BR0014877A - Magnetic vehicle composed of iron and porous materials for the targeted distribution of biologically active agents - Google Patents

Magnetic vehicle composed of iron and porous materials for the targeted distribution of biologically active agents

Info

Publication number
BR0014877A
BR0014877A BR0014877-6A BR0014877A BR0014877A BR 0014877 A BR0014877 A BR 0014877A BR 0014877 A BR0014877 A BR 0014877A BR 0014877 A BR0014877 A BR 0014877A
Authority
BR
Brazil
Prior art keywords
iron
biologically active
active agents
porous materials
vehicle composed
Prior art date
Application number
BR0014877-6A
Other languages
Portuguese (pt)
Inventor
Scott Raymond Rudge
Terri Lynn Kurtz
Gilles Hugues Tapolsky
Yuhua Li
Original Assignee
Ferx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferx Inc filed Critical Ferx Inc
Publication of BR0014877A publication Critical patent/BR0014877A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5094—Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6923—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ceramic Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Paints Or Removers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"VEìCULO MAGNéTICO OBJETIVADO COMPOSTO DE FERRO E MATERIAIS POROSOS PARA A DISTRIBUIçãO OBJETIVADA DE AGENTES BIOLOGICAMENTE ATIVOS". A invenção refere-se a composições magneticamente responsivas compreendendo partículas de ferro-cerâmica usadas para transportar substâncias para diagnose e/ou tratamento médico in vivo. As partículas são formadas através de desenformação conjunta dos pós de ferro de cerâmica. Substâncias diagnósticas ou terapêuticas podem ser adsorvidas sobre as mesmas. As partículas podem ser produzidas através de trituração mecânica de uma mistura de pós de ferro e cerâmica."OBJECTIVE MAGNETIC VEHICLE COMPOSED OF IRON AND POROUS MATERIALS FOR THE OBJECTIVE DISTRIBUTION OF BIOLOGICALLY ACTIVE AGENTS". The invention relates to magnetically responsive compositions comprising ferro-ceramic particles used to transport substances for in vivo medical diagnosis and / or treatment. The particles are formed through joint deformation of the ceramic iron powders. Diagnostic or therapeutic substances can be adsorbed on them. The particles can be produced by mechanically grinding a mixture of iron and ceramic powders.

BR0014877-6A 1999-10-18 2000-10-13 Magnetic vehicle composed of iron and porous materials for the targeted distribution of biologically active agents BR0014877A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16029399P 1999-10-18 1999-10-18
PCT/US2000/028615 WO2001028587A2 (en) 1999-10-18 2000-10-13 Magnetic targeted carrier

Publications (1)

Publication Number Publication Date
BR0014877A true BR0014877A (en) 2002-06-11

Family

ID=22576298

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0014877-6A BR0014877A (en) 1999-10-18 2000-10-13 Magnetic vehicle composed of iron and porous materials for the targeted distribution of biologically active agents

Country Status (15)

Country Link
EP (1) EP1221974A2 (en)
JP (3) JP2003512336A (en)
KR (1) KR20020064299A (en)
CN (1) CN1287859C (en)
AU (1) AU772755B2 (en)
BR (1) BR0014877A (en)
CA (1) CA2387925A1 (en)
CZ (1) CZ293919B6 (en)
DE (1) DE1221974T1 (en)
ES (1) ES2182731T1 (en)
HK (1) HK1045110A1 (en)
IL (1) IL149004A0 (en)
MX (1) MXPA02003891A (en)
NZ (1) NZ518311A (en)
WO (1) WO2001028587A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9808052D0 (en) 1998-04-17 1998-06-17 Secr Defence Implants for administering substances and methods of producing implants
EP1668424A4 (en) * 2003-09-12 2009-11-25 Onkor Pharmaceuticals Inc Magnetically targetable particles comprising magnetic components and biocompatible polymers for site-specific delivery of biologically active agents
JP2007001865A (en) * 2003-09-16 2007-01-11 Ltt Bio-Pharma Co Ltd Fine particle enclosing fat-soluble medicine, method for producing the same and preparation containing the same
WO2005074991A1 (en) * 2004-02-09 2005-08-18 Kabushiki Kaisha Sangi Antitumor agent
GB0403856D0 (en) * 2004-02-20 2004-03-24 Algeta As Composition
EP1735013B1 (en) * 2004-02-20 2012-02-08 Algeta ASA Alpha- and beta-emitting hydroxyapatite particles
JP2006199810A (en) * 2005-01-20 2006-08-03 Yokohama National Univ Composite particle and method for producing the same
JP5097540B2 (en) * 2005-04-06 2012-12-12 株式会社サンギ Antitumor agent for intestinal absorption
AU2010246067B2 (en) 2009-05-04 2016-07-07 Eyepoint Pharmaceuticals Us, Inc. Porous silicon drug-eluting particles
AU2011323524B2 (en) * 2010-11-01 2016-12-08 Eyepoint Pharmaceuticals Us, Inc. Bioerodible silicon-based devices for delivery of therapeutic agents
JP6170154B2 (en) * 2012-08-28 2017-07-26 バイオキューブシステム インコーポレイテッド Porous solid phase and its use for rapid separation of biological molecules for nucleic acid amplification reactions from biological samples
AU2014235051B2 (en) 2013-03-15 2019-01-17 Eyepoint Pharmaceuticals Us, Inc. Bioerodible silicon-based compositions for delivery of therapeutic agents
JP6443907B2 (en) * 2014-02-17 2018-12-26 浩文 山本 Accumulation promoter for promoting accumulation of contrast agent in tumor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4243652A (en) * 1978-07-14 1981-01-06 The Procter & Gamble Company Gastrointestinal scanning agent
ES2066851T3 (en) * 1988-05-24 1995-03-16 Anagen Uk Ltd MAGNETICALLY ATTRIBUTABLE PARTICLES AND METHOD OF PREPARATION.
JP3436760B2 (en) * 1994-07-27 2003-08-18 ハーバート ピルグリム Superparamagnetic particles
WO1997001304A1 (en) * 1995-06-29 1997-01-16 Mallinckrodt Medical, Inc. Radiolabeled apatite particles containing a paramagnetic ion
JP3735990B2 (en) * 1997-01-28 2006-01-18 東ソー株式会社 Method for producing magnetic silica gel

Also Published As

Publication number Publication date
EP1221974A2 (en) 2002-07-17
JP2005200426A (en) 2005-07-28
CZ293919B6 (en) 2004-08-18
IL149004A0 (en) 2002-11-10
CA2387925A1 (en) 2001-04-26
CN1287859C (en) 2006-12-06
AU772755B2 (en) 2004-05-06
NZ518311A (en) 2003-10-31
AU1090501A (en) 2001-04-30
JP2003321348A (en) 2003-11-11
KR20020064299A (en) 2002-08-07
MXPA02003891A (en) 2002-12-09
WO2001028587A3 (en) 2002-01-03
CN1420787A (en) 2003-05-28
DE1221974T1 (en) 2003-02-06
WO2001028587A2 (en) 2001-04-26
CZ20021357A3 (en) 2002-11-13
ES2182731T1 (en) 2003-03-16
JP2003512336A (en) 2003-04-02
HK1045110A1 (en) 2002-11-15

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009.