BR112019004495B1 - Método para produção de um implante compreendendo pó compósito contendo carbonato de cálcio tendo partículas microestruturadas com inibição de carbonato de cálcio - Google Patents

Método para produção de um implante compreendendo pó compósito contendo carbonato de cálcio tendo partículas microestruturadas com inibição de carbonato de cálcio Download PDF

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Publication number
BR112019004495B1
BR112019004495B1 BR112019004495-7A BR112019004495A BR112019004495B1 BR 112019004495 B1 BR112019004495 B1 BR 112019004495B1 BR 112019004495 A BR112019004495 A BR 112019004495A BR 112019004495 B1 BR112019004495 B1 BR 112019004495B1
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BR
Brazil
Prior art keywords
particles
weight
calcium carbonate
composite powder
acid
Prior art date
Application number
BR112019004495-7A
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English (en)
Portuguese (pt)
Other versions
BR112019004495A2 (pt
Inventor
Frank Reinauer
Siegmund Luger
Marijan Vucak
Original Assignee
Karl Leibinger Medizintechnik Gmbh & Co. Kg
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Application filed by Karl Leibinger Medizintechnik Gmbh & Co. Kg filed Critical Karl Leibinger Medizintechnik Gmbh & Co. Kg
Publication of BR112019004495A2 publication Critical patent/BR112019004495A2/pt
Publication of BR112019004495B1 publication Critical patent/BR112019004495B1/pt

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    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09CTREATMENT OF INORGANIC MATERIALS, OTHER THAN FIBROUS FILLERS, TO ENHANCE THEIR PIGMENTING OR FILLING PROPERTIES ; PREPARATION OF CARBON BLACK  ; PREPARATION OF INORGANIC MATERIALS WHICH ARE NO SINGLE CHEMICAL COMPOUNDS AND WHICH ARE MAINLY USED AS PIGMENTS OR FILLERS
    • C09C1/00Treatment of specific inorganic materials other than fibrous fillers; Preparation of carbon black
    • C09C1/0081Composite particulate pigments or fillers, i.e. containing at least two solid phases, except those consisting of coated particles of one compound
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y70/00Materials specially adapted for additive manufacturing
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01FCOMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
    • C01F11/00Compounds of calcium, strontium, or barium
    • C01F11/18Carbonates
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01FCOMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
    • C01F11/00Compounds of calcium, strontium, or barium
    • C01F11/18Carbonates
    • C01F11/182Preparation of calcium carbonate by carbonation of aqueous solutions and characterised by an additive other than CaCO3-seeds
    • C01F11/183Preparation of calcium carbonate by carbonation of aqueous solutions and characterised by an additive other than CaCO3-seeds the additive being an organic compound
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/12Powdering or granulating
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/20Compounding polymers with additives, e.g. colouring
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09CTREATMENT OF INORGANIC MATERIALS, OTHER THAN FIBROUS FILLERS, TO ENHANCE THEIR PIGMENTING OR FILLING PROPERTIES ; PREPARATION OF CARBON BLACK  ; PREPARATION OF INORGANIC MATERIALS WHICH ARE NO SINGLE CHEMICAL COMPOUNDS AND WHICH ARE MAINLY USED AS PIGMENTS OR FILLERS
    • C09C1/00Treatment of specific inorganic materials other than fibrous fillers; Preparation of carbon black
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09CTREATMENT OF INORGANIC MATERIALS, OTHER THAN FIBROUS FILLERS, TO ENHANCE THEIR PIGMENTING OR FILLING PROPERTIES ; PREPARATION OF CARBON BLACK  ; PREPARATION OF INORGANIC MATERIALS WHICH ARE NO SINGLE CHEMICAL COMPOUNDS AND WHICH ARE MAINLY USED AS PIGMENTS OR FILLERS
    • C09C1/00Treatment of specific inorganic materials other than fibrous fillers; Preparation of carbon black
    • C09C1/02Compounds of alkaline earth metals or magnesium
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09CTREATMENT OF INORGANIC MATERIALS, OTHER THAN FIBROUS FILLERS, TO ENHANCE THEIR PIGMENTING OR FILLING PROPERTIES ; PREPARATION OF CARBON BLACK  ; PREPARATION OF INORGANIC MATERIALS WHICH ARE NO SINGLE CHEMICAL COMPOUNDS AND WHICH ARE MAINLY USED AS PIGMENTS OR FILLERS
    • C09C1/00Treatment of specific inorganic materials other than fibrous fillers; Preparation of carbon black
    • C09C1/02Compounds of alkaline earth metals or magnesium
    • C09C1/021Calcium carbonates
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00Particle morphology
    • C01P2004/01Particle morphology depicted by an image
    • C01P2004/03Particle morphology depicted by an image obtained by SEM
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00Particle morphology
    • C01P2004/30Particle morphology extending in three dimensions
    • C01P2004/32Spheres
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00Particle morphology
    • C01P2004/60Particles characterised by their size
    • C01P2004/61Micrometer sized, i.e. from 1-100 micrometer
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00Particle morphology
    • C01P2004/60Particles characterised by their size
    • C01P2004/62Submicrometer sized, i.e. from 0.1-1 micrometer

