BR0013153A - Pseudomycin prodrugs - Google Patents

Pseudomycin prodrugs

Info

Publication number
BR0013153A
BR0013153A BR0013153-9A BR0013153A BR0013153A BR 0013153 A BR0013153 A BR 0013153A BR 0013153 A BR0013153 A BR 0013153A BR 0013153 A BR0013153 A BR 0013153A
Authority
BR
Brazil
Prior art keywords
pseudomycin
prodrugs
prodrug
acyloxyalkylcarbamate
pro
Prior art date
Application number
BR0013153-9A
Other languages
Portuguese (pt)
Inventor
Shu Hui Chen
Michael John Rodriguez
Xicheng Sun
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BR0013153A publication Critical patent/BR0013153A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Patente de Invenção: "PRó-DROGAS DE PSEUDOMICINA". é descrita uma pró-droga de pseudomicina representada pela estrutura (A) onde R^ 1^ é uma ligação de aciloxialquilcarbamato. A pró-droga demonstra atividade antifúngica com menos efeitos colaterais adversos.Invention Patent: "PSEUDOMYCIN PRO-DRUGS". there is described a pseudomycin prodrug represented by structure (A) where R3 is an acyloxyalkylcarbamate bond. The prodrug demonstrates antifungal activity with fewer adverse side effects.

BR0013153-9A 1999-07-15 2000-06-08 Pseudomycin prodrugs BR0013153A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14384099P 1999-07-15 1999-07-15
PCT/US2000/015016 WO2001005813A1 (en) 1999-07-15 2000-06-08 Pseudomycin prodrugs

Publications (1)

Publication Number Publication Date
BR0013153A true BR0013153A (en) 2002-04-02

Family

ID=22505903

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0013153-9A BR0013153A (en) 1999-07-15 2000-06-08 Pseudomycin prodrugs

Country Status (11)

Country Link
EP (1) EP1198470A1 (en)
JP (1) JP2003505396A (en)
CN (1) CN1373770A (en)
AU (1) AU5310500A (en)
BR (1) BR0013153A (en)
CA (1) CA2379058A1 (en)
EA (1) EA200200161A1 (en)
HU (1) HUP0202223A3 (en)
MX (1) MXPA02000315A (en)
NO (1) NO20020192L (en)
WO (1) WO2001005813A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
WO2005019163A2 (en) * 2003-08-20 2005-03-03 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
WO2005066122A2 (en) 2003-12-30 2005-07-21 Xenoport, Inc. Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
CN101486668B (en) * 2003-12-30 2014-07-02 什诺波特有限公司 Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
CN101253148B (en) 2005-06-20 2013-01-02 克塞诺波特公司 Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use
US7531572B2 (en) 2006-07-28 2009-05-12 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of α-amino acids, methods of synthesis and use
WO2010017498A1 (en) * 2008-08-07 2010-02-11 Xenoport, Inc. Methods of synthesizing n-hydroxysuccinimidyl carbonates

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5576298A (en) * 1992-11-30 1996-11-19 Research And Development Institute, Inc. At Montana State University Peptides from pseudomonas syringae possessing broad-spectrum antibiotic activity

Also Published As

Publication number Publication date
WO2001005813A1 (en) 2001-01-25
EA200200161A1 (en) 2002-06-27
HUP0202223A2 (en) 2002-10-28
AU5310500A (en) 2001-02-05
HUP0202223A3 (en) 2002-11-28
JP2003505396A (en) 2003-02-12
NO20020192L (en) 2002-03-14
MXPA02000315A (en) 2002-06-21
EP1198470A1 (en) 2002-04-24
CN1373770A (en) 2002-10-09
CA2379058A1 (en) 2001-01-25
NO20020192D0 (en) 2002-01-14

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]