise these terms do not denote a limitation of quantity, but instead denote the presence of at least one of the items referred to. Additionally, to the extent the terms "including",

"includes", "having", "has", "with", or variations thereof are used in the detailed description and/or claims, such terms shall be inclusive in a similar way to the term "comprising". Furthermore, unless specifically mentioned, any use of the terms first, second, etc., does not denote any order, quantity, or importance, but rather, the terms first, second, etc., are used to distinguish one element from the other. other.

[0018] Notwithstanding the numerical ranges and parameters that configure the broad scope are approximations, the numerical values presented in the specific non-limiting examples are reported as accurately as possible. Any numerical value, however, inherently contains certain errors necessarily resulting from the standard deviation found in their respective test measurements. Furthermore, all ranges described herein should be understood to encompass any and all of the sub-ranges indicated here. As a non-limiting element, a range of "less than 10" may include all or any of the subranges between (and including) the minimum value of zero and the maximum value of 10, that is, all or any of the subranges having a minimum value equal to or greater than zero and a maximum value equal to or less than 10, for example from 1 to 7.

[0019] Turning to the drawings, Figure 1 is a perspective view of an auxiliary device for driving injection 100 including an upper side 102, a lower side 104, an opening 103 on the lower side for receiving an automatic injector ( opening illustrated in Figure 3), and an elongate shaft 106 extending between the upper side 102 and the lower side 104. The device 100 additionally includes an elongated chamber 108 (layer illustrated in Figures 4 and 5) having a first end 108a and a second end 108b and extending the length of the shaft 106 and ending at the opening 103, the chamber 108 being configured to receive a part of the automatic injection device 20 (illustrated in Figure 6) and comprising a plurality of channels 109 that intersect. extend between the first 108a and second 108b ends of the chamber to grip the automatic injection device 20. One or more anti-roll fittings, or stabilizers 111 are illustrated on page base art of device 100 in Figure 1. These anti-rolling fittings 111 prevent rolling of device 100 when disposed on a side surface.

[0020] In one embodiment, the auxiliary device for driving injection 100 may include a first coincident element, and the injection device may include a second coincident element, where the first and second coincident elements mutually engage to hold the auxiliary device for injection drive 100 and injection device 20 together during use. In some non-limiting examples, the first and second mating elements may include a notch and protrusion relationship, where one of the first or second mating elements includes a notch, and the other of the first or second mating elements includes a protrusion. In another non-limiting embodiment, the first mating element and/or the second mating element may include a part or surface of one device that is maintained by friction with another part or a surface of the other device.

[0021] In a non-limiting example, the first coincident element may include a notch 110, in one example, the notch 110 may be disposed in the opening 103 of the device 100 as illustrated in Figure 1. In a non-limiting embodiment, the second element mating may include a protrusion 22. The notch 110 may be configured to receive a protrusion from the injection device 20, in a non-limiting embodiment as illustrated in Figure 7,

when the automatic injection device 20 is received within the chamber 108 to keep the injection device 20 within the chamber 108 during use. Receiving the injection device 20 into the chamber 108 and applying a downward force on the auxiliary device for driving injection into the injection device 20, towards the distal end of the injection device 20, drives the injection device 20 to distribute an injection. Driving the injection device 20 in this way, with the auxiliary injection driving device 100, provides assistance to patients with little joint movement, and difficulty moving the fingers of the hand, as it eliminates the need to press the injection device. automatic injection down to inject a drug, while pressing the distal or lower end of the device against the target injection area to trigger the device to deliver an injection.

[0022] In addition, some patients have lost dexterity or simply strength in their hands, and consequently, triggering automatic injection devices (or any injection device) can be cumbersome. The injection actuation aid modalities 100 described herein facilitate the delivery of injection by these patients by transferring the push button actuation on a button actuated automatic injector, for example, to the injection actuation aid. The user simply supplies the downward force to the auxiliary device, while grasping an easy-to-hold shaft and grip of the device, rather than manipulating the device's trigger button while pressing the device down into the target injection area. When used with a protected trigger injection device, the auxiliary device for the injection trigger allows easier triggering of the automatic injection device,

providing a more ergonomically shaped object (i.e. the shaft) to grip while applying downward pressure towards a target injection site.

