BR112017010440A2 - administração sublingual de riluzol - Google Patents
administração sublingual de riluzolInfo
- Publication number
- BR112017010440A2 BR112017010440A2 BR112017010440A BR112017010440A BR112017010440A2 BR 112017010440 A2 BR112017010440 A2 BR 112017010440A2 BR 112017010440 A BR112017010440 A BR 112017010440A BR 112017010440 A BR112017010440 A BR 112017010440A BR 112017010440 A2 BR112017010440 A2 BR 112017010440A2
- Authority
- BR
- Brazil
- Prior art keywords
- riluzole
- sublingual administration
- sublingual
- sublingual formulation
- administration
- Prior art date
Links
- FTALBRSUTCGOEG-UHFFFAOYSA-N Riluzole Chemical compound C1=C(OC(F)(F)F)C=C2SC(N)=NC2=C1 FTALBRSUTCGOEG-UHFFFAOYSA-N 0.000 title abstract 4
- 229960004181 riluzole Drugs 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 206010031009 Oral pain Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462083068P | 2014-11-21 | 2014-11-21 | |
| PCT/US2015/061106 WO2016081466A1 (en) | 2014-11-21 | 2015-11-17 | Sublingual administration of riluzole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112017010440A2 true BR112017010440A2 (pt) | 2017-12-26 |
Family
ID=55077617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112017010440A BR112017010440A2 (pt) | 2014-11-21 | 2015-11-17 | administração sublingual de riluzol |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20180153862A1 (enExample) |
| EP (1) | EP3220890A1 (enExample) |
| JP (1) | JP2017535612A (enExample) |
| KR (1) | KR20170137030A (enExample) |
| CN (1) | CN107735077A (enExample) |
| AU (1) | AU2015350142A1 (enExample) |
| BR (1) | BR112017010440A2 (enExample) |
| CA (1) | CA2967659A1 (enExample) |
| EA (1) | EA201791110A1 (enExample) |
| IL (1) | IL252283A0 (enExample) |
| MX (1) | MX2017006454A (enExample) |
| PH (1) | PH12017500933A1 (enExample) |
| SG (1) | SG11201703897SA (enExample) |
| WO (1) | WO2016081466A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| EP3060205A4 (en) | 2013-10-22 | 2017-06-28 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| ES2751300T3 (es) | 2014-11-21 | 2020-03-31 | Biohaven Therapeutics Ltd | Formulación sublingual de riluzol |
| US9899038B2 (en) | 2016-06-30 | 2018-02-20 | Karen Elaine Khaleghi | Electronic notebook system |
| WO2018045217A1 (en) | 2016-08-31 | 2018-03-08 | The General Hospital Corporation | Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases |
| US11331303B2 (en) * | 2016-09-15 | 2022-05-17 | Skintech Life Science Limited | Sublingual or buccal administration of dim for treatment of skin diseases |
| EP3755332A1 (en) | 2018-02-21 | 2020-12-30 | AI Therapeutics, Inc. | Combination therapy with apilimod and glutamatergic agents |
| US10235998B1 (en) * | 2018-02-28 | 2019-03-19 | Karen Elaine Khaleghi | Health monitoring system and appliance |
| AU2019251191A1 (en) * | 2018-04-09 | 2020-10-29 | The General Hospital Corporation | Combination therapies for the treatment of amyotropic lateral sclerosis and related disorders |
| JP2021525714A (ja) * | 2018-05-27 | 2021-09-27 | バイオヘイブン・ファーマシューティカル・ホールディング・カンパニー・リミテッドBiohaven Pharmaceutical Holding Company Ltd. | 疾患の処置のためのリルゾール口腔内崩壊錠の使用 |
| JP2021534160A (ja) * | 2018-08-16 | 2021-12-09 | バイオヘイブン・セラピューティクス・リミテッドBiohaven Therapeutics Ltd. | 疾患処置のためのリルゾール口腔内崩壊錠の使用 |
| MX2021006869A (es) | 2018-12-10 | 2021-07-02 | Massachusetts Gen Hospital | Esteres de cromolin y usos de los mismos. |
