BR112013012686A2 - "método para obter um composto radiofluorado, e, cassete." - Google Patents

"método para obter um composto radiofluorado, e, cassete."

Info

Publication number
BR112013012686A2
BR112013012686A2 BR112013012686A BR112013012686A BR112013012686A2 BR 112013012686 A2 BR112013012686 A2 BR 112013012686A2 BR 112013012686 A BR112013012686 A BR 112013012686A BR 112013012686 A BR112013012686 A BR 112013012686A BR 112013012686 A2 BR112013012686 A2 BR 112013012686A2
Authority
BR
Brazil
Prior art keywords
cassette
obtaining
compound
radiofluorinated compound
provides
Prior art date
Application number
BR112013012686A
Other languages
English (en)
Inventor
Dimitrios Mantzilas
Eric Horn
Gry Helene Olaussen
Imtiaz Khan
Torild Wickstrom
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of BR112013012686A2 publication Critical patent/BR112013012686A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/84—Separation, e.g. from tar; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)

Abstract

método para obter um composto radiofluorado, e, cassete. a presente invenção provê um método para preparar um composto indol tricíclico marcado com 18f compreendendo etapa de purificação por extração em fase sólida (spe). este método é particularmente adequado para a realização do método de radiofluoração em um sintetizador automatizado. em adição ao método de radiofluoração, a presente invenção proporciona um cassete projetado para realizar o método em um sintetizador automatizado.
BR112013012686A 2010-12-15 2011-12-14 "método para obter um composto radiofluorado, e, cassete." BR112013012686A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42311410P 2010-12-15 2010-12-15
GBGB1021263.7A GB201021263D0 (en) 2010-12-15 2010-12-15 Solid phase extraction method
PCT/EP2011/072781 WO2012080349A1 (en) 2010-12-15 2011-12-14 Solid phase extraction method

Publications (1)

Publication Number Publication Date
BR112013012686A2 true BR112013012686A2 (pt) 2016-09-06

Family

ID=43567233

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013012686A BR112013012686A2 (pt) 2010-12-15 2011-12-14 "método para obter um composto radiofluorado, e, cassete."

Country Status (15)

Country Link
US (1) US9061996B2 (pt)
EP (1) EP2651857B1 (pt)
JP (1) JP6348282B2 (pt)
KR (1) KR20130125780A (pt)
CN (1) CN103249698B (pt)
AU (1) AU2011343347A1 (pt)
BR (1) BR112013012686A2 (pt)
CA (1) CA2819174A1 (pt)
GB (1) GB201021263D0 (pt)
IL (1) IL226335A0 (pt)
MX (1) MX2013006817A (pt)
NZ (1) NZ611988A (pt)
RU (1) RU2013124955A (pt)
SG (1) SG190911A1 (pt)
WO (1) WO2012080349A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2015DN03978A (pt) * 2012-11-30 2015-10-02 Ge Healthcare Ltd
GB201312768D0 (en) 2013-07-17 2013-08-28 Ge Healthcare Ltd Work-up procedure
KR102234143B1 (ko) * 2013-08-22 2021-03-31 지이 헬쓰케어 리미티드 [18f]-플루오로알킬 토실레이트의 개선된 합성
GB201411571D0 (en) 2014-06-30 2014-08-13 Ge Healthcare Ltd Radiolabelling method
GB2531602A (en) * 2014-10-24 2016-04-27 Ge Oil & Gas Uk Ltd Optical amplifier for subsea control systems
CN106999603B (zh) 2014-12-04 2022-05-27 通用电气健康护理有限公司 从放射性药物中除去乙醛的方法
GB201805253D0 (en) * 2018-03-29 2018-05-16 Ge Healthcare Ltd Ip Solid phase extraction
GB201919016D0 (en) * 2019-12-20 2020-02-05 Ge Healthcare Ltd Apparatus and method for solid phase extraction

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004279192A (ja) * 2003-03-14 2004-10-07 Sumitomo Heavy Ind Ltd 放射能予測装置、放射能予測方法、及び、標識化合物製造装置
EP1670519B1 (en) * 2003-09-11 2016-07-13 Mayo Foundation For Medical Education And Research Radiolabeled thymidine solid-phase extraction purification method
US20070219618A1 (en) 2006-03-17 2007-09-20 Cully Edward H Endoprosthesis having multiple helically wound flexible framework elements
JP2010525931A (ja) * 2007-03-09 2010-07-29 ジーイー・ヘルスケア・リミテッド 分離法
GB0905328D0 (en) 2009-03-27 2009-05-13 Ge Healthcare Ltd Indole derivatives

Also Published As

Publication number Publication date
IL226335A0 (en) 2013-07-31
US9061996B2 (en) 2015-06-23
CA2819174A1 (en) 2012-06-21
JP6348282B2 (ja) 2018-06-27
RU2013124955A (ru) 2015-01-20
US20130261315A1 (en) 2013-10-03
JP2014506874A (ja) 2014-03-20
EP2651857B1 (en) 2017-02-15
CN103249698A (zh) 2013-08-14
KR20130125780A (ko) 2013-11-19
CN103249698B (zh) 2016-08-10
AU2011343347A1 (en) 2013-06-06
MX2013006817A (es) 2013-12-06
SG190911A1 (en) 2013-07-31
GB201021263D0 (en) 2011-01-26
NZ611988A (en) 2015-07-31
EP2651857A1 (en) 2013-10-23
WO2012080349A1 (en) 2012-06-21

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]