BR112019026225A2 - composições de pasta polimérica para liberação de fármacos - Google Patents
composições de pasta polimérica para liberação de fármacos Download PDFInfo
- Publication number
- BR112019026225A2 BR112019026225A2 BR112019026225-3A BR112019026225A BR112019026225A2 BR 112019026225 A2 BR112019026225 A2 BR 112019026225A2 BR 112019026225 A BR112019026225 A BR 112019026225A BR 112019026225 A2 BR112019026225 A2 BR 112019026225A2
- Authority
- BR
- Brazil
- Prior art keywords
- peg
- plga
- drug
- composition according
- molecular weight
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
- C08G63/08—Lactones or lactides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/66—Polyesters containing oxygen in the form of ether groups
- C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Gynecology & Obstetrics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762518800P | 2017-06-13 | 2017-06-13 | |
| US62/518,800 | 2017-06-13 | ||
| PCT/CA2018/050714 WO2018227293A1 (en) | 2017-06-13 | 2018-06-13 | Polymeric paste compositions for drug delivery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112019026225A2 true BR112019026225A2 (pt) | 2020-06-30 |
Family
ID=64658910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112019026225-3A BR112019026225A2 (pt) | 2017-06-13 | 2018-06-13 | composições de pasta polimérica para liberação de fármacos |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11167034B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3638311A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP7254719B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN110740752B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2018285975B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112019026225A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3067269C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018227293A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
| US20200155449A1 (en) | 2015-11-16 | 2020-05-21 | Medincell | Method for morselizing and/or targeting pharmaceutically active principles to synovial tissue |
| AU2018285975B2 (en) * | 2017-06-13 | 2023-11-16 | The University Of British Columbia | Polymeric paste compositions for drug delivery |
| WO2019071245A1 (en) | 2017-10-06 | 2019-04-11 | Foundry Therapeutics, Inc. | IMPLANTABLE DEPOSITS FOR REGULATED RELEASE OF ANALGESICS TO TREAT POSTHOPERATIVE PAIN ASSOCIATED WITH ORTHOPEDIC SURGERY, AND RELATED DEVICES, SYSTEMS, AND METHODS |
| CN116650732A (zh) | 2018-01-08 | 2023-08-29 | 铸造疗法股份有限公司 | 经由治疗剂的控制递送用于治疗腔内癌症的装置、系统和方法 |
| US12458589B2 (en) | 2018-05-12 | 2025-11-04 | Foundry Therapeutics, Inc. | Implantable polymer depots for the controlled release of therapeutic agents |
| WO2020047013A1 (en) | 2018-08-28 | 2020-03-05 | Foundry Therapeutics, Inc. | Polymer implants |
| CN119950395A (zh) * | 2019-04-11 | 2025-05-09 | 铸造疗法股份有限公司 | 用于治疗癌症和相关症状和病症的治疗剂的局部、持续、受控释放的可植入贮存库 |
| CA3167259A1 (en) * | 2020-02-07 | 2021-08-12 | Veronika SCHMITT | Mucoadhesive polymeric drug delivery compositions and methods |
| WO2024168423A1 (en) * | 2023-02-14 | 2024-08-22 | 1376683 B.C. Ltd | Topical copolymer formulations for hydrophobic drug delivery |
| WO2025058571A1 (en) * | 2023-09-15 | 2025-03-20 | Agency For Science, Technology And Research | Polymer composition comprising a thermogelling polymer and a tyrosine kinase inhibitor, and related methods thereof |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6217911B1 (en) | 1995-05-22 | 2001-04-17 | The United States Of America As Represented By The Secretary Of The Army | sustained release non-steroidal, anti-inflammatory and lidocaine PLGA microspheres |
| KR0180334B1 (ko) * | 1995-09-21 | 1999-03-20 | 김윤 | 블럭 공중합체 미셀을 이용한 약물전달체 및 이에 약물을 봉입하는 방법 |
| US6187640B1 (en) | 1998-11-17 | 2001-02-13 | Fujitsu Limited | Semiconductor device manufacturing method including various oxidation steps with different concentration of chlorine to form a field oxide |
| DE19701912C1 (de) | 1997-01-10 | 1998-05-14 | Jenapharm Gmbh | Injizierbares Implantat |
| US6193991B1 (en) | 1997-10-29 | 2001-02-27 | Atul J. Shukla | Biodegradable delivery systems of biologically active substances |
| US6451335B1 (en) | 1998-07-02 | 2002-09-17 | Euro-Celtique S.A. | Formulations and methods for providing prolonged local anesthesia |
| US6349306B1 (en) | 1998-10-30 | 2002-02-19 | Aprisma Management Technologies, Inc. | Method and apparatus for configuration management in communications networks |
| KR100360827B1 (ko) | 1999-08-14 | 2002-11-18 | 주식회사 삼양사 | 난용성 약물을 가용화하기 위한 고분자 조성물 및 그의 제조방법 |
| KR100416242B1 (ko) * | 1999-12-22 | 2004-01-31 | 주식회사 삼양사 | 약물전달체용 생분해성 블록 공중합체의 액체 조성물 및이의 제조방법 |
| DE60220519T2 (de) | 2001-04-20 | 2007-09-27 | The University Of British Columbia, Vancouver | Mizellares arzneistoffverabreichungssystem für hydrophobe arzneistoffe |
| US6623729B2 (en) | 2001-07-09 | 2003-09-23 | Korea Advanced Institute Of Science And Technology | Process for preparing sustained release micelle employing conjugate of anticancer drug and biodegradable polymer |
| US6913760B2 (en) | 2001-08-06 | 2005-07-05 | New England Medical Hospitals, Inc. | Drug delivery composition |
| US7649023B2 (en) * | 2002-06-11 | 2010-01-19 | Novartis Ag | Biodegradable block copolymeric compositions for drug delivery |
| RU2355385C2 (ru) | 2002-11-06 | 2009-05-20 | Алза Корпорейшн | Композиции пролонгированного действия с контролируемым высвобождением |
| DK1635875T3 (da) * | 2003-06-26 | 2009-01-12 | Psivida Inc | In-situ-geldannende lægemiddeladministrationssystem |
| AU2003272127A1 (en) * | 2003-10-24 | 2005-05-11 | Samyang Corporation | Polymeric composition for drug delivery |
| AU2004313245B2 (en) | 2003-12-30 | 2011-04-14 | Durect Corporation | Polymeric implants, preferably containing a mixture of PEG and PLG, for controlled release of active agents, preferably a GNRH |
| EP1604693A1 (en) * | 2004-06-09 | 2005-12-14 | Scil Technology GmbH | In situ forming scaffold, its manufacturing and use |
| US20090285873A1 (en) * | 2008-04-18 | 2009-11-19 | Abbott Cardiovascular Systems Inc. | Implantable medical devices and coatings therefor comprising block copolymers of poly(ethylene glycol) and a poly(lactide-glycolide) |
| US8846068B2 (en) | 2008-04-18 | 2014-09-30 | Warsaw Orthopedic, Inc. | Methods and compositions for treating post-operative pain comprising a local anesthetic |
| RU2504360C2 (ru) * | 2008-08-12 | 2014-01-20 | Новартис Аг | Фармацевтические композиции |
| US9161903B2 (en) | 2008-10-31 | 2015-10-20 | Warsaw Orthopedic, Inc. | Flowable composition that hardens on delivery to a target tissue site beneath the skin |
| US8980317B2 (en) | 2008-12-23 | 2015-03-17 | Warsaw Orthopedic, Inc. | Methods and compositions for treating infections comprising a local anesthetic |
| US8623396B2 (en) | 2010-12-03 | 2014-01-07 | Warsaw Orthopedic, Inc. | Compositions and methods for delivering clonidine and bupivacaine to a target tissue site |
| US10449152B2 (en) | 2014-09-26 | 2019-10-22 | Covidien Lp | Drug loaded microspheres for post-operative chronic pain |
| CN106511261A (zh) * | 2016-12-06 | 2017-03-22 | 贵阳中医学院 | 一种替代针灸埋植用羊肠线的可注射原位凝胶 |
| AU2018285975B2 (en) * | 2017-06-13 | 2023-11-16 | The University Of British Columbia | Polymeric paste compositions for drug delivery |
-
2018
- 2018-06-13 AU AU2018285975A patent/AU2018285975B2/en active Active
- 2018-06-13 BR BR112019026225-3A patent/BR112019026225A2/pt not_active Application Discontinuation
- 2018-06-13 EP EP18817738.0A patent/EP3638311A4/en active Pending
- 2018-06-13 CN CN201880039808.7A patent/CN110740752B/zh active Active
- 2018-06-13 CA CA3067269A patent/CA3067269C/en active Active
- 2018-06-13 WO PCT/CA2018/050714 patent/WO2018227293A1/en not_active Ceased
- 2018-06-13 US US16/619,427 patent/US11167034B2/en active Active
- 2018-06-13 JP JP2019566745A patent/JP7254719B2/ja active Active
-
2021
- 2021-10-08 US US17/497,766 patent/US20220152207A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN110740752A (zh) | 2020-01-31 |
| JP2020523303A (ja) | 2020-08-06 |
| US11167034B2 (en) | 2021-11-09 |
| JP7254719B2 (ja) | 2023-04-10 |
| CN110740752B (zh) | 2023-11-17 |
| WO2018227293A1 (en) | 2018-12-20 |
| AU2018285975B2 (en) | 2023-11-16 |
| CA3067269A1 (en) | 2018-12-20 |
| CA3067269C (en) | 2024-01-09 |
| US20200147223A1 (en) | 2020-05-14 |
| EP3638311A1 (en) | 2020-04-22 |
| US20220152207A1 (en) | 2022-05-19 |
| EP3638311A4 (en) | 2020-12-16 |
| AU2018285975A1 (en) | 2020-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B12B | Appeal against refusal [chapter 12.2 patent gazette] |