BR112012010650B1 - COMPOSITION FOR RELEASE OF BENEFIT AGENT AND CONSUMER PRODUCT - Google Patents

Abstract

release particle. The present application relates to benefit agent release compositions comprising a material selected from the group consisting of agglomerates comprising chelating agent and an encapsulated benefit agent, agglomerates comprising an encapsulated benefit agent having a housing comprising chelator, agglomerates comprising an encapsulated benefit agent having a core comprising chelator and combinations thereof, and processes for producing and using such benefit agent release compositions.

Description

Descriptive Report of the Invention Patent for COMPOSITION FOR RELEASE OF BENEFIT AGENT AND PRODUCT INTENDED FOR THE CONSUMER.

FIELD OF THE INVENTION

The present application relates to agglomerates / particles comprising encapsulated benefit agents, compositions comprising such agglomerates / particles, and processes for the production and use of such agglomerates / particles and compositions comprising such agglomerates / particles.

BACKGROUND OF THE INVENTION

Beneficial agents, such as perfumes, silicones, waxes, flavors, vitamins and fabric softening agents, are expensive and, in general, less effective when used in high amounts in personal care compositions, cleaning compositions and fabric treatment compositions . As a result, there is a desire to maximize the effectiveness of such beneficial agents. One method to achieve this goal is to optimize the release efficiency of such beneficial agents. Unfortunately, it is difficult to improve the efficiency of release of beneficial agents, as these agents may be lost due to their physical and chemical characteristics, or such agents may be incompatible with other compositional components or with the situs being treated.

In an effort to optimize the release efficiencies of benefit agents, the industry, in many cases, provides such benefit agents in an encapsulated form. Unfortunately, in some cases, beneficial agents, for example, raw materials for perfume and flavorings, may degrade over time. This results in reduced effectiveness and / or the need for additional quantities of such materials to compensate for the loss.

Consequently, there is a need for a benefit release process and agent that minimizes or eliminates one or more problems associated with the use of encapsulants.

SUMMARY OF THE INVENTION

This application relates to compositions for the release of

Petition 870190034139, of 10/04/2019, p. 7/13

2/57 benefit agents comprising a material selected from the group consisting of: a particleboard, particulate and / or extruded material comprising chelating agent and an encapsulated benefit agent that has a core and a housing encapsulating said core, a particleboard, particulate and / or extruded which comprises a chelator and an encapsulated benefit agent having a core and a housing encapsulating said core, said encapsulated benefit agent comprising chelating in its housing and / or core, a particleboard, particulate and / or extruded which comprises an encapsulated benefit agent that has a core and a housing encapsulating said core, said encapsulated benefit agent comprising chelating in its housing and / or core and combinations thereof, and processes for the production and use of such compositions for release of benefit agent.

DETAILED DESCRIPTION OF THE INVENTION

Definitions

For use in the present invention, the term consumer products includes, except where otherwise indicated, baby care articles, beauty care, fabric care and home care, family care, female care, skin care. health, snack and / or beverage products, or devices intended to be used or consumed in the form in which they are sold, and which are not intended for subsequent commercial production or modification. These products include, but are not limited to, diapers, bibs, hygienic wipes; products and / or methods related to hair treatment (human, dogs and / or cats), including bleaching, coloring, dyeing, conditioning, shampoo, hairstyles; deodorants and antiperspirants; personal hygiene; cosmetics; skin treatment including the application of creams, lotions and other products for topical application for consumer use, and products for shaving or hair removal, products and / or methods related to the treatment of fabrics, hard surfaces and any other surfaces in the care area home care, including: air care, car care, dish washing, fabric conditioning (including

3/57 softener), detergent for washing clothes, additive for washing and rinsing and / or care, cleaning and / or treatment of hard surfaces and other cleaning products for consumer use or institutional use; products and / or methods related to toilet paper, facial tissues, tissues and / or paper towels; tampons, sanitary pads, products and / or methods related to oral treatment including toothpastes, dental gels, mouthwashes, denture adhesives, tooth whiteners, over-the-counter health care products including cough and cold remedies, pain relievers, drugs sold under prescription, pet health and nutrition and water purification; processed food products intended primarily for consumption between routine meals or to accompany meals (non-limiting examples include potato chips, tortilla chips, popcorn, pretzels, corn chips, cereal bars, vegetable chips or crisps, snack mixes , party mixes, multi-grain chip snacks, snack crackers, cheese snacks, pork pururuca, corn snacks, pellet snacks, extruded snacks and bagel chips), and coffee.

For use in the present invention, the term cleaning composition includes, except where otherwise indicated, washing agents in granulated or powder form, for multiple purposes or for heavy duty, especially cleaning detergents; washing agents for multiple purposes in the form of liquid, gel or paste, especially those of the liquid type for heavy duty; liquid detergents for delicate fabrics; manual dishwashing agents or dishwashing agents for light tasks, especially those of the foamy type; dishwashing agents, including various types of tablets, granular, liquid and rinse aid for domestic and institutional use; liquid cleaning and disinfecting agents, including types of bactericide for hand washing, cleaning bars, mouthwashes, denture cleaners, toothpaste, car or carpet shampoos, bathroom cleaners; shampoos and conditioners with head rinse

4/57

Io; shower gels and bubble baths and metal cleaners; as well as auxiliary cleaning compounds such as bleach additives and stain-removing sticks or types for pretreatment, substrate loaded products such as sheets for addition to machine drying, dry and moistened cleaning cloths and pads, non-woven substrates and sponges ; as well as sprays and nebulizers.

For use in the present invention, the term chelating agent means an agent capable of forming a complex with a metal ion.

For use in the present invention, the term polyidentate of a chelating type means a chelator capable of forming a complex with a metal ion at two or more points.

For use in the present invention, the term fabric treatment composition includes, except where otherwise indicated, fabric softening compositions, fabric optimization compositions, fabric renewing compositions and combinations thereof.

For use in the present invention, the terms encapsulated benefit agent and release particle containing benefit agent are synonymous, and the terms capsule and microcapsule are synonymous.

For use in the present invention, articles including one and one, when used in a claim, are understood to mean one or more of what is claimed or described.

For use in the present invention, the terms include, include and including are intended to be non-limiting.

The test methods presented in the test method section of this application need to be used to determine the respective parameter values of the Applicants' inventions.

Except where otherwise specified, all component or composition levels refer to the active portion of that component or composition and are exclusive of impurities, for example, residual solvents or by-products, which may be present in commercially available sources of such components or compositions.

All percentages and ratios are calculated by weight, except

5/57 to where otherwise indicated. All percentages and ratios are calculated based on the total composition, except where indicated otherwise.

It should be understood that each maximum numerical limit mentioned in this specification includes each of the lower numerical limits, as if such lower numerical limits were expressly registered in this document. Each minimum numerical limit mentioned in this specification includes each of the upper numerical limits, as if such upper numerical limits were expressly registered in this document. Each numerical range mentioned in this specification includes each more restricted number range that is within that broader number range, as if such more restricted number ranges were expressly recorded in this document.

Composition for Releasing Beneficial Agents - Aggregate / Particle / Extruded

The Applicants recognized that specific materials used as beneficial agents — in particular materials that comprise portions of aldehyde, for example, certain perfumes and flavorings — when encapsulated, degrade at unexpectedly higher rates. Without adhering to the theory, Applicants believe that the degradation of such materials may be the result of oxidation by oxygen in the presence of catalytic materials. For example, Claimants believe that degradation of perfume raw materials may be the result of oxidation by oxygen in the presence of metal catalysts such as Fe. Specifically, Claimants believe that Fe ₂ Os — which may be a common impurity in the silica used to prepare encapsulates such as those described here — may result in Fe catalysis of oxidation of aldehyde to carboxylic acid by oxygen, resulting in the degradation of materials containing encapsulated aldehyde. The Applicants recognized that, by adding a chelator, such degradation can be significantly reduced.

In one aspect, a benefit agent release composition is presented that comprises a material selected from the group

6/57 consisting of: an agglomerate, particulate and / or extruded comprising chelator and an encapsulated benefit agent having a core and a housing encapsulating said core; a particulate and / or extruded agglomerate comprising chelator and an encapsulated benefit agent having a core and a housing encapsulating said core, said encapsulated benefit agent comprising chelating in its housing and / or core; a particulate and / or extruded agglomerate comprising an encapsulated benefit agent having a core and a housing encapsulating said core, the encapsulated benefit agent comprising chelating in its housing and / or core and combinations thereof.

In one aspect, a benefit agent release composition that can be an agglomerate, particulate and / or extruded material that can comprise, based on the total weight of the benefit agent:

The. ) from about 2% to about 97%, from about 10% to about 90%, from about 15% to about 85%, from about 20% to about 80%, about 25% to about 75%, or even about 30% to about 70% of an encapsulated benefit agent, said encapsulated benefit agent comprising a core and a housing encapsulating said benefit agent, said Encapsulated benefit comprises a sufficient amount of benefit agent to provide, based on the total weight of the benefit release agent composition, from about 1% to about 85%, from about 8% to about 80%, of about 12% to about 75%, about 15% to about 65%, about 20% to about 60%, or even about 25% to about 55% beneficial agent;

B. ) a chelating agent, said chelating agent being present in said benefit agent release composition, and / or in the housing and / or core of said encapsulated benefit agent;

ç. ) from about 1% to about 50%, from about 2% to about 45%, from about 3% to about 40%, from about 4% to about 37%, about 5% about 35%, or even about 6% to about 30% of

7/57 a plasticizer;

d. ) from about 1% to about 50%, from about 2% to about 45%, from about 3% to about 35%, from about 4% to about 30%, about 5% about 25%, or even about 6% to about 20% of a binder, and

and. ) optionally, from about 1% to about 50%, from about 2% to about 45%, from about 5% to about 40%, from about 7% to about 35%, about 9% to about 30%, or even from about 10% to about 27% of a dusting agent is presented.

And an aspect of the aforementioned benefit agent release composition, said encapsulated benefit agent may comprise a perfume microcapsule, a binder and mixtures thereof. In one aspect, said perfume microcapsule may comprise a carcass, said carcass comprising crosslinked formaldehyde melamine.

In one aspect of the aforementioned benefit agent release composition,

The. ) said encapsulated benefit agent may comprise a perfume microcapsule, said perfume microcapsule comprising a core and a housing encapsulating said core, said housing and / or core comprising crosslinked formaldehyde melamine and a chelating agent;

B. ) said plasticizer may comprise water;

ç. ) said binder can be selected from the group consisting of celluloses, including methyl cellulose, including CMC, and derivatives of these substances; alginate and derivatives of these substances; starches; polyvinyl alcohols; polyethylene oxide; polyvinyl pyrrolidone; polysaccharides including chitosan and / or natural gums including carrageenan; polyacrylates including cross-linked polyacrylates; waxes; polyethylene glycols, for example, polyethylene glycols with a molecular weight (weight average) greater than 4000 Da or even from about 4000 Da to about 15,000 Da; alcohol ethoxylates; surfactants and mixtures thereof, and

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d.) said dust removal agent can be selected from the group consisting of silicas; zeolites; amorphous aluminum silicates; clays; starches; celluloses; water-soluble salts including sodium chloride, sodium sulfate, magnesium sulfate and / or sodium carbonate; polysaccharides including sugars, and mixtures thereof.

In one aspect, any of the benefit agent release compositions presented in this specification can comprise an encapsulated benefit agent that can comprise a benefit agent selected from the group consisting of perfumes; whitening; insect repellents; silicones; waxes; flavoring; vitamins; fabric softening agents; skin care agents including paraffins; enzymes; bactericidal agents; bleaches, and mixtures thereof. In one aspect, the encapsulated beneficial agent is a perfume that comprises an aldehyde.

In one aspect, any of the beneficial agent release compositions disclosed in the present specification may comprise a chelator selected from the group consisting of chelators comprising a polyidentate comprising a soft base; chelators that comprise a polyidentate that does not comprise a soft base, and combinations thereof.

In one aspect, any of the beneficial agent release compositions disclosed in the present specification may comprise a chelator comprising a polyidentate comprising a soft base, as determined by the Lewis definition of atoms with an isolated electron pair in the molecular orbit highest occupied. In that respect, said chelator comprising a polyidentate comprising a soft base may be present in an amount of about 0.0001% to about 10%, or from about 0.01% to about 0.1%, based on the total weight of the cluster. In one aspect, said polyidentate comprising a soft base may comprise a material selected from the group consisting of polyamines (for example, diethylene triamine, triethylene triamine, polyethylene imines); aminoalcohols (for example, triethanol amine, N

9/57 hydroxy ethyl ethylene diamine, amino ethyl ethanolamine (AEEA); amino carboxylic acids, (eg ethylenediamine tetraacetic acid (EDTA), diethylene triamine penta (methylene phosphonic acid) (DTPMP), diethylene triamine pentaacetic acid (DTPA), ethylenediamine, diethylene triamine, ethylenediamine disuccinic acid (EDDS) , N-hydroxy ethyl ethylene diamine triacetic acid (HEDTA), triethylene tetraamine hexaacetic acid (TTHA), N-hydroxy ethyl iminodiacetic acid (HEIDA), ethylglycine dihydroxy (DHEG), ethylenediamine tetra propionic acid (EDTP)) and combinations of themselves. In one aspect, the polyidentate comprising a soft base may comprise disuccinic ethylenediamine acid.

In one aspect, any of the beneficial agent release compositions disclosed in the present specification may comprise a chelator that comprises a polyidentate that does not comprise a soft base, said chelator that comprises a polyidentate that does not comprise a soft base may be present in an amount of about 0.01% to about 50%, or about 0.1% to about 5%, based on the total weight of the agglomerate. In one aspect, said chelating polyidentate that does not comprise a soft base may comprise a material selected from the group consisting of acrylic polymers, hydroxy carboxylic acids (e.g., tartaric acid, citric acid, malic acid, glyconic acid, ferulic acid, lactic acid, glucuronic acid);

1,3-diketones (for example, ascorbic acid), polyphosphates (for example, citric acid, methyl glutamic dicarboxy acid, malic acid, nitrile triacetic acid, oxalic acid, phosphoric acid, succinic acid), and combinations thereof.

In one aspect, the chelators that are useful in the beneficial agent release compositions disclosed in this specification can comprise a peptide and / or a polar amino acid. The polar amino acid can include arginine, asparagine, aspartic acid, glutamic acid, glutamine, lysine, and combinations thereof.

In one aspect, any of the benefit agent release compositions disclosed in this specification can

10/57 comprise a chelator that is acceptable for use in products that are edible by humans and / or other animals. Such chelators include polyphosphates (for example, sodium tripolyphosphate, hexametaphosphoric acid, sodium pyrophosphate, sodium pyrophosphate, tetrasodium pyrophosphate, sodium hexametapostate, sodium metaphosphate); amino carboxylic acids (eg ethylene diaminetetraacetic acid (EDTA), 1,2-bis (2-amino-phenoxy) ethane-N, N, N'N'-tetra-acetic acid (EGTA), ethylene bis (oxyethylene nitrile) - tetraacetic (BAPTA), N- (hydroxy ethyl) -ethylenediamine triacetic acid (HEDTA), diethylene triaminopentaacetic acid (DTPA), N-dihydroxy ethylglycine (2-HxG), ethyl bis (hydroxy phenyl glycine) ( EHPG), glutamic acid, aspartic acid, glycine, lysine); 1,3-diketones (for example, ascorbic acid); hydroxy carboxylic acids (for example, tartaric acid, citric acid, malic acid, glyconic acid, ferulic acid, lactic acid, glucuronic acid); polyamines (for example, diethylenetriamine, triethylene triamine); aminoalcohols (for example, triethanol amine, N-hydroxy ethyl ethylene diamine, amino ethyl ethanolamine (AEEA); polymers (e.g. polyethylene imines, polymethacryloyl acetone, poly (p-vinylbenzyl imino diacetic acid)), phosphonic acids and bisphosphonic acids ( for example, nitrile trimethylene phosphonic acid, ethylenediamine tetradiethylene phosphonic acid), hydroxy ethylidene diphosphonic acid), and mixtures thereof.

In one aspect of the aforementioned benefit agent release composition, said plasticizer may comprise a material selected from the group consisting of water; alcohols including glycerol, ethanol and / or propane-1-diol; glycols including polyethylene glycols, for example, polyethylene glycols with a molecular weight (weight average) less than 600 Da or even from about 600 Da to about 200 Da; fatty acids; petroleum derivatives including paraffins, petrolatum and / or mineral oils; vegetable oils, and mixtures thereof; in one aspect, said plasticizer may comprise a material selected from the group consisting of water and alcohols and mixtures thereof; in one aspect, said plasticizer may comprise a material selected from the group consisting of water and glycerol and mixtures thereof; in one aspect, said plasticizer may contain water.

In one aspect of the aforementioned benefit agent release composition, said binder may comprise a material selected from the group consisting of celluloses including methyl cellulose, including CMC, and derivatives thereof; alginate and derivatives of these substances; starches; polyvinyl alcohols; polyethylene oxide; polyvinyl pyrrolidone; polysaccharides including chitosan and / or natural gums including carrageenan; polyacrylates including cross-linked polyacrylates; waxes; polyethylene glycols, for example, polyethylene glycols with a molecular weight (weight average) greater than 4000 Da or even from about 4000 Da to about 15,000 Da; alcohol ethoxylates; surfactants and mixtures thereof; in one aspect, said binder may comprise a material selected from the group consisting of celluloses including methyl cellulose, including CMC, and derivatives of those substances; alginate and derivatives of these substances; starches; polyvinyl alcohols; polysaccharides including chitosan and / or natural gums including carrageenan; polyacrylates including cross-linked polyacrylates; polyethylene glycols, for example, polyethylene glycols with a molecular weight (weight average) greater than 4000 Da or even from about 4000 Da to about 15,000 Da, and mixtures thereof; in one aspect said binder may comprise a material selected from the group consisting of celluloses including methyl cellulose, including CMC, and derivatives of those substances; alginate and derivatives of these substances; starches; polyvinyl alcohols; polyacrylates including cross-linked polyacrylates; polyethylene glycols, for example, polyethylene glycols with a molecular weight (weight average) greater than 4000 Da or even from about 4000 Da to about 15,000 Da, and mixtures thereof; in one aspect said binder may comprise a material selected from the group consisting of celluloses including methyl cellulose, including CMC; polyacrylates including cross-linked polyacrylates; polyethylene glycols, for example, polyethylene glycols with a molecular weight (weight average) greater than 4000 Da or even from about 4000 Da to about 15,000 Da, and mixtures thereof.

In one aspect of the composition for the release of

As mentioned above, said dust removal agent may comprise a material selected from the group consisting of silicas; zeolites; amorphous aluminum silicates; clays; starches; celluloses; water-soluble salts including sodium chloride, sodium sulfate, magnesium sulfate and / or sodium carbonate; polysaccharides including sugars, and mixtures thereof; in one aspect, the dusting agent may comprise a material selected from the group consisting of silicas; aluminosilicates including zeolite; clays; starches; celluloses; polysaccharides including sugars, and mixtures thereof; in one aspect, said dusting agent may comprise a material selected from the group consisting of silicas; aluminosilicates including zeolite; clays; starches; celluloses, and mixtures thereof; in one aspect, said dusting agent may comprise a material selected from the group consisting of silicas; aluminosilicates including zeolite; clays, and mixtures thereof.

In any aspect of the aforementioned beneficial agent release compositions, said agglomerate, extruded and / or particulate may have a characteristic dimension of about 100 microns to about 3000 microns, from about 200 microns to about 2500 microns, from about 300 microns to about 2000 microns, from about 400 microns to about 1400 microns, or even from about 500 microns to about 1200 microns, and for said agglomerates and particulates, this characteristic dimension is the size particle average of said agglomerates and particulates and said characteristic dimension of said extruded is the average diameter of said extruded.

Composition for Releasing Beneficial Agents - Aggregate / Particle / Extruded

Compositions for release of beneficial agent can be produced according to the examples in this specification and / or through processes that can comprise:

The. combining an encapsulated benefit agent in one aspect, said encapsulated benefit agent comprising a core and a housing encapsulating said core, said core and / or housing

The encapsulated benefit agent comprises chelating agent; a chelator, a plasticizer, and a binder to form a mixture;

B. combining said mixture with said dusting agent to form a material, and

ç. removing a sufficient amount of said plasticizer from said material to produce a product comprising, based on the total weight of the product, from about 1% to about 50%, from about 2% to about 45%, from about 3% to about 40%, from about 4% to about 37%, from about 5% to about 35%, or even from about 6% to about 30% of plasticizer.

Encapsulated benefit agent

Applicants recognized that the problems associated with incorporating an encapsulated benefit agent into a dry product, including premature rupture of the encapsulated carcass during the incorporation process, can be minimized when the encapsulated benefit agent is further processed and incorporated into a agglomerate that can then be added to a consumer product as a dry consumer product that can be a particulate, powder or other essentially dry form.

The wall materials of the useful encapsulates may comprise materials selected from the group consisting of polyethylenes, polyamides, polystyrenes, polyisoprene, polycarbonates, polyesters, polyacrylates, polyureas, polyurethanes, polyolefins, polysaccharides, epoxy resins, vinyl polyesters, and mixtures of themselves. In one aspect, useful wall materials include materials that are sufficiently impervious to the core material and materials in the environment in which the encapsulated benefit agent will be employed, to allow the benefit to be released to be obtained. Suitable waterproof wall materials include materials selected from the group consisting of reaction products of one or more amines with one or more aldehydes, such as urea crosslinked with formaldehyde or gluteraldehyde, melamine crosslinked with formaldehyde; gelatin-polyphosphate coacervates optionally cross-linked with gluteraldehyde; coacervates of

14/57 gum arabic; cross-linked silicone fluids; polyamine reacted with polyisocyanates and mixtures thereof. In one aspect, the wall material may comprise melamine crosslinked with formaldehyde.

The core of the encapsulated benefit agent can comprise raw material for perfume, silicone oils, waxes, hydrocarbons, higher fatty acids, essential oils, lipids, skin cooling agents, vitamins, sunscreens, antioxidants, glycerin, catalysts, bleaching particles , silicon dioxide particles, unpleasant odor reducing agents, odor controlling materials, chelating agents, antistatic agents, softening agents, insect and moth repellent agents, colorants, antioxidants, chelating agents, incorporating agents, trim and shape control agents , smoothing agents, wrinkle control agents, sanitizing agents, disinfectant agents, germ control agents, mold control agents, mold control agents, antiviral agents, drying agents, stain resistance agents, dirt release, cloth renewing agents and f extension agents rescor, chlorine-based bleach odor control agents, pigment fixatives, color transfer inhibitors, color maintenance agents, optical brighteners, color restoration / rejuvenation agents, anti-fading agents, whitening enhancers , anti-abrasion agents, wear resistance agents, cloth integrity agents, anti-wear agents, anti-foaming agents, defoaming and defoaming agents, UV protection agents for cloths and skin, sun-bleaching inhibitors, agents antiallergens, enzymes, waterproofing agents, cloth comfort agents, shrink resistance agents, stretch resistance agents, extension recovery agents, skin treatment agents, glycerin, and natural actives such as aloe vera, vitamin E, butter shea, cocoa butter, and the like, bleach, bactericidal actives, anti-perspirant actives, cationic polyesters and mixtures thereof. In one aspect, said perfume raw material can be selected from the group consisting of alcohols, ketones, aldehyde 15/57, esters, ethers, alkylene nitriles. In one aspect, the core material may comprise a perfume. In one aspect, said perfume may comprise a perfume raw material selected from the group consisting of alcohols, ketones, aldehydes, esters, ethers, nitrile alkenes and 5 mixtures thereof. In one aspect, said perfume may comprise a perfume raw material selected from the group consisting of perfume raw materials which have a boiling point (PE) of less than about 250 ° C and a ClogP of less than about 3, perfume raw materials that have a PE greater than about 250 ° C and a ClogP greater than about 10 3, perfume raw materials that have a PE greater than about 250 ° C and a ClogP less than about 3 , raw materials for perfume that have a PE less than about 250 ° C and a ClogP greater than about 3 and mixtures thereof. Perfume raw materials that have a PE boiling point of less than about 250 ° C and a ClogP of less than about 3 are known as perfume raw materials in Quadrant I, perfume raw materials that have a PE greater than about 250 ° C and a ClogP greater than about 3 are known as perfume raw materials for Quadrant IV, perfume raw materials that have a PE greater than about 250 ° C and a ClogP less than about 3 are known as 20 perfume raw materials in Quadrant II, perfume raw materials that have a PE of less than about 250 ° C and ClogP greater than about 3 are known as perfume raw materials in Quadrant III. In one aspect, said perfume may comprise a perfume raw material that has a P.E. less than about 250 ° C. In one aspect, said perfume 25 may comprise a perfume raw material selected from the group consisting of Quadrant I, II, III perfume raw materials and mixtures thereof. In one aspect, said perfume may comprise a perfume raw material from Quadrant III. Suitable perfume raw materials from Quadrants I, II, III and IV are disclosed in U.S. Patent No. 6,869,923 B1.

In one aspect, said perfume may comprise a quadrant IV perfume raw material. Without sticking to the theory, it is believed that

16/57 such quadrant IV perfume raw materials can optimize the perfume odor balance. Said perfume may comprise, based on the total weight of the perfume, less than about 30%, less than about 20%, or even less than about 15% of said perfume raw material for Quadrant IV.

In one respect, useful perfumes and / or flavorings include those mentioned in the following table:

3- (METHYLTH) HEXANOL

1-BUTANOL, 2-METHYL-

1-BUTANOL, 3-METHYL-

1-ETHYL ACETATE PROPII_A

1-HEXANOL, 2-ETHYL-

1-HEXENOL

1-METOXY-4-PROPENYLBENZENE

1-METHY BUTYL ACETATE

1-METHYL PROPYL ACETATE

1-OCTANOL

1- OCTEN-3-OL

2.4- DECADIENAL

2.4- DECADIENOATE

2.5- DIMETHYL-4-HYDROXY-3- (2H) -

FURANONA

2.5- DIMETHIL PIRAZINE

-2,5-DIMETHIL PIRAZINE

2.6 HEPTENAL DIMETHYL-5

2.6- DIMETHYL PIRAZINE -2,6-DIMETHYL PIRAZINE

2.6- NONADIENAL

2,6-NONADIENAL

2- FURANO ACETYL

2-ACETYL PYRIDINE

3-METHY BUTYL ACETATE

3-METHYL BUTYL-2-METHYL BUTYRATE

3-METHYLPROPANAL

3- METHYLTHIO-1-HEXANOL

4- ACETHOXY-2,5-DIMETHYL-3 (2H) FURANONE

4-CARVOMENTANOL

4-METHYL-4-MERCAPTO-2PENTANONE

4-METHYL-5-THIAZOL ETHANOL

4-METHYL ACETOPHENONE

4-TERPINOL

6-METHYL-5-HEPTENO-2-ONA

6-NONEN-1-OL

6-METIL HEPT-5-EN-2-ONA

A-KINAMIC AMIL ALDEHYDE

A-BISABOLENO

ACETAL

ACETALDEHYDE

ACETIC ACID

ACETIC ACID, 2-PHENYLETYL ESTER

ACETOPHENONE

ACETÓXI-FURANEOL (4-ACETÓXI2,5-DIMETIL- (2H) -FURANONA) ACETIL METHYL CARBINOL ACETIL PROPIONILA

17/57

-2-ACETYL PYRIDINE

2-ACETYL TIAZOLE

2-BUTENAL

2-ETHYL-1-HEXANOL

2-HEXANOL

2-ISOPROPYLA-4-METHYL THYZOLE 2-M ETOXY-3-M ETHYLPIRAZI NA -2-METHYXY-3-METHYLPIRAZINE 2-METHYXY-4-ALYL PHENOL 2-METHYPHOPHENOL

2-METHYL BUTANOL

2-METHY BUTYL ACETATE

2-METHYL PENTENOIC ACID (STRAWBERIFF)

2-METHYL PROPYL ACETATE 2-METHYL-1-PROPANOL 2-METHYL-3- (P-METHYL PHENYL) PROPANAL

2-METHYL-4-PROPIL-1,3-OXATIANO 2-METHYLBUTANOIC ACID 2-METHYL BUTYL ACETATE 2-METHYL BUTYRIC ACID 2-METHYL PENT-2-ENAL (TRANS) 2-METHYL PROPANOL

2-METHYL PROPYL CAPROATE (ISOBUTYL CAPROATE) 2-METHYL TETRA-HYDROFURAN-3ONE

2- PHENYLETANOL

2-PROPENOIC ACID, ETHYL ESTER

2-PROPENYL HEXANOATE

3- (METHYLTH) -1 -PROPANOL 3,4-DI-HYDROCUMARINE 3,5,5-TRIMETHILE HEXANAL

ALDEHYDE C12

ALDEHYDE C16

ALILA CAPROATE ALILA CYCLE-HEXAN PRIOPIONATE

ALPHA-IRONA

ALPHA-IONONE

ALPHA-IRONA

ALFA-METHYL ACETATE BENZILA ALFA-PINENO

ALPHA-TERPINOL

AMBRETOLIDE

A-METHYL BENZILA PROPIONATE

AMYLA ACETATE

CINAMIC AMIL ALDEHYDE

AMILA ISOVALERATE

AMILA PROPIONATE

AMILA VALERATE

ANISIC ALDEHYDE

ANISYL ACETATE

ANISYL ACETONE

A-PINENO

ARUSCOL FIRMENICH B-CARIOPHENYLENE

BENZALDEHYDE

BENZILA ACETATE

BENZILIC ALCOHOL

BENZILIC ALCOHOL

BENZIL CINAMATO PROPIONATO DE BENZILA BETA DAMASCENONA

18/57

3-METLL-BUTANAL BETA-DAMASCENONE

3-METHYL BUTYL ACETATE BETA DAMASCONA

3-METHYL BUTANOL BETA-IONONE

BETA-PINENO ETHYL BUTYRATE

BUTANAL ETHYL CAPRILATE (OCTANOATE)

BUTANOIC ACID. 2-METHIL-. ETHYL ETHYL CINAMATE

ESTER

BUTANOIC ACID, BUTANOL METHYSTER

BUTYL ACETATE BUTYL BUTYRATE BUTYL CAPROATE BUTYL HEXANOATE BUTYL PROPIONATE BUTYLIC ACID CAPROIC ACID (HEXANOIC) CAPRILLIC ACID CARIOPHENYLENE ALUMINUM CINAMIC ACID

CIS-3-HEXENOL CIS-3-HEXENIL BUTYRATE 2METHYL

CIS-3-HEXENYL ACETATE CIS-3-HEXENYL ACETATE

CIS-3-HEXENYL BUTYRATE CIS-3-HEXENYL FORMIATE CIS-3-HEXENYL LACTATE CIS-3-HEXENYL-2METHYL BUTYRATE

CIS-5OCTENYL PROPRIONATE

CIS-6-NONENOL CIS-JASMONA

ETHYL DODECANOATE

ETHYL HEXANOATE

ETHYL ISOBUTYRATE

ETHYL ISOVALERATE

ETHYL LACTATE

ETHYL MALTOL

ETHYL MALTOL®

ETHYL NONANOATE ETHYL OCTANOATE ETHYL OCTANOATE ETHYL OXY-HYDRATE ETHYL PELARGONATE (NONAOATE)

ETHYL PROPIONATE

ETHYL PROPIONATE

ETHYL VALERATE

3-ETHOXY-4-HYDROXY BENZALDEHYDE (ETHYL VANILLIN)

ETHYL (METHYLTH) ACETATE ETHYL-2,5- (2,6) DIMETHYL PIRAZINE ETHYL-2-METHYL BUTYRATE ETHYL-3 (METHYL) PROPRIONATE

ETHYL-3-METHYL BUTYRATE

ETHYL-3-METHYL BUTYRATE ETHYL PHENYL ACETATE

19/57

CIS-TO-MIND-8-TIOL-3-ONA (TIOMENTONE)

CITRAL

CITRONELOL

CITRONELOL

CITRONELILE FORMIATE CITRONELILE PROPIANOATE CYCLOTHE ALDEHYDE CYCLOTENE®

CIMENO

DAMASCENONE

DECANAL

DECANOIC ACID

DECANOL DELTA-DODECALACTONA DELTA DECALACTONA DELTA OCTALACTONA DELTA UNDECALACTONA DELTA-DODECALACTONA DIACETILA

DIACETHIL

DIMETHYL ANTHANYLATE D-LIMONENE DIMETHYL SULPHIDE

DODECANAL

DODECANOIC ACID ETHYL ACETATE ETHYL PENTANOATE ETHYL PROPANOATE 3 (METHYL)

ETHYL ACETOACETATE ETHYL ACRYLATE ETHYL ANTHRANILATE ETHYL BENZOATE IRISON-ALFA

ISOAMYL ACETATE ISOAMYL ALCOHOL

FURANEOL®

SUPER GALBANOLENE

HEPTALACTONE RANGE

HEXALACTONE RANGE

NONALACTONE RANGE

OCTALACTONE RANGE

RANGE UNDECALACTONE GAMA-TERPINENE RANGE-DEACLACTONE GAMA-DODECALACTONE GAMA-METHYL IONONE

GERANIOL

GERANILLA ACETATE

GERANILLA BUTYRATE

GERANILLA FORMIATE GERANILLA PROPRIONATE GLACIAL ACETIC G-TERPINENE

HEDIONA

HELIOTROPINE

HEXANAL

HEXANOIC ACID

HEXANOIC ACID, HEXANOL METHYL ESTER

HEXENIL HEXANOATE

HEXYL ACETATE

HEXYL ALCOHOL

HEXILA BUTYRATE

HEXYL VALERATE

HEXYL-2-METHYL BUTYRATE

CITRONELAL HYDROXY

ACETOPHENONE HYDROXY

PALMITIC ACID

PARA-CIMENO

PENTANOIC ACID

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ISOAMYL BUTYRATE ISOBORNILE ACETATE ISOBUTYL ACETATE ISOBUTYL ACETATE ISOBUTYL BUTENOATE ISOBUTYL CAPROATE ISOBUTYL ISOBUTYL ACETATE PHENYL ISOLOPYL-ISOLOPHYL-ISOLOPHYL-ISOLOPHYL-ISOLOPHYL-ISOLOPHYL-ISOLOPHYL-ISOLYLOPHYL

LINALOL OXIDE LINALYL ACETATE LINALYL CINAMATE LINALYL PROPIONATE LINALYL-3-METHYL BUTYRATE L-MENTONE

MALTOL MALTOL®

MELONAL® (EVEN THAT A18) METHYLENE FENIL BUTANONE METHYL PROPRIONATE 3 (METHYL)

METHYL AMYL KETONE METHYL ANTHRANYLATE METHYL BUTYRATE METHYL METHYL CARBONATE METHYL HEPTYL METHYL HEPTYL KETONE METHYL HEXYL KETONI METHYL THYLUTYL

METHY VINYL TIAZOLE

PHENOXY PROPIONATE ETHYL FENY ACETALDEHYDE PHENYLETANOL

PHENYLETYL ACETATE PHENYL ETHYL TIGLATE PHENYL ETHYL ACETATE PHENYL ETHYL METHYL ETHER P-MENTA-3-ONA-8-THYOLACETATE PRENOL

PRENYL ACETATE

PROPANOL

PROPIONIC ACID

PROPYL ACETATE

GLYPOL PROPYLENE

PULEGONO

SULFOX FIRMENICH

TERPENYL ACETATE

THIAZOL, 2-ETHYL-4-METHYLTHIAZOLE, 4-ETHYL-2-PROPYLATIOMENTONE

TIOMENTONE ACETATE

TRANS-2-CIS-6-NONADIENO-1-OL TRANS-2-DECEN-1-AL

TRANS-2-HEXENAL

TRANS-2-HEXENAL

TRANS-2-HEXANOIC ACID TRANS-2-HEXENOL

TRANS-2-HEXENILA ACETATE TRANS-3-HEXANOIC ACID TRIACETIN

-TRI-METHYL OXAZOLE

TRI-METIL OXAZOL

TRIMETIL PIRAZINA

-TRIMETHIL PIRAZINE

4-HYDROXY-3-METHYXY BENZALDEHYDE (VANILLINA)

2Μ57

-METHYL VINYL TIAZOL MIRCEN

METHYL-2- (METHYLTH) ACETATE NATACTONE FIMENICH METHYL-2-BUTYRATE METHYL N-BUTYRALDEHYDE METHYL-2-OCTINOATE NEROL

NERILA TIO METHYL-3-METHYL ACETATE

METHYL-3-NONENATE

METHYL PHENYL HEXENAL (COCAL®) METHYL BUTYRATE METHYLTHE OCTYL ACETATE OXANONE®

NONANOL

N-VALERALDEHYDE

OCIMENO (TRANS)

OCTANAL

OCTANOIC ACID

Perfumes suitable for use in the present invention include the following:

CAS P&G Name Chemical name 7540-51-4 BARANOL (-) - Citronelol 2216-51-5 MENTHOL (-)-Menthol 16356-11-9 SUPER GALBANOLENE (3E, 5Z) -1,3,5-Undecatriene 557-48-2 E, Z-2, 6-NONADIENO-1-AL FCC (E) -2, (Z) -6-Nonadienal 3239-35-8 TANGERINOL (E) -5-Tangerinol 3239-37-0 TANGERINOL (Z) -5-Tangerinol 6790-58-5 AMBROFIX [3aR- (3aa, 5ab, 9aa, 9bb)] dodecahydro-3a, 6,6,9atetramethyl naphtho [2,1-b] furan 13851-11-1 FENCHILA / SUPER ACETATE 1,3,3-trimethyl-2norbornanyl acetate 80118-06-5 ISOPENTIRATE 1,3-dimethyl-3butenyl isobutyrate 112-45-8 UNDECYLENIC ALDEHYDE 10-Undecenal 53179-04-7 FLORIDILE 10-undecenenitrile 112-30-1 RHODALIONE 1-Decanol 2442-10-6 AMIL ACETATE VINYL CARBINILE 1-octen-3-yl acetate 106-02-5 CYCLE- ΡΕΝΤΑ DECANOLIDED 1-Oxacyclo hexadecan-2-one 128-51-8 NOPILE ACETATE 1 R acetate - (-) - nopila

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CAS P&G Name Chemical name 37172-02-4 DI-HIDRO AMBRATO 2- (sec.butil) -1vinylcyclohexyl acetate 68039-49-6 CICLALC 2,4-dimethyl-3-cyclohexene-1 carboxy aldehyde 141-13-9 ADOXAL 2,6,10-trimethyl-undec-9-enal 13254-34-7 DIMETHIL-2 6-HEPTAN-2-OL 2,6-dimethyl-2-heptanol 7786-44-9 2,6-NONADIEN-1-OL 2,6-Nonadien-1-ol 23696-85-7 DAMASCENONE 2-Buten-1-one, 1- (2,6,6- trimethyl-1,3-cyclohexadien-1-yl) - 28219-61-6 DARTANOL 2-ethyl-4- (2,2,3-trimethylcyclopent- 3-en I-1) -2-buten-1-ol 137-03-1 FLEURAMONA 2-heptyl cyclopentanone 24168-70-5 ISOBUTY PIRAZINE METOXY @ 0.1% MPG FP246 2-methoxy-3- (1-methyl propyl) pyrazine 1205-17-0 HELIONAL 2-methyl-3- (3,4-methylene dioxiphenyl) -propanal 543-39-5 MIRCENOL SUPER 13.2193 (CONF.-IFF) 2-methyl-6-methylene-7-octen-2-ol 110-41-8 METHYL NONYL ACETALDEHYDE 2-methylundecanal 2463-53-8 2 NONEN-1-AL 2-Nonen-1-al 4819-67-4 DELPHONE 2-pentyl cyclopentanone 103-60-6 ETHYL PHENOXY ISOBUTYRATE Phenoxy ethyl 2-isobutyrate 103-45-7 PHENYLETHYL ACETATE 2-Phenyl ethyl acetate 14765-30-1 2-SEC-BUTIL CICLOHEXANONA 2-sec.butil cyclohexanone 6784-13-0 LIMINAL 955374 3- (4-methyl cyclohex-3-en-1-yl) butyraldehyde 7775-00-0 CYCLEMAX 3- (p-isopropyl phenyl) propionaldehyde 58430-94-7 ISONONYL ACETATE 3,5,5-trimethyl hexyl acetate 106-21-8 DIMETHYL OCTANOL 3,7-dimethyl-1-octanol 67801-20-1 EBANOL 3-methyl-5- (2,2,3-trimethyl-3cyclopenten-1-yl) pent-4-en-2ol 55066-49-4 MEFRANAL 3-Methyl 1-5-phen i-1-pentanal

