WO1991010721A3 - Process for high cell density fermentation of escherichia coli in an agitated boiler fermenter - Google Patents

Process for high cell density fermentation of escherichia coli in an agitated boiler fermenter Download PDF

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Publication number
WO1991010721A3
WO1991010721A3 PCT/EP1990/002301 EP9002301W WO9110721A3 WO 1991010721 A3 WO1991010721 A3 WO 1991010721A3 EP 9002301 W EP9002301 W EP 9002301W WO 9110721 A3 WO9110721 A3 WO 9110721A3
Authority
WO
WIPO (PCT)
Prior art keywords
fermenter
escherichia coli
cell density
high cell
density fermentation
Prior art date
Application number
PCT/EP1990/002301
Other languages
German (de)
French (fr)
Other versions
WO1991010721A2 (en
Inventor
Wolf-Dieter Deckwer
Wofgang Knorre
Dieter Korz
Hans Dieter Pohl
Dieter Riesenberg
Anton Ross
Ernst Sanders
Volker Schulz
Original Assignee
Biotechnolog Forschung Gmbh
Zimet Zentralinstitut Fuer Mik
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6398409&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO1991010721(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biotechnolog Forschung Gmbh, Zimet Zentralinstitut Fuer Mik filed Critical Biotechnolog Forschung Gmbh
Priority to DE59008683T priority Critical patent/DE59008683D1/en
Priority to EP91901288A priority patent/EP0511226B1/en
Priority to BR909007980A priority patent/BR9007980A/en
Publication of WO1991010721A2 publication Critical patent/WO1991010721A2/en
Publication of WO1991010721A3 publication Critical patent/WO1991010721A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor

Abstract

The invention relates to a process for high cell density fermentation of Escherichia coli in an agitated boiler fermenter.
PCT/EP1990/002301 1990-01-19 1990-12-24 Process for high cell density fermentation of escherichia coli in an agitated boiler fermenter WO1991010721A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE59008683T DE59008683D1 (en) 1990-01-19 1990-12-24 METHOD FOR THE HIGH CELL DENSITY FERMENTATION OF ESCHERICHIA COLI IN A STIRRANT BOILER FERMENTOR.
EP91901288A EP0511226B1 (en) 1990-01-19 1990-12-24 Process for high cell density fermentation of escherichia coli in an agitated boiler fermenter
BR909007980A BR9007980A (en) 1990-01-19 1990-12-24 PROCESS FOR FERMENTATION WITH HIGH CELL DENSITY OF ESCHERICHIA COLI IN AN AGITATED TANK FERMENTER

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4001518A DE4001518A1 (en) 1990-01-19 1990-01-19 METHOD FOR THE HIGH CELL DENSITY FERMENTATION OF ESCHERICHIA COLI IN A STIRRED BOTTOM FERMENTOR
DEP4001518.1 1990-01-19

Publications (2)

Publication Number Publication Date
WO1991010721A2 WO1991010721A2 (en) 1991-07-25
WO1991010721A3 true WO1991010721A3 (en) 1991-09-19

Family

ID=6398409

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1990/002301 WO1991010721A2 (en) 1990-01-19 1990-12-24 Process for high cell density fermentation of escherichia coli in an agitated boiler fermenter

Country Status (9)

Country Link
EP (1) EP0511226B1 (en)
AT (1) ATE119570T1 (en)
BR (1) BR9007980A (en)
CA (1) CA2073974A1 (en)
CS (1) CS11791A2 (en)
DE (2) DE4001518A1 (en)
DK (1) DK0511226T3 (en)
HU (1) HUT65613A (en)
WO (1) WO1991010721A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981735A (en) * 1996-02-12 1999-11-09 Cobra Therapeutics Limited Method of plasmid DNA production and purification
GB9602825D0 (en) * 1996-02-12 1996-04-10 Therexsys Ltd Method of plasmid dna production and purification
MX339227B (en) 2010-08-30 2016-05-17 Hoffmann La Roche Alkaline feed.
KR102036671B1 (en) 2012-03-12 2019-11-26 한미사이언스 주식회사 Method of culturing E. coli for high density
EP3927837A1 (en) 2019-02-20 2021-12-29 Basf Se Industrial fermentation process for bacillus using defined medium and magnesium feed
WO2020169564A1 (en) 2019-02-20 2020-08-27 Basf Se Industrial fermentation process for bacillus using defined medium and trace element feed
CN115786214B (en) * 2022-12-26 2023-08-18 湖北擎科生物科技有限公司 High-density fermentation culture medium and high-density fermentation culture method for competent escherichia coli

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2601254A1 (en) * 1976-01-15 1977-07-21 Braun Melsungen Ag Partial gas pressure control in fermenters - by varying gas throughput and stirrer speed
DE2714708A1 (en) * 1976-04-02 1977-10-13 Ici Ltd METHOD OF GROWING CELLS
EP0065895A1 (en) * 1981-05-08 1982-12-01 L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Method for producing microorganisms
EP0315944A2 (en) * 1987-11-09 1989-05-17 Genencor International, Inc. Controlled growth rate fermentation
EP0345588A1 (en) * 1988-06-03 1989-12-13 Gesellschaft für Biotechnologische Forschung mbH (GBF) Method and device for monitoring a biological growth process

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2601254A1 (en) * 1976-01-15 1977-07-21 Braun Melsungen Ag Partial gas pressure control in fermenters - by varying gas throughput and stirrer speed
DE2714708A1 (en) * 1976-04-02 1977-10-13 Ici Ltd METHOD OF GROWING CELLS
EP0065895A1 (en) * 1981-05-08 1982-12-01 L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Method for producing microorganisms
EP0315944A2 (en) * 1987-11-09 1989-05-17 Genencor International, Inc. Controlled growth rate fermentation
EP0345588A1 (en) * 1988-06-03 1989-12-13 Gesellschaft für Biotechnologische Forschung mbH (GBF) Method and device for monitoring a biological growth process

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Biotechnology, Band 7, November 1989, (New York, US), L. Eppstein et al.: "Increased biomass production in a benchtop fermentor", Seiten 1178-1181 *
FSTA Journal 91-08 B 0215, D. Riesenberg et al.: "High cell density fermentation of recombinant escherichia coli expressing human interferon alpha 1", *

Also Published As

Publication number Publication date
CA2073974A1 (en) 1991-07-20
DE4001518A1 (en) 1991-07-25
BR9007980A (en) 1992-11-17
EP0511226A1 (en) 1992-11-04
EP0511226B1 (en) 1995-03-08
HUT65613A (en) 1994-07-28
ATE119570T1 (en) 1995-03-15
CS11791A2 (en) 1991-08-13
HU9202332D0 (en) 1993-05-28
DE59008683D1 (en) 1995-04-13
DE4001518C2 (en) 1992-01-30
WO1991010721A2 (en) 1991-07-25
DK0511226T3 (en) 1995-04-10

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