BR112018008629B1 - aparelho para ensaio de um biofluido, aparelho para contenção e dispensa de amostras de biofluido e sistema para dispensa e ensaio de biofluido - Google Patents

aparelho para ensaio de um biofluido, aparelho para contenção e dispensa de amostras de biofluido e sistema para dispensa e ensaio de biofluido Download PDF

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Publication number
BR112018008629B1
BR112018008629B1 BR112018008629-0A BR112018008629A BR112018008629B1 BR 112018008629 B1 BR112018008629 B1 BR 112018008629B1 BR 112018008629 A BR112018008629 A BR 112018008629A BR 112018008629 B1 BR112018008629 B1 BR 112018008629B1
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BR
Brazil
Prior art keywords
biofluid
sample
cuvettes
receptacle
cuvette
Prior art date
Application number
BR112018008629-0A
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English (en)
Portuguese (pt)
Other versions
BR112018008629A2 (pt
Inventor
Rapeechai Navawongse
Ying Song Wang
Visit Thaveeprungsriporn
Yuen Hsia Cheng
Charm Nyein Lynn
Roland Galang Pulido
Feng Liu
Original Assignee
Nitto Denko Corporation
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Publication date
Application filed by Nitto Denko Corporation filed Critical Nitto Denko Corporation
Publication of BR112018008629A2 publication Critical patent/BR112018008629A2/pt
Publication of BR112018008629B1 publication Critical patent/BR112018008629B1/pt

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/25—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0605—Metering of fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/048—Function or devices integrated in the closure enabling gas exchange, e.g. vents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0457—Moving fluids with specific forces or mechanical means specific forces passive flow or gravitation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00564—Handling or washing solid phase elements, e.g. beads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0429—Sample carriers adapted for special purposes
    • G01N2035/0436—Sample carriers adapted for special purposes with pre-packaged reagents, i.e. test-packs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
BR112018008629-0A 2015-11-04 2016-11-04 aparelho para ensaio de um biofluido, aparelho para contenção e dispensa de amostras de biofluido e sistema para dispensa e ensaio de biofluido BR112018008629B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562250573P 2015-11-04 2015-11-04
US62/250,573 2015-11-04
PCT/SG2016/050547 WO2017078630A1 (en) 2015-11-04 2016-11-04 Apparatus and system for biofluid sample dispensing and/or assay

Publications (2)

Publication Number Publication Date
BR112018008629A2 BR112018008629A2 (pt) 2018-10-30
BR112018008629B1 true BR112018008629B1 (pt) 2020-11-17

Family

ID=58662263

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018008629-0A BR112018008629B1 (pt) 2015-11-04 2016-11-04 aparelho para ensaio de um biofluido, aparelho para contenção e dispensa de amostras de biofluido e sistema para dispensa e ensaio de biofluido

Country Status (11)

Country Link
US (2) US11376594B2 (https=)
EP (1) EP3371607A4 (https=)
JP (1) JP6778271B2 (https=)
KR (1) KR102379308B1 (https=)
CN (2) CN108463732B (https=)
AU (1) AU2016350506B2 (https=)
BR (1) BR112018008629B1 (https=)
MY (1) MY188878A (https=)
PH (1) PH12018500959B1 (https=)
SG (1) SG11201803655SA (https=)
WO (1) WO2017078630A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11768215B2 (en) * 2019-01-04 2023-09-26 Funai Electric Co., Ltd. Digital dispense system cartridge
US11474007B2 (en) 2019-01-04 2022-10-18 Funai Electric Co., Ltd. Digital dispense system
CN109929735A (zh) * 2019-04-25 2019-06-25 湖南工业大学 一种柱塞式核酸检测一体化卡盒及其检测方法
WO2021054899A1 (en) * 2019-09-18 2021-03-25 Nitto Denko Corporation Biofluid dispensing and assay apparatuses
CA3154966A1 (en) * 2019-10-21 2021-04-29 Alex DEHGAN Systems and methods for determining presence and/or characteristics of target analytes in a sample
CN111647498B (zh) * 2020-05-25 2022-03-22 杭州梓晶生物有限公司 一种一体化自助式核酸检测装置及其使用方法
EP4053554A1 (en) * 2021-03-02 2022-09-07 EXIAS Medical GmbH Arrangement for analyzing a liquid sample
CN115356180B (zh) * 2022-10-24 2023-01-03 莱阳市检验检测中心 一种食品安全检测仪
WO2024112577A1 (en) * 2022-11-22 2024-05-30 10X Genomics, Inc. Systems and methods for interfacing with a bottle
USD1069156S1 (en) 2023-04-10 2025-04-01 Becton, Dickinson And Company Dispensing device
WO2025184635A1 (en) * 2024-02-29 2025-09-04 Conservation X Labs, Inc. Systems and methods related to sample transfer devices

