BR112019008954A2 - dispositivos e métodos para geração de pasta fluida - Google Patents

dispositivos e métodos para geração de pasta fluida

Info

Publication number
BR112019008954A2
BR112019008954A2 BR112019008954A BR112019008954A BR112019008954A2 BR 112019008954 A2 BR112019008954 A2 BR 112019008954A2 BR 112019008954 A BR112019008954 A BR 112019008954A BR 112019008954 A BR112019008954 A BR 112019008954A BR 112019008954 A2 BR112019008954 A2 BR 112019008954A2
Authority
BR
Brazil
Prior art keywords
slurry
cold
cold slurry
fluid
cooling
Prior art date
Application number
BR112019008954A
Other languages
English (en)
Inventor
J P Velis Christopher
C Velis Cole
Miller Karen
Original Assignee
J P Velis Christopher
C Velis Cole
Miller Karen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by J P Velis Christopher, C Velis Cole, Miller Karen filed Critical J P Velis Christopher
Publication of BR112019008954A2 publication Critical patent/BR112019008954A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B18/0218—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques with open-end cryogenic probe, e.g. for spraying fluid directly on tissue or via a tissue-contacting porous tip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/0085—Devices for generating hot or cold treatment fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
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    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/11—Stirrers characterised by the configuration of the stirrers
    • B01F27/112—Stirrers characterised by the configuration of the stirrers with arms, paddles, vanes or blades
    • B01F27/1121—Stirrers characterised by the configuration of the stirrers with arms, paddles, vanes or blades pin-shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/11—Stirrers characterised by the configuration of the stirrers
    • B01F27/13—Openwork frame or cage stirrers not provided for in other groups of this subclass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
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    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/449—Stirrers constructions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B01F33/50112—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held of the syringe or cartridge type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32—Driving arrangements
    • B01F35/32005—Type of drive
    • B01F35/3202—Hand driven
    • B01F35/32021—Shaking by hand a portable receptacle or stirrer for mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/56—General build-up of the mixers
    • B01F35/562—General build-up of the mixers the mixer or mixing elements being collapsible, i.e. when discharging the products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/713—Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B01F35/7131—Breaking or perforating packages, containers or vials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/713—Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B01F35/7138—Opening valves which close-off openings between compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms
    • B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
    • B01F35/75425—Discharge mechanisms characterised by the means for discharging the components from the mixer using pistons or plungers
    • B01F35/754251—Discharge mechanisms characterised by the means for discharging the components from the mixer using pistons or plungers reciprocating in the mixing receptacle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/90—Heating or cooling systems
    • B01F35/92—Heating or cooling systems for heating the outside of the receptacle, e.g. heated jackets or burners
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452—Skin
    • A61B2018/00458—Deeper parts of the skin, e.g. treatment of vascular disorders or port wine stains
    • A61B2018/00464—Subcutaneous fat, e.g. liposuction, lipolysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0293—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument interstitially inserted into the body, e.g. needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0059—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit
    • A61F2007/0063—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit for cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0282—Compresses or poultices for effecting heating or cooling for particular medical treatments or effects
    • A61F2007/029—Fat cell removal or destruction by non-ablative heat treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2026—Semi-automatic, e.g. user activated piston is assisted by additional source of energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3606—General characteristics of the apparatus related to heating or cooling cooled
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/90—Heating or cooling systems
    • B01F2035/98—Cooling

Abstract

a presente invenção envolve o uso de um pequeno dispositivo de perfil para preparação e/ou entrega de pasta fluida fria no corpo humano. a pasta fluida fria pode ser gerada dentro do próprio dispositivo ou dentro de uma câmara pequena separada, ambos dos quais produzem uma pasta fluida fria usando uma fonte de arrefecimento e um fluido injetável. o dispositivo de entrega fornece agitação contínua ao fluido/ pasta fluida através de rotação e/ou vibração de lâminas dentro do dispositivo. o fluido/pasta fluida fria é arrefecido/mantido arrefecido através do uso de um dispositivo de arrefecimento externo, tal como uma manga de arrefecimento, que pelo menos parcialmente circunda o dispositivo de entrega. a manga de arrefecimento pode arrefecer ou reter a temperatura da pasta fluida fria através de vários mecanismos. a pasta fluida fria pode ser entregue usando um dispositivo de acordo com a presente invenção para qualquer tecido dentro do corpo, incluindo gordura subcutânea, gordura visceral, e gordura marrom.
BR112019008954A 2016-11-02 2017-10-31 dispositivos e métodos para geração de pasta fluida BR112019008954A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662416484P 2016-11-02 2016-11-02
PCT/US2017/059153 WO2018085212A1 (en) 2016-11-02 2017-10-31 Devices and methods for slurry generation

