BR0014877A - Magnetic vehicle composed of iron and porous materials for the targeted distribution of biologically active agents - Google Patents
Magnetic vehicle composed of iron and porous materials for the targeted distribution of biologically active agentsInfo
- Publication number
- BR0014877A BR0014877A BR0014877-6A BR0014877A BR0014877A BR 0014877 A BR0014877 A BR 0014877A BR 0014877 A BR0014877 A BR 0014877A BR 0014877 A BR0014877 A BR 0014877A
- Authority
- BR
- Brazil
- Prior art keywords
- iron
- biologically active
- active agents
- porous materials
- vehicle composed
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5094—Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6923—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ceramic Engineering (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Paints Or Removers (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"VEìCULO MAGNéTICO OBJETIVADO COMPOSTO DE FERRO E MATERIAIS POROSOS PARA A DISTRIBUIçãO OBJETIVADA DE AGENTES BIOLOGICAMENTE ATIVOS". A invenção refere-se a composições magneticamente responsivas compreendendo partículas de ferro-cerâmica usadas para transportar substâncias para diagnose e/ou tratamento médico in vivo. As partículas são formadas através de desenformação conjunta dos pós de ferro de cerâmica. Substâncias diagnósticas ou terapêuticas podem ser adsorvidas sobre as mesmas. As partículas podem ser produzidas através de trituração mecânica de uma mistura de pós de ferro e cerâmica."OBJECTIVE MAGNETIC VEHICLE COMPOSED OF IRON AND POROUS MATERIALS FOR THE OBJECTIVE DISTRIBUTION OF BIOLOGICALLY ACTIVE AGENTS". The invention relates to magnetically responsive compositions comprising ferro-ceramic particles used to transport substances for in vivo medical diagnosis and / or treatment. The particles are formed through joint deformation of the ceramic iron powders. Diagnostic or therapeutic substances can be adsorbed on them. The particles can be produced by mechanically grinding a mixture of iron and ceramic powders.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16029399P | 1999-10-18 | 1999-10-18 | |
PCT/US2000/028615 WO2001028587A2 (en) | 1999-10-18 | 2000-10-13 | Magnetic targeted carrier |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0014877A true BR0014877A (en) | 2002-06-11 |
Family
ID=22576298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0014877-6A BR0014877A (en) | 1999-10-18 | 2000-10-13 | Magnetic vehicle composed of iron and porous materials for the targeted distribution of biologically active agents |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1221974A2 (en) |
JP (3) | JP2003512336A (en) |
KR (1) | KR20020064299A (en) |
CN (1) | CN1287859C (en) |
AU (1) | AU772755B2 (en) |
BR (1) | BR0014877A (en) |
CA (1) | CA2387925A1 (en) |
CZ (1) | CZ293919B6 (en) |
DE (1) | DE1221974T1 (en) |
ES (1) | ES2182731T1 (en) |
HK (1) | HK1045110A1 (en) |
IL (1) | IL149004A0 (en) |
MX (1) | MXPA02003891A (en) |
NZ (1) | NZ518311A (en) |
WO (1) | WO2001028587A2 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9808052D0 (en) | 1998-04-17 | 1998-06-17 | Secr Defence | Implants for administering substances and methods of producing implants |
EP1668424A4 (en) * | 2003-09-12 | 2009-11-25 | Onkor Pharmaceuticals Inc | Magnetically targetable particles comprising magnetic components and biocompatible polymers for site-specific delivery of biologically active agents |
JP2007001865A (en) * | 2003-09-16 | 2007-01-11 | Ltt Bio-Pharma Co Ltd | Fine particle enclosing fat-soluble medicine, method for producing the same and preparation containing the same |
WO2005074991A1 (en) * | 2004-02-09 | 2005-08-18 | Kabushiki Kaisha Sangi | Antitumor agent |
GB0403856D0 (en) * | 2004-02-20 | 2004-03-24 | Algeta As | Composition |
EP1735013B1 (en) * | 2004-02-20 | 2012-02-08 | Algeta ASA | Alpha- and beta-emitting hydroxyapatite particles |
JP2006199810A (en) * | 2005-01-20 | 2006-08-03 | Yokohama National Univ | Composite particle and method for producing the same |
JP5097540B2 (en) * | 2005-04-06 | 2012-12-12 | 株式会社サンギ | Antitumor agent for intestinal absorption |
AU2010246067B2 (en) | 2009-05-04 | 2016-07-07 | Eyepoint Pharmaceuticals Us, Inc. | Porous silicon drug-eluting particles |
AU2011323524B2 (en) * | 2010-11-01 | 2016-12-08 | Eyepoint Pharmaceuticals Us, Inc. | Bioerodible silicon-based devices for delivery of therapeutic agents |
JP6170154B2 (en) * | 2012-08-28 | 2017-07-26 | バイオキューブシステム インコーポレイテッド | Porous solid phase and its use for rapid separation of biological molecules for nucleic acid amplification reactions from biological samples |
AU2014235051B2 (en) | 2013-03-15 | 2019-01-17 | Eyepoint Pharmaceuticals Us, Inc. | Bioerodible silicon-based compositions for delivery of therapeutic agents |
JP6443907B2 (en) * | 2014-02-17 | 2018-12-26 | 浩文 山本 | Accumulation promoter for promoting accumulation of contrast agent in tumor |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4243652A (en) * | 1978-07-14 | 1981-01-06 | The Procter & Gamble Company | Gastrointestinal scanning agent |
ES2066851T3 (en) * | 1988-05-24 | 1995-03-16 | Anagen Uk Ltd | MAGNETICALLY ATTRIBUTABLE PARTICLES AND METHOD OF PREPARATION. |
JP3436760B2 (en) * | 1994-07-27 | 2003-08-18 | ハーバート ピルグリム | Superparamagnetic particles |
WO1997001304A1 (en) * | 1995-06-29 | 1997-01-16 | Mallinckrodt Medical, Inc. | Radiolabeled apatite particles containing a paramagnetic ion |
JP3735990B2 (en) * | 1997-01-28 | 2006-01-18 | 東ソー株式会社 | Method for producing magnetic silica gel |
-
2000
- 2000-10-13 ES ES00972209T patent/ES2182731T1/en active Pending
- 2000-10-13 WO PCT/US2000/028615 patent/WO2001028587A2/en not_active Application Discontinuation
- 2000-10-13 CA CA002387925A patent/CA2387925A1/en not_active Abandoned
- 2000-10-13 IL IL14900400A patent/IL149004A0/en unknown
- 2000-10-13 MX MXPA02003891A patent/MXPA02003891A/en not_active Application Discontinuation
- 2000-10-13 CN CNB008173796A patent/CN1287859C/en not_active Expired - Fee Related
- 2000-10-13 CZ CZ20021357A patent/CZ293919B6/en not_active IP Right Cessation
- 2000-10-13 DE DE1221974T patent/DE1221974T1/en active Pending
- 2000-10-13 JP JP2001531415A patent/JP2003512336A/en active Pending
- 2000-10-13 AU AU10905/01A patent/AU772755B2/en not_active Ceased
- 2000-10-13 NZ NZ518311A patent/NZ518311A/en unknown
- 2000-10-13 EP EP00972209A patent/EP1221974A2/en not_active Withdrawn
- 2000-10-13 KR KR1020027004933A patent/KR20020064299A/en active Search and Examination
- 2000-10-13 BR BR0014877-6A patent/BR0014877A/en not_active IP Right Cessation
-
2002
- 2002-09-05 HK HK02106551.6A patent/HK1045110A1/en unknown
-
2003
- 2003-03-10 JP JP2003063821A patent/JP2003321348A/en not_active Withdrawn
-
2005
- 2005-03-28 JP JP2005093293A patent/JP2005200426A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1221974A2 (en) | 2002-07-17 |
JP2005200426A (en) | 2005-07-28 |
CZ293919B6 (en) | 2004-08-18 |
IL149004A0 (en) | 2002-11-10 |
CA2387925A1 (en) | 2001-04-26 |
CN1287859C (en) | 2006-12-06 |
AU772755B2 (en) | 2004-05-06 |
NZ518311A (en) | 2003-10-31 |
AU1090501A (en) | 2001-04-30 |
JP2003321348A (en) | 2003-11-11 |
KR20020064299A (en) | 2002-08-07 |
MXPA02003891A (en) | 2002-12-09 |
WO2001028587A3 (en) | 2002-01-03 |
CN1420787A (en) | 2003-05-28 |
DE1221974T1 (en) | 2003-02-06 |
WO2001028587A2 (en) | 2001-04-26 |
CZ20021357A3 (en) | 2002-11-13 |
ES2182731T1 (en) | 2003-03-16 |
JP2003512336A (en) | 2003-04-02 |
HK1045110A1 (en) | 2002-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009. |