BR112018015523A2 - sistema de ensaio microfluídico, cartucho microfluídico, e, método para realizar um ensaio. - Google Patents

sistema de ensaio microfluídico, cartucho microfluídico, e, método para realizar um ensaio.

Info

Publication number
BR112018015523A2
BR112018015523A2 BR112018015523A BR112018015523A BR112018015523A2 BR 112018015523 A2 BR112018015523 A2 BR 112018015523A2 BR 112018015523 A BR112018015523 A BR 112018015523A BR 112018015523 A BR112018015523 A BR 112018015523A BR 112018015523 A2 BR112018015523 A2 BR 112018015523A2
Authority
BR
Brazil
Prior art keywords
microfluidic
blade
microfluidic cartridge
flow channel
section
Prior art date
Application number
BR112018015523A
Other languages
English (en)
Other versions
BR112018015523B1 (pt
Inventor
Overby Bent
Kristian BAU-MADSEN Niels
Original Assignee
Scandinavian Micro Biodevices Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scandinavian Micro Biodevices Aps filed Critical Scandinavian Micro Biodevices Aps
Publication of BR112018015523A2 publication Critical patent/BR112018015523A2/pt
Publication of BR112018015523B1 publication Critical patent/BR112018015523B1/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6482—Sample cells, cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6484—Optical fibres

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

sistema de ensaio microfluídico incluindo um cartucho microfluídico e um sistema operador microfluídico associado. o cartucho microfluídico compreende uma parte de base tendo uma primeira face com um rebaixo e uma lâmina fixada à parte de base para cobrir o rebaixo e fornecer uma face de lâmina de cartucho microfluídico. a parte de base com o rebaixo e a lâmina forma um canal de fluxo e um depósito em comunicação fluida um com os outro. o cartucho microfluídico compreende uma abertura de entrada no canal de fluxo à montante da seção de reação. o sistema operador inclui um pistão, um elemento de regulagem de temperatura e um atuador posicionado tal que a face da lâmina do cartucho microfluídico possa ser posicionado em contato com o sistema operativo com a seção de reação em proximidade ao elemento de regulagem de temperatura enquanto o atuador é associado à seção de depósito para pressionar a lâmina cobrindo a seção de depósito e o pistão sendo associado ao canal de fluxo em uma seção de válvula à montante para pressionar a lâmina para fechar o canal de fluxo à montante da seção de reação.
BR112018015523-3A 2016-02-01 2017-01-31 Sistema de ensaio microfluídico, e, método para realizar um ensaio BR112018015523B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201670055 2016-02-01
DKPA201670055 2016-02-01
PCT/DK2017/050020 WO2017133741A1 (en) 2016-02-01 2017-01-31 A microfluidic assay system, a microfluidic cartridge and a method of performing an assay

Publications (2)

Publication Number Publication Date
BR112018015523A2 true BR112018015523A2 (pt) 2018-12-26
BR112018015523B1 BR112018015523B1 (pt) 2023-06-20

Family

ID=

Also Published As

Publication number Publication date
PT3411151T (pt) 2021-08-03
KR20180105225A (ko) 2018-09-27
TWI789343B (zh) 2023-01-11
MX2018009250A (es) 2018-09-10
CN108698046B (zh) 2021-10-22
US11400449B2 (en) 2022-08-02
CA3013085A1 (en) 2017-08-10
ES2881342T3 (es) 2021-11-29
CN108698046A (zh) 2018-10-23
EP3411151B1 (en) 2021-06-16
DK3411151T3 (da) 2021-07-26
EP3411151A4 (en) 2019-08-28
JP6938517B2 (ja) 2021-09-22
EP3411151A1 (en) 2018-12-12
WO2017133741A1 (en) 2017-08-10
US20210187501A1 (en) 2021-06-24
AU2017214175A1 (en) 2018-07-19
NZ744129A (en) 2021-03-26
TW201728894A (zh) 2017-08-16
AU2017214175B2 (en) 2021-09-23
JP2019508687A (ja) 2019-03-28
PL3411151T3 (pl) 2021-12-06
CA3013085C (en) 2024-01-02

Similar Documents

Publication Publication Date Title
MX2018009250A (es) Un sistema de ensayo de microfluido, un cartucho de microfluido y un metodo para ejecutar un ensayo.
BR112018074004A2 (pt) recursos e métodos para controlar a aplicação de fluido de resfriamento ao atuador de extremidade de instrumento cirúrgico ultrassônico
BR112018070030A2 (pt) cartucho de aparelho de barbear ou depilar com sistema de gerenciamento de fluidos
BR112016027939B8 (pt) Sistemas e métodos incluindo uma válvula rotativa para pelo menos um entre preparação de amostra ou análise de amostra
BR112016028064A2 (pt) Conjunto de válvula e dispositivo de spray de aerossol
BR112012026131A2 (pt) aparelho e método para controlar seletivamente o fluxo.
NO20171662A1 (en) Shearing gate valve system
BR112017023457A2 (pt) ?sistema de segurança de preventor de blowout, método para testar a integridade de válvulas de segurança e sistema de caracterização de segurança de bop?
BR112019024821A2 (pt) teste de integridade de pressão de conjunto de completação de único trajeto
BR112015020440A2 (pt) válvula de controle com recuperação de energia
DK3692291T3 (da) Ventil og reservoir(er) til fluid under tryk
BR112015016726A2 (pt) válvulas borboleta tendo múltiplas vedações
BR112018008240A2 (pt) válvula de controle de fluido
BR112017003493A2 (pt) dispositivo de injeção, e, método para injetar um fluido.
BR112016002184A2 (pt) melhorias em servoválvulas hidráulicas
BR112015021358A2 (pt) conjunto de válvula, sistema de perfuração, e, qualquer nova funcionalidade ou nova combinação
BR112017009417A2 (pt) válvula de descompressão para o controle do fluxo de fluido, e conjunto da válvula
BR112015006938A2 (pt) detecção a montante para orifício de equilíbrio
BR112018015456A2 (pt) ?conjunto de controle de fluxo, sistema de poço, e, método de controle de fluxo?
BR112017015483A2 (pt) conjunto, coluna de ferramenta e método
BR112016001860A2 (pt) melhorias em servoválvulas hidráulicas
BR112014002831A2 (pt) válvulas de fluido tendo múltiplos elementos de controle de fluxo de fluido
MX2016012651A (es) Regulador de puerta corrediza.
BR112018014625A2 (pt) elemento de filtro, especialmente para filtragem de gás
BR112015031276A2 (pt) aparelho e método de dispensação de fluido

Legal Events

Date Code Title Description
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B25D Requested change of name of applicant approved

Owner name: ZOETIS DENMARK APS (DK)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 31/01/2017, OBSERVADAS AS CONDICOES LEGAIS