BG34181A3 - Метод за получаване на антигенен препарат - Google Patents
Метод за получаване на антигенен препаратInfo
- Publication number
- BG34181A3 BG34181A3 BG034303A BG3430376A BG34181A3 BG 34181 A3 BG34181 A3 BG 34181A3 BG 034303 A BG034303 A BG 034303A BG 3430376 A BG3430376 A BG 3430376A BG 34181 A3 BG34181 A3 BG 34181A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- antigenic protein
- antigene
- obtaining
- patent medicine
- microvesicles
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 230000000890 antigenic effect Effects 0.000 abstract 6
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 239000000232 Lipid Bilayer Substances 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 2
- 239000002502 liposome Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Метод за получаване на антигенен препарат, съдържащ липозоми и антигенен протеин, характеризиращ се с това, че липидът, от който са съставени липозомите се разклаща във водна среда до образуване на микровезикули, които след това се разклащат в присъствие на антигенен протеин, при което антигенният протеин се свързва с външната повърхност на липидния двоен слой на микровезикулите, като в даден случай за свързване на антигенния протеин с външната повърхност на липидния двоен слой на микровезикулите се разклаща смес от липид, водна среда и антигенен протеин. Автентните претенции са формулирани в 5 точки.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB39857/75A GB1564500A (en) | 1975-09-29 | 1975-09-29 | Biological preparations |
Publications (1)
Publication Number | Publication Date |
---|---|
BG34181A3 true BG34181A3 (bg) | 1983-07-15 |
Family
ID=10411873
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG034303A BG34181A3 (bg) | 1975-09-29 | 1976-09-28 | Метод за получаване на антигенен препарат |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS5244228A (bg) |
AU (1) | AU514848B2 (bg) |
BE (1) | BE846681A (bg) |
BG (1) | BG34181A3 (bg) |
CA (1) | CA1079634A (bg) |
DD (1) | DD127598A5 (bg) |
DE (1) | DE2643641A1 (bg) |
ES (1) | ES451923A1 (bg) |
FR (1) | FR2325387A1 (bg) |
GB (1) | GB1564500A (bg) |
HU (1) | HU176180B (bg) |
NL (1) | NL7610736A (bg) |
PL (1) | PL103082B1 (bg) |
SE (1) | SE7610708L (bg) |
ZA (1) | ZA765817B (bg) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4148876A (en) | 1975-09-29 | 1979-04-10 | Burroughs Wellcome Co. | Biological preparations |
US4196191A (en) | 1975-09-29 | 1980-04-01 | Burroughs Wellcome Co. | Biological preparations |
FR2442241A2 (fr) * | 1978-03-20 | 1980-06-20 | Anvar | Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes |
FR2420545A1 (fr) * | 1978-03-20 | 1979-10-19 | Anvar | Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques |
GB2026340B (en) * | 1978-07-03 | 1982-12-22 | Ash P | Stabilising microvesicles |
US4201767A (en) * | 1978-11-08 | 1980-05-06 | Merck & Co., Inc. | Viral liposome particle |
US4199565A (en) * | 1979-03-26 | 1980-04-22 | Merck & Co., Inc. | Liposome particle containing viral or bacterial antigenic subunit |
HU184141B (en) * | 1979-12-27 | 1984-07-30 | Human Oltoanyagtermelo | Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof |
DE3173713D1 (en) * | 1980-09-05 | 1986-03-20 | Frappier Armand Inst | Formation of an immunosome exclusively made of viral antigens reconstituted on an artificial membrane |
FR2543018B1 (fr) * | 1983-03-22 | 1985-07-26 | Oreal | Procede de preparation de vesicules lipidiques par vaporisation de solvants |
IT1238343B (it) * | 1989-10-16 | 1993-07-13 | Cesalpino Andrea Fond | Procedimento per la preparazione di vaccini capaci di generare non solo la risposta immune dei linfociti t helper,ma anche un'efficace risposta di linfociti t citotossici,e vaccini con queste caratteristiche |
CA2131442A1 (en) * | 1992-03-03 | 1993-09-04 | Seishi Tsuchiya | Oral vaccine |
US6096291A (en) * | 1996-12-27 | 2000-08-01 | Biovector Therapeutics, S.A. | Mucosal administration of substances to mammals |
CN105899220B (zh) * | 2013-12-19 | 2020-01-10 | 扬森疫苗与预防公司 | 改进的病毒体配制品 |
-
1975
- 1975-09-29 GB GB39857/75A patent/GB1564500A/en not_active Expired
-
1976
- 1976-09-28 ES ES451923A patent/ES451923A1/es not_active Expired
- 1976-09-28 DD DD7600195018A patent/DD127598A5/xx unknown
- 1976-09-28 JP JP51116473A patent/JPS5244228A/ja active Pending
- 1976-09-28 ZA ZA00765817A patent/ZA765817B/xx unknown
- 1976-09-28 DE DE19762643641 patent/DE2643641A1/de not_active Withdrawn
- 1976-09-28 AU AU18164/76A patent/AU514848B2/en not_active Expired
- 1976-09-28 HU HU76WE542A patent/HU176180B/hu unknown
- 1976-09-28 NL NL7610736A patent/NL7610736A/xx not_active Application Discontinuation
- 1976-09-28 PL PL1976192701A patent/PL103082B1/pl unknown
- 1976-09-28 CA CA262,165A patent/CA1079634A/en not_active Expired
- 1976-09-28 BG BG034303A patent/BG34181A3/bg unknown
- 1976-09-28 BE BE171023A patent/BE846681A/xx not_active IP Right Cessation
- 1976-09-28 SE SE7610708A patent/SE7610708L/ not_active Application Discontinuation
- 1976-09-28 FR FR7629064A patent/FR2325387A1/fr active Granted
Also Published As
Publication number | Publication date |
---|---|
ZA765817B (en) | 1978-05-30 |
DE2643641A1 (de) | 1977-04-14 |
NL7610736A (nl) | 1977-03-31 |
GB1564500A (en) | 1980-04-10 |
AU514848B2 (en) | 1981-03-05 |
HU176180B (en) | 1980-12-28 |
ES451923A1 (es) | 1977-08-16 |
DD127598A5 (de) | 1977-10-05 |
SE7610708L (sv) | 1977-03-30 |
CA1079634A (en) | 1980-06-17 |
PL103082B1 (pl) | 1979-05-31 |
BE846681A (fr) | 1977-03-28 |
FR2325387A1 (fr) | 1977-04-22 |
AU1816476A (en) | 1978-04-06 |
JPS5244228A (en) | 1977-04-07 |
FR2325387B1 (bg) | 1980-06-27 |
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