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Composite Materials (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Geology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Manufacturing & Machinery (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)
  • Biological Depolymerization Polymers (AREA)
BR112019004495-7A 2016-09-08 2017-08-17 Método para produção de um implante compreendendo pó compósito contendo carbonato de cálcio tendo partículas microestruturadas com inibição de carbonato de cálcio BR112019004495B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16187901 2016-09-08
EP16187901.0 2016-09-08
PCT/EP2017/070858 WO2018046274A1 (de) 2016-09-08 2017-08-17 Verfahren zur herstellung eines implantates umfassend calciumcarbonat-enthaltendes verbundpulver mit mikrostrukturierten teilchen mit inhibierendem calciumcarbonat

Publications (2)

Publication Number Publication Date
BR112019004495A2 BR112019004495A2 (pt) 2019-05-28
BR112019004495B1 true BR112019004495B1 (pt) 2022-05-24

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019004495-7A BR112019004495B1 (pt) 2016-09-08 2017-08-17 Método para produção de um implante compreendendo pó compósito contendo carbonato de cálcio tendo partículas microestruturadas com inibição de carbonato de cálcio

Country Status (10)

Country Link
US (1) US11124654B2 (zh)
EP (1) EP3509656B1 (zh)
JP (1) JP6980765B2 (zh)
CN (1) CN109689122B (zh)
AU (1) AU2017324192B2 (zh)
BR (1) BR112019004495B1 (zh)
CA (1) CA3035622A1 (zh)
ES (1) ES2823184T3 (zh)
RU (1) RU2743294C2 (zh)
WO (1) WO2018046274A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021118589A1 (en) * 2019-12-13 2021-06-17 Hewlett-Packard Development Company, L.P. Three-dimensional printing with calcium carbonate particles
JP7137227B2 (ja) * 2020-02-25 2022-09-14 株式会社micro-AMS 予備成形装置及び予備成形方法、並びに樹脂成形システム及び樹脂成形方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
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US4448845A (en) * 1982-09-29 1984-05-15 The Dow Chemical Company Halogenated polar polymer treatment of inorganic fillers
JPS6283029A (ja) 1985-10-07 1987-04-16 Nara Kikai Seisakusho:Kk 固体粒子の表面改質方法
US5043017A (en) * 1990-03-09 1991-08-27 Pfizer Inc. Acid-stabilized calcium carbonate, process for its production and method for its use in the manufacture of acidic paper
JPH06114099A (ja) 1991-06-12 1994-04-26 Nara Kikai Seisakusho:Kk 医用材料とその製造方法
JPH0751288B2 (ja) 1991-12-25 1995-06-05 株式会社奈良機械製作所 粒子の複合化方法
JP3390863B2 (ja) 1997-12-01 2003-03-31 株式会社奈良機械製作所 複合固体粒子とその製造方法
CA2401421A1 (en) 2000-03-03 2001-09-13 Smith & Nephew, Inc. Shaped particle and composition for bone deficiency and method of making the particle
DE602005013262D1 (de) * 2004-10-29 2009-04-23 Smith & Nephew Inc Bioabsorbierbare polymere mit kalziumkarbonat
EP1764347A1 (en) 2005-09-16 2007-03-21 Omya Development Ag Process of manufacturing a co-ground calcium carbonate material of the GCC and PCC type with a specific steepness factor, obtained products and their uses
DE102007018975A1 (de) 2007-04-07 2008-10-09 Schaefer Kalk Gmbh & Co. Kg Kugelförmige Calciumcarbonat-Teilchen
PT2264108E (pt) 2009-06-15 2012-05-23 Omya Development Ag Processo para preparar um carbonato de cálcio feito reagir em superfície utilizando um ácido fraco
CA2806131C (en) * 2010-07-30 2019-09-03 Schaefer Kalk Gmbh & Co. Kg Spherical, amorphous calcium carbonate particles
JP5724104B2 (ja) * 2010-11-30 2015-05-27 株式会社白石中央研究所 樹脂組成物
CN102247624A (zh) * 2011-01-21 2011-11-23 北京中奥汇成生物材料科技有限公司 一种可吸收骨螺钉及其制备方法
US9707734B2 (en) * 2011-03-18 2017-07-18 Schaefer Kalk Gmbh & Co. Kg Microstructured composite particles
PT2644568T (pt) 2012-03-30 2017-03-03 Omya Int Ag Material contendo carbonato de cálcio disperso para uma estabilidade melhorada sob condições alcalinas
RU148729U1 (ru) 2014-09-24 2014-12-10 Федеральное государственное бюджетное учреждение "Саратовский научно-исследовательский институт травматологии и ортопедии" Министерства здравоохранения Российской Федерации (ФГБУ "СарНИИТО" Минздрава России) Имплантат для хирургического лечения дефектов костной и хрящевой тканей
EP3045503A1 (en) * 2015-01-15 2016-07-20 Omya International AG Surface-treated calcium carbonate with improved stability in environments with a pH of 4.5 to 7

Also Published As

Publication number Publication date
EP3509656A1 (de) 2019-07-17
BR112019004495A2 (pt) 2019-05-28
US11124654B2 (en) 2021-09-21
WO2018046274A1 (de) 2018-03-15
RU2019109706A (ru) 2020-10-02
CN109689122A (zh) 2019-04-26
EP3509656B1 (de) 2020-07-22
RU2019109706A3 (zh) 2020-10-22
JP2019531927A (ja) 2019-11-07
CN109689122B (zh) 2021-12-03
AU2017324192B2 (en) 2021-11-25
US20190194468A1 (en) 2019-06-27
ES2823184T3 (es) 2021-05-06
CA3035622A1 (en) 2018-03-15
AU2017324192A1 (en) 2019-04-04
RU2743294C2 (ru) 2021-02-16
JP6980765B2 (ja) 2021-12-15

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