BR112018075395A2 - combinação de reguladores metabólicos bioenergé-ticos e nutra-epigenéticos, compostos nutracêuti-cos em combinações convencionais e baseadas em na-notecnologia para reverter e prevenir a senescên-cia celular acelerada por lesão crônica causada por diabetes e outras doenças complexas crônico-degenerativas - Google Patents
combinação de reguladores metabólicos bioenergé-ticos e nutra-epigenéticos, compostos nutracêuti-cos em combinações convencionais e baseadas em na-notecnologia para reverter e prevenir a senescên-cia celular acelerada por lesão crônica causada por diabetes e outras doenças complexas crônico-degenerativasInfo
- Publication number
- BR112018075395A2 BR112018075395A2 BR112018075395-5A BR112018075395A BR112018075395A2 BR 112018075395 A2 BR112018075395 A2 BR 112018075395A2 BR 112018075395 A BR112018075395 A BR 112018075395A BR 112018075395 A2 BR112018075395 A2 BR 112018075395A2
- Authority
- BR
- Brazil
- Prior art keywords
- chronic
- diabetes
- nutra
- bioenergetic
- epigenetic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562172339P | 2015-06-08 | 2015-06-08 | |
| US15/176,422 US10285963B2 (en) | 2015-06-08 | 2016-06-08 | Combination of metabolic bio-energetic and nutra-epigentic regulators, nutraceutical compounds in conventional and nanotechnologies combination to revert and prevent the chronic damage accelerated cellular senescence produced by diabetes and other degenerative chronic complex diseases |
| US15/176,422 | 2016-06-08 | ||
| MX2017007448A MX365886B (es) | 2015-06-08 | 2017-06-07 | Combinación de reguladores metabólicos bioenergéticos y nutra-epigenéticos, compuestos nutracéuticos en combinaciones convencionales y nanotecnológicas para revertir y prevenir la senescencia celular acelerada por daño crónico producida por diabetes y otras enfermedades complejas crónico-degenerativas. |
| MXMX/A/2017/007448 | 2017-06-07 | ||
| PCT/MX2017/000061 WO2017213486A2 (es) | 2016-06-08 | 2017-06-08 | Combinación de reguladores metabólicos bioenergéticos y nutra-epigenéticos, compuestos nutracéuticos en combinaciónes convencionales y nanotecnológicas para revertir y prevenir la sesencencia celular acelerada por daño crónico producida por diabetes y otras enfermedades complejas crónico-degenerativas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112018075395A2 true BR112018075395A2 (pt) | 2019-04-02 |
Family
ID=57450744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112018075395-5A BR112018075395A2 (pt) | 2015-06-08 | 2017-06-08 | combinação de reguladores metabólicos bioenergé-ticos e nutra-epigenéticos, compostos nutracêuti-cos em combinações convencionais e baseadas em na-notecnologia para reverter e prevenir a senescên-cia celular acelerada por lesão crônica causada por diabetes e outras doenças complexas crônico-degenerativas |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10285963B2 (enExample) |
| JP (1) | JP2019521184A (enExample) |
| CN (1) | CN109890369B (enExample) |
| BR (1) | BR112018075395A2 (enExample) |
| CA (1) | CA3027048A1 (enExample) |
| ES (1) | ES2988151T3 (enExample) |
| MX (1) | MX365886B (enExample) |
| RU (1) | RU2749950C2 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3470060B1 (en) * | 2016-06-08 | 2024-07-31 | Astudillo De La Vega, Horacio | Composition comprising resveratrol, glycine, arginine and cysteine for use in treating metabolic syndrome |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006273834A (ja) * | 2004-06-28 | 2006-10-12 | Kao Corp | Ampk活性化剤 |
| US7709539B2 (en) * | 2004-08-11 | 2010-05-04 | Chang Gung University | Therapeutic use of resveratrol for hyperglycemia |
| ITPD20050224A1 (it) * | 2005-07-19 | 2007-01-20 | Actimex Srl | Composizioni contenenti micronutrienti aventi in particolare attivita' antiossidante e loro impiego |
| US20100209382A1 (en) * | 2005-09-16 | 2010-08-19 | Ordway Research Institute, Inc. | Polyphenol Conjugates as RGD-Binding Compounds and Methods of Use |
| WO2008143182A1 (ja) * | 2007-05-17 | 2008-11-27 | Kaneka Corporation | 甘草ポリフェノールを含有する組成物 |
| JP5594819B2 (ja) * | 2009-12-22 | 2014-09-24 | キリンホールディングス株式会社 | 脂質代謝改善用組成物 |
| JP2012041296A (ja) * | 2010-08-19 | 2012-03-01 | Medience Corp | 血管内皮機能改善剤、一酸化窒素産生促進剤、及び飲食品 |
| RU2017129378A (ru) * | 2011-07-15 | 2019-02-04 | Нусерт Сайенсиз, Инк. | Композиции и способы модулирования метаболических путей |
-