Publications (1)

Publication Number Publication Date
BR112019008954A2 true BR112019008954A2 (pt) 2019-07-09

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ID=62020794

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019008954A BR112019008954A2 (pt) 2016-11-02 2017-10-31 dispositivos e métodos para geração de pasta fluida

Country Status (17)

Country Link
US (2) US11000409B2 (pt)
EP (2) EP3534852B1 (pt)
JP (2) JP7026874B2 (pt)
KR (1) KR20200020657A (pt)
CN (2) CN110392561B (pt)
AU (1) AU2017355364A1 (pt)
BR (1) BR112019008954A2 (pt)
CA (1) CA3042402A1 (pt)
DK (1) DK3534852T3 (pt)
ES (1) ES2908654T3 (pt)
IL (1) IL266283A (pt)
MX (1) MX2019005153A (pt)
PL (1) PL3534852T3 (pt)
PT (1) PT3534852T (pt)
SG (1) SG11201903946SA (pt)
WO (1) WO2018085212A1 (pt)
ZA (1) ZA201903072B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112017003143B1 (pt) 2014-08-28 2023-12-05 The General Hospital Corporation Suspensões injetáveis, métodos para fabricação das mesmas e seus usos
MX2019005153A (es) * 2016-11-02 2019-11-12 J P Velis Christopher Dispositivos y métodos para la generación de una suspensión acuosa espesa.
US11324673B2 (en) 2016-11-18 2022-05-10 Miraki Innovation Think Tank Llc Cosmetic appearance of skin
BR112019020969A8 (pt) 2017-04-05 2022-11-16 Miraki Innovation Think Tank Llc Contenção de pasta fluida fria
WO2018187573A1 (en) 2017-04-05 2018-10-11 Arctic Fox Biomedical, Inc. Point of delivery cold slurry generation
US10500342B2 (en) * 2017-08-21 2019-12-10 Miraki Innovation Think Tank Llc Cold slurry syringe
RU2695892C1 (ru) * 2018-07-13 2019-07-29 Федеральное государственное автономное образовательное учреждение высшего образования "Северо-Восточный федеральный университет имени М.К.Аммосова" Способ профилактики и коррекции снижения минеральной плотности костной ткани при состояниях и заболеваниях, приводящих к остеопении и остеопорозу
US20210346192A1 (en) * 2018-10-10 2021-11-11 Miraki Innovation Think Tank Llc Systems and methods of generating cold slurry for injection
BR112021006899A2 (pt) * 2018-10-10 2021-07-20 Miraki Innovation Think Tank Llc sistema e método para gerar uma pasta fluida
WO2020077072A1 (en) * 2018-10-12 2020-04-16 Miraki Innovation Think Tank Llc Cold solution for fat reduction
FR3090401B1 (fr) * 2018-12-21 2023-04-28 Seb Sa Appareil de fabrication, machine à mélange et/ou dispositif de réception pour la fabrication d’une composition à partir d’un mélange de formulations
CA3162660A1 (en) * 2019-12-24 2021-07-01 Christopher VELIS Substantially solid solution, systems and methods for generating a substantially solid solution, and methods of administration thereof
WO2021212275A1 (en) * 2020-04-20 2021-10-28 Covidien Lp Motorized mixing device for use with medical agents
TWI731660B (zh) * 2020-04-24 2021-06-21 透策生技股份有限公司 利用加壓手段以加速注射式填充物分散的處理方法
TWI745942B (zh) * 2020-04-24 2021-11-11 透策生技股份有限公司 利用負壓手段以加速注射式填充物分散的處理方法
JP2023537466A (ja) 2020-07-10 2023-09-01 シー チェンジ サージカル エルエルシー 注入可能スラッシュ給送供給
US20230285186A1 (en) * 2020-08-07 2023-09-14 Miraki Innovation Think Tank Llc Compositions, systems and methods for treating brown fat and beige fat
US20220071900A1 (en) * 2020-09-08 2022-03-10 Brixton Biosciences, Inc. Systems and methods for preparing and transporting an injectable slurry
US11241330B1 (en) * 2021-04-02 2022-02-08 Brixton Biosciences, Inc. Apparatus for creation of injectable slurry
CN113198351A (zh) * 2021-05-24 2021-08-03 广东笑咪咪食品有限公司 一种原料混合搅拌装置

Family Cites Families (138)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3373906A (en) * 1967-02-10 1968-03-19 Haart Inc De Syringe with stirrer
US3893834A (en) * 1974-03-04 1975-07-08 Arthur E Armstrong Insulated cold pack
US4619678A (en) * 1983-12-20 1986-10-28 Howard Rubin Apparatus and method for transporting and preserving perishable test samples
US4983045A (en) 1985-11-22 1991-01-08 Reica Corporation Mixer
US5143063A (en) 1988-02-09 1992-09-01 Fellner Donald G Method of removing adipose tissue from the body
JP2512095B2 (ja) 1988-08-12 1996-07-03 株式会社日立製作所 冷熱発生方法
EP0418979A3 (en) * 1989-09-21 1992-03-04 Michele Dr. Zocchi Method and apparatus for producing human autologous collagen
US5071040A (en) * 1990-03-09 1991-12-10 Pfizer Hospital Products Group, Inc. Surgical adhesives mixing and dispensing implement
US5304128A (en) 1992-09-22 1994-04-19 Habley Medical Technology Corporation Gas powered self contained syringe
US5507790A (en) 1994-03-21 1996-04-16 Weiss; William V. Method of non-invasive reduction of human site-specific subcutaneous fat tissue deposits by accelerated lipolysis metabolism
US5769879A (en) 1995-06-07 1998-06-23 Medical Contouring Corporation Microwave applicator and method of operation
US6464697B1 (en) 1998-02-19 2002-10-15 Curon Medical, Inc. Stomach and adjoining tissue regions in the esophagus
SK51699A3 (en) * 1996-10-23 1999-10-08 Henry G Wolsey Cooling pouch
US5910104A (en) 1996-12-26 1999-06-08 Cryogen, Inc. Cryosurgical probe with disposable sheath
US6032675A (en) 1997-03-17 2000-03-07 Rubinsky; Boris Freezing method for controlled removal of fatty tissue by liposuction
AU6865298A (en) 1997-03-17 1998-10-12 Boris Rubinsky The use of cryoprotective agent compounds during cryosurgery
GB2338428A (en) * 1998-06-19 1999-12-22 David Grant A syringe with an agitator whose shaft passes through a slidable dispensing plunger
US6300130B1 (en) 1998-11-16 2001-10-09 The General Hospital Corporation And University Of Massachusetts Ultra rapid freezing for cell cryopreservation
US6403376B1 (en) 1998-11-16 2002-06-11 General Hospital Corporation Ultra rapid freezing for cell cryopreservation
US6324863B1 (en) 1999-03-05 2001-12-04 Imi Cornelius Inc. Sanitary ice making system
US6334328B1 (en) 1999-03-12 2002-01-01 Imi Cornelius Inc. Sanitary ice making and dispensing apparatus
JP3111219B1 (ja) 1999-05-25 2000-11-20 工業技術院長 ポリビニルアルコールを利用した冷熱輸送方法及び装置
US7422601B2 (en) 1999-08-02 2008-09-09 University Of Chicago Office Of Technology Transfer Method for inducing hypothermia
US6962601B2 (en) 1999-08-02 2005-11-08 University Of Chicago Office Of Technology Transfer Method for inducing hypothermia
US6413444B1 (en) 1999-08-02 2002-07-02 The University Of Chicago Methods and apparatus for producing phase change ice particulate saline slurries
US6547811B1 (en) 1999-08-02 2003-04-15 Arch Development Corporation Method for inducing hypothermia
US6244052B1 (en) 1999-08-02 2001-06-12 The University Of Chicago Method and apparatus for producing phase change ice particulate perfluorocarbon slurries
AU6519100A (en) 1999-08-05 2001-03-05 Biocardia, Inc. A system and method for delivering thermally sensitive and reverse-thermal gelation matrials
EP1274377A2 (en) 2000-04-07 2003-01-15 The General Hospital Corporation doing business as Massachusetts General Hospital Methods and apparatus for thermally affecting tissue
