BR112016019286A2 - anticorpos do componente c5 do complemento - Google Patents
anticorpos do componente c5 do complementoInfo
- Publication number
- BR112016019286A2 BR112016019286A2 BR112016019286A BR112016019286A BR112016019286A2 BR 112016019286 A2 BR112016019286 A2 BR 112016019286A2 BR 112016019286 A BR112016019286 A BR 112016019286A BR 112016019286 A BR112016019286 A BR 112016019286A BR 112016019286 A2 BR112016019286 A2 BR 112016019286A2
- Authority
- BR
- Brazil
- Prior art keywords
- antibodies
- complement component
- disclosure relates
- complement
- diagnosing
- Prior art date
Links
- 230000000295 complement effect Effects 0.000 title abstract 2
- 230000024203 complement activation Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
a presente divulgação refere-se a anticorpos e polinucleotídeos que codificam os mesmos, que podem ser usados para prevenir, controlar, ou reduzir a atividade da via do complemento. além disso, a divulgação é direcionada a composições e métodos para diagnosticar e tratar doenças mediadas ou que envolvam o c5 do complemento. especificamente, a divulgação refere-se a anticorpos de c5.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461944943P | 2014-02-26 | 2014-02-26 | |
US61/944,943 | 2014-02-26 | ||
PCT/US2015/016699 WO2015127134A2 (en) | 2014-02-20 | 2015-02-19 | Complement component c5 antibodies |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112016019286A2 true BR112016019286A2 (pt) | 2017-10-10 |
BR112016019286B1 BR112016019286B1 (pt) | 2024-02-20 |
Family
ID=62620470
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016019286-9A BR112016019286B1 (pt) | 2014-02-26 | 2015-02-19 | Anticorpo anti-c5 |
Country Status (7)
Country | Link |
---|---|
KR (2) | KR20220164083A (pt) |
CN (2) | CN114716544A (pt) |
BR (1) | BR112016019286B1 (pt) |
DK (1) | DK3107935T3 (pt) |
ES (1) | ES2824262T3 (pt) |
HU (1) | HUE050921T2 (pt) |
IL (1) | IL304203A (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111171149B (zh) * | 2020-02-23 | 2021-09-07 | 北京康普美特创新医药科技有限责任公司 | 一种抗补体c5分子的人源化单链抗体及其应用 |
CN111234016B (zh) * | 2020-02-23 | 2021-09-07 | 北京康普美特创新医药科技有限责任公司 | 一种抗补体c5分子的全人源单克隆抗体及应用 |
CN113754763B (zh) * | 2020-06-05 | 2024-03-08 | 天辰生物医药(苏州)有限公司 | 分离的抗原结合蛋白及其用途 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6074642A (en) * | 1994-05-02 | 2000-06-13 | Alexion Pharmaceuticals, Inc. | Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis |
JP2008520242A (ja) * | 2004-11-18 | 2008-06-19 | イェール ユニバーシティ | 視覚障害を処置するための方法および組成物 |
ZA200707420B (en) * | 2005-02-14 | 2009-04-29 | Univ Iowa Res Found | Methods and reagents for treatment and diagnosis of age-related macular degeneration |
CN101443050A (zh) * | 2006-03-08 | 2009-05-27 | 阿切埃米克斯有限公司 | 治疗视觉失调中使用的补体结合适体和抗-c5药物 |
KR20150029002A (ko) * | 2007-06-07 | 2015-03-17 | 제넨테크, 인크. | 보체-관련 장애의 예방 및 치료를 위한 C3b 항체 및 방법 |
JP5815403B2 (ja) * | 2008-08-05 | 2015-11-17 | ノバルティス アーゲー | 補体タンパク質c5を標的とする抗体に関する組成物および方法 |
BRPI0921237A2 (pt) * | 2008-11-10 | 2015-09-22 | Alexion Pharma Inc | métodos e composições para o tratamento de distúrbios associados ao complemento |
TW201241008A (en) * | 2010-10-01 | 2012-10-16 | Alexion Pharma Inc | Polypeptides that bind to human complement component C5 |
-
2015
- 2015-02-19 BR BR112016019286-9A patent/BR112016019286B1/pt active IP Right Grant
- 2015-02-19 HU HUE15708398A patent/HUE050921T2/hu unknown
- 2015-02-19 KR KR1020227041557A patent/KR20220164083A/ko active Application Filing
- 2015-02-19 CN CN202111467199.5A patent/CN114716544A/zh active Pending
- 2015-02-19 KR KR1020237035361A patent/KR20230149865A/ko active Application Filing
- 2015-02-19 CN CN201580020565.9A patent/CN107207585B/zh active Active
- 2015-02-19 DK DK15708398.1T patent/DK3107935T3/da active
- 2015-02-19 ES ES15708398T patent/ES2824262T3/es active Active
-
2023
- 2023-07-03 IL IL304203A patent/IL304203A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN107207585A (zh) | 2017-09-26 |
HUE050921T2 (hu) | 2021-01-28 |
CN107207585B (zh) | 2021-12-21 |
DK3107935T3 (da) | 2020-09-21 |
KR20230149865A (ko) | 2023-10-27 |
ES2824262T3 (es) | 2021-05-11 |
CN114716544A (zh) | 2022-07-08 |
BR112016019286B1 (pt) | 2024-02-20 |
IL304203A (en) | 2023-09-01 |
KR20220164083A (ko) | 2022-12-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/02/2015, OBSERVADAS AS CONDICOES LEGAIS |