[0023] In some examples, the external profile of the auxiliary device for the injection actuation may include an ergonomic shape in an embodiment as illustrated in Figure 1, configured to be easily held within a user's hand to further facilitate the injection process. In some non-limiting embodiments, the external profile of the injection aid may include a longitudinal axis extending from the base of the device, for example. In other embodiments, various shapes, sizes and profiles may be used for the shaft portion of the injection aid device to improve the grip of the device during use. In further embodiments, surface treatments or material variations of the injection actuation auxiliary device 100 may be provided to improve a user's ability to hold and grip the device during use. Figure 7 provides a non-limiting example where the shaft includes a ribbed fitting on its outer surface.

[0024] With the modalities of the auxiliary device for triggering injection 100 described here, a user can simply apply pressure to the device 100 once the automatic injector is placed therein and applies pressure against the target injection site in order to to trigger the automatic injection device and dispense the injection.

[0025] Additionally, for push-button devices, where the push-button for the push-button is located on an upper surface of the appliance, the downward force on the auxiliary injection device 100 causes the push-button to actuate by pressing the push-button across the contact. between the button and the ceiling of the chamber 112. This action may cause movement between the button actuated injection device and the auxiliary device for the injection actuation.

[0026] Figure 2 is a side view of the embodiment of an auxiliary device for driving injection 100. In figure 2, the length a denotes the diameter of the lower side 104 of the device, and the diameter b of the upper side 102 is also illustrated. As shown in Figure 2, in one embodiment, the major diameter of the lower side b is greater than the major diameter of the upper side a. In a non-limiting embodiment, the underside 104 may include a rigid material. Underside 104 may include a flange 105 extending from the shaft. Flange 105 can be used to stabilize the device on the user's target surface. Flange 105 may be formed from a rigid material in a non-limiting embodiment. Materials may include plastics, rubbers and other materials known to those skilled in the art to which the invention pertains. The shaft 106 of the auxiliary device may be formed from a soft substrate material to assist in providing comfort to the user while using the auxiliary device 100. On the bottom surface of the device, a device receiving indicator 107 is illustrated. Device receive indicator 107 allows alignment of device within device 100 for receiving at that location. Upon receipt of an injection device (illustrated in Figures 7 to 10) within the injection drive auxiliary device 100, a bulge 22 on the outer surface of the injection device 20 should align with the device receipt indicator 107 to positioning the injection device for receiving and locking within the device 100. In some embodiments, the device receiving indicator may include an alignment guide. In other non-limiting embodiments, the device receiving indicator may indicate alignment and/or receipt of the injection device through visual, audible and/or tactile feedback.

[0027] Figure 3 is a perspective bottom view of an embodiment of the injection actuation auxiliary device 100 illustrating the opening 103 disposed on the underside 104 of the device 100, and a notch 110 positioned in the opening 103 receiving a bulge from a automatic injection device. Automatic injection devices routinely include bulges on their outer surface, these bulges are often referred to as "seeds". When received within the injection actuation auxiliary device 100, the proximal end of the automatic injector is located within the chamber 108, and the auxiliary device 100 is partially slid over the automatic injection device until the automatic injection device contacts the ceiling. of a camera 112 (illustrated in Figure 4) of the device 100.

[0028] Figure 4 is a bottom view of the embodiment of an auxiliary device for driving injection 100 illustrating a view inside the chamber 108. The notch 110, as illustrated in Figure 3, is illustrated as positioned in the opening 103 of the chamber 108 on the underside 104 of the device 100. An inside view of the chamber 108 illustrates the ceiling of the chamber 112 provided to support the automatic injection device during the use of the device 100. On the ceiling of the chamber 112 several protrusions 114 are provided for interfacing with the device 100. automatic injection device once put in place. A device receiving indicator 113 is illustrated on the bottom surface of device 100 in a non-limiting mode to indicate when an automatic injection device has been received within chamber 108.

[0029] Figure 5 is a cross-sectional view of an embodiment of an auxiliary device for driving injection 100 from the underside 104, with the notch 110 arranged in the opening 103 for the chamber

108. Figure 5 illustrates channels 109 for gripping the autoinjector once disposed therein. Channels 109 extend from the first end of the chamber 108a to the second end of the chamber 108b and provide additional friction to receive and hold the autoinjector within the chamber 108 during use of the device.

100.

[0030] Figure 6 is a top view of an embodiment of an auxiliary device for driving injection 100, illustrating a view from the top side 102, with an automatic injection device 20 and the flange. The anti-rolling fittings 111 can be seen associated with the underside 104 of the device 100 in the top view of the device 100.

[0031] Figure 7 is a top perspective view of an alternative embodiment of an auxiliary device for driving injection 200, illustrated receiving an injection device 20 within a chamber 208 of the auxiliary device 200. The auxiliary device for driving injection nozzle 200 includes an upper side 202 and a lower side 204, and a shaft 206 extending between the upper and lower sides 202, 204. The injection drive auxiliary device 200 includes, in a non-limiting embodiment, anti-rolling fittings 211 Furthermore, the axis 206 of the injection drive auxiliary device embodiment 200 is illustrated as an elongated vertical axis. Shaft 206 may be provided in any shape sufficient to be grasped in a user's hand to assist in triggering an injection by receiving an injection device within the chamber of auxiliary device 200. In some embodiments, an injection treatment surface can be provided on an external surface of the device. In one example, shaft 206 may include a ribbed surface as illustrated in Figure 7.

Certain materials, surface treatments, or device shapes can enhance a user's ability to grip and use device 200.

[0032] Figure 8 is a cross-sectional view of the embodiment of the auxiliary device for the injection drive 200 illustrated in Figure 7, with a cross-sectional view of an injection device 20 illustrated under the auxiliary device 200. A first coincident element 210, illustrated as a notch in figure 8, is disposed in an opening for the chamber 208 of the device 200. A second mating element 22, illustrated as a protrusion in the embodiment illustrated in figure 8, is provided on an external surface of the injection device 20. Then from aligning the protuberance 22 with the notch 210 and the insertion of the injection device 20 into the chamber 208 of the auxiliary device for the injection drive 200, as illustrated in Figure 9, the protuberance is received within the notch 210 to lock the injection device 20 to the auxiliary device for the injection drive 200 for use. The injection device 20 may be detachably locked to the injection auxiliary device 200, or may be permanently locked within the injection actuation auxiliary device 200 in alternative embodiments.

[0033] As illustrated in figure 10, after receiving the protuberance 22 inside the notches 210, and the rotation of the injection device 20 with respect to the auxiliary device for driving the injection 200, or the rotation of the auxiliary device for driving the injection 200 with respect to the injection device 20, or from the rotation of both components with respect to each other, the protuberance 22 is locked within the notch 210 for use of the device for delivering an injection.

[0034] In another embodiment, a method of driving an injection device 20 is provided. In one embodiment, the injection device may include an automatic injector. In additional non-limiting embodiments, the auto injector may include a button activated auto injector or a protected activated auto injector. The method includes placing the injection device 20 within the chamber of the auxiliary device for driving the injection 108, such that the automatic injection device 20 is at least partially disposed within the chamber 108 of the auxiliary device 100. In one embodiment, at least at least one protrusion 22 on an outer surface of the injection device 20 is longitudinally aligned with a notch 110 on the auxiliary device 100. The method further includes inserting the injection device 20 into the chamber 108 of the auxiliary device 100 until the upper surface of the auxiliary device 100 is injection device 20 contacts the ceiling of a chamber 112 of auxiliary device 100 until the injection device is secured within auxiliary device for driving injection 100, 200. In some embodiments, securing injection device 20 within auxiliary device for the injection drive 100, 200 requires rotation of the injection device 20 once it is placed inside the chamber. mara 108, 208, to secure the injection device 20 within the auxiliary device for driving the injection 100, 200. Rotation of the injection device 20 in the embodiment illustrated in Figures 7 to 10, for example, allows the bulge 22 to of the injection device 20 is received within the notches 210 of the auxiliary device for driving the injection 200. The method further includes applying a downward force to the auxiliary device 100 to trigger the automatic injection device 20 and delivering an injection through the device automatic injection 20.

[0035] It is important for an understanding of the present invention to note that all technical and scientific terms used herein, unless defined herein, shall have the same meaning as commonly understood by those skilled in the art. The techniques employed herein are also known to those skilled in the art, unless otherwise noted. For purposes of more clearly facilitating the understanding of the invention as described and claimed herein, the following definitions are provided.

[0036] While various embodiments of the present invention have been illustrated and described herein in the present context, such embodiments are provided by way of example only, and not limitation. Numerous variations, changes and substitutions will occur to those skilled in the art without materially departing from the invention presented herein. For example, the present invention need not be limited to the best way described herein, as other applications may benefit equally from the teachings of the present invention. Furthermore, in the claims, means plus function and step plus function clauses shall cover the structures and acts, respectively, described here as performing the mentioned function and not just structural equivalences or act equivalences, but all equivalent structures or equivalent acts, respectively. Accordingly, all said modifications shall be included within the scope of this invention as defined in the following claims, in accordance with the relevant law as to its interpretation.

Claims (22)

1. Auxiliary device for the injection drive, characterized in that it comprises: an upper side, a lower side, an opening in the lower side for receiving an injection device, and a shaft extending between the upper side and the lower side; a chamber comprising a first end and a second end, the chamber enclosing in the opening, said chamber configured to receive a part of the injection device; and a first mating element configured to interface with a second mating element in the injection device; wherein receiving the injection device within the chamber, and a distal movement of the actuation aid towards the injection device triggers the injection device to deliver an injection. 2. Auxiliary device for triggering injection, according to claim 1, characterized in that the injection device comprises an automatic injection device. 3. Auxiliary device for triggering injection, according to claim 2, characterized in that the automatic injection device comprises an automatic injection device activated by a button or an automatic injection device activated in a protected way. 4. Auxiliary device for triggering injection, according to claim 1, characterized in that the first coincident element comprises a notch. 5. Auxiliary device for triggering injection, according to claim 4, characterized in that the notch is arranged in the opening. 6. Auxiliary device for the injection drive, according to claim 4, characterized in that the first coincident element is configured to interface with a second coincident element in the injection device to secure the injection device within the auxiliary device for the injection drive. 7. Auxiliary device for the injection drive, according to claim 1, characterized in that the diameter of the lower side is greater than the diameter of the upper side. 8. Auxiliary device for the injection drive, according to claim 1, characterized in that it further comprises a flange extending from the underside of the device to stabilize the device at the target location. 9. Auxiliary device for the injection drive, according to claim 1, characterized in that the underside comprises a rigid material. 10. Auxiliary device for the injection drive, according to claim 4, characterized in that the receipt of the bulge of the automatic injection device inside the notch of the auxiliary device, and the rotation of the auxiliary device in relation to the injection device, lock the injection device in place for use. 11. Auxiliary device for the injection drive, according to claim 1, characterized in that it further comprises a chamber ceiling positioned at the upper end of the chamber, configured to support a first end of the injection device when received inside the chamber. 12. Auxiliary device for triggering injection, according to claim 11, characterized in that it further comprises a plurality of projections on the ceiling of the chamber to grip the injection device, or positioned inside the chamber. 13. Method of activating an automatic injection device, characterized in that it comprises: placing the auxiliary device for the injection activation, as defined in claim 1, on a part of an automatic injection device, so that the injection device automatic injection is partially arranged inside the chamber of the auxiliary device for actuation; inserting the automatic injection device into the chamber of the auxiliary device until an upper part of the automatic injection device contacts the ceiling of an auxiliary device chamber; and applying a distal force towards the injection device on the auxiliary device to trigger the automatic injection device and deliver an injection. 14. Method according to claim 13, characterized in that the automatic injection device is a push-button automatic injection device, and in which applying a distal force to the auxiliary device to activate the automatic injection device causes the automatic injection device button is pressed, starting an injection. 15. Method according to claim 13, characterized in that after inserting the automatic injection device into the chamber of the auxiliary device, at least one protrusion on an external surface of the automatic injection device is longitudinally aligned with a notch in the auxiliary device. 16. Method according to claim 15, characterized in that it further comprises rotating the auxiliary device until at least one protrusion of the automatic injection device is detachably received within the notch of the auxiliary device. 17. Method according to claim 13, characterized in that the automatic injection device is a protected-actuated automatic injection device, and in which applying a distal force to the auxiliary device to activate the automatic injection device causes the retraction of the guard into the automatic injection device, initiating an injection. 18. Method according to claim 13, characterized in that a bulge on the automatic injection device is aligned with a device receipt indicator prior to insertion into the chamber. A method as claimed in claim 18, wherein the device receipt indicator provides feedback based on the alignment or receipt of the device, said feedback including a visual, audible and/or tactile feedback. 20. Auxiliary device for triggering injection, according to claim 1, characterized in that it further comprises a plurality of ribs that extend into the chamber to contact the injection device in order to secure the injection device within the auxiliary device for triggering injection. 21. Auxiliary device for the injection drive, according to claim 2, characterized in that the ribs extend from the first end to the second end of the chamber. 22. Auxiliary device for the injection drive, characterized in that it comprises: an upper side, a lower side, an opening in the lower side for receiving an injection device, and a shaft extending between the upper side and the lower side; and a chamber comprising a first end and a second end, the chamber enclosing the opening, said chamber configured to receive and secure a part of the injection device; wherein the receipt of the injection device within the chamber and a distal movement of the actuation device towards the injection device triggers the injection device to deliver an injection.