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Application filed by T Kom Za Promishlena MikrobiolfiledCriticalT Kom Za Promishlena Mikrobiol
Priority to BG8560588ApriorityCriticalpatent/BG50559A1/en
Publication of BG50559A1publicationCriticalpatent/BG50559A1/en
Synthesized cephalosporin antibiotics are used in medicine for therapy. By this method, compounds with high output are derived directly from outgoing β-lactamic substrates, which are acylated in the amino group, in a water environment, with the help of a biocatalyst with acylate enzyme activity produced from E.coli, preferably under temperatures between 25 and 40 degrees C, and a pH between 5.0 and 7.0.
BG8560588A1988-10-051988-10-05Method for the preparation of cephalosporine compounds
BG50559A1
(en)
System for excretion of foreign protein,enzymes or polypeptides from e. coli into the culture media,especially for the production and purification of the enzyme chitinase