BR0008065A - Unsaturated cholestane derivatives and their use for the preparation of medicines that regulate meiosis - Google Patents

Unsaturated cholestane derivatives and their use for the preparation of medicines that regulate meiosis

Info

Publication number
BR0008065A
BR0008065A BR0008065-9A BR0008065A BR0008065A BR 0008065 A BR0008065 A BR 0008065A BR 0008065 A BR0008065 A BR 0008065A BR 0008065 A BR0008065 A BR 0008065A
Authority
BR
Brazil
Prior art keywords
preparation
medicines
cholestane derivatives
regulate
unsaturated
Prior art date
Application number
BR0008065-9A
Other languages
Portuguese (pt)
Inventor
Thorsten Blume
Peter Esperling
Joachim Kuhnke
Christa Hegele-Hartung
Monika Lessl
Original Assignee
Schering Aktiengellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengellschaft filed Critical Schering Aktiengellschaft
Publication of BR0008065A publication Critical patent/BR0008065A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: "DERIVADOS DE COLESTANO INSATURADOS E SEU USO PARA A PREPARAçãO DE MEDICAMENTOS QUE REGULAM MEIOSE". A presente invenção refere-se a derivados de colestano insaturados farmaceuticamente ativos, a composições farmacêuticas que os compreendem como substâncias ativas e ao uso destes novos compostos para a preparação de medicamentos. Mais particularmente, verificou-se que os derivados de colestano insaturados da invenção podem ser usados para regular meiose.Invention Patent: "Unsaturated cholestane derivatives and their use for the preparation of medications that regulate myosis". The present invention relates to pharmaceutically active unsaturated cholestane derivatives, to pharmaceutical compositions that comprise them as active substances and to the use of these new compounds for the preparation of medicaments. More particularly, it has been found that the unsaturated cholestane derivatives of the invention can be used to regulate meiosis.

BR0008065-9A 1999-02-10 2000-02-09 Unsaturated cholestane derivatives and their use for the preparation of medicines that regulate meiosis BR0008065A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99250040 1999-02-10
PCT/EP2000/001074 WO2000047604A1 (en) 1999-02-10 2000-02-09 Unsaturated cholestane derivatives and their use for the preparation of meiosis regulating medicaments

Publications (1)

Publication Number Publication Date
BR0008065A true BR0008065A (en) 2001-11-06

Family

ID=8241140

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008065-9A BR0008065A (en) 1999-02-10 2000-02-09 Unsaturated cholestane derivatives and their use for the preparation of medicines that regulate meiosis

Country Status (15)

Country Link
EP (1) EP1150993A1 (en)
JP (1) JP2002536456A (en)
KR (1) KR20010101820A (en)
CN (1) CN1368977A (en)
AU (1) AU3279700A (en)
BR (1) BR0008065A (en)
CA (1) CA2359687A1 (en)
CZ (1) CZ20012866A3 (en)
HU (1) HUP0200280A2 (en)
IL (1) IL143735A0 (en)
NO (1) NO20013901D0 (en)
PL (1) PL350557A1 (en)
SK (1) SK11382001A3 (en)
WO (1) WO2000047604A1 (en)
ZA (1) ZA200107387B (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols
JPH11501806A (en) * 1995-03-06 1999-02-16 ノボ ノルディスク アクティーゼルスカブ Stimulation of meiosis
EP0857173B1 (en) * 1995-06-23 2003-11-19 Novo Nordisk A/S Meiosis regulating compounds
KR20000069616A (en) * 1996-12-20 2000-11-25 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 Meiosis regulating compounds

Also Published As

Publication number Publication date
IL143735A0 (en) 2002-04-21
NO20013901L (en) 2001-08-10
SK11382001A3 (en) 2002-01-07
NO20013901D0 (en) 2001-08-10
AU3279700A (en) 2000-08-29
CZ20012866A3 (en) 2002-01-16
CA2359687A1 (en) 2000-08-17
PL350557A1 (en) 2002-12-16
ZA200107387B (en) 2002-12-06
CN1368977A (en) 2002-09-11
WO2000047604A1 (en) 2000-08-17
JP2002536456A (en) 2002-10-29
EP1150993A1 (en) 2001-11-07
KR20010101820A (en) 2001-11-14
HUP0200280A2 (en) 2002-07-29

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]