BR112012030794A2 - novos compostos imunoadjuvantes e usos dos mesmos - Google Patents

novos compostos imunoadjuvantes e usos dos mesmos

Info

Publication number
BR112012030794A2
BR112012030794A2 BR112012030794A BR112012030794A BR112012030794A2 BR 112012030794 A2 BR112012030794 A2 BR 112012030794A2 BR 112012030794 A BR112012030794 A BR 112012030794A BR 112012030794 A BR112012030794 A BR 112012030794A BR 112012030794 A2 BR112012030794 A2 BR 112012030794A2
Authority
BR
Brazil
Prior art keywords
new
compounds
immunoadjuvant
immunoadjuvant compounds
new immunoadjuvant
Prior art date
Application number
BR112012030794A
Other languages
English (en)
Other versions
BR112012030794B1 (pt
Inventor
Martirosyan Anna
Klechevsky Aynav
Banchereau Jacques
Gorvel Jean-Pierre
Oh Sangkon
Original Assignee
Centre Nat Rech Scient
Inserm ( Inst Nat De La Santé Et De La Rech Médicale)
Univ D'aix-Marseille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Inserm ( Inst Nat De La Santé Et De La Rech Médicale), Univ D'aix-Marseille filed Critical Centre Nat Rech Scient
Publication of BR112012030794A2 publication Critical patent/BR112012030794A2/pt
Publication of BR112012030794B1 publication Critical patent/BR112012030794B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

novos compostos imunoadjuvantes e uso dos mesmos. a presente invenção se refere a um composto de beta glucano cíclico para uso como um imunoadjuvante e composição de vacina que compreende o mesmo. estes novos compostos adjuvantes representam, em particular, uma nova classe de moléculas de ativação de células dendríticas.
BR112012030794-0A 2010-06-04 2011-06-06 Novos compostos imunoadjuvantes e usos dos mesmos BR112012030794B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10305596.8 2010-06-04
EP10305596 2010-06-04
PCT/EP2011/059287 WO2011151471A1 (en) 2010-06-04 2011-06-06 Novel immunoadjuvant compounds and uses thereof

Publications (2)

Publication Number Publication Date
BR112012030794A2 true BR112012030794A2 (pt) 2017-05-23
BR112012030794B1 BR112012030794B1 (pt) 2019-11-26

Family

ID=42790846

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012030794-0A BR112012030794B1 (pt) 2010-06-04 2011-06-06 Novos compostos imunoadjuvantes e usos dos mesmos

Country Status (9)

Country Link
US (1) US9061066B2 (pt)
EP (1) EP2575877B1 (pt)
JP (1) JP5860871B2 (pt)
KR (1) KR101736487B1 (pt)
CN (1) CN103096923B (pt)
BR (1) BR112012030794B1 (pt)
CA (1) CA2800424C (pt)
ES (1) ES2607798T3 (pt)
WO (1) WO2011151471A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013040027A1 (en) * 2011-09-12 2013-03-21 Baylor Research Institute Reprogramming immune environment in breast cancer via dendritic cells
CN102600467B (zh) * 2012-03-29 2016-06-01 戚春建 β-葡聚糖在制备人树突状细胞肿瘤疫苗中的应用
CN102600462B (zh) * 2012-03-29 2015-06-17 戚春建 人树突状细胞肿瘤疫苗及其制备方法和应用
JP2021501186A (ja) 2017-10-30 2021-01-14 ユニバーシティ オブ サザン カリフォルニア 感染を防止するための免疫予防へのマルチアジュバントのみアプローチのための組成物および方法
US20210187064A1 (en) * 2018-05-07 2021-06-24 Administrators Of The Tulane Educational Fund Mutated e. coli enterotoxins as anti-inflammatory agents
EP3923981A4 (en) * 2019-02-15 2022-11-30 Cleveland Clinic Foundation VACCINE ADJUVANTS AND FORMULATIONS
WO2023183080A1 (en) 2022-03-21 2023-09-28 University Of Southern California Triple vaccine protects against bacterial and fungal pathogens via trained immunity

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4532009A (en) 1983-04-01 1985-07-30 Albany International Forming board elements
JPS6170994A (ja) 1984-09-14 1986-04-11 Daikin Ind Ltd 環状（１→２）−β−Ｄ−グルカンの製法
US6444210B1 (en) * 1996-07-03 2002-09-03 Her Majesty the Queen in right of Canada, as represented by the Minister of National Defence of Her Majesty′s Canadian Goverment Bacterial and synthetic polysaccharide immunomodulators that enhance general immunity
US6303347B1 (en) * 1997-05-08 2001-10-16 Corixa Corporation Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors
EP1315559B1 (en) 2000-08-18 2006-03-22 Massachusetts Institute Of Technology Apparatus and methods for the automated synthesis of oligosaccharides
WO2004026238A2 (en) 2002-09-20 2004-04-01 Dendreon Corporation Immunotherapeutic compositions and methods for the treatment of moderately to well-differentiated cancers
EP1550458A1 (en) * 2003-12-23 2005-07-06 Vectron Therapeutics AG Synergistic liposomal adjuvants
EP1762575A1 (en) * 2005-09-12 2007-03-14 Ganymed Pharmaceuticals AG Identification of tumor-associated antigens for diagnosis and therapy
EP1787660A1 (en) * 2005-11-22 2007-05-23 GBF Gesellschaft für Biotechnologische Forschung mbH New adjuvants on the basis of bisacyloxypropylcysteine conjugates and their uses in pharmaceutical compositions
HUE045093T2 (hu) * 2008-11-21 2019-12-30 Kobenhavns Univ University Of Copenhagen Immunválasz kiváltása

Also Published As

Publication number Publication date
US20130129756A1 (en) 2013-05-23
BR112012030794B1 (pt) 2019-11-26
CN103096923B (zh) 2017-11-14
CA2800424A1 (en) 2011-12-08
JP5860871B2 (ja) 2016-02-16
JP2013527219A (ja) 2013-06-27
US9061066B2 (en) 2015-06-23
CA2800424C (en) 2018-10-23
ES2607798T3 (es) 2017-04-04
KR101736487B1 (ko) 2017-05-17
EP2575877B1 (en) 2016-10-19
CN103096923A (zh) 2013-05-08
KR20130130674A (ko) 2013-12-02
EP2575877A1 (en) 2013-04-10
WO2011151471A1 (en) 2011-12-08

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: INSERM ( INSTITUT NATIONAL DE LA SANTE ET DE LA RE

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06T Formal requirements before examination [chapter 6.20 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/06/2011, OBSERVADAS AS CONDICOES LEGAIS. (CO) 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/06/2011, OBSERVADAS AS CONDICOES LEGAIS

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 13A ANUIDADE.