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0096360B1 (en) * 1982-06-08 1986-09-17 The State of Queensland Sampling device for use in the sampling of biological fluids
DE4018955A1 (de) * 1990-06-13 1991-12-19 Werner Lautenschlaeger Probenbehaelter zum aufschliessen bzw. analysieren von probenmaterial
US5408326A (en) * 1993-04-28 1995-04-18 Shell Oil Company Dual-wavelength absorption detector adapted for continuous-flow detection
AU5305296A (en) * 1995-03-07 1996-09-23 Biomolecular Assays, Inc. Pressure cycling reactor
US5700429A (en) * 1995-04-19 1997-12-23 Roche Diagnostic Systems, Inc. Vessel holder for automated analyzer
CA2236451A1 (en) 1995-11-03 1997-05-09 Zygmunt M. Andrevski Assay system and method for conducting assays
WO1998053912A1 (en) * 1997-05-27 1998-12-03 Qiagen Gmbh Device for selectively filtering under reduced pressure and for vacuum drying sample liquids or drops of sample liquids as well as use of said device
US6043097A (en) * 1997-12-05 2000-03-28 Bayer Corporation Reagent package
US20030215957A1 (en) 1998-02-20 2003-11-20 Tony Lemmo Multi-channel dispensing system
US6387710B1 (en) * 1998-11-04 2002-05-14 Sarnoff Corporation Automated sample processor
US6361746B1 (en) * 1998-11-16 2002-03-26 Julie Ann Wlodarski Medical specimen tote
WO2000049382A2 (en) * 1999-02-16 2000-08-24 The Perkin-Elmer Corporation Bead dispensing system
US6455005B1 (en) * 2000-02-02 2002-09-24 Soltec, Inc. Flexible septa closure plug mats for well plate mounted arrays of sample vials
US6566144B1 (en) * 2000-03-27 2003-05-20 Atrix Laboratories Cover plate for use in lyophilization
US7354774B2 (en) * 2002-05-13 2008-04-08 Becton, Dickinson And Company Self aliquoting sample storage plate
US7000785B2 (en) * 2003-04-03 2006-02-21 Bio-Rad Laboratories, Inc. Tube rack accommodating a range of tube diameters
WO2005012549A2 (en) * 2003-08-01 2005-02-10 Fqubed, Inc. Apparatus and methods for evaluating the barrier properties of a membrane
US7517498B2 (en) * 2003-08-19 2009-04-14 Agilent Technologies, Inc. Apparatus for substrate handling
US9492820B2 (en) * 2003-09-19 2016-11-15 Applied Biosystems, Llc High density plate filler
US8986614B2 (en) * 2010-02-23 2015-03-24 Rheonix, Inc. Self-contained biological assay apparatus, methods, and applications
US9388374B2 (en) * 2005-07-07 2016-07-12 Emd Millipore Corporation Microfluidic cell culture systems
PL1767272T3 (pl) * 2005-09-21 2011-07-29 F Hoffmann La Roche Ltd Uchwyt na kuwety, układ kuwet i analizator składający się z tych części
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
JP4771225B2 (ja) * 2006-12-14 2011-09-14 セイコーエプソン株式会社 分注装置
EP1970711A1 (en) * 2007-03-16 2008-09-17 Radiometer Medical ApS Reagent cup device
EP2030683B1 (de) * 2007-08-17 2013-10-02 Qiagen GmbH Vorrichtung und Verfahren zur Entnahme von Substanzen aus vorgefüllten Behältnissen
US11235323B2 (en) * 2008-08-27 2022-02-01 Life Technologies Corporation Apparatus for and method of processing biological samples
US9492797B2 (en) * 2008-09-23 2016-11-15 Bio-Rad Laboratories, Inc. System for detection of spaced droplets
US9764322B2 (en) * 2008-09-23 2017-09-19 Bio-Rad Laboratories, Inc. System for generating droplets with pressure monitoring
JP5127646B2 (ja) * 2008-09-24 2013-01-23 株式会社日立ハイテクノロジーズ 検体ラック
WO2010115192A2 (en) 2009-04-03 2010-10-07 Integrated Nano-Technologies, Inc. Multi-chamber rotating valve
GB2473868A (en) * 2009-09-28 2011-03-30 Invitrogen Dynal As Apparatus and method of automated processing of biological samples
CN102472695B (zh) * 2009-07-09 2014-07-16 凸版印刷株式会社 核酸提取用试剂盒、核酸提取方法和核酸提取装置
GB0912509D0 (en) * 2009-07-17 2009-08-26 Norchip As A microfabricated device for metering an analyte
US9700889B2 (en) * 2009-11-23 2017-07-11 Cyvek, Inc. Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results
WO2011106315A1 (en) * 2010-02-23 2011-09-01 Rheonix, Inc. Self-contained biological assay apparatus, methods, and applications
US9102979B2 (en) * 2010-02-23 2015-08-11 Rheonix, Inc. Self-contained biological assay apparatus, methods, and applications
US20130287613A1 (en) * 2010-10-07 2013-10-31 Vanderbilt University Peristaltic micropump and related systems and methods
US20120085415A1 (en) * 2010-10-08 2012-04-12 Geneforge, Inc. Well drain system for use with multi-well synthesizer
CN103429331B (zh) * 2010-11-01 2016-09-28 伯乐生命医学产品有限公司 用于形成乳液的系统
CN103648649A (zh) 2011-05-18 2014-03-19 3M创新有限公司 检测选定体积的材料在样本处理装置中存在的系统和方法
US9352312B2 (en) * 2011-09-23 2016-05-31 Alere Switzerland Gmbh System and apparatus for reactions
JP6232383B2 (ja) * 2011-12-03 2017-11-15 イー・エム・デイー・ミリポア・コーポレイシヨン マイクロ流体の細胞培養のためのマイクロインキュベーションシステムおよび方法
KR102114734B1 (ko) * 2012-03-08 2020-05-25 싸이벡, 아이엔씨 미세유체 분석 장치용 마이크로튜브 입자 및 제조방법
EP2662139A1 (en) 2012-05-08 2013-11-13 Roche Diagniostics GmbH A valve for dispensing a fluid
EP2662137A1 (en) * 2012-05-08 2013-11-13 Roche Diagniostics GmbH Dispensing assembly
ES2666795T3 (es) 2012-05-08 2018-05-07 Roche Diagniostics Gmbh Cartucho para dispensar un fluido
US9081001B2 (en) 2012-05-15 2015-07-14 Wellstat Diagnostics, Llc Diagnostic systems and instruments
US9213043B2 (en) * 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
US8900533B2 (en) * 2012-06-29 2014-12-02 Molecular Bioproducts, Inc. Welded blister pack for tips
EP2869924A1 (en) * 2012-07-03 2015-05-13 Merck Patent GmbH Sample preparation device
WO2014015186A1 (en) * 2012-07-18 2014-01-23 Labminds Ltd. Automated solution dispenser
JP6272895B2 (ja) * 2012-12-03 2018-01-31 ザ セクレタリー オブ ステイト フォー エンバイロンメント，フード アンド ルーラル アフェアーズ デバイスおよび装置
EP2952907B1 (en) * 2013-01-31 2020-03-11 Hitachi High-Technologies Corporation Set of cartridge and cartridge holder for use in biochemistry
WO2014138203A2 (en) * 2013-03-05 2014-09-12 Board Of Regents, The University Of Texas System Microfluidic devices for the rapid and automated processing of sample populations
US9409174B2 (en) * 2013-06-21 2016-08-09 Bio-Rad Laboratories, Inc. Microfluidic system with fluid pickups
US20150029322A1 (en) * 2013-07-23 2015-01-29 Qualcomm Incorporated Method and computations for calculating an optical axis vector of an imaged eye
GB2516672B (en) * 2013-07-29 2015-05-20 Atlas Genetics Ltd A system and method for expelling liquid from a fluidic cartridge
WO2015084458A2 (en) * 2013-09-18 2015-06-11 California Institute Of Technology System and method for movement and timing control
US9358543B2 (en) * 2013-11-08 2016-06-07 Covaris, Inc. Vessel holder and cap assembly
EP3077794A4 (en) 2013-12-06 2017-12-13 Bacterioscan Ltd. Optical measurement cuvette having sample chambers
EP3079822B1 (en) 2013-12-12 2019-05-08 3M Innovative Properties Company Method for preparing a biological sample for analysis
MY198335A (en) 2014-02-28 2023-08-25 Nitto Denko Corp Urinalysis Device and Dry Reagent for Quantitative Urinalysis
WO2015161275A1 (en) * 2014-04-18 2015-10-22 Bio-Rad Laboratories, Inc. Microfluidic devices for automated assays
US9827567B2 (en) * 2014-04-22 2017-11-28 Nanosphere, Inc. Diagnostic cartridges having flexible seals
US9975122B2 (en) * 2014-11-05 2018-05-22 10X Genomics, Inc. Instrument systems for integrated sample processing
US9861982B2 (en) * 2015-03-09 2018-01-09 Emd Millipore Corporation Connectors for pneumatic devices in microfluidic systems
US10449539B2 (en) * 2015-08-27 2019-10-22 Rushabh Instruments, Inc. Immuno histo chemistry tissue processing system and cartridge therefor

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PH12018500959A1 (en) 2018-11-19
KR102379308B1 (ko) 2022-03-28
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US11376594B2 (en) 2022-07-05
CN114878802A (zh) 2022-08-09
KR20180070702A (ko) 2018-06-26
BR112018008629A2 (pt) 2018-10-30
CN108463732B (zh) 2022-07-01
EP3371607A4 (en) 2019-06-12
CN108463732A (zh) 2018-08-28
AU2016350506B2 (en) 2022-05-26
JP2018533023A (ja) 2018-11-08
WO2017078630A1 (en) 2017-05-11
JP6778271B2 (ja) 2020-10-28
US20190224680A1 (en) 2019-07-25
SG11201803655SA (en) 2018-05-30
US20220280944A1 (en) 2022-09-08
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PH12018500959B1 (en) 2022-01-19
EP3371607A1 (en) 2018-09-12

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