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CAS P&G Name Chemical name 20407-84-5 MANDARINE ALDEHYDE 10% IN CITRATE 3-Nonylacrolein 18127-01-0 BOURGEONAL 4- (1,1-Dimethyl ethyl) benzene propanal 18096-62-3 INDOFLOR CRIST. 4.4a, 5.9b-tetrahydroindene [1,2-d] -1,3-dioxin 13171-00-1 ALMÍSCAR INDANONA 4-Acetyl-6-t-buti I-1,1-dimethyl indane 4621-04-9 ROSELEA 4-lsopropylcyclohexanol 122-00-9 PARAMETHYL ACETOPHENONE 4-Methyl acetophenone 562-74-3 TERPINENOL-4 4-Terpinenol 32210-23-4 4-BUTYL ACETATE CLCLO-HEXILA TERTIARY Tertiary butyl cyclohexyl 4-acetate 16587-71-6 ORIVONA 4-tert-amyl cyclohexanone 37609-25-9 5-CYCLE-HEXADECEN-1- ONA 5-cyclohexadecenone 22457-23-4 STEMONA 5-methyl-3-heptanone oxime 32764-98-0 JASMOLACTONE 6- (Z, 3-pentenyl) -tetrahydro- (2H) -pyranone-2 33885-51-7 PIN ACETALDEHYDE 6,6-dimethyl-2-norpinene-2propionaldehyde 70214-77-6 NONADIL 6,8-diethyl-2-nonanol 65442-31-1 ISOBUTY QUINOLINE 6-isobutyl quinoline 135-79-5 ISOPROPIL QUINOLINA 6-isopropyl quinoline 91-62-3 PARAMETHIN QUINOLINE 6-methyl quinoline 1506-02-1 AMTOLIDE 7-acetyl-1,1,3,4,4,6-hexamethyl tetralin 84697-09-6 ACALEA TBHQ Calm down 100-06-1 PARAMETÓXI ACETOPH / BENZ / SALIC MX Acetoanisole 98-86-2 ACETOPHENONE Acetophenone 67634-00-8 ALYL AMILA GLYCOLATE Allyl amyl glycolate 123-68-2 ALILA CAPROATE Alila Caproate 2705-87-5 CYCLE-HEXAN ALILA PROPIONATE Alyl cyclohexyl proprionate

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CAS P&G Name Chemical name 142-19-8 ALILA HEPTANOATE, 97 +% FCC Alila heptanoate 7493-74-5 ALILA'S PHENOXY ACETATE Allyl phenoxy acetate 67634-15-5 FLORALOZONE alpha, alpha-dimethyl-p-ethyl phenyl propanal 122-40-7 CINAMIC AMIL ALDEHYDE alpha-amyl cinnamaldehyde 60763-41-9 ACETAL DIETYL OF KINAMIC AMIL ALDEHYDE alpha-amyl cinnamaldehyde diethyl acetal 17627-44-0 BISABOLEN alpha-bisabolene 24720-09-0 ALFA DAMASCONA Alpha Damascona 502-61-4 BISABOLEN alpha-Farnesene 101-86-0 KINAMIC HEXY ALDEHYDE alpha-Hexyl cinnamaldehyde 127-41-3 IONONA AB alpha-lonona 79-69-6 REFINED ALPHA IRON alpha-lrona 127-51-5 IONONE METHY RANGE alpha-lsometillionone 98-55-5 ALFATERPINOL alpha-terpinol 80-26-2 LINDENIL- ACETATE alpha-terpinyl acetate 2050-08-0 DEAMIL SALICYLATE amyl salicylate 189440-77-5 ANAPEAR 8753453 Anapear 104-21-2 DEANISILA ACETATE Anisyl acetate 25225-08-5 AFERMATO Afermato 89-43-0 AURANTIOL Aurantiol 362467-67-2 AZURONA 10 0015573 Azurona 100-52-7 BENZALDEHYDE Benzaldehyde 119-61-9 BENZOFENONE Benzophenone 140-11-4 BENZILA ACETATE Benzyl acetate 100-51-6 BENZILIC ALCOHOL Benzilic alcohol 120-51-4 BENZIL BENZOATO Benzyl benzoate 103-37-7 BENZILA BUTYRATE Benzyl Butyrate 103-41-3 BENZIL CINAMATO Benzyl cinnamate 100-86-7 DIMETHYL BENZIL CARBINOL Dimethyl benzyl carbinol 103-28-6 BENZILA ISOBUTYRATE Benzyl isobutyrate 122-63-4 BENZILA PROPIONATE Benzyl Propionate 118-58-1 BENZILA SALICILATE Benzyl salicylate 2550-26-7 BENZIL ACETONA Benzylacetone

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CAS P&G Name Chemical name 103-05-9 FENIL ETIL DIMETIL CARBINOL Benzyl-ter-butanol 23267-57-4 IONONE EPOXIDE, BETA Beta-epoxide ionone 103-64-0 BROMOSTIROL Beta-bromostirol 87-44-5 EXTRA CARIOPHENYLENE Beta-karyophylene 23726-91-2 DAMASCONE BETA Beta-damascone (E configuration) 18794-84-8 BISABOLEN Beta-farnesene 185429-83-8 GEORGYWOOD (CONF.-GIV) beta-Georgywood 14901-07-6 BETA-IONONA 97 +% FCC (CONF.-ALDRICH) beta-ionone 123-35-3 MIRCENE beta-mycrene 127-91-3 BETA-PINENO beta-pinene 72429-08-4 BIGARADE OXIDE Bigarade oxide 495-62-5 BISABOLEN Bisabolene 58567-11-6 BOISAMBRENO FORTE (S 506) Boisambreno forte 24717-86-0 ABIERATO CN (C SYN) Bornyl isobutyrate 3155-71-3 BORONAL Boronal 72089-08-8 BRAHMANOL F / 3/071130 Brahmanol 75147-23-8 BUCCOXIME Buccoxime 136-60-7 BUTYL BENZOATE Butyl benzoate 128-37-0 BUTILED TOLUENE HYDROXY Butylated toluene hydroxy 79-92-5 CAMPHEN Canfeno 76-22-2 CAMPAIGN GUM Camphor 5462-06-6 CANTHOXAL (03-0952) Canthoxal 112-31-2 DECIL ALDEHYDE Capraldehyde 111-87-5 OCTYL ALCOHOL Caprylic alcohol 124-13-0 OCTIL ALDEHYDE Caprylic aldehyde 33704-61-9 CASHMERAN Cashmeran 77-53-2 CEDROL Cedrol 77-54-3 CEDAC Cedril acetate 19870-74-7 METHYL ETHER OF CEDRILE Cedril methyl ether

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CAS P&G Name Chemical name 3720-16-9 LIVESCONA Celery ketone 6707-60-4 12OXA- HEXADECECANOLID Cervolida 79-78-7 HEXALON Ketone V 88-04-0 4-CHLORINE 3.5 XYLENOL Chloroxylenol 1885-38-7 CINAMALVA Cinnamon 104-54-1 CINAMIC ALCOHOL Cinnamic alcohol 104-55-2 KINAMIC ALDEHYDE Cinnamic aldehyde 103-54-8 CINAMYL ACETATE Cinamyl acetate 53046-97-2 3.6-NONADIEN-1-OL cis-3, cis-6-nonadienol 928-96-1 BETA HEXENOL RANGE cis-3-hexen-1-ol 53398-85-9 CIS-3HEXENIL ALPHA BUTYRATE Cis-3-hexenyl 2-methyl butyrate 3681-71-8 CIS-3- ACETATE HEXENILA Cis-3-hexenyl acetate 25152-85-6 CIS-3HEXENILLA BENZOATE Cis-3-hexenyl benzoate 16491-36-4 CIS-3HEXENIL BUTYRATE Cis-3-hexenyl butyrate 65405-77-8 CIS-3HEXENILA SALICYLATE cis-3-hexenyl salicylate 67883-79-8 CIS-3HEXENIL TIGLATE Cis-3-hexenyl tiglate 36508-31-3 CIS-ISO-AMBRETOLIDE Cis-iso-ambretolide 488-10-8 CIS JASMONA cis-jasmine 5392-40-5 CITRAL Citral 7549-37-3 CITRAL DIMETHIL ACETAL Citral dimethyl acetal 106-23-0 CITRONELAL Citronelal 106-22-9 CITRONELOL Citronelol 150-84-5 CITRONELILLA ACETATE Citronellar acetate 105-85-1 CITRONELILLA FORMIATE Citronellate formate 51566-62-2 BARANIL NITRILA Citronellil nitrile 141-14-0 CITRONELILLA PROPIONATE Citronellyl propionate

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CAS P&G Name Chemical name 7492-67-3 CLTRONELYL OXYACETALDEHYDE Citronellyl oxyacetaldehyde 97384-48-0 CITROWANIL B Citrowanil B 6819-19-8 CITRILLA ACETATE Citrile acetate 83926-73-2 CORANOL (CONF.-FIRM) Coranol 91-64-5 CUMARINA Coumarina 122-03-2 CUMINICAL ALDEHYDE Cuminaldehyde 13816-33-6 CITROEN NITRIL Cuminyl nitrile 67634-20-2 CYCLABUTE Cyclabute 103-95-7 CIMAL Cyclamen aldehyde 68991-97-9 MELAFLEUR MO9962 Cyclemone A 54982-83-1 ZENOLIDE Cyclic ethylene dodecanedioate 113889-23-9 CYCLEBUTANATE 081145 Cyclobutanate 68901-15-5 CYCLOGALBANATE Cyclogalbanate 22471-55-2 THESARON Cyclohexane carboxylic acid, 2,2,6-trimethyl-, ethyl ester, (1R, 6S) -rel- 25485-88-5 CYCLEHEXYL SALICYLATE Cyclohexyl salicylate 21722-83-8 CYCLEHEXYL ETHYL ACETATE Cyclohexylethyl acetate 84560-00-9 CYCLOPENTOL Cyclopentol 40203-73-4 CYCLOPIDENE 937160 Cyclopentyl ideneacetic acid, methyl ester 68039-69-0 DATILATE Datylate 5454-19-3 N-DECIL PROPIONATE Decyl proprionate 13019-22-2 ROSALVA Decylenic alcohol 57378-68-4 DELTA DAMASCONA Delta damascona 705-86-2 DECALACTONE delta-decalactone 82356-51-2 DELTA MUSCENONA 962191 delta-muscenone 431-03-8 DIACETHIL 0.1% IN DPG Diacetyl 105-53-3 DIETILE MALONATE Diethyl malonate 84-66-2 DIETHYL PHALATE Diethyl phthalate 37172-53-5 DI-HIDRO ISO JASMONATO Dihydro iso jasmonate

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CAS P&G Name Chemical name 498-81-7 DI-HYDROTERPINEOL Dihydro terpinol 17283-81-7 DI-HYDRO-BETA-IONONE Dihydro-beta-ionone 119-84-6 DI-HYDROCUMARINE Dihydrocoumarin 64001-15-6 DI-HIDRO CICLACET Dihydro cyclacet 2785-87-7 DI-HYDRO EUGENOL Dihydroeugenol 1128-08-1 DI-HYDROJASMONA Dihydrojasmona 18479-58-8 DIMIRCETOL Dihydromyrcenol 80-25-1 MENTANILLA ACETATE Dihydro terpinyl acetate 85-91-6 DIMETHYL ANTRANILATE Dimethyl anthranylate 151-05-3 DIMETHYL BENZYL CARBINYL ACETATE Dimethyl benzyl carbinyl acetate 10094-34-5 DIMETHYL BENZIL CARBINILE BUTYRATE Dimethyl benzyl carbinyl butyrate 103-05-9 FENIL ETIL DIMETIL CARBINOL Dimethyl phenyl ethyl carbinol 138-86-3 DIPENTENE Dipentene 101-81-5 DIPHENYLMETAN Diphenyl methane 101-84-8 DIPHENYL OXIDE Diphenyl oxide 25265-71-8 ABSOLUTE VANILLA 50 DPG 99FP / 1133 (C-FR) Dipropylene glycol 89-48-5 MINT ACETATE 620020 menti di acetate 2556-10-7 BODY OF JACINTO 08- 8735 Efetaal 40910-49-4 STRONG ELINTAAL elintaal 140-67-0 ESTRAGOL EX BADIANE Estragol 6413-10-1 690965 JASMAPRUNAT Ethyl acetate 2-methyl-1,3dioxolane-2 7452-79-1 ETHYL-2-METHYL BUTYRATE Ethyl 2-methyl butyrate 101-97-3 ETHYL PHENYL ACETATE Ethyl 2-phenyl acetate 5405-41-4 ETHYL-3HYDROXY BUTYRATE Ethyl-3-hydroxy butyrate 121-39-1 FENIL ETHYL GLYCIDATE Ethyl 3-phenylglycidate 141-78-6 ETHYL ACETATE Ethyl acetate 141-97-9 ETHYL ACETOACETATE Ethyl acetoacetate 589-98-0 OCTANOL-3 Ethyl amyl carbinol

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CAS P&G Name Chemical name 106-68-3 ETIL AMIL CETONA Ethyl amyl ketone 35044-59-8 ETHYL SAFRANATE Ethyl beta-safranate 105-54-4 ETHYL BUTYRATE Ethyl Butanoate 103-36-6 ETHYL CINAMATE Ethyl cinnamate 106-30-9 ETHYL ENANTATE Ethyl Heptoate 123-66-0 FCC ETHYL CAPROATE (GIVAUDAN) ethyl hexanoate 925-78-0 ETIL HEXIL KETONE Ethyl hexyl ketone 10339-55-6 ETHYL LINOLOL Ethyl linalool 4940-11-8 ETHYL MALTOL Ethyl Maltol 77-83-8 ETHYL METHYL PHENYL GLYCIDATE Ethyl methyl phenyl glycidate 105-37-3 ETHYL PROPIONATE Ethyl propionate 118-61-6 ETHYL SALICYLATE Ethyl salicylate 3025-30-7 2,4-E- DECADIENOATE TILA Trans-2, cis-4-ethyl decadienoate 121-32-4 ETHY VANILINE Ethyl vanillin 105-95-3 ETHYLENE BRASSILATE Ethylene Brassylate 470-82-6 EUCALIPTOL Eucalyptus 97-53-0 EUGENOL Eugenol 14595-54-1 EXALTENONE 942008 Exaltenone 4602-84-0 FARNESOL Farnesol 1632-73-1 PHENCHYL ALCOHOL Fenchyl alcohol 81925-81-7 FILBERTONA 1% IN TEC 736664 Filbertona G 134123-93-6 FLEURANIL Fleuranil 67634-26-8 FLORALATE 062960 Floralato 67634-25-7 FLORALATE 062960 Floralato 125109-85-5 FLORIDRAL Floridral 63500-71-0 FLOROL Florosa Q 80657-64-3 FRUIT Fruitato 35206-51-0 FRUTI NATO 611 400 Fructinate 69300-15-8 FRUTONILLA Frutonila 1222-05-5 GALAXOLIDE 50% CITROEN FLEX (C IFF) Galaxolid

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CAS P&G Name Chemical name 35087-49-1 DAMASCONE RANGE 944580 gamma-Damascone 706-14-9 DECALACTONE RANGE gamma-Decalactone 2305-05-7 DODECALACTONE gamma-dodecalactone 695-06-7 HEXALACTONE RANGE gamma-Hexalactone 104-61-0 NONALACTONE gamma-Nonalactone 104-50-7 FCC RANGE-OCTALACTONE gamma-Octalactone 104-67-6 UNDECALACTONE RANGE gamma-Undecalactone (racemic) 105-87-3 GERANILLA ACETATE Geranyl acetate 106-29-6 GERANILLA BUTYRATE Geranyl Butyrate 68133-79-9 APRITONE Geranyl cyclopentanone 105-86-2 GERANILLA FORMATION Geranyl formate 5146-66-7 CITRALVA PLUS Geranyl nitrile 102-22-7 FENIL GERANILLA ACETATE Geranyl acetate phenyl 57934-97-1 GIVESCONA Givescona 68901-32-6 GLYCOLIERRAL Glycolierral 68611-23-4 GRISALVA Grisalva 24237-00-1 GYRANE Gyrane 34902-57-3 100% HABANOLIDE Habanolid 120-57-0 HELIOTROPINE Heliotropine 40527-42-2 DIETYL ACETAL HELIOTROPINE Heliotropine diethyl acetal 141773-73-1 HELVETOLIDE 947650 Helvetolide 25304-14-7 HERBAC Herbac 116044-44-1 HERBANATE Herbanato 54546-26-8 HERBOXAN Herboxane 109-29-5 SILVANONE Cl Hexadecanolide 3681-73-0 HEXAROSA 947855 Hexarosa 10032-15-2 HEXYL-2METHYL BUTYRATE Hexyl-2-methyl butanoate 142-92-7 HEXYL ACETATE Hexyl acetate 2349-07-7 HEXILA ISOBUTYRATE Hexyl isobutyrate 111-13-7 METIL HEXIL KETONE Hexyl methyl ketone

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CAS P&G Name Chemical name 93-53-8 HYDROTHROPIC ALDEHYDE THERE Hydrotropic aldehyde 122-97-4 PROPYLIC FENY ALCOHOL Hydrokinyl alcohol 118562-73-5 HYDROXYAMBRAN Hydroxyambran 107-75-5 CITRONELAL HYDROXY Citronellal hydroxy 107-74-4 HYDROXIOL Hydroxy-citronelol 120-72-9 INDOL Indole 28645-51-4 AMBRETOLIDE Isoambretolid 123-92-2 AMIL- ACETATE (BLENDS OF ISOMERS) Isoamyl acetate 68683-20-5 ISOBERGAMATO Isobergamate 125-12-2 ISOBORNILE ACETATE Isobornyl acetate 66072-32-0 ISOBORNILA CYCLEHEXANOL Isobornyl cyclohexanol 2756-56-1 ISOBORNILE PROPIONATE Isobornyl propionate 110-19-0 NATURAL ISOBUTY ACETATE Isobutyl acetate 105-79-3 ISOBUTY CAPROATE Isobutyl Caproate 102-13-6 ISOBUTYL ACETATE PHENY Isobutyl phenyl acetate 87-19-4 ISOBUTYL SALICILATE Isobutyl salicylate 1335-66-6 ISO CITRAL CYCLE Isocyclocitral 68527-77-5 ISOCYCLOGERANIOL Isocyclogeraniol 39872-57-6 ISODAMASCONA N 3/055152 Isodamascona 54464-57-2 ISO CYCLONE E Iso-E Super 97-54-1 ISOEUGENOL Isoeugenol 93-29-8 ISOEUGENOL ACETATE Isougenol acetate 120-11-6 BENZILA ISOEUGENOL Benzoyl ether of isoeugenol 37677-14-8 ISOHEXENIL CYCLE-HEXENIL ALDEHYDE CARBOXY Carbooxy isohexenyl cyclohexenyl aldehyde 95-41-0 ISO JASMONA Iso Jasmine 491-07-6 ISO MENTONA Iso-mentone 123-51-3 ISOAMYLIC ALCOHOL 98 +% Isopentanol 106-27-4 AMILA BUTYRATE Isopentyl butyrate;

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CAS P&G Name Chemical name 66576-71-4 2-METHYL ISOPROPYL BUTYRATE Isopropyl 2-methyl butyrate 110-27-0 GALAXOLIDE 50 IPM Isopropyl myristate 89-79-2 ISOPULEGOL Isopulegol 18871-14-2 DIASMOL Jasmal 208041-98-9 JASMONITRILO 952906 Jasmonitrile 198404-98-7 JAVANOL (CONF.-GIV) Javanol 36306-87-3 LRG 182 Kephalis 75490-39-0 KHUSINIL Khusinil 86115-11-9 KOAVONE Koavone 92015-65-1 KOUMALACTONA 953320 Koumalactona 112-54-9 LAURIC ALDEHYDE Lauric aldehyde 2437-25-4 ALDINILA3881 (CONF.-SYN) Lauronitrile 6485-40-1 CARVONA LIGHT L-carvona 67633-96-9 LIFFAROME Liffarome 80-54-6 P.T. BUCINAL Lilial 7392-19-0 LRG 188 Limetol 61792-11-8 LEMONILA Limonila 78-70-6 LINALOL Linalol 115-95-7 LINALILLA ACETATE Linalyl acetate 126-64-7 LINALILA BENZOATE Linalyl benzoate 115-99-1 LINALILA FORMIATE Linalila formate 115-99-1 LINALILA FORMIATE Linalila formate 78-35-3 LINALILA ISOBUTYRATE Linalyl isobutyrate 144-39-8 LINALILA PROPIONATE Linalyl propionate 31906-04-4 LIRAL Liral 67845-30-1 MACEAL Maceal 103694-68-4 MAJANTOL Majantol 118-71-8 MALTOL Maltol 134769-33-8 MANDARIL600 135 Mandarin 13828-37-0 MAYOL Mayol 106-72-9 MELONAL Melonal 30772-79-3 FORMIL TRICICLODECANO Melozona 89-80-5 RACEMIC MENTONA Mint 3613-30-7 CITRONELAL METOXY PQ Citronelal Methoxy

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CAS P&G Name Chemical name 62439-41-2 ΜΕΤΟΧΙ MELONAL Melonal Methoxy 111-80-8 METHYL OCTIN CARBONATE Methyl 2-noninoate 111-12-6 METHYL HEPTINE CARBONATE Methyl 2-octinoate 28043-10-9 METHYL CYCLOGERANATE Methyl a-cyclogeranate 134-20-3 METHIL ANTRANILATE methyl anthranylate 91-51-0 P.T. BUCINAL METHY ANTRANILATE Methyl anthranilate / Lilial Schiff base 93-58-3 Methyl benzoate Methyl benzoate 93-08-3 METIL BETA-NAFTIL CETO- AT methyl beta-naphthyl ketone 103-26-4 METHIL CINAMATE Methyl cinnamate 24851-98-7 HEDIONA HC Methyl dihydrojasmonate 93-15-2 Methyl EUGENOL Methyl eugenol 93-16-3 METIL ISOEUGENOL Methyl isoeugenol 67633-95-8 METHYL LAUNDRY CETONE Methyl-Lavender Ketone 68141-17-3 METHYL NONYL ACETALDEHYDE DIMETHYL ACETATE Methyl nonyl acetaldehyde dimethyl acetate 112-12-9 METHYL NONYL KETONE Methyl nonyl ketone 39212-23-2 METHYL OCTALACTONE Methyl octalactone 19009-56-4 METHYL OCTIL ACETALDEHYDE Methyl octyl acetaldehyde 67674-46-8 METIL PAMPLEMOUSSE Methyl pamplemousse 110-43-0 METIL AMIL KETONE Methyl pentyl ketone 3558-60-9 KEONE Phenethyl methyl ether 93-92-5 METHYL PHENYL CARBINYL ACETATE Methyl phenyl carbinyl acetate 101-41-7 METHYL PHENYL ACETATE Methyl phenyl acetate 119-36-8 METHIL SALICILATE USP Methyl salicylate 188570-78-7 MONTAVERDI Montaverdi 18479-54-4 MUGUOL Muguol 541-91-3 LIGHT MUSCONA Muscona 1118-39-4 LlNALILA PSEUDO-ACETATE Mircenyl acetate 95962-14-4 NECTALACTONE DSR 95430109 Nectaril

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CAS P&G Name Chemical name 56973-85-4 GALBASCONA Neobutenone 111-79-5 METHYL-2-NONENATE Neofoliona 106-25-2 NEROL Nerol 7212-44-4 NEROLIDOL Nerolidol 93-04-9 METHYL BETA NAFTOL Ether Nerolina 23911-56-0 NEROLIONA 600321 Neroliona 141-12-8 NERILA ACETATE Neryl acetate 66-25-1 HEXYLALDEHYDE n-hexanal 6259-76-3 HEXYL SALICYLATE N-hexyl salicylate 124-19-6 NONYLALDEHYDE Nonaldehyde 143-08-8 NONYL ALCOHOL Nonyl alcohol 128-51-8 NOPILE ACETATE Nopyl acetate 5986-38-9 OCIMENOL Ocimenol 30168-23-1 DUPICAL Octahydro-4,7-methane indanyl denebutanal 86803-90-9 SCENTENAL Octahydro-5-methoxy-4,7-methane- 1 H-indene-2-carboxy aldehyde 4430-31-3 BI-CYCLE NONALACTONE Octaidro coumarina 103614-86-4 OCTALINOL (CONF.-FIRM) Octalinol 131812-67-4 OKOUMAL Okoumal 88-41-5 2-T-BUTYL ACETATE ClCLO-H EXILA o-tert-butylcyclohexyl acetate 1725-01-5 OXALIDE T Oxalide 28940-11-6 CALONA 1951 Oxalone 59323-76-1 OXAN Oxane 22629-49-8 2-TRI-DECENO-NITRILO Ozonil 123-11-5 ANISIC ALDEHYDE p-anisaldehyde 5471-51-2 BUTANONE FENILE HYDROXY parahydroxy phenyl butanone 142653-61-0 PARMANILA 3/055119 Parmanila 98-52-2 PATCHON Patchone 5986-55-0 HEALINGWOOD Patchouli alcohol 106-44-5 PARA-CRESOL p-Cresol

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CAS P&G Name Chemical name 103-93-5 PARACRESILA ISOBUTYRATE Cresyl p-lsobutyrate 104-93-8 PARACRESYL METHYL ETHER p-cresyl methyl ether 99-87-6 PARA-CIMENO p-Cimeno 67663-01-8 PEACHOLIDE 600038 Peacholide 39255-32-8 2METHYL ETHYL PENTANOATE Pentanoic acid, 2-methyl-, ethyl ester 10461-98-0 PEONILE Peonile 313973-37-4 PHARAONE 10 Pharaone 80858-47-5 FENAFLOR Fenaflor 60-12-8 PHENYLETYL ALCOHOL Phenylethyl alcohol 104-62-1 PHENYL ETHYL FORMIATE Phenethyl formate 56011-02-0 ISOAMYL ETH OF FENY ETHYL (AKA ANTHER) Phenethyl isoamyl ether 103-48-0 PHENYLETHYL ISOBUTYRATE Phenethyl isobutyrate 102-20-5 FENIL ETIL FENIL ACETATO Phenyl phenethyl acetate 55066-48-3 PHENOXANOL Phenoxanol 23495-12-7 ETHYL PROPIONATE PHENOXY Phenoxy ethyl propionate 122-78-1 ACETALDEHYDE PHENY Phenylacetaldehyde 101-48-4 ACETALDEHYDE PHENYL ACETAL DIMETHYL Phenyl acetaldehyde dimethyl acetal 5331-14-6 CRESSANTHER phenyl ethyl n-butyl ether 55418-52-5 RECRISTALIZED DULCINILE Piperonyl acetone 67662-96-8 PIVAROSE Pivarose Q 41724-19-0 PLICATONE Plicatone 107898-54-4 NIRVANOL 974650 Polysantol 358331-95-0 POMAROSIS Pomarose 104-45-0 DI-HIDRO ANETOL, FCC- p-Anisol propyl 52474-60-9 PRECYCLEMONE B Preciclemona B 1191-16-8 PRENYL ACETATE Prenyl acetate 68555-58-8 PRENIL SALICILATO Prenyl salicylate

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CAS P&G Name Chemical name 98-54-4 PARATERCIARY BUTY p-ter-Butylphenol 101-94-0 CRESILA FENIL ACETATE p-Tolyl phenyl acetate 80-56-8 ALFA PINENO Racemic alpha-pinene 141-25-3 RODINOL 70 Rhodinol 82461-14-1 RHUBAFURAN Rhubafuran 236391-76-7 ROMANDOLIDE 979031 Romanolide 81752-87-6 ROMASCONE Romascone 25225-10-9 ROSAMUSK Rosamusk 16409-43-1 Methyl ISOBUTENIL TETRAHYDROPYRANE Rose oxide 215231-33-7 ROSSITOL Rossitol 65113-99-7 SANDALORE Sandalore 224031-70-3 SPIROGALBANONE 10 Spirogalbanone 22457-23-4 STEMONA Stemona 13215-88-8 TABANON COEUR 659672 Tabanona 8000-41-7 ALPHA TERPINOL Terpinol 586-62-9 TERPINOLENE Terpinolene 5988-91-0 DI-HYDROCITRONELAL Geranial tetrahydro 13074-63-0 JASMYLONE Jasmine tetrahydro 78-69-3 LINACSOL Tetrahydro linalool 20780-48-7 LINETALLY TETRAHYDRO ACETATE Tetrahydro linalyl acetate 18479-57-7 MUGUOL TETRA-HYDRO Tetrahydro-mircenol 89-83-8 TIMOL NF Thymol 3913-81-3 2 DECEN-1-AL trans-2-Decennial 928-95-0 TRANS-2-HEXENOL trans-2-Hexenol 65405-70-1 DECENAL (TRANS-4) trans-4-Decen-1 -al 4180-23-8 ANETOL USP trans-Anethole 106-24-1 ALGUE NE trans-Geraniol 90-17-5 TRENCHLOMETHYL ACETATE FENIL CARBINILA Trichloromethyl phenyl carbinyl acetate 2500-83-6 FLOWER ACETATE Tri-cycle decenyl acetate / Flower acetate

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CAS P&G Name Chemical name 77-93-0 GALBANOLENO SUPER 10% IN TEC Triethyl citrate 16251-77-7 TRIFERNAL 989-007 Rifernal T 112-44-7 UNDECIL ALDEHYDE Undecanal 81782-77-6 UNDECAVERTOL Undecavertol 121-33-5 VANILLIN Vanillin 20665-85-4 ISO BUTAVAN Vanillin isobutyrate 94-86-0 VANITROPO Vanitropo 5533-03-9 VANIWHITE Vaniwhite 65443-14-3 VELOUTONE Veloutone 4707-47-5 LRG 201 Veramoss 120-14-9 CORPS 4322 Veratraldehyde 27135-90-6 VERDALIA A Verdalia A 13491-79-7 VERDOL Verdol 41519-23-7 VERDURAL B EXTRA Verdural B Extra 32388-55-9 ACETYL CEDRENO Vertofix 68738-99-8 AGRUMEA Vertosine 68083-58-9 VETIKOL ACETATE 3/080515 Vetikol acetate 87731-18-8 VIOLIFF Violiff 133636-82-5 WOLFWOOD 992393 Wolfwood 154171-76-3 YSAMBER K 3/055120 Ysamber 105-68-0 AMILA PROPIONATE 93-99-2 FENIL BENZOATE 94-47-3 PHENYL ETHYL BENZOATE

In one aspect, the taste and aroma may comprise a flavor and aroma used in oral treatment compositions, and may comprise menthol (L, D, racemic), anethole and anise oil, eucalyptol and eucalyptus oil, peppermint oils, Japanese mint oils or mint arvensis, common mint oils, l-carvone, clove oils, cinnamic aldehyde and cinnamon derivatives, cooling agents (also called sensory elements, such as those described in US patent no. ° 2007/0233026 A1) as aliphatic carboxamides (including WS-3, available as ISE 3000 from Qaroma, Inc., and WS-23, available as ISE 1000 from Qaroma, 10 Inc.), ketal (including MGA (available with Symrise)), derived from

38/57 hexyl (including TK10, Coolact, available from LIPO Chemicals of Paterson, NJ, USA), and succinated monomenthyl (available under the brand name Physcool), sweeteners such as sodium saccharin, sucralose, neohesperidine, eugenol and clove oils Indian guinea, cinnamic aldehyde and cinnamon derivatives, flavored flavoring materials, methyl salicylate and oil-derived products, and combinations thereof.

In one aspect, the flavoring may comprise a flavor and aroma 'modifier', and may include a fruity or dairy flavoring such as vanillin, ethyl vanillin, sulfur derivatives with milk tones and / or exotic fruits, furanone, ethyl esters, apricots , ionones, allyl esters, butyric esters, essential oils from flowers, leaves and wood, absolutes, plant extracts, and combinations thereof.

The raw materials for perfume, accords and flavorings can be obtained from one or more of the following companies: Firmenich (Geneva, Switzerland), Givaudan (Argenteuil, France), IFF (Hazlet, NJ, USA), Quest (Mount Olive, NJ, USA), Bedoukian (Danbury, CT, USA), Sigma Aldrich (St. Louis, MO, USA), Millennium Specialty Chemicals (Olympia Fields, IL, USA), Polarone International (Jersey City, NJ, USA), Fragrance Resources (Keyport, NJ, USA) and Aroma & Flavor Specialties (Danbury, CT, USA). Process for Production of Encapsulated Benefit Agents

The encapsulated benefit agents employed for the present invention can be produced using the teachings of U.S. Patent No. 6,592,990 B2 and / or 6,544,926 B1 and the examples presented herein.

Anionic emulsifiers are typically used during the encapsulation process to emulsify the beneficial agent prior to microcapsule formation. Without sticking to the theory, it is believed that anionic materials interact adversely with cationic surfactant assets that are often found in compositions as tissue treatment compositions - this can produce an aesthetically unpleasant aggregation of particles that are employed in said composition. In addition to unacceptable aesthetics, such aggregates can lead to rapid phase separation of particles from the main phase. The applicants found

39/57 that such aggregates can be prevented by the addition of certain aggregate inhibiting materials including materials selected from the group consisting of salts, polymers and mixtures thereof. Useful aggregate inhibiting materials include divalent salts such as magnesium salts, for example, magnesium chloride, magnesium acetate, magnesium phosphate, magnesium formate, magnesium boride, magnesium titanate, magnesium sulfate heptahydrate; calcium salts, for example, calcium chloride, calcium formate, calcium acetate, calcium bromide; trivalent salts, such as aluminum salts, for example, aluminum sulfate, aluminum phosphate, aluminum chloride nhydrate and polymers that have the ability to suspend anionic particles such as polymers for suspending dirt, for example, polyethylene imines, alkoxylated polyethylene imines , polyquaternium-6 and polyquaternium-7.

In one aspect of the invention, encapsulated beneficial agents are manufactured and are subsequently coated with a material to reduce the leakage rate of the particulate beneficial agent when the particles are subjected to an environment whose volume contains, for example, surfactants, polyesters, and solvents. Some non-limiting examples of coating materials that can serve as barrier materials include materials selected from the group consisting of polyvinyl pyrrolidone homopolymer, and their various copolymers with styrene, vinyl acetate, imidazole, monomers containing primary and secondary amines, methyl, polyvinyl acetate, maleic anhydride; homopolymer of polyvinyl alcohol, and its various copolymers with vinyl acetate, 2-acrylamide-2-methyl propane sulfonate, primary and secondary amine containing monomers, imidazoles, methyl acrylate; polyacrylamides; polyacrylic acids; microcrystalline waxes; paraffin waxes; modified polysaccharides such as waxy corn or toothed corn starch, succinated octenyl starches, derived starches such as hydroxyethylated or hydroxypropylated starches, carrageenan, guar gum, pectin, xanthan gum; modified celluloses such as hydrolyzed cellulose acetate, hydroxy propyl cellulose, methyl cellulose, and the like; modified proteins like gelatin; hydrogenated and non-hydrogenated polyalkenes; fatty acids; hardened layers like crosslinked urea

40/57 with formaldehyde, gelatin-polyphosphate, melamine-formaldehyde, cross-linked polyvinyl alcohol with sodium tetraborate or gluteraldehyde; styrene-butadiene latex, ethyl cellulose, inorganic materials such as clays, including magnesium silicates, aluminosilicates; sodium silicates and the like, and mixtures thereof. These materials can be obtained from CP Kelco Corp. San Diego, California, USA; Degussa AG of Dusseldorf, Germany; BASF AG of Ludwigshafen, Germany; Rhodia Corp. Cranbury, New Jersey, USA; Baker Hughes Corp. Houston, Texas, USA; Hercules Corp. Wilmington, Delaware, USA; Agrium Inc. of Calgary, Alberta, Canada, ISP of New Jersey, USA.

Equipment suitable for use in the processes presented here may include reactors with continuous agitation tanks, homogenizers, turbine agitators, recirculating pumps, paddle mixers, plow mixers, ribbon mixers, vertical axis granulators and drum mixers. in both batch and, where available, continuous process configurations, spray dryers and extruders. Such equipment can be obtained from Lodige GmbH (Paderborn, Germany), Littleford Day, Inc. (Florence, Kentucky, USA), Forberg AS (Larvik, Norway), Glatt Ingenieurtechnik GmbH (Weimar, Germany), Niro (Soeborg, Denmark) ), Hosokawa Bepex Corp. (Minneapolis, Minnesota, USA), Arde Barinco (New Jersey, USA).

Formaldehyde hijacking

In one aspect, an encapsulated benefit agent can be combined with a formaldehyde scavenger. In one aspect, an encapsulated benefit agent may comprise the encapsulated benefit agent of the present invention. Suitable formaldehyde scavengers include materials selected from the group consisting of sodium bisulfite, urea, ethylene urea, cysteine, cysteamine, lysine, glycine, serine, carnosine, histidine, glutathione, 3,4-diaminobenzoic acid, allantoin, glycouryl, acid anthranilic, methyl anthranylate, methyl 4-amino benzoate, ethyl acetoacetate, acetoacetamide, malonamide, ascorbic acid, 1,3-dihydroacetone dimer, biuret, oxamide, benzoguanamine, pyroglutamic acid, pyro

41/57 gallol, methyl gallate, ethyl gallate, propyl gallate, triethanol amine, succinamide, thiabendazole, benzotriazole, triazole, indoline, sulfanilic acid, oxamide, sorbitol, glucose, cellulose, poly (vinyl) alcohol, poly (vinylformamide) ) partially hydrolyzed, poly (vinyl amine), poly (ethylene imine), poly (oxyalkylene amine), poly (vinyl) -co-poly (vinyl amine), poly (4aminostyrene), poly (l-lysine), chitosan, hexane diol, ethylenediamine-N, N'bisacetoacetamide, N- (2-ethylhexyl) acetoacetamide, 2-benzoylacetoacetamide, N- (3-phenylpropyl) acetoacetamide, lilial, helional, melonal, triple, 5,5-dimethyl-

1.3- cyclohexanedione, 2,4-dimethyl-3-cyclohexenecarboxaldehyde, 2,2-dimethyl-

1.3- dioxane-4,6-dione, 2-pentanone, dibutyl amine, triethylenetetramine, ammonium hydroxide, benzylamine, hydroxycitronelol, cyclohexanone, 2-butanone, dione pentane, dehydroacetic acid or a mixture thereof. These formaldehyde scavengers can be obtained from Sigma / Aldrich / Fluka of St. Louis, MO, USA, or PolySciences, Inc. of Warrington, PA, USA.

Such formaldehyde scavengers are typically combined with an aqueous slurry containing said release particle containing beneficial agent, in a content, based on the total weight of the slurry, from about 2% to about 18%, from about 3.5% to about 14% or even from about 5% to about 13%.

In one aspect, such formaldehyde scavengers can be combined with a product containing a release particle containing beneficial agent, said scavengers being combined with said product in a content, based on the total weight of the product, of about 0.005% to about 0.8%, alternatively from about 0.03% to about 0.5%, alternatively from about 0.065% to about 0.25% of the product formulation.

In another aspect, such formaldehyde scavengers can be combined with an aqueous paste containing said encapsulated benefit agent, on a level, based on the total weight of the aqueous paste, from about 2% by weight to about 14 % by weight from about 3.5% by weight to about 14% by weight, or even from about 5% by weight to about 14% by weight, and said paste aqueous solution can be added to a matrix

42/57 product to which an identical or different sequester can be added at a level, based on the total weight of the product, from about 0.005% to about 0.5%, alternatively from about 0.01% to about 0.25%, alternatively about 0.05% to about 0.15% of the product formulation,

In one aspect, one or more of the formaldehyde scavengers mentioned above can be combined with a consumer product that contains a level-encapsulated benefit agent, based on the total weight of the cloth to accent liquid cloth, from 0.005% to about from 0.8%, alternatively about 0.03% to about 0.4%, alternatively about 0.06% to about 0.25% of the product formulation.

In one aspect, such formaldehyde scavengers can be combined with a liquid laundry detergent product that contains a release particle containing beneficial agent, said scavengers being selected from the group consisting of sodium bisulfite, urea, ethylene urea. , cysteine, cysteamine, lysine, glycine, serine, carnosine, histidine, glutathione, 3,4-diaminobenzoic acid, allantoin, glucouril, anthranilic acid, methyl anthranylate, methyl 4-amino benzoate, ethyl acetoacetate, acetoacetamide, malonamide, ascorbic acid , 1,3-dihydroxy dimer acetone, biuret, oxamide, benzoguanamine, pyroglutamic acid, pyrogallol, methyl gait, ethyl gait, propyl gait, triethanol amine, succinamide, thiabendazole, benzotriazole, triazole, indoline, sulfanilic acid, oxamide sorbitol, glucose, cellulose, poly (vinyl alcohol), poly (partially hydrolyzed vinylformamide, poly (vinyl amine), poly (ethylene imine), poly (oxyalkyl) noamine), poly (vinyl) -co-poly (vinyl amine), poly (4-aminostyrene), poly (l-lysine), chitosan, hexane diol, ethylenediamine-N, N'-bisacetoacetamide, N- (2-ethylhexyl) acetoacetamide, 2-benzoylacetoacetamide, N- (3phenylpropyl) acetoacetamide, lilial, helional, melonal, triple, 5,5-dimethyl-1,3cyclohexanedione, 2,4-dimethyl-3-cyclohexenecarboxaldehyde, 2,2-dimethyl -1,3dioxane-4,6-dione, 2-pentanone, dibutyl amine, triethylenetetramine, ammonium hydroxide, benzylamine, hydroxycitronelol, cyclohexanone, 2-butanone, dione pentane, dehydroacetic acid and mixtures thereof, and combined with the

43/57 said liquid laundry detergent product in a content, based on the total weight of the liquid laundry detergent product, from about 0.003% by weight to about 0.20% by weight, or from about 0.03% by weight to about 0.20% by weight or from about 0.06% by weight to about 0.14% by weight.

