BR112019000251A2 - prevenção e tratamento de fibrilação/flutter atrial com sequestrantes de gama-cetoaldeído - Google Patents
prevenção e tratamento de fibrilação/flutter atrial com sequestrantes de gama-cetoaldeídoInfo
- Publication number
- BR112019000251A2 BR112019000251A2 BR112019000251-0A BR112019000251A BR112019000251A2 BR 112019000251 A2 BR112019000251 A2 BR 112019000251A2 BR 112019000251 A BR112019000251 A BR 112019000251A BR 112019000251 A2 BR112019000251 A2 BR 112019000251A2
- Authority
- BR
- Brazil
- Prior art keywords
- ketoaldehyde
- sequestrants
- gamma
- atrial fibrillation
- flutter
- Prior art date
Links
- 206010003658 Atrial Fibrillation Diseases 0.000 title abstract 2
- 239000003352 sequestering agent Substances 0.000 title abstract 2
- 206010003662 Atrial flutter Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4415—Pyridoxine, i.e. Vitamin B6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662359705P | 2016-07-07 | 2016-07-07 | |
| US62/359,705 | 2016-07-07 | ||
| PCT/US2017/041211 WO2018009875A1 (en) | 2016-07-07 | 2017-07-07 | Prevention and treatment of atrial fibrillation/flutter with gamma-ketoaldehyde scavengers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112019000251A2 true BR112019000251A2 (pt) | 2019-04-16 |
Family
ID=60913210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112019000251-0A BR112019000251A2 (pt) | 2016-07-07 | 2017-07-07 | prevenção e tratamento de fibrilação/flutter atrial com sequestrantes de gama-cetoaldeído |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20190247375A1 (https=) |
| EP (1) | EP3481505B1 (https=) |
| JP (1) | JP7179353B2 (https=) |
| CN (1) | CN110022936A (https=) |
| AU (1) | AU2017293950B2 (https=) |
| BR (1) | BR112019000251A2 (https=) |
| CA (1) | CA3030149A1 (https=) |
| ES (1) | ES3040735T3 (https=) |
| MX (1) | MX393913B (https=) |
| PL (1) | PL3481505T3 (https=) |
| WO (1) | WO2018009875A1 (https=) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6620836B1 (en) * | 1997-01-22 | 2003-09-16 | Jay Patrick | Antiarrhythmic and tranquilizer composition and treatment |
| US8822542B2 (en) * | 2004-10-20 | 2014-09-02 | Vanderbilt University | Isoketal scavengers and mitigation of disorders involving oxidative injury |
| US20070249562A1 (en) | 2006-04-25 | 2007-10-25 | Friesen Albert D | Treatment of atrial fibrillation |
| EP2477594A4 (en) * | 2009-07-15 | 2013-03-13 | Univ Vanderbilt | ISOKETAL CATCHER AND TREATMENT OF DISEASES WITH OXIDATIVE INJURY |
| US10975033B2 (en) * | 2011-07-12 | 2021-04-13 | Vanderbilt University | Methods for treating inflammation and hypertension with γ-ketoaldehyde skavengers |
-
2017
- 2017-07-07 CA CA3030149A patent/CA3030149A1/en active Pending
- 2017-07-07 EP EP17825031.2A patent/EP3481505B1/en active Active
- 2017-07-07 WO PCT/US2017/041211 patent/WO2018009875A1/en not_active Ceased
- 2017-07-07 CN CN201780054986.2A patent/CN110022936A/zh active Pending
- 2017-07-07 ES ES17825031T patent/ES3040735T3/es active Active
- 2017-07-07 BR BR112019000251-0A patent/BR112019000251A2/pt not_active Application Discontinuation
- 2017-07-07 AU AU2017293950A patent/AU2017293950B2/en active Active
- 2017-07-07 JP JP2019500259A patent/JP7179353B2/ja active Active
- 2017-07-07 PL PL17825031.2T patent/PL3481505T3/pl unknown
- 2017-07-07 US US16/314,852 patent/US20190247375A1/en not_active Abandoned
- 2017-07-07 MX MX2019000120A patent/MX393913B/es unknown
-
2024
- 2024-01-16 US US18/414,316 patent/US20240189291A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3481505B1 (en) | 2025-09-03 |
| PL3481505T3 (pl) | 2026-01-26 |
| MX2019000120A (es) | 2019-04-01 |
| AU2017293950B2 (en) | 2023-06-15 |
| JP2019520389A (ja) | 2019-07-18 |
| WO2018009875A1 (en) | 2018-01-11 |
| AU2017293950A1 (en) | 2019-01-31 |
| CA3030149A1 (en) | 2018-01-11 |
| MX393913B (es) | 2025-03-24 |
| EP3481505A1 (en) | 2019-05-15 |
| JP7179353B2 (ja) | 2022-11-29 |
| US20240189291A1 (en) | 2024-06-13 |
| EP3481505C0 (en) | 2025-09-03 |
| US20190247375A1 (en) | 2019-08-15 |
| CN110022936A (zh) | 2019-07-16 |
| ES3040735T3 (en) | 2025-11-04 |
| EP3481505A4 (en) | 2020-02-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B12B | Appeal against refusal [chapter 12.2 patent gazette] |