BR112012030944A2 - método para a produção de ligantes para beta amiloide marcados com f-18 - Google Patents
método para a produção de ligantes para beta amiloide marcados com f-18Info
- Publication number
- BR112012030944A2 BR112012030944A2 BR112012030944A BR112012030944A BR112012030944A2 BR 112012030944 A2 BR112012030944 A2 BR 112012030944A2 BR 112012030944 A BR112012030944 A BR 112012030944A BR 112012030944 A BR112012030944 A BR 112012030944A BR 112012030944 A2 BR112012030944 A2 BR 112012030944A2
- Authority
- BR
- Brazil
- Prior art keywords
- producing
- beta amyloid
- labeled beta
- binders
- amyloid binders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/77—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing carboxyl groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10164946 | 2010-06-04 | ||
| PCT/EP2011/058817 WO2011151281A1 (en) | 2010-06-04 | 2011-05-30 | Method for production of f-18 labeled amyloid beta ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112012030944A2 true BR112012030944A2 (pt) | 2016-11-01 |
Family
ID=44627058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012030944A BR112012030944A2 (pt) | 2010-06-04 | 2011-05-30 | método para a produção de ligantes para beta amiloide marcados com f-18 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20140012032A1 (pt) |
| EP (1) | EP2575900A1 (pt) |
| JP (1) | JP2013527211A (pt) |
| KR (1) | KR20130088118A (pt) |
| CN (1) | CN103328012A (pt) |
| AU (1) | AU2011260419A1 (pt) |
| BR (1) | BR112012030944A2 (pt) |
| CA (1) | CA2801525A1 (pt) |
| EA (1) | EA201201647A1 (pt) |
| MX (1) | MX2012014116A (pt) |
| SG (1) | SG185783A1 (pt) |
| TW (1) | TW201204394A (pt) |
| WO (1) | WO2011151281A1 (pt) |
| ZA (1) | ZA201209126B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140243533A1 (en) * | 2011-10-19 | 2014-08-28 | Piramal Imaging Sa | Method for production of f-18 labeled a-beta ligands |
| KR101326000B1 (ko) * | 2012-01-30 | 2013-11-07 | 재단법인 아산사회복지재단 | 수소이온 농도가 조절된 플루오린-18의 용리액 제조 및 이를 이용한 플루오린-18의 표지방법 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100789847B1 (ko) * | 2004-12-15 | 2007-12-28 | (주)퓨쳐켐 | 알코올 용매하에서 유기플루오로 화합물의 제조방법 |
| DK2213652T3 (en) | 2004-12-17 | 2015-01-26 | Univ Pennsylvania | Stilbene AND USE THEREOF FOR BINDING AND IMAGING OF amyloid plaques |
| US7687052B2 (en) * | 2006-03-30 | 2010-03-30 | The Trustees Of The University Of Pennsylvania | Styrylpyridine derivatives and their use for binding and imaging amyloid plaques |
| EP2297070A2 (en) * | 2008-07-03 | 2011-03-23 | Bayer Schering Pharma Aktiengesellschaft | Compounds and processes for production of radiopharmaceuticals |
| US8968701B2 (en) * | 2009-07-10 | 2015-03-03 | Piramal Imaging Sa | Usage of low to medium-pressure liquid chromatography for the purification of radiotracers |
-
2011
- 2011-05-30 EP EP11725374.0A patent/EP2575900A1/en not_active Withdrawn
- 2011-05-30 KR KR1020137000137A patent/KR20130088118A/ko not_active Application Discontinuation
- 2011-05-30 CN CN201180027668XA patent/CN103328012A/zh active Pending
- 2011-05-30 CA CA2801525A patent/CA2801525A1/en not_active Abandoned
- 2011-05-30 BR BR112012030944A patent/BR112012030944A2/pt not_active IP Right Cessation
- 2011-05-30 JP JP2013512856A patent/JP2013527211A/ja active Pending
- 2011-05-30 MX MX2012014116A patent/MX2012014116A/es not_active Application Discontinuation
- 2011-05-30 SG SG2012087375A patent/SG185783A1/en unknown
- 2011-05-30 EA EA201201647A patent/EA201201647A1/ru unknown
- 2011-05-30 US US13/702,002 patent/US20140012032A1/en not_active Abandoned
- 2011-05-30 WO PCT/EP2011/058817 patent/WO2011151281A1/en active Application Filing
- 2011-05-30 AU AU2011260419A patent/AU2011260419A1/en not_active Abandoned
- 2011-05-31 TW TW100119100A patent/TW201204394A/zh unknown
-
2012
- 2012-12-03 ZA ZA2012/09126A patent/ZA201209126B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2801525A1 (en) | 2011-12-08 |
| JP2013527211A (ja) | 2013-06-27 |
| CN103328012A (zh) | 2013-09-25 |
| EA201201647A1 (ru) | 2013-05-30 |
| SG185783A1 (en) | 2013-01-30 |
| US20140012032A1 (en) | 2014-01-09 |
| TW201204394A (en) | 2012-02-01 |
| EP2575900A1 (en) | 2013-04-10 |
| ZA201209126B (en) | 2013-08-28 |
| WO2011151281A1 (en) | 2011-12-08 |
| AU2011260419A1 (en) | 2012-12-20 |
| KR20130088118A (ko) | 2013-08-07 |
| MX2012014116A (es) | 2013-08-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |