BR112018068456A2 - aminoácido ou peptídeo n-lipoico, derivados e seus usos - Google Patents
aminoácido ou peptídeo n-lipoico, derivados e seus usosInfo
- Publication number
- BR112018068456A2 BR112018068456A2 BR112018068456A BR112018068456A BR112018068456A2 BR 112018068456 A2 BR112018068456 A2 BR 112018068456A2 BR 112018068456 A BR112018068456 A BR 112018068456A BR 112018068456 A BR112018068456 A BR 112018068456A BR 112018068456 A2 BR112018068456 A2 BR 112018068456A2
- Authority
- BR
- Brazil
- Prior art keywords
- amino acid
- derivatives
- lipoic
- compositions
- peptide
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 4
- 239000002537 cosmetic Substances 0.000 abstract 2
- -1 amino acid compounds Chemical class 0.000 abstract 1
- 210000005093 cutaneous system Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 230000002087 whitening effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Birds (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Immunology (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
são descritos novos compostos de aminoácido n-lipoico, peptídeos n-lipoicos, e seus derivados. são também descritas composições e métodos de composições contendo os derivados dos aminoácidos ou peptídeos, e seus usos incluindo tratamento e prevenção de condições dermatológicas ou cosméticas ou outros distúrbios do sistema cutâneo. são também revelados composições e métodos para uso das composições para clareamento de pele e cosméticos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2016/022289 WO2017160269A1 (en) | 2016-03-14 | 2016-03-14 | N-lipoic -amino acid or peptide, derivatives and their uses |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112018068456A2 true BR112018068456A2 (pt) | 2019-01-22 |
Family
ID=59850403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018068456A BR112018068456A2 (pt) | 2016-03-14 | 2016-03-14 | aminoácido ou peptídeo n-lipoico, derivados e seus usos |
Country Status (13)
Country | Link |
---|---|
US (1) | US11155531B2 (pt) |
EP (2) | EP3429577B1 (pt) |
JP (1) | JP6858837B2 (pt) |
KR (1) | KR102626973B1 (pt) |
CN (1) | CN109152757A (pt) |
AU (1) | AU2016397562B2 (pt) |
BR (1) | BR112018068456A2 (pt) |
CA (1) | CA3017449C (pt) |
DK (1) | DK3429577T3 (pt) |
ES (1) | ES2906178T3 (pt) |
MX (1) | MX2018011082A (pt) |
RU (1) | RU2737377C2 (pt) |
WO (1) | WO2017160269A1 (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023283256A1 (en) | 2021-07-09 | 2023-01-12 | Aligos Therapeutics, Inc. | Anti-viral compounds |
KR102404228B1 (ko) * | 2022-02-18 | 2022-05-31 | 주식회사 차메디텍 | 항산화 효과를 증대시키는 환원된 리포익산-펩타이드 유도체를 포함하는 조성물 및 이의 제조 방법 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63107071A (ja) * | 1986-10-23 | 1988-05-12 | Nec Corp | 電界効果トランジスタの製造方法 |
JPH11269170A (ja) * | 1997-04-02 | 1999-10-05 | Sankyo Co Ltd | ジチオラン誘導体 |
CZ96798A3 (cs) * | 1997-04-02 | 1998-10-14 | Sankyo Company Limited | Deriváty dithiolanu, jejich příprava a jejich terapeutické účinky |
US6664287B2 (en) * | 2000-03-15 | 2003-12-16 | Bethesda Pharmaceuticals, Inc. | Antioxidants |
AU2001270554A1 (en) * | 2000-06-06 | 2001-12-17 | Basf Aktiengesellschaft | Use of an (r)-enantiomer of lipoic acid in cosmetics and dermatologicals |
JP4259813B2 (ja) * | 2001-05-29 | 2009-04-30 | 千寿製薬株式会社 | α−リポイルアミノ酸の安定化法および安定化されたα−リポイルアミノ酸を含有する水性液剤 |
JP2003286168A (ja) * | 2002-03-28 | 2003-10-07 | Senju Pharmaceut Co Ltd | α−リポイルアミノ酸を含有する皮膚外用剤 |
WO2003084532A1 (en) * | 2002-04-03 | 2003-10-16 | Avery Mitchell A | Lipoic acid analogs useful as provitamins and antioxidants |
FR2870244B1 (fr) * | 2004-05-11 | 2011-01-07 | Centre Nat Rech Scient | Conjugues dipeptidiques antagonistes de l'alpha-msh |
FR2870242B1 (fr) * | 2004-05-11 | 2010-08-20 | Inst Europeen Biologie Cellulaire | Peptides ou conjugues peptidiques derives de la msh et leur utilisation dans le traitement cosmetique de la canitie. |
JP2006022066A (ja) * | 2004-07-09 | 2006-01-26 | Shiseido Co Ltd | 重合抑制剤および即時型黒化防止用皮膚外用剤 |
US7776915B2 (en) * | 2005-03-24 | 2010-08-17 | Tracie Martyn International, Llc | Topical formulations and methods of use |
GB0605295D0 (en) * | 2006-03-16 | 2006-04-26 | Proximagen Ltd | Amino and derivatives |
US20100310484A1 (en) * | 2007-06-29 | 2010-12-09 | Innovactiv Inc. | Novel peptides, use thereof in cosmetic and cosmeceutic applications, and compositions comprising same |
US20100255109A1 (en) * | 2007-08-06 | 2010-10-07 | Biogenics, Inc. | Stabilized antioxidant particles, composition comprising the same and method for preparing the same |
WO2010045575A2 (en) * | 2008-10-17 | 2010-04-22 | Invasc Therapeutics, Inc. | Compositions and methods for treatment of renin-angiotensin aldosterone system (raas)-related disorders |
US8946451B2 (en) * | 2009-10-05 | 2015-02-03 | Catabasis Pharmaceuticals, Inc. | Lipoic acid acylated salicylate derivatives and their uses |
JP2011195516A (ja) * | 2010-03-19 | 2011-10-06 | Oita Univ | 制がん剤 |
ES2640474T3 (es) * | 2010-11-18 | 2017-11-03 | Ischemix Llc | Compuestos lipoílicos y su uso para el tratamiento de la lesión isquémica |
DK3415157T3 (da) * | 2011-10-28 | 2020-10-19 | Neostrata Company Inc | N-acyldipeptidderivater og anvendelser deraf |
US20150329519A1 (en) * | 2014-05-14 | 2015-11-19 | Ischemix, LLC | Formulations Comprising Lipoyl Compounds |
JP6271346B2 (ja) | 2014-06-12 | 2018-01-31 | アトムメディカル株式会社 | ガス類供給用マスク装置 |
-
2016
- 2016-03-14 DK DK16894728.1T patent/DK3429577T3/da active
- 2016-03-14 EP EP16894728.1A patent/EP3429577B1/en active Active
- 2016-03-14 WO PCT/US2016/022289 patent/WO2017160269A1/en active Application Filing
- 2016-03-14 JP JP2019500210A patent/JP6858837B2/ja active Active
- 2016-03-14 MX MX2018011082A patent/MX2018011082A/es unknown
- 2016-03-14 BR BR112018068456A patent/BR112018068456A2/pt active Search and Examination
- 2016-03-14 CA CA3017449A patent/CA3017449C/en active Active
- 2016-03-14 KR KR1020187029592A patent/KR102626973B1/ko active IP Right Grant
- 2016-03-14 ES ES16894728T patent/ES2906178T3/es active Active
- 2016-03-14 US US16/083,924 patent/US11155531B2/en active Active
- 2016-03-14 AU AU2016397562A patent/AU2016397562B2/en active Active
- 2016-03-14 CN CN201680083621.8A patent/CN109152757A/zh active Pending
- 2016-03-14 RU RU2018136108A patent/RU2737377C2/ru active
- 2016-03-14 EP EP21217352.0A patent/EP4018997A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2019508506A (ja) | 2019-03-28 |
KR20180120769A (ko) | 2018-11-06 |
CA3017449A1 (en) | 2017-09-21 |
EP3429577A4 (en) | 2019-11-06 |
WO2017160269A1 (en) | 2017-09-21 |
AU2016397562B2 (en) | 2023-06-29 |
US11155531B2 (en) | 2021-10-26 |
JP6858837B2 (ja) | 2021-04-14 |
CN109152757A (zh) | 2019-01-04 |
RU2018136108A (ru) | 2020-04-15 |
US20190161467A1 (en) | 2019-05-30 |
MX2018011082A (es) | 2019-03-28 |
EP3429577B1 (en) | 2021-12-29 |
ES2906178T3 (es) | 2022-04-13 |
EP4018997A1 (en) | 2022-06-29 |
AU2016397562A1 (en) | 2018-09-27 |
DK3429577T3 (da) | 2022-03-07 |
RU2018136108A3 (pt) | 2020-04-15 |
CA3017449C (en) | 2023-09-19 |
RU2737377C2 (ru) | 2020-11-27 |
KR102626973B1 (ko) | 2024-01-22 |
EP3429577A1 (en) | 2019-01-23 |
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Legal Events
Date | Code | Title | Description |
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] |