BR0116185A - Isolated polynucleotide, arogenate dehydrogenase enzyme, chimeric gene, expression or transformation vector, host organism, transformed plant cell, arogenate dehydrogenase enzyme preparation process, compound identification process, herbicidal compounds, herbicide tolerant plants and production process of herbicide tolerant plants. - Google Patents
Isolated polynucleotide, arogenate dehydrogenase enzyme, chimeric gene, expression or transformation vector, host organism, transformed plant cell, arogenate dehydrogenase enzyme preparation process, compound identification process, herbicidal compounds, herbicide tolerant plants and production process of herbicide tolerant plants.Info
- Publication number
- BR0116185A BR0116185A BR0116185-7A BR0116185A BR0116185A BR 0116185 A BR0116185 A BR 0116185A BR 0116185 A BR0116185 A BR 0116185A BR 0116185 A BR0116185 A BR 0116185A
- Authority
- BR
- Brazil
- Prior art keywords
- tolerant plants
- arogenate dehydrogenase
- enzymes
- herbicidal compounds
- herbicide tolerant
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
- C12Y103/01012—Prephenate dehydrogenase (1.3.1.12)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
- C12Y103/01013—Prephenate dehydrogenase (NADP+) (1.3.1.13)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Abstract
"POLINUCLEOTìDEO ISOLADO, ENZIMA COM ATIVIDADE AROGENATO DESIDROGENASE, GENE QUIMéRICO, VETOR DE EXPRESSãO OU DE TRANSFORMAçãO, ORGANISMO HOSPEDEIRO, CéLULA VEGETAL TRANSFORMADA, PROCESSO DE PREPARAçãO DE ENZIMA AROGENATO DESIDROGENASE, PROCESSO DE IDENTIFICAçãO DE UM COMPOSTO, COMPOSTOS HERBICIDAS, PLANTAS TOLERANTES A UM COMPOSTO HERBICIDA E PROCESSO DE PRODUçãO DE PLANTAS TOLERANTES A COMPOSTOS HERBICIDAS". A presente invenção tem por objeto novas enzimas que possuem uma atividade arogenato desidrogenase, em particular enzimas arogenato desidrogenase de plantas, bem como os genes que codificam essas enzimas. As enzimas arogenato desidrogenase de acordo a presente invenção catalisam a última etapa da via metabólica de biossíntese da tirosina, e constituem, como tais, alvos potenciais de herbicidas. A presente invenção trata, portanto, do processo de identificação de compostos herbicidas que têm por alvo essas enzimas, compostos herbicidas esses que impedem a biossíntese da tirosina fixando-se nas referidas enzimas. A presente invenção tem também por objeto plantas transgênicas tolerantes a compostos herbicidas que têm por alvo uma enzima envolvida na via de biossíntese da tirosina, em particular uma enzima arogenato desidrogenase. Essas plantas se tornam tolerantes por expressão em seus tecidos de uma enzima prefenato desidrogenase, enzima essa que é insensível aos referidos compostos herbicidas e permite que a planta sintetize a tirosina apesar de um tratamento pelos referido compostos herbicidas."ISOLATED POLYNUCLEOTIDE, ENZYME ACTIVITY DEHYDROGENOSIS, CHEMICAL GENE, EXPRESSION OR TRANSFORMATION VECTOR, TRANSFORMED VEGETABLE CELL, PROGRESS OF COMPLETE DEGREES, COMPUTER DEGREES, PROGENOSIS HERBICIDE AND PROCESS FOR PRODUCTION OF TOLERANT PLANTS TO HERBICIDE COMPOUNDS ". The present invention relates to novel enzymes having an arogenate dehydrogenase activity, in particular plant arogenate dehydrogenase enzymes, as well as genes encoding such enzymes. The arogenate dehydrogenase enzymes of the present invention catalyze the last step of the tyrosine biosynthetic metabolic pathway, and as such are potential herbicide targets. The present invention therefore relates to the process of identifying herbicidal compounds which target such enzymes, which herbicidal compounds prevent tyrosine biosynthesis by attaching to said enzymes. The present invention also relates to transgenic herbicide-tolerant plants which target an enzyme involved in the tyrosine biosynthesis pathway, in particular an arogenate dehydrogenase enzyme. These plants become tolerant to expression in their tissues of a enzyme prefenate dehydrogenase, which enzyme is insensitive to said herbicidal compounds and allows the plant to synthesize tyrosine despite treatment by said herbicidal compounds.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0015723A FR2817557B1 (en) | 2000-12-05 | 2000-12-05 | NEW TARGETS FOR HERBICIDES AND TRANSGENIC PLANTS RESISTANT TO THESE HERBICIDES |
PCT/FR2001/003832 WO2002046441A2 (en) | 2000-12-05 | 2001-12-05 | Targets for herbicides and transgenic plants resistant to said herbicides |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0116185A true BR0116185A (en) | 2003-11-25 |
Family
ID=8857237
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0116185-7A BR0116185A (en) | 2000-12-05 | 2001-12-05 | Isolated polynucleotide, arogenate dehydrogenase enzyme, chimeric gene, expression or transformation vector, host organism, transformed plant cell, arogenate dehydrogenase enzyme preparation process, compound identification process, herbicidal compounds, herbicide tolerant plants and production process of herbicide tolerant plants. |
Country Status (8)
Country | Link |
---|---|
US (3) | US7279302B2 (en) |
EP (2) | EP1862553A3 (en) |
CN (2) | CN1543506A (en) |
AU (1) | AU1617002A (en) |
BR (1) | BR0116185A (en) |
FR (1) | FR2817557B1 (en) |
MX (1) | MXPA03004945A (en) |
WO (1) | WO2002046441A2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6872815B1 (en) | 2000-10-14 | 2005-03-29 | Calgene Llc | Nucleic acid sequences to proteins involved in tocopherol synthesis |
US6841717B2 (en) | 2000-08-07 | 2005-01-11 | Monsanto Technology, L.L.C. | Methyl-D-erythritol phosphate pathway genes |
US7238855B2 (en) * | 2001-05-09 | 2007-07-03 | Monsanto Technology Llc | TyrA genes and uses thereof |
EP1950305A1 (en) * | 2001-05-09 | 2008-07-30 | Monsanto Technology, LLC | Tyr a genes and uses thereof |
FR2844142B1 (en) * | 2002-09-11 | 2007-08-17 | Bayer Cropscience Sa | TRANSFORMED PLANTS WITH ENHANCED PRENYLQUINON BIOSYNTHESIS |
US8709772B2 (en) * | 2008-01-03 | 2014-04-29 | Verenium Corporation | Transferases and oxidoreductases, nucleic acids encoding them and methods for making and using them |
US20220275406A1 (en) * | 2019-08-14 | 2022-09-01 | Oxford University Innovation Limited | Membrane Transport Protein and Uses Thereof |
CN113061619B (en) * | 2021-04-30 | 2022-06-24 | 中国烟草总公司郑州烟草研究院 | Mutant gene TyrA related to phenol release amount of smoke |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5187071A (en) * | 1988-07-15 | 1993-02-16 | Fischer Randy S | Method for the selective control of weeds, pests, and microbes |
US5792921A (en) * | 1992-02-14 | 1998-08-11 | Londesborough; John | Increasing the trehalose content of organisms by transforming them with combinations of the structural genes for trehalose synthase |
FR2734842B1 (en) * | 1995-06-02 | 1998-02-27 | Rhone Poulenc Agrochimie | DNA SEQUENCE OF A HYDROXY-PHENYL PYRUVATE DIOXYGENASE GENE AND OBTAINING PLANTS CONTAINING A HYDROXY-PHENYL PYRUVATE DIOXYGENASE GENE, TOLERANT TO CERTAIN HERBICIDES |
US6653530B1 (en) * | 1998-02-13 | 2003-11-25 | Calgene Llc | Methods for producing carotenoid compounds, tocopherol compounds, and specialty oils in plant seeds |
US6627798B2 (en) * | 1998-12-04 | 2003-09-30 | E.I. Du Pont De Nemours And Company | Aromatic amino acid biosynthetic enzymes |
AR030430A1 (en) * | 2000-06-29 | 2003-08-20 | Sungene Gmbh & Co Kgaa | PROCEDURE FOR THE OBTAINING OF FINE CHEMICALS BY CULTURE OF ORGANISMS THAT PRESENT A MODIFIED SHIQUIMATE ROUTE, NUCLEINIC ACID COMPOSITION, USE OF SUCH NUCLEINIC ACID FOR THE OBTAINING OF TRANSGENIC PLANTS, GENETICALLY PRODUCED PROCEDURE ORGANISM |
US7238855B2 (en) * | 2001-05-09 | 2007-07-03 | Monsanto Technology Llc | TyrA genes and uses thereof |
-
2000
- 2000-12-05 FR FR0015723A patent/FR2817557B1/en not_active Expired - Fee Related
-
2001
- 2001-12-05 CN CNA018219616A patent/CN1543506A/en active Pending
- 2001-12-05 CN CNA2008101767068A patent/CN101560499A/en active Pending
- 2001-12-05 MX MXPA03004945A patent/MXPA03004945A/en active IP Right Grant
- 2001-12-05 AU AU1617002A patent/AU1617002A/en active Pending
- 2001-12-05 WO PCT/FR2001/003832 patent/WO2002046441A2/en not_active Application Discontinuation
- 2001-12-05 BR BR0116185-7A patent/BR0116185A/en not_active Application Discontinuation
- 2001-12-05 US US10/433,556 patent/US7279302B2/en not_active Expired - Lifetime
- 2001-12-05 EP EP07115389A patent/EP1862553A3/en not_active Ceased
- 2001-12-05 EP EP01999658A patent/EP1339860A2/en not_active Ceased
-
2007
- 2007-09-14 US US11/855,607 patent/US20080148431A1/en not_active Abandoned
-
2018
- 2018-04-27 US US15/965,441 patent/US20190071649A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20190071649A1 (en) | 2019-03-07 |
CN1543506A (en) | 2004-11-03 |
EP1862553A2 (en) | 2007-12-05 |
US20040117872A1 (en) | 2004-06-17 |
CN101560499A (en) | 2009-10-21 |
MXPA03004945A (en) | 2004-05-04 |
EP1862553A3 (en) | 2008-04-09 |
US7279302B2 (en) | 2007-10-09 |
WO2002046441A2 (en) | 2002-06-13 |
WO2002046441A3 (en) | 2003-02-20 |
US20080148431A1 (en) | 2008-06-19 |
FR2817557A1 (en) | 2002-06-07 |
AU1617002A (en) | 2002-06-18 |
EP1339860A2 (en) | 2003-09-03 |
FR2817557B1 (en) | 2005-05-06 |
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