BR0009666A - Recombinant and mutant adenoviruses derived from bovine type 1 adenoviruses - Google Patents

Recombinant and mutant adenoviruses derived from bovine type 1 adenoviruses

Info

Publication number
BR0009666A
BR0009666A BR0009666-0A BR0009666A BR0009666A BR 0009666 A BR0009666 A BR 0009666A BR 0009666 A BR0009666 A BR 0009666A BR 0009666 A BR0009666 A BR 0009666A
Authority
BR
Brazil
Prior art keywords
adenoviruses
mutant
recombinant
present
derived
Prior art date
Application number
BR0009666-0A
Other languages
Portuguese (pt)
Inventor
Christina H Chiang
Mark D Cochran
Original Assignee
Schering Plough Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Plough Ltd filed Critical Schering Plough Ltd
Publication of BR0009666A publication Critical patent/BR0009666A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Patente de Invenção: "ADENOVìRUS RECOMBINANTE E MUTANTE DERIVADO DE ADENOVìRUS BOVINO TIPO 1". A presente invenção provê vetores virais. Em uma modalidade, a presente invenção provê adenovírus bovinos mutantes e recombinantes tendo uma deleção e/ou inserção de DNA na região de gene inicial 4 (E4). Em uma outra modalidade, a presente invenção provê um vírus adenovírus bovino 1 mutante e recombinante tendo uma deleção e/ou inserção de DNA na região de gene inicial 3 (E3). A presente invenção também contempla o uso dos vetores virais para vacinação, terapia genética ou outras aplicações como apropriado.Invention Patent: "RECOMBINANT ADENOVIRUS AND MUTANT DERIVED FROM BOVINE ADENOVIRUS TYPE 1". The present invention provides viral vectors. In one embodiment, the present invention provides mutant and recombinant bovine adenoviruses having a DNA deletion and / or insertion in the initial gene region 4 (E4). In another embodiment, the present invention provides a mutant and recombinant bovine adenovirus 1 virus having a DNA deletion and / or insertion in the initial gene region 3 (E3). The present invention also contemplates the use of viral vectors for vaccination, gene therapy or other applications as appropriate.

BR0009666-0A 1999-04-09 2000-04-07 Recombinant and mutant adenoviruses derived from bovine type 1 adenoviruses BR0009666A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28993099A 1999-04-09 1999-04-09
PCT/US2000/009459 WO2000061773A1 (en) 1999-04-09 2000-04-07 Recombinant and mutant adenoviruses derived of bovine adenovirus type 1

Publications (1)

Publication Number Publication Date
BR0009666A true BR0009666A (en) 2002-02-05

Family

ID=23113786

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0009666-0A BR0009666A (en) 1999-04-09 2000-04-07 Recombinant and mutant adenoviruses derived from bovine type 1 adenoviruses

Country Status (7)

Country Link
EP (1) EP1169464A1 (en)
JP (1) JP2002541815A (en)
AU (1) AU4220600A (en)
BR (1) BR0009666A (en)
CA (1) CA2365911A1 (en)
MX (1) MXPA01010148A (en)
WO (1) WO2000061773A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7906311B2 (en) 2002-03-20 2011-03-15 Merial Limited Cotton rat lung cells for virus culture
AU2003239589A1 (en) 2002-05-24 2003-12-12 Schering-Plough Ltd. Eta-1 gene and methods for use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5820868A (en) * 1993-12-09 1998-10-13 Veterinary Infectious Disease Organization Recombinant protein production in bovine adenovirus expression vector system
FR2725726B1 (en) * 1994-10-17 1997-01-03 Centre Nat Rech Scient VIRAL VECTORS AND USE IN GENE THERAPY
JP2002512501A (en) * 1996-07-03 2002-04-23 メリアル インコーポレイテッド Recombinant canine adenovirus (CAV) containing exogenous DNA

Also Published As

Publication number Publication date
MXPA01010148A (en) 2003-07-14
CA2365911A1 (en) 2000-10-19
AU4220600A (en) 2000-11-14
WO2000061773A1 (en) 2000-10-19
JP2002541815A (en) 2002-12-10
EP1169464A1 (en) 2002-01-09

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired