BG62084B1 - Ултразвуково контрастно средство - Google Patents

Ултразвуково контрастно средство Download PDF

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Publication number
BG62084B1
BG62084B1 BG99998A BG9999895A BG62084B1 BG 62084 B1 BG62084 B1 BG 62084B1 BG 99998 A BG99998 A BG 99998A BG 9999895 A BG9999895 A BG 9999895A BG 62084 B1 BG62084 B1 BG 62084B1
Authority
BG
Bulgaria
Prior art keywords
gas
contrast agent
agent according
oil
fluid
Prior art date
Application number
BG99998A
Other languages
Bulgarian (bg)
English (en)
Inventor
Arne Berg
Harald Dugstad
Per A. Foss
Jo Klaveness
Jonny Ostensen
Pal Rongved
Per Strande
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of BG62084B1 publication Critical patent/BG62084B1/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/226Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Coating Apparatus (AREA)
BG99998A 1993-03-16 1995-09-12 Ултразвуково контрастно средство BG62084B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939305349A GB9305349D0 (en) 1993-03-16 1993-03-16 Improvements in or relating to contrast agents
PCT/GB1994/000521 WO1994021301A1 (en) 1993-03-16 1994-03-16 Improvements in or relating to contrast agents

Publications (1)

Publication Number Publication Date
BG62084B1 true BG62084B1 (bg) 1999-02-26

Family

ID=10732116

Family Applications (2)

Application Number Title Priority Date Filing Date
BG99998A BG62084B1 (bg) 1993-03-16 1995-09-12 Ултразвуково контрастно средство
BG100272A BG100272A (en) 1993-03-16 1995-09-12 Contrast compositions

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG100272A BG100272A (en) 1993-03-16 1995-09-12 Contrast compositions

Country Status (21)

Country Link
EP (1) EP0689461B1 (pt)
JP (1) JP3787639B2 (pt)
KR (1) KR960700759A (pt)
CN (1) CN1066963C (pt)
AT (1) ATE194292T1 (pt)
AU (1) AU696091B2 (pt)
BG (2) BG62084B1 (pt)
BR (1) BR9406228A (pt)
CA (1) CA2158365A1 (pt)
CZ (1) CZ237095A3 (pt)
DE (1) DE69425136T2 (pt)
ES (1) ES2147784T3 (pt)
FI (1) FI954325A (pt)
GB (1) GB9305349D0 (pt)
HK (1) HK1004981A1 (pt)
HU (1) HUT72982A (pt)
NO (1) NO953637D0 (pt)
PL (1) PL175128B1 (pt)
RU (1) RU2128520C1 (pt)
SK (1) SK113895A3 (pt)
WO (1) WO1994021301A1 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874062A (en) * 1991-04-05 1999-02-23 Imarx Pharmaceutical Corp. Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents
US5409688A (en) * 1991-09-17 1995-04-25 Sonus Pharmaceuticals, Inc. Gaseous ultrasound contrast media
WO1994009703A1 (en) * 1992-11-02 1994-05-11 Drexel University Surfactant-stabilized microbubble mixtures, process for preparing and methods of using the same
US5716597A (en) * 1993-06-04 1998-02-10 Molecular Biosystems, Inc. Emulsions as contrast agents and method of use
US5736121A (en) * 1994-05-23 1998-04-07 Imarx Pharmaceutical Corp. Stabilized homogenous suspensions as computed tomography contrast agents
US5804162A (en) * 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
US5897851A (en) * 1995-06-07 1999-04-27 Sonus Pharmaceuticals, Inc. Nucleation and activation of a liquid-in-liquid emulsion for use in ultrasound imaging
US5834519A (en) * 1996-10-11 1998-11-10 Wayne State University Stabilized gas-supersaturated emulsions and suspensions
US6548047B1 (en) * 1997-09-15 2003-04-15 Bristol-Myers Squibb Medical Imaging, Inc. Thermal preactivation of gaseous precursor filled compositions
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
GB9808581D0 (en) * 1998-04-22 1998-06-24 Nycomed Imaging As Improvements in or relating to contrast agents
US6514209B1 (en) 1999-06-07 2003-02-04 Drexel University Method of enhancing ultrasonic techniques via measurement of ultraharmonic signals
WO2002034297A2 (en) * 2000-10-24 2002-05-02 Visys Ag Endoscopic vascular visualisation, diagnostic and/or surgical procedure
US8323620B2 (en) * 2004-10-22 2012-12-04 Hitachi Medical Corporation Ultrasound contrast agent
WO2007137236A2 (en) 2006-05-19 2007-11-29 Drexel University Drug loaded contrast agents: combining diagnosis and therapy
JP4800862B2 (ja) * 2006-06-21 2011-10-26 株式会社日立製作所 ファントム
JP5124185B2 (ja) * 2007-07-02 2013-01-23 株式会社日立製作所 診断又は治療用薬剤の調製方法及び装置
US9770521B2 (en) 2012-05-09 2017-09-26 Sinvent As Ultrasound contact fluid
NZ733010A (en) 2014-12-31 2023-01-27 Lantheus Medical Imaging Inc Lipid-encapsulated gas microsphere compositions and related methods
IL262647B2 (en) 2016-05-04 2023-03-01 Lantheus Medical Imaging Inc Methods and devices for preparing sharpness factors for ultrasound
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900540A (en) * 1983-06-20 1990-02-13 Trustees Of The University Of Massachusetts Lipisomes containing gas for ultrasound detection
US4684479A (en) * 1985-08-14 1987-08-04 Arrigo Joseph S D Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures
EP0245019A3 (en) * 1986-04-30 1989-05-10 Michael A. Davis Low density contrast medium for diagnosis of pathologic conditions
DE58908194D1 (de) * 1988-02-05 1994-09-22 Schering Ag Ultraschallkontrastmittel, verfahren zu deren herstellung und deren verwendung als diagnostika und therapeutika.
US5088499A (en) * 1989-12-22 1992-02-18 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
WO1993005819A1 (en) * 1991-09-17 1993-04-01 Sonus Pharmaceuticals, Inc Gaseous ultrasound contrast media and method for selecting gases for use as ultrasound contrast media
IL104084A (en) * 1992-01-24 1996-09-12 Bracco Int Bv Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them

Also Published As

Publication number Publication date
FI954325A (fi) 1995-10-11
JPH08509706A (ja) 1996-10-15
ES2147784T3 (es) 2000-10-01
BR9406228A (pt) 1995-12-12
GB9305349D0 (en) 1993-05-05
AU696091B2 (en) 1998-09-03
ATE194292T1 (de) 2000-07-15
CZ237095A3 (en) 1996-03-13
KR960700759A (ko) 1996-02-24
PL175128B1 (pl) 1998-11-30
SK113895A3 (en) 1997-02-05
WO1994021301A1 (en) 1994-09-29
DE69425136T2 (de) 2001-03-22
DE69425136D1 (de) 2000-08-10
CN1121315A (zh) 1996-04-24
HK1004981A1 (en) 1998-12-18
CA2158365A1 (en) 1994-09-29
BG100272A (en) 1996-05-31
EP0689461A1 (en) 1996-01-03
PL310656A1 (en) 1995-12-27
FI954325A0 (fi) 1995-09-14
HU9502694D0 (en) 1995-11-28
AU6215294A (en) 1994-10-11
HUT72982A (en) 1996-06-28
RU2128520C1 (ru) 1999-04-10
CN1066963C (zh) 2001-06-13
NO953637L (no) 1995-09-15
EP0689461B1 (en) 2000-07-05
NO953637D0 (no) 1995-09-15
JP3787639B2 (ja) 2006-06-21

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