BR112016026667A2 - comprimido oralmente desintegrante para administração de avanafil, métodos associados de fabricação e uso de um inibidor de pde v - Google Patents
comprimido oralmente desintegrante para administração de avanafil, métodos associados de fabricação e uso de um inibidor de pde vInfo
- Publication number
- BR112016026667A2 BR112016026667A2 BR112016026667A BR112016026667A BR112016026667A2 BR 112016026667 A2 BR112016026667 A2 BR 112016026667A2 BR 112016026667 A BR112016026667 A BR 112016026667A BR 112016026667 A BR112016026667 A BR 112016026667A BR 112016026667 A2 BR112016026667 A2 BR 112016026667A2
- Authority
- BR
- Brazil
- Prior art keywords
- avanafil
- administration
- manufacturing
- associated methods
- orally disintegrating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461994349P | 2014-05-16 | 2014-05-16 | |
PCT/US2015/031198 WO2015176008A1 (en) | 2014-05-16 | 2015-05-15 | Orally disintegrating dosage form for administration of avanafil, and associated methods of manufacture and use |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112016026667A2 true BR112016026667A2 (pt) | 2017-08-15 |
BR112016026667A8 BR112016026667A8 (pt) | 2021-07-06 |
Family
ID=53284563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016026667A BR112016026667A8 (pt) | 2014-05-16 | 2015-05-15 | comprimido oralmente desintegrante para administração de avanafil, métodos associados de fabricação e uso de um inibidor de pde v |
Country Status (8)
Country | Link |
---|---|
US (4) | US10028916B2 (pt) |
EP (1) | EP3142640A1 (pt) |
AU (1) | AU2015258836B2 (pt) |
BR (1) | BR112016026667A8 (pt) |
CA (1) | CA2949094A1 (pt) |
MX (1) | MX2016014771A (pt) |
RU (1) | RU2740903C2 (pt) |
WO (1) | WO2015176008A1 (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105663066A (zh) * | 2016-04-07 | 2016-06-15 | 山东省药学科学院 | 一种阿伐那非片剂及其制备方法 |
HUE064823T2 (hu) * | 2016-10-24 | 2024-04-28 | Janssen Sciences Ireland Unlimited Co | Diszpergálható készítmények |
WO2018191793A1 (en) * | 2017-04-20 | 2018-10-25 | Zeenar Enterprises Pty Ltd | Fast disintegrating tablet |
EP3612166A4 (en) | 2017-04-20 | 2020-11-04 | Zeenar Enterprises Pty Ltd | LIQUID CRYSTAL GALENIC FORM FOR THE ADMINISTRATION OF STATIN |
US20210145730A1 (en) * | 2017-04-20 | 2021-05-20 | Zeenar Enterprises Pty Ltd | Process for preparing an oral disintegrating dosage form |
BR112021004461A2 (pt) | 2018-09-14 | 2021-05-25 | Cara Therapeutics, Inc. | formulações orais de agonistas do receptor opioide kappa |
CN109696502A (zh) * | 2019-02-22 | 2019-04-30 | 重庆安格龙翔医药科技有限公司 | 气相色谱检测阿伐那非中苯及异亚丙基丙酮残留的方法 |
BR112022018654A2 (pt) | 2020-03-18 | 2023-01-17 | Cara Therapeutics Inc | Formulações de oligossacarídeo de agonistas do receptor opioide kappa |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6743443B1 (en) | 1998-10-05 | 2004-06-01 | Eisai Co., Ltd. | Tablets immediately disintegrating in the oral cavity |
GB0204771D0 (en) | 2002-02-28 | 2002-04-17 | Phoqus Ltd | Fast disintegrating tablets |
US7390503B1 (en) * | 2003-08-22 | 2008-06-24 | Barr Laboratories, Inc. | Ondansetron orally disintegrating tablets |
DE102005009241A1 (de) | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit kontrollierter Bioverfügbarkeit |
US20110182946A1 (en) * | 2008-03-17 | 2011-07-28 | Board Of Regents, The University Of Texas System | Formation of Nanostructured Particles of Poorly Water Soluble Drugs and Recovery by Mechanical Techniques |
EP2808013A1 (en) * | 2008-11-25 | 2014-12-03 | Mitsubishi Tanabe Pharma Corporation | Orally rapidly disintegrating tablet and process for producing same |
WO2013019056A1 (en) | 2011-08-01 | 2013-02-07 | Sam-A Pharm. Co., Ltd. | Novel granule formulation containing sildenafil or pharmaceutically acceptable salts thereof as an active ingredient |
US20150216798A1 (en) * | 2012-08-17 | 2015-08-06 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Novel orally administered pharmaceutical formulations |
-
2015
- 2015-05-15 AU AU2015258836A patent/AU2015258836B2/en not_active Ceased
- 2015-05-15 WO PCT/US2015/031198 patent/WO2015176008A1/en active Application Filing
- 2015-05-15 RU RU2016149464A patent/RU2740903C2/ru active
- 2015-05-15 CA CA2949094A patent/CA2949094A1/en not_active Abandoned
- 2015-05-15 EP EP15727160.2A patent/EP3142640A1/en not_active Withdrawn
- 2015-05-15 BR BR112016026667A patent/BR112016026667A8/pt not_active IP Right Cessation
- 2015-05-15 US US14/714,028 patent/US10028916B2/en active Active
- 2015-05-15 MX MX2016014771A patent/MX2016014771A/es unknown
-
2018
- 2018-06-21 US US16/014,093 patent/US20190133955A1/en not_active Abandoned
-
2019
- 2019-10-02 US US16/590,703 patent/US20200030239A1/en not_active Abandoned
-
2021
- 2021-08-19 US US17/406,165 patent/US20210378964A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20210378964A1 (en) | 2021-12-09 |
US10028916B2 (en) | 2018-07-24 |
RU2016149464A3 (pt) | 2018-08-22 |
MX2016014771A (es) | 2017-02-28 |
RU2740903C2 (ru) | 2021-01-21 |
CA2949094A1 (en) | 2015-11-19 |
US20200030239A1 (en) | 2020-01-30 |
AU2015258836A1 (en) | 2016-12-01 |
AU2015258836B2 (en) | 2020-07-16 |
US20160331687A1 (en) | 2016-11-17 |
RU2016149464A (ru) | 2018-06-19 |
EP3142640A1 (en) | 2017-03-22 |
WO2015176008A1 (en) | 2015-11-19 |
BR112016026667A8 (pt) | 2021-07-06 |
US20190133955A1 (en) | 2019-05-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2670 DE 08-03-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |