BR112021012110A2 - Radiofarmacêuticos substituídos por aceptor de fluoreto de silício - Google Patents
Radiofarmacêuticos substituídos por aceptor de fluoreto de silício Download PDFInfo
- Publication number
- BR112021012110A2 BR112021012110A2 BR112021012110-2A BR112021012110A BR112021012110A2 BR 112021012110 A2 BR112021012110 A2 BR 112021012110A2 BR 112021012110 A BR112021012110 A BR 112021012110A BR 112021012110 A2 BR112021012110 A2 BR 112021012110A2
- Authority
- BR
- Brazil
- Prior art keywords
- bond
- group
- amino acid
- hydrophilic
- moiety
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/12—Organo silicon halides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19154636 | 2019-01-30 | ||
| EP19154636.5 | 2019-01-30 | ||
| PCT/EP2020/052159 WO2020157128A1 (en) | 2019-01-30 | 2020-01-29 | Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112021012110A2 true BR112021012110A2 (pt) | 2021-09-08 |
Family
ID=65268875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112021012110-2A BR112021012110A2 (pt) | 2019-01-30 | 2020-01-29 | Radiofarmacêuticos substituídos por aceptor de fluoreto de silício |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12576169B2 (https=) |
| EP (1) | EP3917581A1 (https=) |
| JP (1) | JP7421232B2 (https=) |
| CN (1) | CN113677375B (https=) |
| AU (1) | AU2020213892B2 (https=) |
| BR (1) | BR112021012110A2 (https=) |
| WO (1) | WO2020157128A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202005282D0 (en) | 2020-04-09 | 2020-05-27 | Blue Earth Diagnostics Ltd | Pharmaceutical Formulations |
| WO2022018264A1 (en) * | 2020-07-23 | 2022-01-27 | Technische Universität München | Silicon-containing ligand compounds |
| JP2024544153A (ja) | 2021-11-16 | 2024-11-28 | テクニシェ ユニバーシタット ミュンヘン | 溶解した［１８ｆ］フッ化物を含む組成物の調製方法およびその方法によって得ることができる組成物 |
| GB202207372D0 (en) | 2022-05-19 | 2022-07-06 | Blue Earth Diagnostics Ltd | Synthesis of fluorosilyl compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR057023A1 (es) | 2005-05-16 | 2007-11-14 | Gilead Sciences Inc | Compuestos heterociclicos con propiedades inhibidoras de hiv-integrasa |
| PL2187965T3 (pl) | 2007-08-17 | 2020-05-18 | Purdue Research Foundation | Koniugaty wiążący psma ligand-łącznik i sposoby ich zastosowania |
| EP3209336B1 (en) | 2014-10-20 | 2019-12-11 | Deutsches Krebsforschungszentrum | 18f-tagged inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer |
| US10800797B2 (en) | 2015-05-26 | 2020-10-13 | California Institute Of Technology | Heteroaromatic silicon-fluoride-acceptors useful for 18F labeling of molecules and biomolecules, and methods of preparing same |
| HUE070098T2 (hu) | 2017-07-28 | 2025-05-28 | Univ Muenchen Tech | Kettõs módusú radioaktív jelzõ és terapeutikumok |
-
2020
- 2020-01-29 BR BR112021012110-2A patent/BR112021012110A2/pt unknown
- 2020-01-29 US US17/425,430 patent/US12576169B2/en active Active
- 2020-01-29 JP JP2021544519A patent/JP7421232B2/ja active Active
- 2020-01-29 CN CN202080017181.2A patent/CN113677375B/zh active Active
- 2020-01-29 EP EP20702465.4A patent/EP3917581A1/en active Pending
- 2020-01-29 WO PCT/EP2020/052159 patent/WO2020157128A1/en not_active Ceased
- 2020-01-29 AU AU2020213892A patent/AU2020213892B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2022518598A (ja) | 2022-03-15 |
| EP3917581A1 (en) | 2021-12-08 |
| CN113677375B (zh) | 2024-07-23 |
| WO2020157128A1 (en) | 2020-08-06 |
| CA3123738A1 (en) | 2020-08-06 |
| AU2020213892B2 (en) | 2025-04-10 |
| JP7421232B2 (ja) | 2024-01-24 |
| AU2020213892A1 (en) | 2021-07-22 |
| US20220096669A1 (en) | 2022-03-31 |
| CN113677375A (zh) | 2021-11-19 |
| US12576169B2 (en) | 2026-03-17 |
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