BR0106715A - Corantes marcadores nir estáveis na base de polimetinas de benzopirilio - Google Patents

Corantes marcadores nir estáveis na base de polimetinas de benzopirilio

Info

Publication number
BR0106715A
BR0106715A BR0106715-0A BR0106715A BR0106715A BR 0106715 A BR0106715 A BR 0106715A BR 0106715 A BR0106715 A BR 0106715A BR 0106715 A BR0106715 A BR 0106715A
Authority
BR
Brazil
Prior art keywords
nir
dyes based
marker dyes
polymethylines
benzopyryl
Prior art date
Application number
BR0106715-0A
Other languages
English (en)
Inventor
Peter Czerney
Wilhelm Frank
Frank Lehmann
Bernd Schweder
Matthias Wenzel
Original Assignee
Dyomics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2000125820 external-priority patent/DE10025820C2/de
Application filed by Dyomics Gmbh filed Critical Dyomics Gmbh
Publication of BR0106715A publication Critical patent/BR0106715A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/0066—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of a carbocyclic ring,(e.g. benzene, naphtalene, cyclohexene, cyclobutenene-quadratic acid)
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Polymerisation Methods In General (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Indole Compounds (AREA)

Abstract

"CORANTES MARCADORES NIR ESTáVEIS NA BASE DE POLIMETINAS DE BENZOPIRìLIO". o invento se refere aos assim denominados corantes-marcadores NIR baseados sobre Polimetinas, para a utilização em processos óticos, especialmente os ótico-fluorescentes de determinação e comprovação, por exemplo, na área da Medicina, na Indústria Farmacéutica bem como em Ciências Biológicas, Ciências de Materiais e do Meio Ambiente; a tarefa proposta era a de produzir corantes-marcadores NIR em base de Polimetinas com elevada fotoestabilidade e estabilidade de armezenagem, bem como elevado rendimento de fluorescência, os quais podem ser estimulados à fluorescência da forma mais simples possível através de radiação laser na área visível ou na área espectral NIR, particularmente com a luz de laser de agonio, hélio/neónio ou díodo; de acordo com o invento, serão aplicados corantes baseados em polimetinas da Fórmula Genérica (I)
BR0106715-0A 2000-05-23 2001-05-22 Corantes marcadores nir estáveis na base de polimetinas de benzopirilio BR0106715A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2000125820 DE10025820C2 (de) 2000-05-23 2000-05-23 Stabile NIR-Marker-Farbstoffe auf der Basis von Benzopyrylium-Polymethinen
DE20022277 2000-05-23
PCT/DE2001/001946 WO2001090253A1 (de) 2000-05-23 2001-05-22 Stabile nir-marker-farbstoffe auf der basis von benzopyrylium-polymethinen

Publications (1)

Publication Number Publication Date
BR0106715A true BR0106715A (pt) 2002-04-16

Family

ID=26005823

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0106715-0A BR0106715A (pt) 2000-05-23 2001-05-22 Corantes marcadores nir estáveis na base de polimetinas de benzopirilio

Country Status (9)

Country Link
US (1) US6750346B2 (pt)
EP (1) EP1283855B1 (pt)
JP (1) JP2003534435A (pt)
AT (1) ATE308589T1 (pt)
AU (1) AU6581101A (pt)
BR (1) BR0106715A (pt)
CA (1) CA2380272C (pt)
DE (1) DE50107913D1 (pt)
WO (1) WO2001090253A1 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6455734B1 (en) * 2000-08-09 2002-09-24 Magnesium Diagnostics, Inc. Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
AU2003225763A1 (en) * 2002-03-11 2003-09-29 Visen Medical, Inc. Optical imaging probes
DE10258150A1 (de) 2002-12-10 2004-07-08 Dyomics Gmbh Hydrophile Marker auf der Basis von Benzopyrylo-Polymethinen
CN1917905B (zh) * 2004-02-09 2012-01-04 诺松制药股份公司 从多糖和多核苷酸生产缀合物的方法
US7625758B2 (en) * 2005-01-26 2009-12-01 Berkelman Thomas R Coumarin-based cyanine dyes for non-specific protein binding
WO2007090468A1 (en) * 2006-02-10 2007-08-16 Agilent Technologies, Inc Protein analysis using a polymethine marker dye
GB2458016B (en) * 2006-07-28 2011-09-21 Pierce Biotechnology Inc Protein probe, compositions and methods
US7553869B2 (en) * 2006-07-28 2009-06-30 Pierce Biotechnology, Inc. Protein probe compounds, compositions, and methods
GB0615211D0 (en) * 2006-07-31 2006-09-06 Ge Healthcare Uk Ltd Asymmetric flouro-substituted polymethine dyes
US20080227209A1 (en) * 2007-03-14 2008-09-18 David Xing-Fei Deng Methods, Kits And Devices For Analysis Of Lipoprotein(a)
GB0718967D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Peptide imaging agents
GB0718957D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Optical imaging agents
US8378115B2 (en) 2007-10-02 2013-02-19 Thermo Fisher Scientific (Milwaukee) LLC Monomethine dyes
US20090236541A1 (en) * 2008-03-24 2009-09-24 General Electric Company System and Methods for Optical Imaging
US20100143258A1 (en) * 2008-12-05 2010-06-10 General Electric Company Tumor margin imaging agents
SG2014009146A (en) 2009-02-06 2014-05-29 Beth Israel Hospital Charge-balanced imaging agents
US10493169B2 (en) 2009-02-06 2019-12-03 Beth Israel Deaconess Medical Center Use of charge-balanced imaging agents for determining renal function
US9155471B2 (en) 2009-05-27 2015-10-13 Lumicell, Inc'. Methods and systems for spatially identifying abnormal cells
EP2435096A1 (en) * 2009-05-27 2012-04-04 Lumicell Diagnostics, Inc. Methods and systems for spatially identifying abnormal cells
US9314304B2 (en) 2010-12-08 2016-04-19 Lumicell, Inc. Methods and system for image guided cell ablation with microscopic resolution
CA2906056A1 (en) 2013-03-14 2014-09-25 Lumicell, Inc. Medical imaging device and methods of use
EP3606927A4 (en) * 2017-04-03 2021-03-17 Massachusetts Institute of Technology SHORTWAVE NEAR INFRARED POLYMETHINE DYES
US11292778B2 (en) 2017-06-05 2022-04-05 The Regents Of The University Of California Heterocyclyl polymethine IR chromophores
WO2021176428A1 (en) * 2020-03-06 2021-09-10 Jawaharlal Nehru Centre For Advanced Scientific Research Phenanthroline, carbazole and flavylium based cyanines and compositions and methods of making and using the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3567438A (en) 1968-03-25 1971-03-02 Eastman Kodak Co Organic photoconductors sensitized with pyrylium cyanine dyes
JPH0745630B2 (ja) * 1985-06-28 1995-05-17 富士写真フイルム株式会社 新規メチン染料
JPS63136054A (ja) 1986-11-28 1988-06-08 Fuji Photo Film Co Ltd 光感応性組成物
JPS63141068A (ja) 1986-12-04 1988-06-13 Fuji Photo Film Co Ltd 光感応性組成物
US5262549A (en) * 1991-05-30 1993-11-16 Polaroid Corporation Benzpyrylium dyes, and processes for their preparation and use
DE4341618A1 (de) 1993-12-07 1995-06-08 Univ Schiller Jena Proton-Carrier-Farbstoffe für den Nahen Infrarot-Spektralbereich
US6495692B1 (en) * 1996-12-10 2002-12-17 Abbott Laboratories Helium-neon excitable reticulocyte dyes derivable from halolepidines

Also Published As

Publication number Publication date
EP1283855B1 (de) 2005-11-02
US20020115862A1 (en) 2002-08-22
JP2003534435A (ja) 2003-11-18
AU6581101A (en) 2001-12-03
CA2380272A1 (en) 2001-11-29
ATE308589T1 (de) 2005-11-15
WO2001090253A1 (de) 2001-11-29
EP1283855A1 (de) 2003-02-19
DE50107913D1 (de) 2005-12-08
CA2380272C (en) 2011-02-15
US6750346B2 (en) 2004-06-15

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]