BR112013018918A2 - composições de nanopartículas - Google Patents
composições de nanopartículasInfo
- Publication number
- BR112013018918A2 BR112013018918A2 BR112013018918A BR112013018918A BR112013018918A2 BR 112013018918 A2 BR112013018918 A2 BR 112013018918A2 BR 112013018918 A BR112013018918 A BR 112013018918A BR 112013018918 A BR112013018918 A BR 112013018918A BR 112013018918 A2 BR112013018918 A2 BR 112013018918A2
- Authority
- BR
- Brazil
- Prior art keywords
- nanoparticle compositions
- skin
- methods
- chromhidrosis
- bromhidrosis
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/413—Nanosized, i.e. having sizes below 100 nm
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24069—Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Birds (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Dispersion Chemistry (AREA)
- Genetics & Genomics (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161435780P | 2011-01-24 | 2011-01-24 | |
| PCT/US2012/022276 WO2012103035A1 (en) | 2011-01-24 | 2012-01-23 | Nanoparticle compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013018918A2 true BR112013018918A2 (pt) | 2016-10-04 |
Family
ID=45563579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013018918A BR112013018918A2 (pt) | 2011-01-24 | 2012-01-23 | composições de nanopartículas |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20120328702A1 (https=) |
| EP (2) | EP2667854B1 (https=) |
| JP (2) | JP5938838B2 (https=) |
| KR (1) | KR20140003572A (https=) |
| CN (3) | CN103747782A (https=) |
| AU (2) | AU2012209339B2 (https=) |
| BR (1) | BR112013018918A2 (https=) |
| DK (1) | DK2667854T3 (https=) |
| ES (1) | ES2720648T3 (https=) |
| IL (1) | IL227623B (https=) |
| SG (1) | SG193970A1 (https=) |
| TR (1) | TR201905477T4 (https=) |
| WO (1) | WO2012103035A1 (https=) |
| ZA (1) | ZA201306391B (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9486408B2 (en) | 2005-12-01 | 2016-11-08 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
| WO2008070538A2 (en) | 2006-12-01 | 2008-06-12 | Anterios, Inc. | Micellar nanoparticles comprising botulinum toxin |
| MY151973A (en) | 2007-08-17 | 2014-07-31 | Novartis Ag | Cyclic depsipeptides |
| US8680054B2 (en) | 2011-04-20 | 2014-03-25 | Novartis Ag | Suspension type topical formulations comprising cyclic depsipeptide |
| US8614289B2 (en) | 2011-04-20 | 2013-12-24 | Novartis Ag | Processes for the manufacture of macrocyclic depsipeptides and new intermediates |
| US20140051637A1 (en) * | 2011-04-28 | 2014-02-20 | National University Corporation Nagoya University | Brain-targeting functional nucleic acid and use thereof |
| US8987413B2 (en) | 2012-10-09 | 2015-03-24 | Novartis Ag | Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates |
| US9067978B2 (en) | 2012-10-09 | 2015-06-30 | Novartis Ag | Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates |
| WO2015072970A1 (en) * | 2013-11-12 | 2015-05-21 | Colgate-Palmolive Company | Screening methods for antiperspirants |
| AU2015252947B2 (en) * | 2014-05-01 | 2020-07-09 | Anterios, Inc. | Demonstrable efficacy across or within patient populations |
| US10512658B2 (en) | 2015-09-16 | 2019-12-24 | Clutch, Inc. | Compositions for the treatment of sweating and methods for making same |
| US10149805B2 (en) | 2015-09-16 | 2018-12-11 | Clutch, Inc. | Compositions for the treatment of sweating and methods for making same |
| CN105249559A (zh) * | 2015-10-27 | 2016-01-20 | 浙江华尔纺织科技有限公司 | 一种美肤护跟套 |
| JP6873598B2 (ja) * | 2015-12-22 | 2021-05-19 | ロレアル | 活性成分のための改善された局所送達系 |
| KR101679992B1 (ko) | 2015-12-31 | 2016-11-28 | 주식회사 유유제약 | 프로필렌글리콜 모노라우레이트를 포함하는 두타스테리드의 약학적 조성물 및 이의 제조 방법 |
| US20210301289A1 (en) * | 2016-07-29 | 2021-09-30 | Roger L. Kaspar | Methods of treating osmidrosis |
| AU2017360346B2 (en) * | 2016-11-21 | 2023-11-23 | Eirion Therapeutics, Inc. | Transdermal delivery of large agents |
| FR3061434B1 (fr) * | 2017-01-04 | 2019-07-12 | Pierre Fabre Dermo-Cosmetique | Composition cosmetique comprenant une association d'huile de pongamia et de pentylene glycol 4-t-butylcyclohexanol pour lutter contre la rosacee |
| PL3431072T3 (pl) * | 2017-07-17 | 2020-05-18 | Dr. August Wolff Gmbh & Co. Kg Arzneimittel | Emulsja olej-w-wodzie |
| US12280114B2 (en) * | 2018-03-29 | 2025-04-22 | Institute Of Basic Medical Sciences | Extraction of plant source “medicinal soup” and manual preparation of “herbal medicine” and related products |
| BR112021004542A2 (pt) | 2018-09-13 | 2021-06-08 | Eirion Therapeutics, Inc. | inibidores do inibidor de ativador de plasminogênio 1 (pai-1) e usos para os mesmos |
| CA3112549A1 (en) | 2018-09-13 | 2020-03-19 | Eirion Therapeutics, Inc. | Uses of plasminogen activator inhibitor 1 (pai-1) inhibitors |
| BR112021009554A2 (pt) | 2018-12-03 | 2021-08-17 | Eirion Therapeutics, Inc. | aplicação melhorada de agentes grandes |
| EP3914227A1 (en) * | 2019-01-25 | 2021-12-01 | Nogra Pharma Limited | Compositions for use in preventing acne |
| WO2020185685A1 (en) * | 2019-03-08 | 2020-09-17 | The Regents Of The University Of California | Compositions and methods for treating acne |
| US20220273765A1 (en) * | 2019-04-24 | 2022-09-01 | Follicum Ab | Topical formulation |
| CA3139983A1 (en) | 2019-05-14 | 2020-11-19 | Eirion Therapeutics, Inc. | Delaying peak effect and/or extending duration of response |
| MX2022014459A (es) * | 2020-05-18 | 2023-02-27 | Max Biology Co Ltd | Composiciones de lipidos y polimeros y metodos de uso. |
| CN113081905B (zh) * | 2021-04-28 | 2022-11-18 | 媞颂日化用品(广州)有限公司 | 一种仿生皮脂膜组合物及其制备方法和应用 |
| US12599625B2 (en) | 2021-05-13 | 2026-04-14 | Penland Foundation | Treatment of ARDS and other conditions caused by acutely elevated cytokine levels and post ARDS chronic cytokine production using inhaled anesthetics |
| MX2023013932A (es) | 2021-05-25 | 2023-12-08 | Evonik Operations Gmbh | Capsulas de cascara dura con revestimiento de liberacion modificada. |
| KR20240012432A (ko) | 2021-05-25 | 2024-01-29 | 에보니크 오퍼레이션즈 게엠베하 | 위액의 유입이 방지되는 경질-쉘 캡슐 |
| KR20240035523A (ko) | 2021-07-09 | 2024-03-15 | 에보닉 오퍼레이션스 게엠베하 | 결장 방출이 개선된 경질 쉘 캡슐 |
| WO2023287726A1 (en) | 2021-07-12 | 2023-01-19 | Penland Foundation | Treatment of cancer using botulinum toxin and nitrous oxide |
| JP2025508453A (ja) | 2022-02-22 | 2025-03-26 | エボニック オペレーションズ ゲーエムベーハー | 低酸素透過性の少なくとも1つのコーティング層を備える硬質シェルカプセル |
| EP4493165A1 (en) | 2022-03-15 | 2025-01-22 | Evonik Operations GmbH | Pre-functionalized hard shell capsule with accelerated drug release at ph value 5 to 5.5 |
| ES3064012T3 (en) | 2022-05-06 | 2026-04-22 | Evonik Operations Gmbh | Dosage form with drug release at ph 3 to 6 using double coating system with at least one release acceleration agent |
| CN115382476B (zh) * | 2022-07-26 | 2024-10-22 | 华东师范大学 | 一种超小粒径聚合物纳米颗粒的制备方法 |
| JP2026501730A (ja) * | 2023-01-09 | 2026-01-16 | イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブライ ユニバーシティー オブ エルサレム リミテッド | 脱毛症を治療するための局所用組成物及び方法 |
| AU2024344613A1 (en) | 2023-09-18 | 2026-04-23 | Eirion Therapeutics, Inc. | Topical compositions and uses of pai-1 inhibitors |
| CN121754433A (zh) * | 2023-10-31 | 2026-03-31 | 妍诗美社(海南)医美健康科技有限公司 | 一种大分子透皮微乳系统及其应用 |
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-
2012
- 2012-01-23 EP EP12702700.1A patent/EP2667854B1/en active Active
- 2012-01-23 SG SG2013072517A patent/SG193970A1/en unknown
- 2012-01-23 EP EP19151722.6A patent/EP3572072A1/en active Pending
- 2012-01-23 TR TR2019/05477T patent/TR201905477T4/tr unknown
- 2012-01-23 WO PCT/US2012/022276 patent/WO2012103035A1/en not_active Ceased
- 2012-01-23 BR BR112013018918A patent/BR112013018918A2/pt not_active IP Right Cessation
- 2012-01-23 KR KR1020137022334A patent/KR20140003572A/ko not_active Ceased
- 2012-01-23 DK DK12702700.1T patent/DK2667854T3/en active
- 2012-01-23 ES ES12702700T patent/ES2720648T3/es active Active
- 2012-01-23 CN CN201280014473.6A patent/CN103747782A/zh active Pending
- 2012-01-23 CN CN201811111999.1A patent/CN109464393A/zh active Pending
- 2012-01-23 US US13/356,621 patent/US20120328702A1/en not_active Abandoned
- 2012-01-23 AU AU2012209339A patent/AU2012209339B2/en active Active
- 2012-01-23 JP JP2013551268A patent/JP5938838B2/ja active Active
- 2012-01-23 CN CN201710933664.7A patent/CN107714645A/zh active Pending
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2013
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- 2013-08-23 ZA ZA2013/06391A patent/ZA201306391B/en unknown
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2015
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2016
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Also Published As
| Publication number | Publication date |
|---|---|
| EP3572072A1 (en) | 2019-11-27 |
| ES2720648T3 (es) | 2019-07-23 |
| AU2012209339B2 (en) | 2017-05-11 |
| JP2014528900A (ja) | 2014-10-30 |
| KR20140003572A (ko) | 2014-01-09 |
| US20120328702A1 (en) | 2012-12-27 |
| EP2667854A1 (en) | 2013-12-04 |
| AU2017202420A1 (en) | 2017-04-27 |
| WO2012103035A1 (en) | 2012-08-02 |
| CN109464393A (zh) | 2019-03-15 |
| TR201905477T4 (tr) | 2019-05-21 |
| CN107714645A (zh) | 2018-02-23 |
| US20150196490A1 (en) | 2015-07-16 |
| CN103747782A (zh) | 2014-04-23 |
| IL227623A0 (en) | 2013-09-30 |
| AU2012209339A1 (en) | 2013-09-12 |
| DK2667854T3 (en) | 2019-04-23 |
| JP2016121175A (ja) | 2016-07-07 |
| SG193970A1 (en) | 2013-11-29 |
| ZA201306391B (en) | 2014-04-30 |
| IL227623B (en) | 2018-04-30 |
| EP2667854B1 (en) | 2019-01-16 |
| JP5938838B2 (ja) | 2016-06-22 |
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