US20020045156A1 (en) 2000-05-16 2002-04-18 Mehmet Toner Microinjection of cryoprotectants for preservation of cells
US7255865B2 (en) 2000-12-05 2007-08-14 Allergan, Inc. Methods of administering botulinum toxin
EP1384036B1 (en) 2001-03-27 2005-01-26 Skaginn HF A method and apparatus for producing fluid ice
US6547432B2 (en) * 2001-07-16 2003-04-15 Stryker Instruments Bone cement mixing and delivery device for injection and method thereof
US20030032996A1 (en) 2001-08-08 2003-02-13 Hallman Arlan Jay Cryogenic massage tube and compress
US6571564B2 (en) 2001-10-23 2003-06-03 Shashank Upadhye Timed container warmer and cooler
CH695758A5 (de) * 2002-03-05 2006-08-31 Tecpharma Licensing Ag Kühlvorrichtung für Injektionsgeräte.
ATE386491T1 (de) 2002-03-15 2008-03-15 Gen Hospital Corp Vorrichtungen für die selektive zerstörung von fettgewebe durch kontrollierte kühlung
US8840608B2 (en) 2002-03-15 2014-09-23 The General Hospital Corporation Methods and devices for selective disruption of fatty tissue by controlled cooling
US8361067B2 (en) 2002-09-30 2013-01-29 Relievant Medsystems, Inc. Methods of therapeutically heating a vertebral body to treat back pain
US7118591B2 (en) 2003-04-17 2006-10-10 The University Of Chicago Heat transfer probe
US7654997B2 (en) 2004-04-21 2010-02-02 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat
US20060036302A1 (en) 2004-05-28 2006-02-16 Kasza Kenneth E Methods of inducing protective hypothermia of organs
US20060161232A1 (en) * 2005-01-18 2006-07-20 Kasza, Oras and Son to The University of Chicago Phase-change particulate ice slurry coolant medical delivery tubing and insertion devices
EP1848491A4 (en) 2005-02-09 2009-08-19 Childrens Medical Center DEVICE FOR MIXING AND DELIVERING FLUIDS FOR TISSUE REPAIR
US7713266B2 (en) 2005-05-20 2010-05-11 Myoscience, Inc. Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat)
US7967763B2 (en) 2005-09-07 2011-06-28 Cabochon Aesthetics, Inc. Method for treating subcutaneous tissues
US7389653B2 (en) * 2005-09-15 2008-06-24 The University Of Chicago Medical ice slurry production device
US20070093697A1 (en) 2005-10-21 2007-04-26 Theranova, Llc Method and apparatus for detection of right to left shunting in the cardiopulmonary vasculature
US7681411B2 (en) 2006-01-17 2010-03-23 Dilorenzo Thomas Ice making and dispensing method and apparatus with increased sanitation
US7854754B2 (en) 2006-02-22 2010-12-21 Zeltiq Aesthetics, Inc. Cooling device for removing heat from subcutaneous lipid-rich cells
KR101039758B1 (ko) 2006-04-28 2011-06-09 젤티크 애스세틱스, 인코포레이티드. 피하 지질 과다 세포의 개선된 냉각을 위한 치료 장치와함께 사용하기 위한 동결 방지제
US20070270925A1 (en) 2006-05-17 2007-11-22 Juniper Medical, Inc. Method and apparatus for non-invasively removing heat from subcutaneous lipid-rich cells including a coolant having a phase transition temperature
WO2008017456A1 (de) * 2006-08-07 2008-02-14 Fabian Temme Infusionssystem mit einem reaktionsgemisch zur temperaturveränderung einer infusionsflüssigkeit
US8192474B2 (en) 2006-09-26 2012-06-05 Zeltiq Aesthetics, Inc. Tissue treatment methods
US20080077201A1 (en) 2006-09-26 2008-03-27 Juniper Medical, Inc. Cooling devices with flexible sensors
US9132031B2 (en) 2006-09-26 2015-09-15 Zeltiq Aesthetics, Inc. Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile
WO2008055243A2 (en) 2006-10-31 2008-05-08 Zeltiq Aesthetics, Inc. Method and apparatus for cooling subcutaneous lipid-rich cells or tissue
US8057426B2 (en) * 2007-01-03 2011-11-15 Medtronic Vascular, Inc. Devices and methods for injection of multiple-component therapies
US20080287839A1 (en) 2007-05-18 2008-11-20 Juniper Medical, Inc. Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator
WO2008153789A1 (en) * 2007-05-29 2008-12-18 Van Lewis Injector and thermal jacket for use with same
US20090018624A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. Limiting use of disposable system patient protection devices
US20090018626A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. User interfaces for a system that removes heat from lipid-rich regions
US8523927B2 (en) 2007-07-13 2013-09-03 Zeltiq Aesthetics, Inc. System for treating lipid-rich regions
US20090018627A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. Secure systems for removing heat from lipid-rich regions
US20090018625A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. Managing system temperature to remove heat from lipid-rich regions
US9044212B2 (en) 2007-07-30 2015-06-02 Nuvue Therapeutics, Inc. Fluid flowing device and method for tissue diagnosis or therapy
EP2182898B1 (en) 2007-08-21 2018-10-03 Zeltiq Aesthetics, Inc. Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue
WO2009052470A2 (en) * 2007-10-19 2009-04-23 The Trustees Of The University Of Pennsylvania System and method for producing and determining cooling capacity of two-phase coolants
US8298216B2 (en) 2007-11-14 2012-10-30 Myoscience, Inc. Pain management using cryogenic remodeling
WO2009089090A2 (en) 2008-01-03 2009-07-16 Vertos Medical, Inc. Thermally regulated hypodermic needles, methods of use, and kits
US8505315B2 (en) * 2008-04-15 2013-08-13 Uchicago Argonne, Llc Enhanced integrated operation blender based sterile medical ice slurry production device
CN102143724B (zh) 2008-08-07 2015-02-25 通用医疗公司 用于皮肤病学色素减退的方法和装置
WO2010017556A1 (en) 2008-08-08 2010-02-11 Palomar Medical Technologies, Inc Method and apparatus for fractional deformation and treatment of cutaneous and subcutaneous tissue
EP2346428B1 (en) 2008-09-25 2019-11-06 Zeltiq Aesthetics, Inc. Treatment planning systems and methods for body contouring applications
US8414356B2 (en) 2008-10-31 2013-04-09 The Invention Science Fund I, Llc Systems, devices, and methods for making or administering frozen particles
US8603073B2 (en) 2008-12-17 2013-12-10 Zeltiq Aesthetics, Inc. Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells
JP5460735B2 (ja) * 2009-01-20 2014-04-02 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 低温容器
ES2533790T3 (es) * 2009-02-06 2015-04-14 Tecres S.P.A. Mezclador para compuestos bifásicos
US8608696B1 (en) 2009-02-24 2013-12-17 North Carolina State University Rapid fluid cooling devices and methods for cooling fluids
CN102596116B (zh) 2009-04-30 2015-01-14 斯尔替克美学股份有限公司 从皮下富脂细胞去除热量的装置、系统和方法
US20140200511A1 (en) 2009-10-30 2014-07-17 Searete Llc Systems, devices, and methods for making or administering frozen particles
WO2011091293A1 (en) 2010-01-21 2011-07-28 Zeltiq Aesthetics, Inc. Compositions for use with a system for improved cooling of subcutaneous lipid-rich tissue