2016
- 2016-06-08 US US15/176,422 patent/US10285963B2/en active Active
-
2017
- 2017-06-07 MX MX2017007448A patent/MX365886B/es active IP Right Grant
- 2017-06-08 CA CA3027048A patent/CA3027048A1/en active Pending
- 2017-06-08 CN CN201780046806.6A patent/CN109890369B/zh active Active
- 2017-06-08 ES ES17810608T patent/ES2988151T3/es active Active
- 2017-06-08 BR BR112018075395-5A patent/BR112018075395A2/pt not_active Application Discontinuation
- 2017-06-08 JP JP2019517750A patent/JP2019521184A/ja active Pending
- 2017-06-08 RU RU2018147077A patent/RU2749950C2/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| CA3027048A1 (en) | 2017-12-14 |
| JP2019521184A (ja) | 2019-07-25 |
| CN109890369A (zh) | 2019-06-14 |
| CN109890369B (zh) | 2022-04-29 |
| RU2018147077A3 (enExample) | 2020-09-21 |
| MX365886B (es) | 2019-06-19 |
| MX2017007448A (es) | 2018-09-10 |
| ES2988151T3 (es) | 2024-11-19 |
| US20160354331A1 (en) | 2016-12-08 |
| RU2018147077A (ru) | 2020-07-10 |
| US10285963B2 (en) | 2019-05-14 |
| RU2749950C2 (ru) | 2021-06-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Martínez-Ceron et al. | Effects of continuous positive airway pressure treatment on glucose metabolism in patients with obstructive sleep apnea | |
| Sulaiman et al. | Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy | |
| Jiang et al. | Butyrate improves cardiac function and sympathetic neural remodeling following myocardial infarction in rats | |
| Sun et al. | Gut microbial metabolite TMAO contributes to renal dysfunction in a mouse model of diet-induced obesity | |
| Pereira et al. | OPA 1 deficiency promotes secretion of FGF 21 from muscle that prevents obesity and insulin resistance | |
| Rochette et al. | Diabetes, oxidative stress and therapeutic strategies | |
| Yan et al. | The roles and pharmacological effects of FGF21 in preventing aging-associated metabolic diseases | |
| Li et al. | Sestrin 2 induces autophagy and attenuates insulin resistance by regulating AMPK signaling in C2C12 myotubes | |
| BR112015010203A8 (pt) | composição para a prevenção ou tratamento de diabetes, complicações diabéticas ou diabesidade, uso de um conjugado análogo da oxintomodulina, e, método para a preparação de um conjugado análogo da oxintomodulina | |
| Su et al. | Mitophagy in hepatic insulin resistance: therapeutic potential and concerns | |
| Argilés et al. | Muscle wasting in cancer: the role of mitochondria | |
| Zhabyeyev et al. | Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload | |
| Hu et al. | Metformin and berberine prevent olanzapine-induced weight gain in rats | |
| Tang et al. | Sitagliptin inhibits endothelin-1 expression in the aortic endothelium of rats with streptozotocin-induced diabetes by suppressing the nuclear factor-κB/IκBα system through the activation of AMP-activated protein kinase | |
| Bezerra et al. | Caffeic acid phenethyl ester reduces the activation of the nuclear factor κB pathway by high-fat diet-induced obesity in mice | |
| Marette et al. | Skeletal muscle glucose metabolism and inflammation in the development of the metabolic syndrome | |
| Yang et al. | Alpha-lipoic acid attenuates insulin resistance and improves glucose metabolism in high fat diet-fed mice | |
| Totsch et al. | Effects of a Standard American Diet and an anti‐inflammatory diet in male and female mice | |
| Zheng et al. | Anhydroicaritin, a SREBPs inhibitor, inhibits RANKL-induced osteoclastic differentiation and improves diabetic osteoporosis in STZ-induced mice | |
| BR112013010021A2 (pt) | combinações farmacêuticas para o tratamento de distúrbios metabólicos. | |
| Xu et al. | Hypoglycemic and hypolipidemic effects of triterpenoid-enriched Jamun (Eugenia jambolana Lam.) fruit extract in streptozotocin-induced type 1 diabetic mice | |
| Kusunoki et al. | Black soybean extract improves lipid profiles in fenofibrate-treated type 2 diabetics with postprandial hyperlipidemia | |
| Rolland et al. | Therapeutic prospects of PPARs in psychiatric disorders: a comprehensive review | |
| Marin et al. | Oestrogens as M odulators of N euronal Si gnalosomes and B rain L ipid H omeostasis R elated to P rotection A gainst N eurodegeneration | |
| Bu et al. | Blocking central galanin receptors attenuates insulin sensitivity in myocytes of diabetic trained rats |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |