BR0112299A - Antifungal and / or antibacterial peptides, their preparation methods and compositions containing them - Google Patents

Antifungal and / or antibacterial peptides, their preparation methods and compositions containing them

Info

Publication number
BR0112299A
BR0112299A BR0112299-1A BR0112299A BR0112299A BR 0112299 A BR0112299 A BR 0112299A BR 0112299 A BR0112299 A BR 0112299A BR 0112299 A BR0112299 A BR 0112299A
Authority
BR
Brazil
Prior art keywords
amino acid
antifungal
acids
peptides
small
Prior art date
Application number
BR0112299-1A
Other languages
Portuguese (pt)
Inventor
Jean-Luc Dimarq
Mich Le Legrain
Laure Menin
Original Assignee
Entomed S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0009248A external-priority patent/FR2811665B1/en
Application filed by Entomed S A filed Critical Entomed S A
Publication of BR0112299A publication Critical patent/BR0112299A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Insects & Arthropods (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

Abstract

The invention concerns peptides derived from helimomicine by substitution of one or several amnio acids, characterised in that the peptides correspond to formula (I) : X1, X2, X3, X4, X5, X6, C7, X8, X9, X10, X11, X12, X13, X14, X15, X16, X17, C18, X19, X20, X21, C22, X23, X 24, X25, X26, X27, X28, X29, X30, X31, X32, X33, X34, X35, X36, X37, X38, X39, C40, X41, C42, X43, X44 wherein X1, X17, X21, X43 are amino acids; X16, X44 are small polar amino acids; X19 is a large polar amino acid; X36 is a small or lightly hydophobic amino acid; X38 is a lightly hydrophobic or small amino acid; the substitutions being such that: at least one of X1, X17, X21, X43 is a basic or polar, advantageously large polar amino acid, and/or at least one of the amnio acids X16, X44 is a basic amino acid or a large polar amino acid, and/or X19 is a basic amino acid, and/or at least one of the amino acids X36, X38 is a strongly hydrophobic amino acid. The invention also concerns antifungal and/or antibacterial compositions comprising at least one of the peptides.
BR0112299-1A 2000-07-13 2001-07-05 Antifungal and / or antibacterial peptides, their preparation methods and compositions containing them BR0112299A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0009248A FR2811665B1 (en) 2000-07-13 2000-07-13 ANTIFUNGAL AND / OR ANTIBACTERIAL PEPTIDES, THEIR PREPARATIONS AND THE COMPOSITIONS CONTAINING THEM
FR0011949A FR2811666B1 (en) 2000-07-13 2000-09-19 ANTIFUNGAL AND / OR ANTIBACTERIAL PEPTIDES, PREPARATIONS THEREOF AND COMPOSITIONS CONTAINING SAME
PCT/FR2001/002164 WO2002006324A2 (en) 2000-07-13 2001-07-05 Antifungal and/or antibacterial peptides, preparation methods and composition containing same

Publications (1)

Publication Number Publication Date
BR0112299A true BR0112299A (en) 2003-06-10

Family

ID=26212534

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0112299-1A BR0112299A (en) 2000-07-13 2001-07-05 Antifungal and / or antibacterial peptides, their preparation methods and compositions containing them

Country Status (15)

Country Link
US (1) US20030208035A1 (en)
EP (1) EP1299416B1 (en)
JP (1) JP2004537960A (en)
KR (1) KR20030032997A (en)
CN (1) CN1441809A (en)
AT (1) ATE323104T1 (en)
AU (1) AU2002222936A1 (en)
BR (1) BR0112299A (en)
CA (1) CA2415481A1 (en)
DE (1) DE60118746D1 (en)
FR (1) FR2811666B1 (en)
IL (1) IL153635A0 (en)
NZ (1) NZ523497A (en)
RU (1) RU2003104278A (en)
WO (1) WO2002006324A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3141559A1 (en) * 2004-08-18 2017-03-15 Novabiotics Limited Antimicrobial peptides
AU2011235933B2 (en) * 2004-08-18 2012-06-07 Novabiotics Limited Antimicrobial peptides comprising an arginine- and/or lysine-containing motif
KR101653141B1 (en) * 2014-05-28 2016-09-01 주식회사 베네팜 Novel analogues of antibacterial peptide derived from halocynthia aurantium and the use thereof
AU2018304493B2 (en) 2017-07-17 2022-07-28 Linnane Pharma Ab Peptides with antibiotic potential against Mycobacterium tuberculosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2695392B1 (en) * 1992-09-04 1994-10-14 Centre Nat Rech Scient Peptides having in particular antibacterial properties, their process of obtaining, and their biological applications.
FR2777568B1 (en) * 1998-04-15 2002-10-31 Rhone Poulenc Agrochimie GENE ENCODING HELIOMICIN, PROTEIN OBTAINED, VECTOR CONTAINING SAME, TRANSFORMED ORGANISMS OBTAINED, AND PREPARATION METHOD

Also Published As

Publication number Publication date
NZ523497A (en) 2004-04-30
ATE323104T1 (en) 2006-04-15
WO2002006324A2 (en) 2002-01-24
KR20030032997A (en) 2003-04-26
EP1299416A2 (en) 2003-04-09
CN1441809A (en) 2003-09-10
JP2004537960A (en) 2004-12-24
AU2002222936A1 (en) 2002-01-30
RU2003104278A (en) 2004-08-20
US20030208035A1 (en) 2003-11-06
FR2811666B1 (en) 2005-04-01
FR2811666A1 (en) 2002-01-18
CA2415481A1 (en) 2002-01-24
EP1299416B1 (en) 2006-04-12
DE60118746D1 (en) 2006-05-24
IL153635A0 (en) 2003-07-06
WO2002006324A3 (en) 2002-05-23

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ,7A E 8A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2016 DE 25/08/2009.