BG20609A3 - Метод за получаване на 7-алфа-хидрокси-алфа-фенил(ацетамидо-3/1- метил-1н-тетразол-5-илтиометил)-3-цефем-4-карбонова киселина - Google Patents

Метод за получаване на 7-алфа-хидрокси-алфа-фенил(ацетамидо-3/1- метил-1н-тетразол-5-илтиометил)-3-цефем-4-карбонова киселина

Info

Publication number
BG20609A3
BG20609A3 BG023051A BG2305173A BG20609A3 BG 20609 A3 BG20609 A3 BG 20609A3 BG 023051 A BG023051 A BG 023051A BG 2305173 A BG2305173 A BG 2305173A BG 20609 A3 BG20609 A3 BG 20609A3
Authority
BG
Bulgaria
Prior art keywords
alpha
ylthiomethyl
cephem
acetamido
tetrazole
Prior art date
Application number
BG023051A
Other languages
Bulgarian (bg)
English (en)
Inventor
Tames Greeve
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of BG20609A3 publication Critical patent/BG20609A3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D317/34Oxygen atoms
    • C07D317/36Alkylene carbonates; Substituted alkylene carbonates
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG023051A 1972-03-21 1973-03-21 Метод за получаване на 7-алфа-хидрокси-алфа-фенил(ацетамидо-3/1- метил-1н-тетразол-5-илтиометил)-3-цефем-4-карбонова киселина BG20609A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00236764A US3840531A (en) 1972-03-21 1972-03-21 Process for preparing 7-(alpha-hydroxy-alpha-phenyl)acetamido-3-(1-methyl-1h-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and derivatives thereof

Publications (1)

Publication Number Publication Date
BG20609A3 true BG20609A3 (bg) 1975-12-05

Family

ID=22890856

Family Applications (1)

Application Number Title Priority Date Filing Date
BG023051A BG20609A3 (bg) 1972-03-21 1973-03-21 Метод за получаване на 7-алфа-хидрокси-алфа-фенил(ацетамидо-3/1- метил-1н-тетразол-5-илтиометил)-3-цефем-4-карбонова киселина

Country Status (28)

Country Link
US (1) US3840531A (de)
JP (1) JPS5541237B2 (de)
AR (1) AR193934A1 (de)
AT (1) AT330347B (de)
AU (1) AU465689B2 (de)
BE (1) BE796788A (de)
BG (1) BG20609A3 (de)
BR (1) BR7301970D0 (de)
CA (1) CA994327A (de)
CH (1) CH557382A (de)
CS (1) CS182782B2 (de)
DD (1) DD105240A5 (de)
DE (1) DE2312997A1 (de)
DK (1) DK143854C (de)
ES (1) ES412859A1 (de)
FR (1) FR2182884B1 (de)
GB (1) GB1400697A (de)
HU (1) HU165339B (de)
IE (1) IE37402B1 (de)
IL (1) IL41711A (de)
NL (1) NL7303917A (de)
PH (1) PH9650A (de)
PL (1) PL85244B1 (de)
RO (1) RO62621A (de)
SE (1) SE416473B (de)
SU (1) SU632295A3 (de)
YU (1) YU35601B (de)
ZA (1) ZA731644B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1449420A (en) * 1973-11-26 1976-09-15 Sankyo Co 7alpha-methoxycephalosporing derivatives
DE2512284A1 (de) * 1974-03-28 1975-10-09 Fujisawa Pharmaceutical Co Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
US3933808A (en) * 1974-05-20 1976-01-20 Eli Lilly And Company Cephalosporin esters
US3928334A (en) * 1974-06-06 1975-12-23 Bristol Myers Co Process for the production of cefamandole
US3928337A (en) * 1974-08-07 1975-12-23 Bristol Myers Co Process for the production of cefamandole
US3947415A (en) * 1974-12-23 1976-03-30 Eli Lilly And Company Cefamandole derivatives
US3947414A (en) * 1974-12-23 1976-03-30 Eli Lilly And Company Cefamandole derivatives
US4035361A (en) * 1976-03-17 1977-07-12 Eli Lilly And Company Bis-trimethylsilyl cefamandole and process therefor
GB1565941A (en) * 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
US4115644A (en) * 1977-09-19 1978-09-19 Eli Lilly And Company Process for preparing pure cefamandole from alkali metal and ammonium salts thereof
JPS6027677B2 (ja) * 1978-07-06 1985-06-29 富山化学工業株式会社 7−置換又は非置換アミノ−3−置換チオメチルセフエムカルボン酸類の新規製造法
JPS5543043A (en) * 1978-09-22 1980-03-26 Sankyo Co Ltd Preparation of 3-substituted thiomethylcephalosporin derivative
US4351947A (en) * 1980-03-06 1982-09-28 Asahi Chemical Industry Co., Ltd. Tetrazole derivative

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3167549A (en) * 1961-05-18 1965-01-26 Smith Kline French Lab Derivatives of 7-aminocephalosporanic acid

Also Published As

Publication number Publication date
CA994327A (en) 1976-08-03
IL41711A (en) 1976-03-31
AU465689B2 (en) 1975-10-02
HU165339B (de) 1974-08-28
PL85244B1 (de) 1976-04-30
JPS5541237B2 (de) 1980-10-22
YU71073A (en) 1980-10-31
US3840531A (en) 1974-10-08
FR2182884A1 (de) 1973-12-14
SU632295A3 (ru) 1978-11-05
CS182782B2 (en) 1978-05-31
FR2182884B1 (de) 1977-01-28
RO62621A (fr) 1978-05-15
ZA731644B (en) 1974-10-30
DK143854C (da) 1982-04-05
BE796788A (fr) 1973-09-17
JPS495987A (de) 1974-01-19
GB1400697A (en) 1975-07-23
ATA246073A (de) 1975-09-15
SE416473B (sv) 1981-01-05
ES412859A1 (es) 1976-06-01
IE37402B1 (en) 1977-07-20
AT330347B (de) 1976-06-25
AU5306073A (en) 1974-09-12
IL41711A0 (en) 1973-05-31
DE2312997A1 (de) 1973-11-15
BR7301970D0 (pt) 1974-08-29
DD105240A5 (de) 1974-04-12
NL7303917A (de) 1973-09-25
CH557382A (fr) 1974-12-31
DK143854B (da) 1981-10-19
YU35601B (en) 1981-04-30
PH9650A (en) 1976-01-27
IE37402L (en) 1973-09-21
AR193934A1 (es) 1973-05-31

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