BR112020019172A2 - tratamento e profilaxia de amiloidose - Google Patents
tratamento e profilaxia de amiloidose Download PDFInfo
- Publication number
- BR112020019172A2 BR112020019172A2 BR112020019172-8A BR112020019172A BR112020019172A2 BR 112020019172 A2 BR112020019172 A2 BR 112020019172A2 BR 112020019172 A BR112020019172 A BR 112020019172A BR 112020019172 A2 BR112020019172 A2 BR 112020019172A2
- Authority
- BR
- Brazil
- Prior art keywords
- antibody
- seq
- amino acid
- use according
- concentration
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862647341P | 2018-03-23 | 2018-03-23 | |
| US62/647,341 | 2018-03-23 | ||
| PCT/US2019/023528 WO2019183448A1 (en) | 2018-03-23 | 2019-03-22 | Treatment and prophylaxis of amyloidosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112020019172A2 true BR112020019172A2 (pt) | 2021-01-26 |
Family
ID=66041747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112020019172-8A BR112020019172A2 (pt) | 2018-03-23 | 2019-03-22 | tratamento e profilaxia de amiloidose |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20210017278A1 (https=) |
| EP (1) | EP3768311A1 (https=) |
| JP (1) | JP7217287B2 (https=) |
| KR (1) | KR20200143400A (https=) |
| CN (1) | CN112040983A (https=) |
| AU (2) | AU2019240413A1 (https=) |
| BR (1) | BR112020019172A2 (https=) |
| CA (1) | CA3095100A1 (https=) |
| EA (1) | EA202092264A1 (https=) |
| MX (1) | MX2020009920A (https=) |
| MY (1) | MY203432A (https=) |
| SG (1) | SG11202009295YA (https=) |
| WO (1) | WO2019183448A1 (https=) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2237803T3 (en) * | 2007-12-28 | 2015-10-05 | Prothena Biosciences Ltd | Treatment and prophylaxis of amyloidosis |
| SG10201604104PA (en) * | 2011-10-25 | 2016-07-28 | Prothena Therapeutics Ltd | Antibody formulations and methods |
| WO2018005967A1 (en) * | 2016-06-30 | 2018-01-04 | Prothena Therapeutics Limited | Compositions for treating amyloidosis |
-
2019
- 2019-03-22 MX MX2020009920A patent/MX2020009920A/es unknown
- 2019-03-22 KR KR1020207030523A patent/KR20200143400A/ko not_active Ceased
- 2019-03-22 WO PCT/US2019/023528 patent/WO2019183448A1/en not_active Ceased
- 2019-03-22 AU AU2019240413A patent/AU2019240413A1/en not_active Abandoned
- 2019-03-22 CA CA3095100A patent/CA3095100A1/en active Pending
- 2019-03-22 MY MYPI2020004912A patent/MY203432A/en unknown
- 2019-03-22 EP EP19715723.3A patent/EP3768311A1/en active Pending
- 2019-03-22 CN CN201980028739.4A patent/CN112040983A/zh active Pending
- 2019-03-22 BR BR112020019172-8A patent/BR112020019172A2/pt not_active Application Discontinuation
- 2019-03-22 US US17/040,343 patent/US20210017278A1/en not_active Abandoned
- 2019-03-22 JP JP2020550650A patent/JP7217287B2/ja active Active
- 2019-03-22 EA EA202092264A patent/EA202092264A1/ru unknown
- 2019-03-22 SG SG11202009295YA patent/SG11202009295YA/en unknown
-
2023
- 2023-04-05 AU AU2023202109A patent/AU2023202109A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3768311A1 (en) | 2021-01-27 |
| MY203432A (en) | 2024-06-27 |
| CN112040983A (zh) | 2020-12-04 |
| CA3095100A1 (en) | 2019-09-26 |
| KR20200143400A (ko) | 2020-12-23 |
| AU2023202109A1 (en) | 2023-05-18 |
| EA202092264A1 (ru) | 2020-12-03 |
| JP7217287B2 (ja) | 2023-02-02 |
| WO2019183448A1 (en) | 2019-09-26 |
| AU2019240413A1 (en) | 2020-10-08 |
| MX2020009920A (es) | 2020-12-10 |
| US20210017278A1 (en) | 2021-01-21 |
| JP2021518393A (ja) | 2021-08-02 |
| SG11202009295YA (en) | 2020-10-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10517830B2 (en) | Antibody formulations and methods | |
| RU2322261C2 (ru) | Применение ингибиторов миостатика (gdf8) в сочетании с кортикостероидами для лечения нервно-мышечных заболеваний | |
| US20210079078A1 (en) | Compositions for Treating Amyloidosis | |
| US20220340668A1 (en) | Treatment of liver disease or disorder comprising actrii receptor antagonists | |
| EP3934689A1 (en) | Methods of treating al amyloidosis | |
| BR112021003093A2 (pt) | tratamento de câncer de mama triplo negativo que visa a inibição de tgf-beta | |
| US20250075007A1 (en) | Treatment of Al Amyloidosis with the Combination of Monoclonal Antibodies Agains Immunoglobulin Light Chains and the CD38 Cell Membrane Molecule on Antibody-Producing And Other Immune Cells | |
| BR112020019172A2 (pt) | tratamento e profilaxia de amiloidose | |
| WO2023174408A1 (zh) | 抗tim-3抗体与抗pd-l1抗体的药物组合 | |
| WO2022162625A1 (en) | Methods of treating al amyloidosis | |
| EA044759B1 (ru) | Лечение и профилактика амилоидоза | |
| TW201946652A (zh) | 康納單抗(canakinumab)之用途 | |
| HK40008815B (en) | Compositions for treating amyloidosis | |
| HK40102408B (zh) | 含抗lag-3抗体的药物组合物及其用途 | |
| HK40102408A (zh) | 含抗lag-3抗体的药物组合物及其用途 | |
| WO2025170969A1 (en) | Methods of treating al amyloidosis | |
| EA048260B1 (ru) | Способы лечения al-амилоидоза | |
| JP2020533353A (ja) | アルコール性肝炎の治療のためのｉｌ−１ｂ結合抗体の使用 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |