BR112013016239A2 - proteínas de hemaglutinina da gripe modificada e seus usos - Google Patents
proteínas de hemaglutinina da gripe modificada e seus usosInfo
- Publication number
- BR112013016239A2 BR112013016239A2 BR112013016239A BR112013016239A BR112013016239A2 BR 112013016239 A2 BR112013016239 A2 BR 112013016239A2 BR 112013016239 A BR112013016239 A BR 112013016239A BR 112013016239 A BR112013016239 A BR 112013016239A BR 112013016239 A2 BR112013016239 A2 BR 112013016239A2
- Authority
- BR
- Brazil
- Prior art keywords
- modified
- flu hemagglutinin
- hemagglutinin proteins
- proteins
- flu
- Prior art date
Links
- 101710154606 Hemagglutinin Proteins 0.000 title 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 title 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 title 1
- 101710176177 Protein A56 Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16123—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061426390P | 2010-12-22 | 2010-12-22 | |
| PCT/US2011/066867 WO2012088428A1 (en) | 2010-12-22 | 2011-12-22 | Modified influenza hemagglutinin proteins and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013016239A2 true BR112013016239A2 (pt) | 2016-11-22 |
Family
ID=46314482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013016239A BR112013016239A2 (pt) | 2010-12-22 | 2011-12-22 | proteínas de hemaglutinina da gripe modificada e seus usos |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP2654787A1 (pt) |
| JP (1) | JP2014505681A (pt) |
| KR (1) | KR20140021530A (pt) |
| CN (1) | CN103384531A (pt) |
| AU (1) | AU2011348160A1 (pt) |
| BR (1) | BR112013016239A2 (pt) |
| CA (1) | CA2822443A1 (pt) |
| MX (1) | MX2013007255A (pt) |
| SG (1) | SG191295A1 (pt) |
| WO (1) | WO2012088428A1 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2708552A1 (en) | 2012-09-12 | 2014-03-19 | Medizinische Universität Wien | Influenza virus |
| CN104195113B (zh) * | 2014-08-07 | 2017-05-03 | 扬州大学 | H5亚型禽流感疫苗候选株rS‑156‑/170+/181‑及其构建方法及应用 |
| US10172931B2 (en) * | 2015-05-15 | 2019-01-08 | Reber Genetics Co., Ltd. | Baculovirus display vectors and uses thereof |
| KR101755114B1 (ko) * | 2015-09-08 | 2017-07-06 | 건국대학교 산학협력단 | 여러 클레이드의 고병원성 조류인플루엔자 h5 바이러스에 대한 넓은 항체 반응을 유도하는 키메릭 바이러스 유사입자 백신 |
| US20200237898A1 (en) * | 2015-09-21 | 2020-07-30 | Oregon Health & Science University | Vaccines intelligently produced by epitope recombination (viper) for influenza |
| WO2017053374A1 (en) * | 2015-09-21 | 2017-03-30 | Oregon Health & Science University | Design and characterization of influenza vaccines |
| US20180128545A1 (en) * | 2016-11-08 | 2018-05-10 | Berry Metal Company | Modular furnace cooling wall |
| KR101921384B1 (ko) * | 2016-11-15 | 2018-11-22 | 고려대학교 세종산학협력단 | 인플루엔자 바이러스 표면 단백질 헤마글루티닌 단량체를 포함하는 오소믹소바이러스에 대한 항원 조성물 |
| CA3079486A1 (en) * | 2017-10-18 | 2019-04-25 | Xiamen University | Mutant of hemagglutinin protein of h3n2 subtype influenza virus and use thereof |
| CN109266623B (zh) * | 2018-10-08 | 2021-01-12 | 扬州大学 | 一株疫苗株rSHA-△200及其构建方法和应用 |
| CN110106193B (zh) * | 2019-05-23 | 2021-11-12 | 广州医科大学 | 一种具有低受体结合活性的高致病性h7n9禽流感病毒抗原及其制备方法 |
| CN110106192B (zh) * | 2019-05-23 | 2021-11-12 | 广州医科大学 | 一种具有低受体结合活性的高致病性h7n9禽流感病毒抗原及其制备方法 |
| KR20230038416A (ko) | 2020-05-08 | 2023-03-20 | 아카데미아 시니카 | 키메릭 인플루엔자 백신 |
| TW202334429A (zh) | 2021-10-01 | 2023-09-01 | 中央研究院 | Sars-cov-2棘蛋白特異性抗體及其用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9045727B2 (en) * | 2002-05-17 | 2015-06-02 | Emory University | Virus-like particles, methods of preparation, and immunogenic compositions |
| US8551756B2 (en) * | 2003-07-11 | 2013-10-08 | Novavax, Inc. | Avian influenza chimeric VLPS |
| US8592197B2 (en) * | 2003-07-11 | 2013-11-26 | Novavax, Inc. | Functional influenza virus-like particles (VLPs) |
| US20080014217A1 (en) * | 2006-07-17 | 2008-01-17 | Emmanuel Jules Hanon | Influenza vaccine |
| DK2318530T3 (en) * | 2008-07-18 | 2016-10-03 | Medicago Inc | Ny epitope to immunization against influenza |
-
2011
- 2011-12-22 CA CA2822443A patent/CA2822443A1/en not_active Abandoned
- 2011-12-22 EP EP11849944.1A patent/EP2654787A1/en not_active Withdrawn
- 2011-12-22 JP JP2013546424A patent/JP2014505681A/ja active Pending
- 2011-12-22 WO PCT/US2011/066867 patent/WO2012088428A1/en active Application Filing
- 2011-12-22 MX MX2013007255A patent/MX2013007255A/es not_active Application Discontinuation
- 2011-12-22 SG SG2013048137A patent/SG191295A1/en unknown
- 2011-12-22 BR BR112013016239A patent/BR112013016239A2/pt not_active Application Discontinuation
- 2011-12-22 CN CN2011800682541A patent/CN103384531A/zh active Pending
- 2011-12-22 AU AU2011348160A patent/AU2011348160A1/en not_active Abandoned
- 2011-12-22 KR KR1020137018879A patent/KR20140021530A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN103384531A (zh) | 2013-11-06 |
| CA2822443A1 (en) | 2012-06-28 |
| AU2011348160A1 (en) | 2013-04-04 |
| JP2014505681A (ja) | 2014-03-06 |
| EP2654787A1 (en) | 2013-10-30 |
| WO2012088428A1 (en) | 2012-06-28 |
| MX2013007255A (es) | 2013-09-26 |
| KR20140021530A (ko) | 2014-02-20 |
| SG191295A1 (en) | 2013-07-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |