BR112014020109B1 - Dispositivo para a avaliação de um parâmetro de caracterização de umidade indicativo de olho seco - Google Patents
Dispositivo para a avaliação de um parâmetro de caracterização de umidade indicativo de olho seco Download PDFInfo
- Publication number
- BR112014020109B1 BR112014020109B1 BR112014020109-9A BR112014020109A BR112014020109B1 BR 112014020109 B1 BR112014020109 B1 BR 112014020109B1 BR 112014020109 A BR112014020109 A BR 112014020109A BR 112014020109 B1 BR112014020109 B1 BR 112014020109B1
- Authority
- BR
- Brazil
- Prior art keywords
- electrode
- electrical
- processor
- electrodes
- alternating current
- Prior art date
Links
- 206010013774 Dry eye Diseases 0.000 title claims description 24
- 208000003556 Dry Eye Syndromes Diseases 0.000 title claims description 20
- 238000012512 characterization method Methods 0.000 title claims description 4
- 238000011156 evaluation Methods 0.000 title 1
- 210000004872 soft tissue Anatomy 0.000 claims abstract description 40
- 238000001727 in vivo Methods 0.000 claims abstract description 39
- 210000000744 eyelid Anatomy 0.000 claims abstract description 28
- 238000000338 in vitro Methods 0.000 claims description 18
- 230000002596 correlated effect Effects 0.000 claims description 14
- 239000000758 substrate Substances 0.000 claims description 12
- 238000012360 testing method Methods 0.000 claims description 12
- 230000007246 mechanism Effects 0.000 claims description 10
- 210000001519 tissue Anatomy 0.000 claims description 9
- 239000003990 capacitor Substances 0.000 claims description 6
- 238000010521 absorption reaction Methods 0.000 claims description 4
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- 238000006243 chemical reaction Methods 0.000 claims description 2
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 15
- 238000005259 measurement Methods 0.000 description 11
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- 239000000523 sample Substances 0.000 description 7
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
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- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 3
- 210000004561 lacrimal apparatus Anatomy 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000004743 Polypropylene Substances 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
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- 230000004048 modification Effects 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
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- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
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- 101000939456 Homo sapiens Ubiquitin carboxyl-terminal hydrolase 29 Proteins 0.000 description 1
- 208000015592 Involuntary movements Diseases 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 102100029818 Ubiquitin carboxyl-terminal hydrolase 29 Human genes 0.000 description 1
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- 229910045601 alloy Inorganic materials 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/101—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the tear film
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Eye Examination Apparatus (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1202387.5 | 2012-02-13 | ||
| GBGB1202387.5A GB201202387D0 (en) | 2012-02-13 | 2012-02-13 | Device for in-vivo determination of eye moisture |
| PCT/IB2013/000173 WO2013121263A1 (en) | 2012-02-13 | 2013-02-12 | Device for in-vivo determination of eye moisture |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR112014020109A2 BR112014020109A2 (enExample) | 2017-06-20 |
| BR112014020109A8 BR112014020109A8 (pt) | 2017-07-11 |
| BR112014020109B1 true BR112014020109B1 (pt) | 2021-12-14 |
Family
ID=45929982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014020109-9A BR112014020109B1 (pt) | 2012-02-13 | 2013-02-12 | Dispositivo para a avaliação de um parâmetro de caracterização de umidade indicativo de olho seco |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US9833138B2 (enExample) |
| EP (1) | EP2814378B1 (enExample) |
| JP (1) | JP6086931B2 (enExample) |
| KR (1) | KR102129145B1 (enExample) |
| CN (1) | CN104244805B (enExample) |
| AU (1) | AU2013220118B2 (enExample) |
| BR (1) | BR112014020109B1 (enExample) |
| CA (1) | CA2864421C (enExample) |
| ES (1) | ES2664330T3 (enExample) |
| GB (1) | GB201202387D0 (enExample) |
| IL (1) | IL234084B (enExample) |
| PL (1) | PL2814378T3 (enExample) |
| WO (1) | WO2013121263A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104757972B (zh) * | 2015-03-16 | 2024-02-06 | 思澜科技（成都）有限公司 | 一种用于生物阻抗测量的活检夹 |
| CA2989814A1 (en) | 2015-06-16 | 2016-12-22 | The Regents Of The University Of Colorado, A Body Corporate | Nasolacrimal implants and related methods for tear stimulation |
| ITUB20154761A1 (it) * | 2015-10-29 | 2017-04-29 | Resono Ophthalmic S R L | Sistema di elettrodo e relativo dispositivo per il trattamento di patologie dell?occhio, in particolare dell?occhio secco |
