BR0211315A - Uso de derivados de ácido 2,5-diidroxibenzeno-sulfÈnicos na elaboração de um produto medicinal para aumentar o efeito de outros medicamentos utilizados no tratamento de disfunção erétil - Google Patents
Uso de derivados de ácido 2,5-diidroxibenzeno-sulfÈnicos na elaboração de um produto medicinal para aumentar o efeito de outros medicamentos utilizados no tratamento de disfunção erétilInfo
- Publication number
- BR0211315A BR0211315A BR0211315-5A BR0211315A BR0211315A BR 0211315 A BR0211315 A BR 0211315A BR 0211315 A BR0211315 A BR 0211315A BR 0211315 A BR0211315 A BR 0211315A
- Authority
- BR
- Brazil
- Prior art keywords
- increase
- acid derivatives
- effect
- medicinal product
- manufacture
- Prior art date
Links
- 229940126601 medicinal product Drugs 0.000 title abstract 4
- 230000000694 effects Effects 0.000 title abstract 3
- IKQCSJBQLWJEPU-UHFFFAOYSA-N 2,5-dihydroxybenzenesulfonic acid Chemical class OC1=CC=C(O)C(S(O)(=O)=O)=C1 IKQCSJBQLWJEPU-UHFFFAOYSA-N 0.000 title abstract 2
- 208000010228 Erectile Dysfunction Diseases 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 201000001881 impotence Diseases 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- BNRNXUUZRGQAQC-UHFFFAOYSA-N sildenafil Chemical compound CCCC1=NN(C)C(C(N2)=O)=C1N=C2C(C(=CC=1)OCC)=CC=1S(=O)(=O)N1CCN(C)CC1 BNRNXUUZRGQAQC-UHFFFAOYSA-N 0.000 abstract 2
- ZOOGRGPOEVQQDX-UUOKFMHZSA-N 3',5'-cyclic GMP Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-UUOKFMHZSA-N 0.000 abstract 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 abstract 1
- SNIOPGDIGTZGOP-UHFFFAOYSA-N Nitroglycerin Chemical compound [O-][N+](=O)OCC(O[N+]([O-])=O)CO[N+]([O-])=O SNIOPGDIGTZGOP-UHFFFAOYSA-N 0.000 abstract 1
- SECKRCOLJRRGGV-UHFFFAOYSA-N Vardenafil Chemical compound CCCC1=NC(C)=C(C(N=2)=O)N1NC=2C(C(=CC=1)OCC)=CC=1S(=O)(=O)N1CCN(CC)CC1 SECKRCOLJRRGGV-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- HSNWZBCBUUSSQD-UHFFFAOYSA-N amyl nitrate Chemical compound CCCCCO[N+]([O-])=O HSNWZBCBUUSSQD-UHFFFAOYSA-N 0.000 abstract 1
- VMWNQDUVQKEIOC-CYBMUJFWSA-N apomorphine Chemical compound C([C@H]1N(C)CC2)C3=CC=C(O)C(O)=C3C3=C1C2=CC=C3 VMWNQDUVQKEIOC-CYBMUJFWSA-N 0.000 abstract 1
- 229960004046 apomorphine Drugs 0.000 abstract 1
- YEESUBCSWGVPCE-UHFFFAOYSA-N azanylidyneoxidanium iron(2+) pentacyanide Chemical compound [Fe++].[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.N#[O+] YEESUBCSWGVPCE-UHFFFAOYSA-N 0.000 abstract 1
- ZOOGRGPOEVQQDX-UHFFFAOYSA-N cyclic GMP Natural products O1C2COP(O)(=O)OC2C(O)C1N1C=NC2=C1NC(N)=NC2=O ZOOGRGPOEVQQDX-UHFFFAOYSA-N 0.000 abstract 1
- 230000001856 erectile effect Effects 0.000 abstract 1
- 229960003711 glyceryl trinitrate Drugs 0.000 abstract 1
- LBHIOVVIQHSOQN-UHFFFAOYSA-N nicorandil Chemical compound [O-][N+](=O)OCCNC(=O)C1=CC=CN=C1 LBHIOVVIQHSOQN-UHFFFAOYSA-N 0.000 abstract 1
- 229960002497 nicorandil Drugs 0.000 abstract 1
- 229910017604 nitric acid Inorganic materials 0.000 abstract 1
- 229960002460 nitroprusside Drugs 0.000 abstract 1
- 230000018052 penile erection Effects 0.000 abstract 1
- 239000002590 phosphodiesterase V inhibitor Substances 0.000 abstract 1
- 229960003310 sildenafil Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 229960002381 vardenafil Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200101535A ES2180446B1 (es) | 2001-07-02 | 2001-07-02 | Empleo de derivados de acidos 2,5-dihidroxibencenosulfonicos en la elaboracion de un medicamento para potenciar el efecto de otros farmacos en el tratamiento de la disfuncion erectil. |
| PCT/ES2002/000325 WO2003004097A1 (es) | 2001-07-02 | 2002-07-01 | Empleo de derivados de ácidos 2,5-dihidroxibencenosulfónicos en la elaboración de un medicamento para potenciar el efecto de otros fármacos en el tratamiento de la disfunción eréctil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0211315A true BR0211315A (pt) | 2004-09-28 |
Family
ID=8498259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0211315-5A BR0211315A (pt) | 2001-07-02 | 2002-07-01 | Uso de derivados de ácido 2,5-diidroxibenzeno-sulfÈnicos na elaboração de um produto medicinal para aumentar o efeito de outros medicamentos utilizados no tratamento de disfunção erétil |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20040143010A1 (enExample) |
| EP (1) | EP1413332B1 (enExample) |
| JP (1) | JP2005501031A (enExample) |
| AR (1) | AR036124A1 (enExample) |
| AT (1) | ATE419012T1 (enExample) |
| BR (1) | BR0211315A (enExample) |
| CA (1) | CA2453572A1 (enExample) |
| DE (1) | DE60230629D1 (enExample) |
| ES (2) | ES2180446B1 (enExample) |
| HU (1) | HUP0400924A3 (enExample) |
| MX (1) | MXPA04000007A (enExample) |
| NO (1) | NO20040007L (enExample) |
| PL (1) | PL367766A1 (enExample) |
| WO (1) | WO2003004097A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2208123A1 (es) * | 2002-11-29 | 2004-06-01 | Laboratorios Del Dr. Esteve, S.A. | Uso de los compuestos 2,5-dihidroxibencenosulfonicos para la fabricacion de un medicamento. |
| ES2222831B2 (es) * | 2003-07-30 | 2006-02-16 | Laboratorios Del Dr. Esteve, S.A. | Combinacion de principio activo que comprende un compuesto 2,5-dihidroxibencenosulfonico y un modulador de los canales de k+. |
| RU2281101C2 (ru) * | 2004-10-01 | 2006-08-10 | Юрий Михайлович Есилевский | Способ лечения больных хроническим простатитом |
| EP1676573A1 (en) * | 2004-12-30 | 2006-07-05 | Laboratorios Del Dr. Esteve, S.A. | Phamaceutical composition comprising a 2,5-dihydroxybenzenesulfonic-compound, a potassium ion channel modulator and a phosphodiesterase type 5 inhibitor |
| EP2669269B1 (en) | 2005-05-27 | 2019-05-22 | The University of North Carolina At Chapel Hill | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications |
| EP2467173B8 (en) | 2009-08-21 | 2019-06-19 | Novan, Inc. | Wound dressings, methods of using the same and methods of forming the same |
| WO2011022652A1 (en) | 2009-08-21 | 2011-02-24 | Novan, Inc. | Topical gels |
| US8591876B2 (en) | 2010-12-15 | 2013-11-26 | Novan, Inc. | Methods of decreasing sebum production in the skin |
| WO2012118819A2 (en) | 2011-02-28 | 2012-09-07 | Novan, Inc. | Nitric oxide-releasing s-nitrosothiol-modified silica particles and methods of making the same |
| CN109678764A (zh) * | 2018-12-05 | 2019-04-26 | 湖北广辰药业有限公司 | 一种羟苯双磺酸及其钙盐和制备方法 |
| US11977085B1 (en) | 2023-09-05 | 2024-05-07 | Elan Ehrlich | Date rape drug detection device and method of using same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3681503A (en) * | 1970-04-17 | 1972-08-01 | Om Lab Sa | Method for combating disturbances of the lipid content of the blood |
| US4252821A (en) * | 1979-12-07 | 1981-02-24 | Laboratoires Om Societe Anonyme | Method for treating ulcers |
| US4511557A (en) * | 1981-08-24 | 1985-04-16 | Gauri Kailash Kumar | Pharmaceutical composition |
| US4513007A (en) * | 1983-05-03 | 1985-04-23 | Laboratoires Om Sa | Method for treating heart disease |
| RU1776408C (ru) * | 1990-08-13 | 1992-11-23 | Одесский Медицинский Институт Им.Н.И.Пирогова | Способ лечени гломерулонефрита |
| AU715600B2 (en) * | 1996-04-03 | 2000-02-03 | Laboratorios Del Dr. Esteve, S.A. | Use of 2,5-dihydroxybenzenesulfonic derivatives for the manufacture of medicaments intended for the normalization of the endothelial function, for the treatment of sexual dysfunction and vascular complications of diabetes, as well as vascular disorders of endothelial origin |
| HU225149B1 (en) * | 1996-12-30 | 2006-07-28 | Teva Gyogyszergyar Zrt | Use of dobesilate salts for the manufacture of medicaments for the treatment or prevention of embryonic retardation or discordance |
| US6403643B1 (en) * | 1997-04-03 | 2002-06-11 | Laboratories Del Dr. Esteve, S.A. | Use of 2,5-dihydroxybenzenesulfonic derivatives for the normalization of endothelial function |
| US5994363A (en) * | 1998-08-24 | 1999-11-30 | Pentech Pharmaceuticals, Inc. | Amelioration of apomorphine adverse effects |
| US6087362A (en) * | 1999-03-16 | 2000-07-11 | Pentech Pharmaceuticals, Inc. | Apomorphine and sildenafil composition |
-
2001
- 2001-07-02 ES ES200101535A patent/ES2180446B1/es not_active Expired - Fee Related
-
2002
- 2002-07-01 HU HU0400924A patent/HUP0400924A3/hu unknown
- 2002-07-01 WO PCT/ES2002/000325 patent/WO2003004097A1/es not_active Ceased
- 2002-07-01 AT AT02745439T patent/ATE419012T1/de not_active IP Right Cessation
- 2002-07-01 BR BR0211315-5A patent/BR0211315A/pt not_active IP Right Cessation
- 2002-07-01 PL PL02367766A patent/PL367766A1/xx not_active Application Discontinuation
- 2002-07-01 EP EP02745439A patent/EP1413332B1/en not_active Expired - Lifetime
- 2002-07-01 US US10/482,457 patent/US20040143010A1/en not_active Abandoned
- 2002-07-01 CA CA002453572A patent/CA2453572A1/en not_active Abandoned
- 2002-07-01 AR ARP020102472A patent/AR036124A1/es not_active Application Discontinuation
- 2002-07-01 ES ES02745439T patent/ES2318023T3/es not_active Expired - Lifetime
- 2002-07-01 DE DE60230629T patent/DE60230629D1/de not_active Expired - Fee Related
- 2002-07-01 JP JP2003510106A patent/JP2005501031A/ja active Pending
- 2002-07-01 MX MXPA04000007A patent/MXPA04000007A/es not_active Application Discontinuation
-
2004
- 2004-01-02 NO NO20040007A patent/NO20040007L/no not_active Application Discontinuation
-
2006
- 2006-12-19 US US11/641,269 patent/US20070197543A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20040143010A1 (en) | 2004-07-22 |
| ES2180446A1 (es) | 2003-02-01 |
| PL367766A1 (en) | 2005-03-07 |
| ES2180446B1 (es) | 2004-01-16 |
| HUP0400924A2 (hu) | 2004-07-28 |
| MXPA04000007A (es) | 2004-05-21 |
| ES2318023T3 (es) | 2009-05-01 |
| NO20040007L (no) | 2004-02-23 |
| DE60230629D1 (de) | 2009-02-12 |
| CA2453572A1 (en) | 2003-01-16 |
| US20070197543A1 (en) | 2007-08-23 |
| ATE419012T1 (de) | 2009-01-15 |
| EP1413332A1 (en) | 2004-04-28 |
| AR036124A1 (es) | 2004-08-11 |
| EP1413332B1 (en) | 2008-12-31 |
| WO2003004097A1 (es) | 2003-01-16 |
| HUP0400924A3 (en) | 2007-11-28 |
| JP2005501031A (ja) | 2005-01-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0205391A (pt) | Hidrato a de aripiprazol, processo para a preparação do hidrato a, substância de medicamento de aripiprazol de hogroscopicidade baixa, cristais de anidro de aripiprazol b, processos para a preparação de cristais de anidrido de aripiprazol b e para a preparação de uma preparação oral sólida farmacêutica, uso de cristais de anidrido de aripiprazol b, medicamento para tratar a esquizofrenia ou os sintomas associados com a esquizofrenia, processo para preparação de grânulos, preparação oral sólida farmacêutica, cristais de anidrido de aripiprazol c até g, processo para a preparação de cristais de anidridro de aripiprazol c até g, e, composição farmacêutica. | |
| CY1118059T1 (el) | Συνθεσεις αντιλοιμωδων βασει λιπιδιων για αγωγη πνευμονικων λοιμωξεων | |
| BR0308196A (pt) | Composto, formulação farmacêutica, uso de um composto, métodos de prevenção e/ou tratamento de condições associadas com a glicogênio sintase cinase-3, e de doenças, e, processo para a preparação de um composto | |
| BRPI0415753A (pt) | método para tratamento e prevenção da inflamação respiratória com um inibidor de ciclooxigenase-2 em associação com um inibidor de fosfodiesterase 4 e composições que os contêm | |
| BR0010456A (pt) | Uso de xenÈnio para tratar neurointoxicações, preparação inalável e método para produzir uma preparação inalável | |
| AR035936A1 (es) | Inhibidores de metaloproteinasas de matriz piridinica, derivados de piridina, composiciones farmaceuticas y usos de los mismos en la fabricacion de medicamentos | |
| CL2010000434A1 (es) | Uso de una composicion farmaceutica que comprende vitamina b12 y acido n-(8-(2-hidroxibenzoil)animo) caprilico o sus sales para preparar un medicamento util en el tratamiento de la deficiencia de vitamina b12; composicion farmaceutica. | |
| PT88930A (pt) | Processo para a preparacao de novos analogos de nucleosidos e de composicoes farmaceuticas que os contem | |
| ES2178048T3 (es) | Uso de rifaximina como medicamento para el tratamiento de diarrea por criptosporidiosis. | |
| KR910700045A (ko) | Hiv 감염 관련 질병의 치료 | |
| BRPI0411451A (pt) | formas de dosagens orais de memantina | |
| AR006401A1 (es) | Compuestos de pirrolopirrolona, una composicion farmaceutica que los contiene, su uso en la fabricacion de un medicamento y en terapia, procesospara su preparación y compuestos intermediarios para dichos procesos. | |
| BRPI0510080A (pt) | combinações farmacêuticas contendo benzoxazina para tratar doenças respiratórias | |
| ES2462553A1 (es) | Composición para mejora del bienestar sexual | |
| BRPI0208468B8 (pt) | camsilato de amlodipina e processo para sua preparação | |
| BRPI0015939B8 (pt) | sistema terapêutico transdérmico com estabilidade aperfeiçoada e processo para a sua preparação | |
| ES2180446B1 (es) | Empleo de derivados de acidos 2,5-dihidroxibencenosulfonicos en la elaboracion de un medicamento para potenciar el efecto de otros farmacos en el tratamiento de la disfuncion erectil. | |
| AR035889A1 (es) | Citrato de 5,7,14-triazatetraciclo[10.3.1.02,11.04,9]hexadeca-2(11),3,5,7,9- pentaeno y composiciones farmaceuticas que la contienen y su uso para la elaboracion de medicamentos | |
| KR970705563A (ko) | 항바이러스제로서의 4-(2-아미노-6-(시클로프로필아미노)-9H-푸린-9-일)-2-시클로펜텐-1-메탄올 숙시네이트(4-(2-Amino-6-(Cyclopropylamino)-9H-Purin-9-yl)-2-Cyclopentene-1-Methanol Succinate as Antiviral Agent) | |
| AR015668A1 (es) | Sal de hemisulfato de (1s,4r)-cis-4-[2-amino-6-(ciclopropilamino)-9h-purin-9-il]-2-ciclopenten-1-metanol y formulacion farmaceutica que la contiene | |
| Morginson | Toxic reactions accompanying penicillin therapy | |
| BR0207866A (pt) | Uso de flumazenil na preparação de um medicamento para o tratamento da dependência de cocaìna | |
| WO2002064552A8 (en) | 1g(a)-AMINO-N-HYDROXY-ACETAMIDE DERIVATIVES | |
| BRPI0509667B8 (pt) | composto, processo para a preparação de um composto de fórmula (i), medicamento e uso de um composto | |
| WO2014193269A4 (ru) | Лекарственное средство на основе дииндолилметана и его применение для лечения гриппа и респираторных вирусных инфекций |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A,7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2060 DE 29/06/2010. |
|
| B15K | Others concerning applications: alteration of classification |
Ipc: A61K 31/185 (2006.01), A61P 15/10 (2006.01) |