BR112015031772B1 - Uso de células da bainha dérmica não bulbar (nbds) isoladas para a fabricação de uma composição para tratar ou prevenir o envelhecimento da pele ou lesão da pele - Google Patents

Uso de células da bainha dérmica não bulbar (nbds) isoladas para a fabricação de uma composição para tratar ou prevenir o envelhecimento da pele ou lesão da pele Download PDF

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Publication number
BR112015031772B1
BR112015031772B1 BR112015031772-3A BR112015031772A BR112015031772B1 BR 112015031772 B1 BR112015031772 B1 BR 112015031772B1 BR 112015031772 A BR112015031772 A BR 112015031772A BR 112015031772 B1 BR112015031772 B1 BR 112015031772B1
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Brazil
Prior art keywords
cells
nbds
skin
dermal sheath
fact
Prior art date
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BR112015031772-3A
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English (en)
Portuguese (pt)
Other versions
BR112015031772A2 (pt
Inventor
Rolf Hoffmann
Kevin John Mcelwee
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Replicel Life Sciences Inc.
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Publication date
Application filed by Replicel Life Sciences Inc. filed Critical Replicel Life Sciences Inc.
Publication of BR112015031772A2 publication Critical patent/BR112015031772A2/pt
Publication of BR112015031772B1 publication Critical patent/BR112015031772B1/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0627—Hair cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/56—Fibrin; Thrombin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/80—Hyaluronan

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
BR112015031772-3A 2013-06-18 2014-06-18 Uso de células da bainha dérmica não bulbar (nbds) isoladas para a fabricação de uma composição para tratar ou prevenir o envelhecimento da pele ou lesão da pele BR112015031772B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361836634P 2013-06-18 2013-06-18
US61/836,634 2013-06-18
PCT/US2014/043048 WO2014205142A1 (en) 2013-06-18 2014-06-18 Compositions and methods for treating skin

Publications (2)

Publication Number Publication Date
BR112015031772A2 BR112015031772A2 (pt) 2017-07-25
BR112015031772B1 true BR112015031772B1 (pt) 2021-09-08

Family

ID=51162967

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015031772-3A BR112015031772B1 (pt) 2013-06-18 2014-06-18 Uso de células da bainha dérmica não bulbar (nbds) isoladas para a fabricação de uma composição para tratar ou prevenir o envelhecimento da pele ou lesão da pele

Country Status (12)

Country Link
US (2) US20160136206A1 (https=)
EP (1) EP3010515A1 (https=)
JP (4) JP6594301B2 (https=)
KR (2) KR20210114545A (https=)
CN (2) CN116716242A (https=)
AU (1) AU2014281515B2 (https=)
BR (1) BR112015031772B1 (https=)
CA (1) CA2919091A1 (https=)
MX (2) MX385999B (https=)
NZ (1) NZ715905A (https=)
SG (2) SG10201710538XA (https=)
WO (1) WO2014205142A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201506312TA (en) 2013-02-12 2015-09-29 Replicel Life Sciences Inc Compositions and methods for treating and repairing tendons
WO2015123477A1 (en) 2014-02-12 2015-08-20 Replicel Life Sciences Inc. Compositions and methods for treating bone, joints and cartilage
DE102015119880B4 (de) * 2015-11-17 2018-05-24 Technische Universität Berlin Verfahren zur Herstellung von Haarfollikeln und de novo Papillen sowie deren Verwendung für in vitro Tests und in vivo Implantate
WO2017118979A1 (en) * 2016-01-07 2017-07-13 B. G. Negev Technologies And Applications Ltd., At Ben-Gurion University Compositions and methods for generating immunotolerant responses
CN108865975B (zh) * 2018-07-16 2021-11-23 浙江普罗亭健康科技有限公司 斑块组织消化试剂盒及其应用
CN111647550A (zh) * 2020-05-08 2020-09-11 嘉禾弘生(深圳)健康产业集团有限公司 一种组织块酶联合法培养人皮肤成纤维细胞的方法
WO2022071459A1 (ja) * 2020-09-30 2022-04-07 テルモ株式会社 老化細胞判定システム
CN119331808A (zh) * 2024-12-19 2025-01-21 包头市中心医院 一种将小鼠皮肤组织快速消化为单细胞的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556783A (en) * 1991-03-27 1996-09-17 Trustees Of Univ. Of Penna Methods of culturing and modulating the growth of hair follicular stem cells
GB9708692D0 (en) * 1997-04-30 1997-06-18 Jahoda Colin A B Dermal sheath tissue and/or cells derived therefrom in wound healing
US7419661B2 (en) * 1997-04-30 2008-09-02 The Centre Of Excellence For Life Sciences Limited Dermal sheath tissue in wound healing
GB9925964D0 (en) * 1999-11-03 1999-12-29 Jahoda Colin A B Hair transplantation
KR100616752B1 (ko) * 2004-11-29 2006-08-31 박정극 모낭 유도 능력이 있는 모유두 조직의 제조방법
US8206980B2 (en) * 2005-09-30 2012-06-26 Phoenixbio Co., Ltd. Method for cultivation of hair follicular dermal sheath cells
CN101410508B (zh) * 2006-01-27 2013-07-03 加利福尼亚大学董事会 仿生支架
BRPI1011999A2 (pt) * 2009-06-05 2017-06-27 Skinrephair Ltd "uso de células-tronco de bainhas radiculares do cabelo e células precursoras de queratinócitos para a regeneração de pele envelhecida"
KR102025636B1 (ko) * 2011-10-27 2019-11-04 우니베르지태트 라이치히 모낭 외모낭초로부터 멜라닌세포를 유도하기 위한 방법 및 이식을 위한 제조
SG11201506312TA (en) * 2013-02-12 2015-09-29 Replicel Life Sciences Inc Compositions and methods for treating and repairing tendons

Also Published As

Publication number Publication date
CN116716242A (zh) 2023-09-08
SG11201510300RA (en) 2016-01-28
JP2020075907A (ja) 2020-05-21
JP2022008966A (ja) 2022-01-14
US20210106628A1 (en) 2021-04-15
MX2021010546A (es) 2021-10-01
CA2919091A1 (en) 2014-12-24
MX385999B (es) 2025-03-18
MX2015017095A (es) 2016-04-06
KR20210114545A (ko) 2021-09-23
SG10201710538XA (en) 2018-01-30
AU2014281515A1 (en) 2016-02-04
BR112015031772A2 (pt) 2017-07-25
US20160136206A1 (en) 2016-05-19
JP2023174721A (ja) 2023-12-08
NZ715905A (en) 2021-12-24
AU2014281515B2 (en) 2019-11-07
CN105611937A (zh) 2016-05-25
KR20160048056A (ko) 2016-05-03
JP6594301B2 (ja) 2019-10-23
JP2016523254A (ja) 2016-08-08
EP3010515A1 (en) 2016-04-27
WO2014205142A1 (en) 2014-12-24

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
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Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/06/2014, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

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