| US10386655B2 (en) | 2016-07-27 | 2019-08-20 | Verily Life Sciences Llc | Device, system and method for detecting overlap of an ophthalmic device by an eyelid |
| KR102342997B1 (ko) * | 2020-05-15 | 2021-12-23 | 충북대학교 산학협력단 | 오스몰 농도 측정 장치 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4996993A (en) * | 1988-12-07 | 1991-03-05 | York Kenneth K | In vivo osmometer |
| US4951683A (en) * | 1989-01-19 | 1990-08-28 | Davis Jeffrey P | Device for detecting keratoconjunctivitis sicca |
| US5961471A (en) | 1995-02-28 | 1999-10-05 | Nova Technology Corporation | Probe for a biophysical skin measurement device |
| US6245064B1 (en) | 1997-07-08 | 2001-06-12 | Atrionix, Inc. | Circumferential ablation device assembly |
| GB2339912B (en) | 1998-07-20 | 2002-06-05 | Univ Bristol | Apparatus and method for measuring the moisture level within enamel dentine or tooth tissue |
| US6553813B2 (en) * | 2000-02-29 | 2003-04-29 | Rynhart Research Limited | Moisture meter with impedance and relative humidity measurements |
| US7051569B2 (en) | 2002-08-06 | 2006-05-30 | Ocusense, Inc. | Systems and methods for calibrating osmolarity measuring devices |
| US8020433B2 (en) | 2003-03-25 | 2011-09-20 | Tearlab Research, Inc. | Systems and methods for a sample fluid collection device |
| US7111502B2 (en) | 2002-08-06 | 2006-09-26 | Ocusense, Inc. | Systems and methods for reducing the effect of corruptive signals during nanoliter osmometry |
| US7905134B2 (en) | 2002-08-06 | 2011-03-15 | The Regents Of The University Of California | Biomarker normalization |
| CA2494540C (en) * | 2002-08-06 | 2014-06-03 | The Regents Of The University Of California | Tear film osmometry |
| JP5449647B2 (ja) * | 2003-08-20 | 2014-03-19 | フィロメトロン，インコーポレイティド | ハイドレーションモニタリング |
| WO2005067651A2 (en) | 2004-01-08 | 2005-07-28 | Cappo Anthony P | Surface plasmon resonance based nanoliter tear osmometer |
| US7297123B2 (en) | 2004-04-19 | 2007-11-20 | Nova Technology Corporation | Method and apparatus for accessing oral mucositis |
| US7182509B2 (en) | 2005-04-27 | 2007-02-27 | Advanced Instruments, Inc. | Nanoliter osmometer and method of operation |
| US7344679B2 (en) * | 2005-10-14 | 2008-03-18 | International Business Machines Corporation | Method and apparatus for point of care osmolarity testing |
| US7908906B2 (en) | 2006-08-29 | 2011-03-22 | International Business Machines Corporation | Fluidic test apparatus and method |
| JP2008154857A (ja) * | 2006-12-25 | 2008-07-10 | Meiyoo:Kk | 角膜抵抗測定装置及びそれに用いられる角膜抵抗測定用電極装置 |
| US7762718B2 (en) | 2007-09-28 | 2010-07-27 | International Business Machines Corporation | Condensation detector utilizing a wet bulb and dry bulb temperature differential |
| US20100069779A1 (en) * | 2008-09-15 | 2010-03-18 | Zvi Nachum | Soft tissue moisture analyzer |
-
2012
- 2012-02-13 GB GBGB1202387.5A patent/GB201202387D0/en not_active Ceased
-
2013
- 2013-02-12 JP JP2014556148A patent/JP6086931B2/ja active Active
- 2013-02-12 EP EP13715738.4A patent/EP2814378B1/en active Active
- 2013-02-12 AU AU2013220118A patent/AU2013220118B2/en active Active
- 2013-02-12 WO PCT/IB2013/000173 patent/WO2013121263A1/en not_active Ceased
- 2013-02-12 BR BR112014020109-9A patent/BR112014020109B1/pt active IP Right Grant
- 2013-02-12 CA CA2864421A patent/CA2864421C/en active Active
- 2013-02-12 KR KR1020147025617A patent/KR102129145B1/ko active Active
- 2013-02-12 CN CN201380019648.7A patent/CN104244805B/zh active Active
- 2013-02-12 ES ES13715738.4T patent/ES2664330T3/es active Active
- 2013-02-12 PL PL13715738T patent/PL2814378T3/pl unknown
-
2014
- 2014-08-12 IL IL234084A patent/IL234084B/en not_active IP Right Cessation
- 2014-08-13 US US14/458,344 patent/US9833138B2/en active Active
-
2017
- 2017-10-29 US US15/796,806 patent/US10716466B2/en active Active
-
2020
- 2020-02-27 US US16/803,389 patent/US20200260947A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2814378A1 (en) | 2014-12-24 |
| US10716466B2 (en) | 2020-07-21 |
| KR102129145B1 (ko) | 2020-07-02 |
| PL2814378T3 (pl) | 2018-07-31 |
| CN104244805A (zh) | 2014-12-24 |
| CA2864421A1 (en) | 2013-08-22 |
| US20180125353A1 (en) | 2018-05-10 |
| BR112014020109A8 (pt) | 2017-07-11 |
| US20200260947A1 (en) | 2020-08-20 |
| US9833138B2 (en) | 2017-12-05 |
| GB201202387D0 (en) | 2012-03-28 |
| CN104244805B (zh) | 2017-10-31 |
| AU2013220118B2 (en) | 2017-10-12 |
| IL234084A0 (en) | 2014-09-30 |
| EP2814378B1 (en) | 2018-01-03 |
| WO2013121263A1 (en) | 2013-08-22 |
| IL234084B (en) | 2020-05-31 |
| US20170347875A9 (en) | 2017-12-07 |
| JP2015513348A (ja) | 2015-05-11 |
| KR20140130473A (ko) | 2014-11-10 |
| US20140350376A1 (en) | 2014-11-27 |
| BR112014020109A2 (enExample) | 2017-06-20 |
| CA2864421C (en) | 2022-03-01 |
| AU2013220118A1 (en) | 2014-09-25 |
| ES2664330T3 (es) | 2018-04-19 |
| JP6086931B2 (ja) | 2017-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 12/02/2013, OBSERVADAS AS CONDICOES LEGAIS. |