| US10559307B1 (en) | 2019-02-13 | 2020-02-11 | Karen Elaine Khaleghi | Impaired operator detection and interlock apparatus |
| WO2021207060A1 (en) | 2020-04-06 | 2021-10-14 | The General Hospital Corporation | Methods of treatment of coronavirus-induced inflammation conditions |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2492258A1 (fr) * | 1980-10-17 | 1982-04-23 | Pharmindustrie | Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole |
| US5837287A (en) * | 1994-10-28 | 1998-11-17 | R P Scherer Corporation | Process for preparing solid pharmaceutical dosage forms |
| FR2787028B1 (fr) * | 1998-12-15 | 2002-10-18 | Aventis Pharma Sa | Utilisation du riluzole dans le traitement des traumatismes acoustiques |
| WO2000074676A1 (en) * | 1999-06-04 | 2000-12-14 | Vereniging Voor Christelijk Wetenschappelikjk Onderwijs | Use of riluzole for the treatment of multiple sclerosis |
| US20040077591A1 (en) * | 2002-03-28 | 2004-04-22 | The Brigham And Women's Hospital, Inc. | Histone deacetylase inhibitors for the treatment of multiple sclerosis, amyotrophic lateral sclerosis and Alzheimer's Disease |
| GB0304636D0 (en) * | 2003-02-28 | 2003-04-02 | Britannia Pharmaceuticals Ltd | Pharmaceutical composition for nasal delivery |
| EP2228054A1 (en) * | 2009-03-13 | 2010-09-15 | ITALFARMACO S.p.A. | Riluzole aqueous suspensions |
| JP2011093849A (ja) * | 2009-10-30 | 2011-05-12 | Kissei Pharmaceutical Co Ltd | トラニラストの易溶性粉末吸入製剤 |
| US9241933B2 (en) * | 2011-03-01 | 2016-01-26 | Pharnext | Compositions for treating amyotrophic lateral sclerosis |
| WO2013010015A2 (en) * | 2011-07-13 | 2013-01-17 | Cytokinetics, Inc. | Combination als therapy |
| CA2864008C (en) * | 2012-03-01 | 2020-04-21 | Pharnext | New compositions for treating amyotrophic lateral sclerosis |
-
2015
- 2015-11-17 EA EA201791110A patent/EA201791110A1/ru unknown
- 2015-11-17 BR BR112017010440A patent/BR112017010440A2/pt not_active Application Discontinuation
- 2015-11-17 CA CA2967659A patent/CA2967659A1/en not_active Abandoned
- 2015-11-17 SG SG11201703897SA patent/SG11201703897SA/en unknown
- 2015-11-17 US US15/100,162 patent/US20180153862A1/en not_active Abandoned
- 2015-11-17 AU AU2015350142A patent/AU2015350142A1/en not_active Abandoned
- 2015-11-17 EP EP15821185.4A patent/EP3220890A1/en not_active Withdrawn
- 2015-11-17 CN CN201580073646.5A patent/CN107735077A/zh active Pending
- 2015-11-17 MX MX2017006454A patent/MX2017006454A/es unknown
- 2015-11-17 KR KR1020177016605A patent/KR20170137030A/ko not_active Withdrawn
- 2015-11-17 JP JP2017545857A patent/JP2017535612A/ja active Pending
- 2015-11-17 WO PCT/US2015/061106 patent/WO2016081466A1/en not_active Ceased
-
2017
- 2017-05-15 IL IL252283A patent/IL252283A0/en unknown
- 2017-05-19 PH PH12017500933A patent/PH12017500933A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2017535612A (ja) | 2017-11-30 |
| MX2017006454A (es) | 2018-03-23 |
| CN107735077A (zh) | 2018-02-23 |
| PH12017500933A1 (en) | 2017-11-20 |
| IL252283A0 (en) | 2017-07-31 |
| AU2015350142A1 (en) | 2017-06-15 |
| EA201791110A1 (ru) | 2017-11-30 |
| WO2016081466A1 (en) | 2016-05-26 |
| EP3220890A1 (en) | 2017-09-27 |
| SG11201703897SA (en) | 2017-06-29 |
| KR20170137030A (ko) | 2017-12-12 |
| US20180153862A1 (en) | 2018-06-07 |
| CA2967659A1 (en) | 2016-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |