BR112013010098A2 - método para melhorar a função de transplante usando um receptor do complemento solúvel tipo i (scr1) - Google Patents

método para melhorar a função de transplante usando um receptor do complemento solúvel tipo i (scr1)

Info

Publication number
BR112013010098A2
BR112013010098A2 BR112013010098A BR112013010098A BR112013010098A2 BR 112013010098 A2 BR112013010098 A2 BR 112013010098A2 BR 112013010098 A BR112013010098 A BR 112013010098A BR 112013010098 A BR112013010098 A BR 112013010098A BR 112013010098 A2 BR112013010098 A2 BR 112013010098A2
Authority
BR
Brazil
Prior art keywords
scr1
type
complement receptor
soluble complement
transplant function
Prior art date
Application number
BR112013010098A
Other languages
English (en)
Inventor
Antonius Seelen Marc
Original Assignee
Celldex Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celldex Therapeutics Inc filed Critical Celldex Therapeutics Inc
Publication of BR112013010098A2 publication Critical patent/BR112013010098A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Physiology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BR112013010098A 2010-10-27 2011-10-27 método para melhorar a função de transplante usando um receptor do complemento solúvel tipo i (scr1) BR112013010098A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40733110P 2010-10-27 2010-10-27
PCT/US2011/058163 WO2012058479A2 (en) 2010-10-27 2011-10-27 Method of improving transplant function using soluble complement receptor type i (scr1)

Publications (1)

Publication Number Publication Date
BR112013010098A2 true BR112013010098A2 (pt) 2017-06-13

Family

ID=45994778

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013010098A BR112013010098A2 (pt) 2010-10-27 2011-10-27 método para melhorar a função de transplante usando um receptor do complemento solúvel tipo i (scr1)

Country Status (6)

Country Link
US (1) US9649356B2 (pt)
EP (1) EP2632476B1 (pt)
AU (1) AU2011319746B2 (pt)
BR (1) BR112013010098A2 (pt)
CA (1) CA2815237C (pt)
WO (1) WO2012058479A2 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019204283A1 (en) * 2018-04-16 2019-10-24 Kantum Diagnostics, Inc. Methods of monitoring, treating, and preventing renal inflammation associated with kidney transplantation
WO2019218009A1 (en) 2018-05-16 2019-11-21 Csl Limited Soluble complement receptor type 1 variants and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981481A (en) 1974-12-06 1999-11-09 The Johns Hopkins University Human C3b/C4b receptor (CR1)
US5212071A (en) 1988-04-01 1993-05-18 The Johns Hopkins University Nucleic acids encoding a human C3b/C4b receptor (CR1)
IL89790A (en) 1988-04-01 2002-05-23 Johns Hopking University Sequences of nucleic acids encoding and cells producing CR1 protein and methods for its production and purification
US6458360B1 (en) 1990-04-25 2002-10-01 The Johns Hopkins University Soluble complement regulatory molecules
US5252216A (en) 1992-03-24 1993-10-12 Smithkline Beecham Corporation Protein purification
US5456909A (en) 1992-08-07 1995-10-10 T Cell Sciences, Inc. Glycoform fractions of recombinant soluble complement receptor 1 (sCR1) having extended half-lives in vivo
AU685433B2 (en) * 1993-02-12 1998-01-22 Regents Of The University Of Minnesota Pulmonary administration of sCR1 and other complement inhibitory proteins
CA2162600C (en) 1993-05-17 2000-07-11 Chrales W. Rittershaus Compositions comprising complement related proteins and carbohydrates, and methods for producing and using said compositions
ATE213639T1 (de) 1993-07-09 2002-03-15 Avant Immunotherapeutics Inc Proteinreinigung
WO1997011601A1 (en) * 1995-09-28 1997-04-03 The Johns Hopkins University School Of Medicine Method for prevention of xenograft rejection by transplant recipients
GB9614871D0 (en) 1996-07-15 1996-09-04 Smithkline Beecham Plc Compounds

Also Published As

Publication number Publication date
WO2012058479A2 (en) 2012-05-03
EP2632476A4 (en) 2015-04-01
WO2012058479A3 (en) 2014-04-10
CA2815237A1 (en) 2012-05-03
US9649356B2 (en) 2017-05-16
AU2011319746A1 (en) 2013-05-02
EP2632476B1 (en) 2017-06-14
US20120232020A1 (en) 2012-09-13
CA2815237C (en) 2018-10-09
AU2011319746B2 (en) 2015-07-30
EP2632476A2 (en) 2013-09-04

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B350 Update of information on the portal [chapter 15.35 patent gazette]