AU2002222936A1 - Antifungal and/or antibacterial peptides, preparation methods and composition containing same - Google Patents

Antifungal and/or antibacterial peptides, preparation methods and composition containing same

Info

Publication number
AU2002222936A1
AU2002222936A1 AU2002222936A AU2293602A AU2002222936A1 AU 2002222936 A1 AU2002222936 A1 AU 2002222936A1 AU 2002222936 A AU2002222936 A AU 2002222936A AU 2293602 A AU2293602 A AU 2293602A AU 2002222936 A1 AU2002222936 A1 AU 2002222936A1
Authority
AU
Australia
Prior art keywords
amino acid
antifungal
acids
composition containing
preparation methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002222936A
Inventor
Jean-Luc Dimarcq
Michele Legrain
Laure Menin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ENTOMED (S A)
Original Assignee
Entomed S A
ENTOMED (S A)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0009248A external-priority patent/FR2811665B1/en
Application filed by Entomed S A, ENTOMED (S A) filed Critical Entomed S A
Publication of AU2002222936A1 publication Critical patent/AU2002222936A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention concerns peptides derived from helimomicine by substitution of one or several amnio acids, characterised in that the peptides correspond to formula (I) : X1, X2, X3, X4, X5, X6, C7, X8, X9, X10, X11, X12, X13, X14, X15, X16, X17, C18, X19, X20, X21, C22, X23, X 24, X25, X26, X27, X28, X29, X30, X31, X32, X33, X34, X35, X36, X37, X38, X39, C40, X41, C42, X43, X44 wherein X1, X17, X21, X43 are amino acids; X16, X44 are small polar amino acids; X19 is a large polar amino acid; X36 is a small or lightly hydophobic amino acid; X38 is a lightly hydrophobic or small amino acid; the substitutions being such that: at least one of X1, X17, X21, X43 is a basic or polar, advantageously large polar amino acid, and/or at least one of the amnio acids X16, X44 is a basic amino acid or a large polar amino acid, and/or X19 is a basic amino acid, and/or at least one of the amino acids X36, X38 is a strongly hydrophobic amino acid. The invention also concerns antifungal and/or antibacterial compositions comprising at least one of the peptides.
AU2002222936A 2000-07-13 2001-07-05 Antifungal and/or antibacterial peptides, preparation methods and composition containing same Abandoned AU2002222936A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
FR0009248A FR2811665B1 (en) 2000-07-13 2000-07-13 ANTIFUNGAL AND / OR ANTIBACTERIAL PEPTIDES, THEIR PREPARATIONS AND THE COMPOSITIONS CONTAINING THEM
FR0009248 2000-07-13
FR0011949A FR2811666B1 (en) 2000-07-13 2000-09-19 ANTIFUNGAL AND / OR ANTIBACTERIAL PEPTIDES, PREPARATIONS THEREOF AND COMPOSITIONS CONTAINING SAME
FR0011949 2000-09-19
PCT/FR2001/002164 WO2002006324A2 (en) 2000-07-13 2001-07-05 Antifungal and/or antibacterial peptides, preparation methods and composition containing same

Publications (1)

Publication Number Publication Date
AU2002222936A1 true AU2002222936A1 (en) 2002-01-30

Family

ID=26212534

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002222936A Abandoned AU2002222936A1 (en) 2000-07-13 2001-07-05 Antifungal and/or antibacterial peptides, preparation methods and composition containing same

Country Status (15)

Country Link
US (1) US20030208035A1 (en)
EP (1) EP1299416B1 (en)
JP (1) JP2004537960A (en)
KR (1) KR20030032997A (en)
CN (1) CN1441809A (en)
AT (1) ATE323104T1 (en)
AU (1) AU2002222936A1 (en)
BR (1) BR0112299A (en)
CA (1) CA2415481A1 (en)
DE (1) DE60118746D1 (en)
FR (1) FR2811666B1 (en)
IL (1) IL153635A0 (en)
NZ (1) NZ523497A (en)
RU (1) RU2003104278A (en)
WO (1) WO2002006324A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011235933B2 (en) * 2004-08-18 2012-06-07 Novabiotics Limited Antimicrobial peptides comprising an arginine- and/or lysine-containing motif
CN103360485A (en) 2004-08-18 2013-10-23 诺瓦生命科学有限公司 Antimicrobial peptides comprising an arginine-and/or lysine-containing motif
KR101653141B1 (en) * 2014-05-28 2016-09-01 주식회사 베네팜 Novel analogues of antibacterial peptide derived from halocynthia aurantium and the use thereof
AU2018304493B2 (en) 2017-07-17 2022-07-28 Linnane Pharma Ab Peptides with antibiotic potential against Mycobacterium tuberculosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2695392B1 (en) * 1992-09-04 1994-10-14 Centre Nat Rech Scient Peptides having in particular antibacterial properties, their process of obtaining, and their biological applications.
FR2777568B1 (en) * 1998-04-15 2002-10-31 Rhone Poulenc Agrochimie GENE ENCODING HELIOMICIN, PROTEIN OBTAINED, VECTOR CONTAINING SAME, TRANSFORMED ORGANISMS OBTAINED, AND PREPARATION METHOD

Also Published As

Publication number Publication date
EP1299416B1 (en) 2006-04-12
BR0112299A (en) 2003-06-10
ATE323104T1 (en) 2006-04-15
FR2811666B1 (en) 2005-04-01
JP2004537960A (en) 2004-12-24
KR20030032997A (en) 2003-04-26
WO2002006324A3 (en) 2002-05-23
EP1299416A2 (en) 2003-04-09
CA2415481A1 (en) 2002-01-24
CN1441809A (en) 2003-09-10
WO2002006324A2 (en) 2002-01-24
RU2003104278A (en) 2004-08-20
IL153635A0 (en) 2003-07-06
US20030208035A1 (en) 2003-11-06
NZ523497A (en) 2004-04-30
FR2811666A1 (en) 2002-01-18
DE60118746D1 (en) 2006-05-24

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application