US9844461B2 (en) 2010-01-25 2017-12-19 Zeltiq Aesthetics, Inc. Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants
WO2011100692A1 (en) 2010-02-15 2011-08-18 The General Hospital Corporation Methods and devices for selective disruption of visceral fat by controlled cooling
CN103210266A (zh) 2010-06-08 2013-07-17 纳诺艾斯公司 超小型冰及其用途以及用于生产的设备
US8676338B2 (en) 2010-07-20 2014-03-18 Zeltiq Aesthetics, Inc. Combined modality treatment systems, methods and apparatus for body contouring applications
KR101679467B1 (ko) 2010-08-19 2016-11-24 시네론 메디컬 리미티드 피부 미용 치료를 위한 개인용 전자기 에너지 애플리케이터
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US10722395B2 (en) 2011-01-25 2020-07-28 Zeltiq Aesthetics, Inc. Devices, application systems and methods with localized heat flux zones for removing heat from subcutaneous lipid-rich cells
EP2667811B1 (en) 2011-01-27 2015-12-30 Cryosa, Llc Apparatus for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
US8690934B2 (en) 2011-05-09 2014-04-08 The Invention Science Fund I, Llc Method, device and system for modulating an activity of brown adipose tissue in a vertebrate subject
JP6082864B2 (ja) 2011-08-09 2017-02-22 シネロン メディカル リミテッド 美容皮膚手入れの装置
US20130053792A1 (en) 2011-08-24 2013-02-28 Ablative Solutions, Inc. Expandable catheter system for vessel wall injection and muscle and nerve fiber ablation
US9056185B2 (en) 2011-08-24 2015-06-16 Ablative Solutions, Inc. Expandable catheter system for fluid injection into and deep to the wall of a blood vessel
KR102359731B1 (ko) 2011-11-16 2022-02-08 더 제너럴 하스피탈 코포레이션 피부 조직의 극저온 처리를 위한 방법 및 장치
CN116236338A (zh) 2011-11-16 2023-06-09 通用医疗公司 用于低温处理皮肤组织的方法和装置
ES2421545B1 (es) * 2012-02-01 2014-06-25 Universitat Polit�Cnica De Catalunya Dispositivo de dosificación e inyección de cementos óseos
IL219477A0 (en) 2012-04-30 2012-07-31 Berger Thermal Res Ltd A method for coupling between catheter tip and tissue by icing their interface and apparatus therefor
WO2013181667A1 (en) 2012-06-01 2013-12-05 Cibiem, Inc. Percutaneous methods and devices for carotid body ablation
US20140030697A1 (en) 2012-06-14 2014-01-30 Massachusetts Institute Of Technology Sortase-mediated modification of viral surface proteins
WO2014046552A1 (en) 2012-09-20 2014-03-27 Graham Brewster Ice slurry delivery system and components thereof
US9301795B2 (en) 2012-10-29 2016-04-05 Ablative Solutions, Inc. Transvascular catheter for extravascular delivery
EP3598952A3 (en) 2012-11-05 2020-04-15 Relievant Medsystems, Inc. Systems and methods for creating curved paths through bone and modulating nerves within the bone
US9114215B2 (en) 2013-03-13 2015-08-25 Bayer Medical Care Inc. Multiple compartment syringe
US9844460B2 (en) 2013-03-14 2017-12-19 Zeltiq Aesthetics, Inc. Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same
US9545523B2 (en) 2013-03-14 2017-01-17 Zeltiq Aesthetics, Inc. Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue
CN103110473A (zh) * 2013-03-17 2013-05-22 广州市绿乔生物科技有限公司 一种散寒除湿保健袋及其使用方法
CN105517603B (zh) * 2013-06-04 2019-12-24 尤尼特拉克特注射器控股有限公司 用于双腔室混合注射器的致动机构
WO2014197625A1 (en) 2013-06-05 2014-12-11 Metavention, Inc. Modulation of targeted nerve fibers
US10406021B2 (en) * 2013-08-05 2019-09-10 Yue Wu Method and system for producing and delivering airless medical ice slurry to induce hypothermia
ES2533781B1 (es) * 2013-10-10 2016-06-07 Universitat Politècnica De Catalunya Dispositivo de mezcla e inyección de cementos óseos
US9949652B2 (en) 2013-10-25 2018-04-24 Ablative Solutions, Inc. Apparatus for effective ablation and nerve sensing associated with denervation
WO2015117026A2 (en) 2014-01-31 2015-08-06 Zeltiq Aesthetics, Inc. Treating systems and methods for treating cellulite and providing other treatments
EP3119356B1 (en) 2014-03-21 2019-03-20 The University of Western Ontario Mammalian head cooling system
US9550028B2 (en) * 2014-05-06 2017-01-24 Biomet Biologics, LLC. Single step desiccating bead-in-syringe concentrating device
CN204050541U (zh) * 2014-06-30 2014-12-31 倪卫民 一种便携式麻醉注射器冷却装置
US10568759B2 (en) 2014-08-19 2020-02-25 Zeltiq Aesthetics, Inc. Treatment systems, small volume applicators, and methods for treating submental tissue
US10646666B2 (en) 2014-08-27 2020-05-12 Tva Medical, Inc. Cryolipolysis devices and methods therefor
BR112017003143B1 (pt) 2014-08-28 2023-12-05 The General Hospital Corporation Suspensões injetáveis, métodos para fabricação das mesmas e seus usos
GB2529867B (en) * 2014-09-04 2016-09-21 Ajibola Afolabi Oluwafemi Beverage cooling device
US20160089550A1 (en) 2014-09-25 2016-03-31 Zeltiq Aesthetics, Inc. Treatment systems, methods, and apparatuses for altering the appearance of skin
WO2016054165A1 (en) * 2014-10-01 2016-04-07 Novocor Medical Systems, Inc. Fluid cooling devices, systems and methods for cooling fluids
EP3200736B8 (en) 2014-10-01 2020-06-17 CryOSA, Inc. Apparatus for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
US10554404B2 (en) 2014-10-20 2020-02-04 Dspace Digital Signal Processing And Control Engineering Gmbh Protection of software models
CN105640706A (zh) * 2014-11-14 2016-06-08 湖北文理学院 冷敷创可贴
EP3226795B1 (en) 2014-12-03 2020-08-26 Metavention, Inc. Systems for modulating nerves or other tissue
EP3288626A4 (en) 2015-04-27 2019-01-23 Reflex Medical Inc. SYSTEMS AND METHODS FOR SYMPATHETIC CARDIO-PULMONARY NEUROMODULATION
EP3359100B1 (en) * 2015-10-05 2021-08-11 C° Change Surgical LLC Use of sterile sleeve in production of surgical slush
US11154418B2 (en) 2015-10-19 2021-10-26 Zeltiq Aesthetics, Inc. Vascular treatment systems, cooling devices, and methods for cooling vascular structures
CN205163644U (zh) * 2015-11-09 2016-04-20 广西壮族自治区人民医院 一种加压式冰冻输液袋
MX2018010220A (es) * 2016-02-26 2018-11-29 Massachusetts Gen Hospital Sistemas y metodos de produccion y suministro de suspension medica helada.
CN109310516A (zh) 2016-05-10 2019-02-05 斯尔替克美学股份有限公司 用于处理痤疮和皮肤状况的皮肤冷冻系统
US11382790B2 (en) 2016-05-10 2022-07-12 Zeltiq Aesthetics, Inc. Skin freezing systems for treating acne and skin conditions
MX2019005153A (es) * 2016-11-02 2019-11-12 J P Velis Christopher Dispositivos y métodos para la generación de una suspensión acuosa espesa.
US11324673B2 (en) * 2016-11-18 2022-05-10 Miraki Innovation Think Tank Llc Cosmetic appearance of skin
US10500342B2 (en) * 2017-08-21 2019-12-10 Miraki Innovation Think Tank Llc Cold slurry syringe
AU2019250128A1 (en) * 2018-10-15 2020-04-30 Avent Inc. Compositions, systems, kits, and methods for neural ablation
JP2020062408A (ja) * 2018-10-15 2020-04-23 アヴェント インコーポレイテッド 高周波アブレーション処置中に治療部位にポリマー材料を送達するためのシステム及び方法

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