BR0014801A - Sistemas de processamento de sangue que monitoram densidades óticas - Google Patents
Sistemas de processamento de sangue que monitoram densidades óticasInfo
- Publication number
- BR0014801A BR0014801A BR0014801-6A BR0014801A BR0014801A BR 0014801 A BR0014801 A BR 0014801A BR 0014801 A BR0014801 A BR 0014801A BR 0014801 A BR0014801 A BR 0014801A
- Authority
- BR
- Brazil
- Prior art keywords
- output
- volume
- processing systems
- blood processing
- blood
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
- A61M1/301—Details
- A61M1/302—Details having a reservoir for withdrawn untreated blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
- A61M1/301—Details
- A61M1/303—Details having a reservoir for treated blood to be returned
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
- A61M1/301—Details
- A61M1/305—Control of inversion point between collection and re-infusion phase
- A61M1/308—Volume control, e.g. with open or flexible containers, by counting the number of pump revolutions, weighing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
- B01D17/02—Separation of non-miscible liquids
- B01D17/0217—Separation of non-miscible liquids by centrifugal force
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/0003—Making of sedimentation devices, structural details thereof, e.g. prefabricated parts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/24—Feed or discharge mechanisms for settling tanks
- B01D21/2405—Feed mechanisms for settling tanks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/24—Feed or discharge mechanisms for settling tanks
- B01D21/245—Discharge mechanisms for the sediments
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
- B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/30—Control equipment
- B01D21/32—Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B13/00—Control arrangements specially designed for centrifuges; Programme control of centrifuges
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0427—Platelets; Thrombocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3306—Optical measuring means
- A61M2205/331—Optical measuring means used as turbidity change detectors, e.g. for priming-blood or plasma-hemoglubine-interface detection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/08—Mobile separation devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- External Artificial Organs (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
"SISTEMAS DE PROCESSAMENTO DE SANGUE QUE MONITORAM DENSIDADES óTICAS". Os sistemas e métodos de processamento de sangue separam o sangue em constituintes que incluem um constituinte de plasma que inclui um volume de plaquetas. Os sistemas e métodos detectam a densidade ótica do constituinte de plasma e geram uma primeira saída indicativa da densidade ótica. Um elemento de processamento integra a primeira saída em relação ao volume de constituinte de plasma e gera uma saída integrada. A saída integrada se correlaciona com o volume de plaquetas. Um segundo elemento de processamento (324) gera uma saída com base, pelo menos em parte, na saída integrada, a qual mostra um valor que indica um volume de sangue que precisa ser processado para obter um volume de plaquetas desejado.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/419,727 US6312607B1 (en) | 1995-06-07 | 1999-10-16 | Blood processing systems and methods which optically monitor incremental platelet volumes in a plasma constituent |
PCT/US2000/028178 WO2001028652A1 (en) | 1999-10-16 | 2000-10-12 | Blood processing systems which monitor optical densities |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0014801A true BR0014801A (pt) | 2002-06-11 |
Family
ID=23663500
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0014801-6A BR0014801A (pt) | 1999-10-16 | 2000-10-12 | Sistemas de processamento de sangue que monitoram densidades óticas |
Country Status (11)
Country | Link |
---|---|
US (1) | US6312607B1 (pt) |
EP (1) | EP1229978B1 (pt) |
JP (1) | JP4545364B2 (pt) |
CN (1) | CN1379694A (pt) |
AT (1) | ATE383901T1 (pt) |
AU (1) | AU768997B2 (pt) |
BR (1) | BR0014801A (pt) |
CA (1) | CA2386482A1 (pt) |
DE (1) | DE60037827T2 (pt) |
ES (1) | ES2300277T3 (pt) |
WO (1) | WO2001028652A1 (pt) |
Families Citing this family (43)
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US7186230B2 (en) * | 2002-03-04 | 2007-03-06 | Therakos, Inc | Method and apparatus for the continuous separation of biological fluids into components |
US7211037B2 (en) | 2002-03-04 | 2007-05-01 | Therakos, Inc. | Apparatus for the continuous separation of biological fluids into components and method of using same |
US7479123B2 (en) | 2002-03-04 | 2009-01-20 | Therakos, Inc. | Method for collecting a desired blood component and performing a photopheresis treatment |
ITMI20031715A1 (it) * | 2003-09-05 | 2005-03-06 | Dideco Spa | Dispositivo di comando nella raccolta differenziata dei |
US7060018B2 (en) * | 2003-09-11 | 2006-06-13 | Cobe Cardiovascular, Inc. | Centrifuge apparatus for processing blood |
CN101298008B (zh) * | 2008-01-14 | 2012-10-03 | 经建中 | 应用于混合液体连续离心分离系统上的盘管结构 |
US8075468B2 (en) | 2008-02-27 | 2011-12-13 | Fenwal, Inc. | Systems and methods for mid-processing calculation of blood composition |
US8685258B2 (en) | 2008-02-27 | 2014-04-01 | Fenwal, Inc. | Systems and methods for conveying multiple blood components to a recipient |
CN102027368B (zh) * | 2008-03-21 | 2014-02-26 | 艾博特健康公司 | 利用红细胞内含有的血红蛋白的本征色素沉着来确定血样的红细胞指数的方法及设备 |
US9603989B2 (en) | 2010-08-24 | 2017-03-28 | Fenwal, Inc. | Methods for anticoagulating blood |
DE102011008460A1 (de) | 2011-01-07 | 2012-07-12 | Laser- Und Medizin-Technologie Gmbh, Berlin | Verfahren und Vorrichtung für Bluttransfusion |
US8556793B2 (en) | 2011-02-04 | 2013-10-15 | Fenwal, Inc. | Control of interface between separated blood components under lipemic and hemolytic conditions |
US9164079B2 (en) | 2011-03-17 | 2015-10-20 | Greyledge Technologies Llc | Systems for autologous biological therapeutics |
JP2014518547A (ja) | 2011-04-07 | 2014-07-31 | フェンウォール、インコーポレイテッド | 削減された残存血漿容積を有する血小板濃縮物を提供するための自動化方法とシステムおよびそのような血小板濃縮物のための貯蔵媒体 |
US10413652B2 (en) | 2011-04-13 | 2019-09-17 | Fenwal, Inc. | Systems and methods for use and control of an automated separator with adsorption columns |
WO2012151243A2 (en) | 2011-05-03 | 2012-11-08 | Fenwal, Inc. | Platelet resuspension method and apparatus |
EP2731724B1 (en) * | 2011-09-22 | 2015-01-14 | Fenwal, Inc. | Drive system for centrifuge |
US9334927B2 (en) * | 2011-09-22 | 2016-05-10 | Fenwal, Inc. | Drive system for centrifuge with planetary gear and flexible shaft |
WO2013103446A1 (en) | 2012-01-04 | 2013-07-11 | Fenwal, Inc. | Drive system for centrifuge |
US20140231365A1 (en) * | 2012-07-30 | 2014-08-21 | Fenwal, Inc. | Optical Detection Of Lipids |
EP2892587B1 (en) | 2012-09-04 | 2024-07-03 | Fenwal, Inc. | Interface detector for blood processing system |
US10039877B2 (en) | 2013-08-23 | 2018-08-07 | Fenwal, Inc. | Apheresis platelets with fixed residual plasma volume |
CN104717257B (zh) * | 2013-12-13 | 2018-09-28 | 腾讯科技(深圳)有限公司 | 传输数据报文的方法及装置 |
US9895700B2 (en) | 2014-10-27 | 2018-02-20 | Fenwal, Inc. | Systems and methods for controlling plasma flow rates for therapeutic exchange procedures |
US9872621B2 (en) * | 2014-12-17 | 2018-01-23 | Intel Corporation | Multispectral measurement for improved biological signal acquisition |
US9833557B2 (en) | 2014-12-19 | 2017-12-05 | Fenwal, Inc. | Systems and methods for determining free plasma hemoglobin |
EP3124063B1 (en) | 2015-07-29 | 2019-04-10 | Fenwal, Inc. | Five-port blood separation chamber and methods of using the same |
EP3254713B1 (en) | 2016-06-08 | 2020-01-08 | Fenwal, Inc. | Systems for therapeutic platelet depletion |
EP3372259B1 (en) | 2017-03-07 | 2022-11-23 | Fenwal, Inc. | System and methods for separating blood under conditions of reduced plasma clarity |
JP2020517313A (ja) | 2017-04-20 | 2020-06-18 | フェンウォール、インコーポレイテッド | 添加剤を使用する血小板ろ過のためのシステムおよび方法 |
US10561784B2 (en) | 2017-05-31 | 2020-02-18 | Fenwal, Inc. | Stationary optical monitoring system for blood processing system |
EP3466449B1 (en) | 2017-10-06 | 2022-08-03 | Fenwal, Inc. | Integrated platelet collection and pathogen inactivation processing systems and fluid circuits |
EP3501562A1 (en) | 2017-12-22 | 2019-06-26 | Fenwal, Inc. | Convertible fluid processing assemblies |
EP3553498B1 (en) | 2018-04-13 | 2021-06-02 | Fenwal, Inc. | Optical detection and measurement of hematocrit and free hemoglobin concentration |
US10890524B2 (en) | 2018-06-05 | 2021-01-12 | Fenwal, Inc. | Discerning between the presence of red blood cells and free hemoglobin in a biological fluid |
US11137344B2 (en) | 2018-11-28 | 2021-10-05 | Fenwal, Inc. | Optical mixing of fluids |
US20200196593A1 (en) | 2018-12-21 | 2020-06-25 | Fenwal, Inc. | Methods and Systems for Platelet Cryopreservation |
EP3741460B1 (en) | 2019-05-23 | 2023-09-27 | Fenwal, Inc. | Adjustment of target interface location between separated fluid components in a centrifuge |
EP4000665B1 (en) * | 2019-09-16 | 2023-04-19 | Fenwal, Inc. | Dynamic adjustment of algorithms for separation and collection of blood components |
US11898967B2 (en) | 2021-02-02 | 2024-02-13 | Fenwal, Inc. | Predicting malfunction and failure of centrifuge umbilicus |
CN116422481A (zh) | 2022-01-11 | 2023-07-14 | 汾沃有限公司 | 基于脂质浓度对离心机中的目标界面位置进行调整 |
US20230226562A1 (en) | 2022-01-14 | 2023-07-20 | Fenwal, Inc. | Systems and methods for fluid separation interface control using color-based optical measurements |
WO2024173262A1 (en) | 2023-02-13 | 2024-08-22 | Fenwal, Inc. | Modular biological cell processing system |
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-
1999
- 1999-10-16 US US09/419,727 patent/US6312607B1/en not_active Expired - Lifetime
-
2000
- 2000-10-12 CN CN00814359A patent/CN1379694A/zh active Pending
- 2000-10-12 ES ES00972096T patent/ES2300277T3/es not_active Expired - Lifetime
- 2000-10-12 DE DE60037827T patent/DE60037827T2/de not_active Expired - Lifetime
- 2000-10-12 WO PCT/US2000/028178 patent/WO2001028652A1/en active IP Right Grant
- 2000-10-12 AT AT00972096T patent/ATE383901T1/de active
- 2000-10-12 AU AU10810/01A patent/AU768997B2/en not_active Expired
- 2000-10-12 JP JP2001531479A patent/JP4545364B2/ja not_active Expired - Lifetime
- 2000-10-12 BR BR0014801-6A patent/BR0014801A/pt not_active Application Discontinuation
- 2000-10-12 EP EP00972096A patent/EP1229978B1/en not_active Expired - Lifetime
- 2000-10-12 CA CA002386482A patent/CA2386482A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2003512106A (ja) | 2003-04-02 |
AU768997B2 (en) | 2004-01-15 |
DE60037827D1 (de) | 2008-03-06 |
ES2300277T3 (es) | 2008-06-16 |
EP1229978B1 (en) | 2008-01-16 |
AU1081001A (en) | 2001-04-30 |
DE60037827T2 (de) | 2009-02-05 |
EP1229978A4 (en) | 2005-12-14 |
EP1229978A1 (en) | 2002-08-14 |
US6312607B1 (en) | 2001-11-06 |
WO2001028652A1 (en) | 2001-04-26 |
JP4545364B2 (ja) | 2010-09-15 |
ATE383901T1 (de) | 2008-02-15 |
CA2386482A1 (en) | 2001-04-26 |
CN1379694A (zh) | 2002-11-13 |
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