In one aspect, such formaldehyde scavengers can be combined with a hair conditioning product that contains a release particle containing benefit agent, in a content, based on the total weight of the hair conditioning product, of about 0.003%, in about 0.30% by weight, about 0.03% by weight, about 0.20% by weight, or about 0.06% by weight, about 0.14% by weight, the said selection of abductors being identical to the list of abductors mentioned in the previous paragraph mentioned for a liquid detergent product for washing clothes.

Compositions comprising release particles containing beneficial agent

The products intended for the consumers of the reguerentes may comprise a modality of the composition for release of benefit agent presented in the present application. In one aspect, said products intended for the consumer can be a powder, granule or essentially dry detergent.

In one aspect, a consumer product that may comprise one or more of the compositions for releasing beneficial agents of the present invention and an auxiliary compound ingredient is presented.

In one aspect of the consumer product presented above, said auxiliary compound of the consumer product can be selected from the group consisting of polyesters, for example, cationic polyesters, surfactants, builders, chelating agents, transfer inhibitors. dyes, dispersants, enzymes, and enzyme stabilizers, catalytic materials, bleach activators, polymeric dispersing agents, removal / anti-reposition agents

44/57 clay dirt, bleaches, foam suppressants, dyes, perfume and additional perfume release systems, structural elastifying agents, fabric softener, vehicles, hydrotropes, elements and / or pigments that are auxiliary to processing and mixtures thereof.

In one aspect of the aforementioned consumer product, said consumer product may comprise a total of, based on the total weight of the product intended for the consumer, from about 0.1% to about 20%, from about 0 , 2% to about 15%, from about 0.3% to about 10%, from about 0.4% to about 8%, or even from about 0.5% to about 5% one or more of the beneficial agent release compositions of the present invention.

In one aspect of the aforementioned consumer product, said consumer product may comprise one or more of the benefit agent release compositions of the present invention and a material selected from the group consisting of dyes, perfume, optical bleaches, auxiliary elements of deposition, and mixtures thereof.

Compositions for releasing beneficial agents can be used in laundry detergent compositions (eg TIDE®), hard surface cleaners (eg MR CLEAN®), dishwashing liquids in an automatic washer (eg , CASCADE®), and floor cleaners (for example, SWIFFER®). Some non-limiting examples of cleaning compositions may include those described in US Patent Nos. 4,515,705, 4,537,706, 4,537,707, 4,550,862, 4,561,998, 4,597,898, 4,968,451, 5,565,145, 5,929,022, 6,294,514, and 6,376,445. The cleaning compositions presented in the present invention are typically formulated so that during use in aqueous cleaning operations, the washing water has a pH between about 6.5 and about 12 or between about 7.5 and 10, 5. Liquid dishwash product formulations typically have a pH between about 6.8 and about 9.0. Cleaning products are typically formulated to have a pH of about 7 to about 12. Techniques for controlling pH at levels of recommended use

Recommended 45/57 include the use of buffers, alkalis, acids, etc., and are well known to those skilled in the art.

Auxiliary materials

Although not essential to the purposes of the present invention, the non-limiting list of auxiliary compounds illustrated hereinafter in this document is suitable for use in instant compositions and can be desirably incorporated in certain aspects, for example to aid or improve performance , to treat the substrate to be cleaned, or to modify the aesthetics of the composition as is the case with perfumes, dyes, paints or the like. Auxiliary compounds are understood to be in addition to the components that are supplied through the applicants' agglomerate / particle. The exact nature of these additional components, as well as their levels of incorporation, will depend on the physical form of the composition and the nature of the cleaning operation in which it will be used. Suitable auxiliary materials include, but are not limited to, polymers, for example, cationic polymers, surfactants, builders, chelating agents, dye transfer inhibiting agents, dispersants, enzymes, and enzyme stabilizers, catalytic materials, bleach activators, agents dispersing polymers, dirt and clay / anti-redeposition agents, bleaches, foam suppressants, dyes, perfume and additional perfume delivery systems, structural elasticizing agents, fabric softeners, vehicles, hydrotropes, processing auxiliary elements and / or pigments. In addition to the description below, suitable examples of such other auxiliary compounds and contents of use are found in U.S. Patent Nos. 5,576,282, 6,306,812 B1 and 6,326,348 B1.

As reported, auxiliary ingredients are not essential to the Applicants' tissue cleaning and treatment compositions. Accordingly, certain modalities of the Applicants' compositions do not contain one or more of the following auxiliary composite materials: discoloration activators, surfactants, builders, chelating agents, dye transfer inhibiting agents, dispersants, enzymes and stabilizers

46/57 of enzymes, catalytic metal complexes, polymeric dispersing agents, clay and dirt removal / anti-reposition agents, bleaching agents, foam suppressants, dyes, additional perfumes and perfume release systems, structural elastifying agents, fabric softeners, vehicles, hydrotropes, processing auxiliary elements and / or pigments. However, when one or more auxiliary compounds are present, they can be present as detailed below:

Surfactants - The compositions according to the present invention may comprise a surfactant or a surfactant system in which the surfactant can be selected from nonionic surfactants, anionic surfactants, cationic surfactants, ampholytic surfactants, zwitterionic surfactants, semipolar nonionic surfactants. The surfactant is typically present in levels of about 0.1%, about 1%, or even about 5%, by weight, of the cleaning compositions, and up to about 99.9%, up to about 80%, or even up to about 35%, and up to about 30%, by weight, of the cleaning compositions.

Builders - The compositions of the present invention can comprise one or more detergent builders or builder systems. When present, the compositions will typically comprise at least about 1% builder, or from about 5% or 10% to about 80%, 50%, or even 30%, by weight, of said builder. Builders include, but are not limited to, alkali metal, ammonium and ammonium alkali polyphosphate salts, alkali metal silicates, alkaline earth metal and alkali metal carbonates, polycarboxylate compounds from aluminum silicate builders, polycarboxylate hydroxy ether, anhydride copolymers maleic with ethylene or methyl vinyl ether, 1,3,5-trihydroxy benzene-2,4,6-trisulfonic acid and carboxy methyl-succinic oxide, the various salts of alkali metal, ammonium and ammonium polyacetic acids substituted as ethylenediamine tetraacetic acid and nitrile triacetic acid, as well as polycarboxylates such as melitic acid, succinic acid, oxisuccinic acid, polymaleal acid, benzene 1,3,5-tricarboxylic acid, carboxy methyl oxide succinic acid and soluble salts thereof.

Chelating agents - The compositions of the present invention can

47/57 may also optionally contain one or more chelating agents of copper, iron and / or manganese. If used, chelating agents will generally comprise from about 0.1% by weight of the composition of the present invention to about 15%, or even from about 3.0% to about 15% by weight of the compositions of the present invention.

Pigment transfer inhibiting agents - The compositions of the present invention may also contain one or more pigment transfer inhibiting agents. Suitable dye transfer inhibiting polymeric agents include, but are not limited to, polyvinyl pyrrolidone polymers, polyamine N-oxide polymers, N-vinyl pyrrolidone and N-vinyl imidazole copolymers, polyvinyl oxazolidones and polyvinyl imidazoles, or mixtures thereof. . When present in the compositions of the present invention, dye transfer inhibiting agents are in the range of about 0.0001%, about 0.01%, about 0.05% by weight of the composition for cleaning at about 10%, about 2%, or even about 1% by weight of the cleaning composition.

Dispersants - The compositions of the present invention can also contain dispersants. Suitable water-soluble organic materials are homo or copolymeric acids, or their salts, in which the polycarboxylic acid contains at least two carboxyl radicals separated from each other by no more than two carbon atoms.

Enzymes - Cleaning compositions can comprise one or more enzymes, which provide benefits of cleaning and / or tissue treatment performance. Examples of suitable enzymes include, but are not limited to, hemicellulases, cellulases, cellobiose dehydrogenases, peroxidases, proteases, xylanases, lipases, phospholipases, esterases, cutinases, pectinases, mannases, pectate liases, keratinases, reductases, oxidases, lipoxidases, phenoxyoxidases, ligninases, pululanases, tanases, pentosanases, malanases, β-glucanases, arabinosidases, hyaluronidase, chondroitinase, laccase, and amylases, or mixtures thereof. A typical combination is a cocktail of enzymes that can comprise, for example, a protease and a lipase together with amylase. When present in

48/57 a cleaning composition, the additional enzymes mentioned above can be present in levels ranging from about 0.00001% to about 2%, from about 0.0001% to about 1% or from about 0.001 % to about 0.5% of enzyme protein, by weight of the composition.

Suitable enzymes are commercially available from Genencor International Inc., Paio Alto, California, AB Enzymes GmbH, Darmstadt, Germany and Novozymes A / S, Bagsvaerd, Denmark, and include Alcalase®, Savinase®, Primase®, Durazym®, Polarzyme ®, Kannase®, Liquanase®, Ovozyme®, Neutrase®, Everlase®, Esperase®, Maxatase®, Maxacal®, Maxapem®, Properase®, Purafect®, Purafect Prime®, Purafect Ox®, FN3®, FN4®, Excellase ® and Purafect OXP®, DURAMYL®, LIQUEZYME® TERMAMYL®, TERMAMYL ULTRA®, NATALASE®, SUPRAMYL®, STAINZYME®, STAINZYME PLUS®, STAINZYME ULTRA®, FUNGAMYL®, BAN® Lipolase®, Lipprase Ultra®, Lipoprase Ultra® Lipex®, Mannaway®, Pectaway®, Pectawash®, Purabrite®, Celluclean®, Carezyme®, Celluzyme®, Biotouch®, Endolase® and Puradax HA®.

Enzyme Stabilizers - Enzymes for use in compositions, for example, detergents can be stabilized by various techniques. The enzymes used in this case can be stabilized by the presence of soluble water sources of calcium and / or magnesium ions in the final compositions that supply these ions to the enzymes.

Catalytic metal complexes - Applicants' compositions may include catalytic metal complexes. One type of bleach catalyst containing metal is a catalyst system that contains a transition metal cation with catalytic activity defined for bleach, such as copper, iron, titanium, ruthenium, tungsten, molybdenum or manganese cations, an auxiliary metal cation with little or no catalytic activity for bleach, such as zinc or aluminum cations, and a hijacker that has defined stability constants for catalytic and auxiliary metal cations, particularly ethylenediamine tetraacetic acid, ethylene diamine tetra (methylene phosphonic acid), and soluble salts these substances in water. Such catalysts are disclosed in U.S. Patent No. 4,430,243.

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If desired, the compositions of the present invention can be catalyzed by means of a manganese compound. Such compounds and usage levels are well known in the art and include, for example, the manganese-based catalysts disclosed in U.S. Patent No. 5,576,282.

The cobalt-based bleaching catalysts useful in the present invention are known, and are described, for example, in U.S. Patent Nos. 5,597,936 and 5,595,967. Such cobalt-based bleaching catalysts are readily prepared by known procedures, as disclosed in U.S. Patent Nos. 5,597,936 and 5,595,967.

The compositions of the present invention may also suitably include a transition metal complex of a rigid macropolicy linker - abbreviated as MRL. As a matter of practice, but without limiting it, the cleaning compositions and processes of the present invention can be adjusted to offer something in the order of at least one part per hundred million of the beneficial agent's MRL species in the medium of aqueous wash and can offer about 0.005 ppm to about 25 ppm, about 0.05 ppm to about 10 ppm and, or even about 0.1 ppm to about 5 ppm, the MRL in the wash liquid .

Preferred transition metals in the present transition metal based bleach catalyst include manganese, iron and chromium. Preferred MRLs for use in the present invention are a special type of cross-linked ultra-rigid binder, such as 5,12-diethyl-1,5,8,12-tetraazabicyclo [6.6.2] hexadecane.

Suitable transition metal MRLs are readily prepared by known procedures, as taught, for example, in WO 00/32601, and in U.S. Patent No. 6,225,464.

Manufacturing process using compositions

The compositions of the present invention can be formulated in any suitable form and prepared by any process chosen by the formulator, some non-limiting examples of which are

50/57 described in U.S. Patent Nos. 5,879,584, 5,691,297, 5,574,005, 5,569,645, 5,565,422, 5,516,448, 5,489,392, 5,486,303.

Method of Use

Compositions containing the encapsulated benefit agent shown in the present invention can be used to clean and treat a situs, among others, a surface or cloth. Typically at least a portion of the situs is brought into contact with one embodiment of the Applicants' composition, in pure form or diluted in a liquid, for example, a washing liquid, and then the situs can be optionally washed and / or rinsed. In one aspect, a situs can be optionally washed and / or rinsed, brought into contact with one or more of the agent-releasing compositions of the present invention or a consumer product comprising one or more of the agent-releasing compositions of benefit of the present invention and then optionally washed and / or rinsed. For the purposes of the present invention, washing includes, but is not limited to, rubbing and mechanical agitation. The fabric can be the majority of fabrics capable of treating laundry or treating under normal consumer use. Liquids that can comprise the compositions shown can have a pH of about 3 to about 11.5. These compositions are typically used in concentrations of about 500 ppm to about 15,000 ppm, in solution. When the washing solvent is water, the water temperature is typically in the range of about 5 ° C to about 90 ° C and, when the situs comprises a fabric, the mass ratio between water and fabric is typically in the range of about 1: 1 to about 30: 1. Testing methods

It is understood that the test methods that are presented in the test method section of the present application should be used to determine the respective values of the Applicants' invention parameters as described and claimed in the present invention.

Method for Determining the Characteristic Dimension (Agglomerates and Particulates)

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The particle size distribution of the beneficial agent release composition is determined using the ASTM E726-01 test method, Particle Size Distribution of Granular Carriers and Granular Pesticides. Specifically, the method must be performed using a Tyler RoTap sieve shaker equipped with a cast iron sieve stack lid with a centrally mounted cork (W.S. Tyler Company, Cleveland, Ohio, USA). At least 5 screen sizes must be selected to cover the full particle size range of the material being analyzed (step 7.1). If after sieving, more than 40% by weight of the sample is not found in a single sieve, then the sieve selection should be modified and the sample should be tested again until <40% by weight is found in all sieves.

The following parameters for operating RoTap should be applied to step 7.4 of the method:

1) 152 beats / minute

2) 285 rpm elliptical movement

3) Cork on the lid to push 5 mm from the top of the handling mug.

4) A hammer drop of 33 mm from the height of the hammer peak to the top of the cork.

5) Sieve time 5 minutes.

The data are plotted in a semi log plot with the micron size opening of each sieve plotted against the logarithmic abscissa and the percentage of cumulative mass (Q3) plotted against the linear ordinate. An example of the data representation above is given in ISO 92761: 1998, Representation of results of particle size analysis - Part 1: Graphical Representation, figure A.4. The average particle size of the initial particle material (D50), according to the purposes of this invention, is defined as the abscissa value at the point where the cumulative mass percentage is equal to 50 percent, and is calculated by a straight interpolation between the data points directly above (a50) and below (b50) 50% of the value using the equation below:

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D50 = 10 ^A [Log (Da50) - (Log (Da50) - Log (Db50)) * (Qa50 - 50%) / (Qa50 Qb50)] where Qa50 and Qb50 are the cumulative mass percentage values of the data immediately above and below the 50th percentile, respectively, and Da50 and Db50 are the values, in microns, of the screen sizes corresponding to these data. The average particle size on a mass basis is considered, for purposes of the present application, to be the characteristic dimension.

Method for Determining the Characteristic Dimension (Extruded Products)

The diameter of an extrudate is obtained by measuring with the use of a micrometer while the material is at a temperature of 20 ° C. In order to determine the average, five representative extrudates are removed from the sample to be tested and are measured, taking care to deform the extrudates during the measurement process and the arithmetic mean of such measurements is then calculated. Such arithmetic mean is considered, for the purposes of this application, to be the characteristic dimension of the extruded products. Examples

Although particular embodiments of the present invention have been illustrated and described, it should be apparent to those skilled in the art that various other changes and modifications can be made without departing from the character and scope of the invention. Therefore, it is intended to cover in the appended claims all such changes and modifications that fall within the scope of the present invention.

Example 1 Melamine-based polyurea capsule (80% core / 20%, by weight, wall)

A first mixture is prepared by combining 208 grams of water and 5 grams of acrylic acid copolymer - alkyl acrylate (Polysciences, Inc. of Warrington, Pennsylvania, USA). The pH of this first mixture is adjusted to 5.0 using acetic acid. 125 grams of the core material of the capsule comprising a fragrance oil are added to the first mixture at a temperature of 45 ° C to form an emulsion. The capsule wall is formed as follows: 9

53/57 grams of a copolymer prepolymer of corresponding capsule wall material (butyl acrylate-acrylic acid copolymer) and 90 grams of water and the pH adjusted to 5.0. 28 grams of a partially methylated methylol melanin resin solution (Cymel 385, 80% solids, Cytec) are added to this mixture. This mixture is added to the fragrance oil in water emulsion described above with stirring at a temperature of 45 ° C. High speed mixing is used to achieve an average volumetric particle size of 15 microns. The temperature of the mixture is gradually raised to 65 ° C, and is maintained at that temperature overnight with continuous stirring to initiate and complete encapsulation. To form the wall of the acrylic acid acrylate copolymer capsule, the alkyl group can be selected from ethyl, propyl, butyl, amyl, hexyl, cyclohexyl, 2-ethyl hexyl or other alkyl groups having one to about sixteen carbons, preferably one to eight carbons.

Example 2 Melamine-based polyurea capsule containing a chelator (80% core / 20%, by weight, wall)

A first mixture is prepared by combining 208 grams of water and 5 grams of acrylic acid copolymer - alkyl acrylate (Polysciences, Inc. of Warrington, Pennsylvania, USA). The pH of this first mixture is adjusted to 5.0 using acetic acid. In a separate vial, 5 mg of ethylenediamine tetraacetic acid (EDTA) is added to a mixture of 125 grams of the core material of the capsule that comprises a fragrance oil and mixed for 20 minutes. The second mixture is added to the first mixture at a temperature of 45 ° C to form an emulsion. The ingredients to form the capsule wall material are prepared as follows: 9 grams of a copolymer prepolymer of corresponding capsule wall material (butyl acrylate-acrylic acid copolymer) and 90 grams of water are combined. pH is adjusted to 5.0. To this mixture are added 28 grams of a solution of partially methylated methylol melanin resin (Cymel 385, 80% solids, available from Cytec). This mixture is added to the fragrance oil in water emulsion described above with stirring at a

54/57 temperature of 45 ° C. High speed mixing is used to achieve an average volumetric particle size of 15 microns. The temperature of the mixture is gradually raised to 65 ° C, and is maintained at that temperature overnight with continuous stirring to initiate and complete encapsulation. To form the wall of the acrylic acid-acrylic acrylate copolymer capsule, the alkyl group can be selected from ethyl, propyl, butyl, amyl, hexyl, cyclohexyl, 2-ethyl hexyl or other alkyl groups having one to about sixteen carbons, preferably one to eight carbons.

Example 3

A 9 kg aliquot of perfume microcapsule slurry of example 1 is mixed using a Eurostar mixer (IKA) with an R1382 connection and a constant 200 RPM rotation. To the aliquot, 5.4 g of ethylenediamine disuccinic acid (EDDS) are added, followed by 500 g of methyl cellulose carboxy (CP Kelco) under mixing using the Eurostar mixer with the same connection and rotation as described above. The slurry is mixed for a total of two hours or until a uniform slurry is formed.

Example 4

A 9 kg aliquot of perfume microcapsule slurry from example 2 is mixed with a Eurostar mixer (IKA) with an R1382 connection at a constant rotation of 200 RPM. 500 g of methyl cellulose carboxy (CP Kelco) are added to the aliquot under mixing using the Eurostar mixer with the same connection and rotation as described above. The slurry is mixed for a total of two hours or until a uniform slurry is formed.

Example 5

1.28 kg of precipitated silica Sipernat® 22S (Degussa) are added in an F-20 paddle mixer (Forberg). The mixer is initially activated for 5 seconds to distribute the silica evenly at the base of the mixer. The mixer is switched off and 8.25 kg of paste, prepared according to example 2, are distributed evenly over the powder. The mixer is then operated at 120 rpm for a total of 30 seconds.

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After mixing, the wet particles are removed from the mixer and sieved using a 2000 micron sieve to remove the oversized. The product passing through the screen is dried in batches of 500 g in a CDT 0.02 fluid bed dryer (Niro) to a final moisture content of 20% by weight, measured by Karl Fischer. The dryer is operated at an inlet temperature of 140 ° C and an air speed of 0.68 m / s.

Examples 6-13

Examples of laundry detergents compositions comprising the perfume composition are included below.

Feedstock % by weight of laundry detergent compositions 6 7 8 9 10 11 12 13 Linear alkyl benzene sulfonate 7.1 67 11.0 10.6 6.9 4.5 10.1 8.9 C12-15 alkyl sulfate sodium ethoxy, having an average molar degree of ethoxylation of 3 3.5 0.0 1.5 0.0 0.0 0.0 0.0 1.9 Acrylic acid / maleic acid copolymer 3.6 1.8 4.9 2.0 1.0 1.6 3.9 2.3 Sodium aluminosilicate (zeolites 4A) 4.0 0.5 0.8 1.4 16.3 0.0 17.9 2.4 Sodium tripolyphosphate 0.0 17.5 0.0 15.8 0.0 23.3 0.0 0.0 Sodium carbonate 23.2 16.8 30.2 17.3 18.4 9.0 20.8 30.0 Sodium sulphate 31.4 29.4 35.5 7.2 26.3 42.8 33.2 28.3 Sodium silicate 0.0 4.4 0.0 4.5 0.0 6.1 0.0 4.6 C1-15 alkyl ethoxylated alcohol, having an average molar degree of ethoxylation of 7 0.4 2.6 0.8 2.5 3.1 0.3 3.8 0.4 Sodium Percarbonate 16.0 0.0 8.4 20.4 13.1 3.6 0.0 7.0 Sodium perborate 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 Tetraacetylethylenediamine (TAED) 2.2 1.7 0.0 4.7 3.6 0.0 0.0 0.8 Calcium Bentonite 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.6 Citric acid 2.0 1.5 2.0 2.0 2.5 1.0 2.5 1.0

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Feedstock % by weight of laundry detergent compositions 6 7 8 9 10 11 12 13 Protease (84 mg active / g) 0.14 0.12 0.0 0.12 0.09 0.08 0.10 0.08 Amylase (22 mg active / g) 0.10 0.11 0.0 0.10 0.10 0.0 0.14 0.08 Lipase (11 mg active / g) 0.70 0.50 0.0 0.70 0.50 0.0 0.0 0.0 Cellulase (2.3 mg active / g) 0.0 0.0 0.0 0.0 0.0 0.0 0.18 0.0 Beneficial Agent Composition of Example 3 1.4 0.6 0.8 1.0 0.7 0.3 0.7 1.2 Water and miscellaneous qsp 100%

The equipment and materials described in examples 1 to 13 can be obtained from the following companies: IKA Werke GmbH & Co. KG, Staufen, Germany; CP Kelco, Atlanta, USA; Forberg International AS, Larvik, Norway; Degussa GmbH, Düsseldorf, Germany; Niro A / S, Soeberg, 5 Denmark; Baker Perkins Ltd, Peterborough, United Kingdom; Nippon Shokubai, Tokyo, Japan; BASF, Ludwigshafen, Germany; Braun, Kronberg, Germany; Industrial Chemicals Limited, Thurrock, United Kingdom; Primex ehf, Siglufjordur, Iceland; ISP World Headquarters; Polysciences, Inc. of Warrington, Pennsylvania, USA; Cytec Industries Inc., New Jersey, USA; Internati10 onal Specialty Products, Wayne, New Jersey, USA; P&G Chemicals Americas, Cincinnati, Ohio, USA; Sigma-Aldrich Corp., St. Louis, Missouri, USA.

The dimensions and values presented in the present invention should not be understood as being strictly limited to the exact numerical values mentioned. Instead, except where otherwise specified, each of these dimensions is intended to mean both the mentioned value and a range of functionally equivalent values around that value. For example, a dimension shown as 40 mm is intended to mean about 40 mm.

All documents cited in the Detailed Description of Inven57 / 57 tion are, for the most part, incorporated herein by reference, and the citation of any document should not be construed as admitting that it represents prior art with respect to the present invention. If there is a conflict between any meaning or definition of a term mentioned in this document and the meaning or definition of the same term in a document incorporated by way of reference, the meaning or definition attributed to the term mentioned in this document will take precedence.

Although particular embodiments of the present invention have been illustrated and described, it should be apparent to those skilled in the art that various other changes and modifications can be made without departing from the character and scope of the invention. Therefore, it is intended to cover in the appended claims all such changes and modifications that fall within the scope of the present invention.

Claims (4)

1. Composition for release of benefit agent, characterized by the fact that it comprises a material selected from the group consisting of: a) a particleboard, particulate and / or extruded, said particleboard, particulate and / or extruded comprises chelator and an encapsulated benefit agent that has a core and a housing encapsulating said core; b) an agglomerate, particulate and / or extruded, said agglomerate, particulate and / or extruded comprising a chelator and an encapsulated benefit agent that has a core and a housing encapsulating said core, said encapsulated benefit agent comprises chelator in its carcass and / or core; c) a particulate and / or extruded agglomerate, said particulate, and / or extruded agglomerate comprising an encapsulated benefit agent having a core and a housing encapsulating said core, said encapsulated benefit agent comprising chelating in its housing and / or core, and d) combinations thereof, wherein said encapsulated benefit agent preferably comprises a material selected from the group consisting of perfume comprising aldehyde, brighteners, insect repellents, silicones, waxes, flavorings, vitamins, fabric softening agents, agents for treatment of skin, enzymes, bactericidal agents, bleaching agents, and combinations thereof wherein said chelator comprises ethylenediamine disuccinic acid (EDDS), wherein said encapsulated benefit agent comprises a) perfume microcapsule, said perfume microcapsule comprising a core and a housing encapsulating said core, said housing comprising crosslinked formaldehyde melamine; b) a binder. 2. Composition for releasing the benefit agent according to Petition 870190034139, of 10/04/2019, p. 8/13 2/2 with claim 1, characterized by the fact that: a) said encapsulated benefit agent comprises a perfume microcapsule, said perfume microcapsule comprising a carcass, said carcass comprising crosslinked formaldehyde melamine and a chelating agent; b) said plasticizer comprises water; c) said binder is selected from the group consisting of CMC, alginate, starches, polyvinyl alcohols, polyethylene oxide, polyvinyl pyrrolidone, chitosan and / or natural gums, cross-linked polyacrylates, waxes, polyethylene glycols, alcohol ethoxylates, surfactants, and mixtures thereof, and d) said dust removal agent is selected from the group consisting of silicas, zeolites, amorphous aluminum silicates, clays, starches, celluloses, water-soluble salts, polysaccharides, and mixtures thereof. 3. Product intended for the consumer, characterized by the fact that it comprises the composition for releasing the benefit agent as defined in claim 1 or 2, and a product auxiliary for the consumer, said product auxiliary for the consumer preferably comprising a material selected from the group consisting of polymers, surfactants, builders, chelating agents, dye transfer inhibiting agents, dispersants, enzymes and enzyme stabilizers, catalytic materials, bleach activators, polymer dispersing agents, dirt removal / anti-redeposition agents clay, whitening, foam suppressants, dyes, additional perfume and perfume release systems, structural elastic agents, fabric softeners, vehicles, hydrotropes, processing auxiliary elements and / or pigments, and mixtures thereof. 4. Product intended for the consumer, characterized by the fact that it comprises, based on the total weight of the product intended for the consumer, from 0.1% to 20% of the composition for release of the benefit agent as defined in claim 1 or 2.