BG103937A - 5-naphthalen-1-yl-1,3-dioxane derivatives, their preparation and application in therapy - Google Patents
5-naphthalen-1-yl-1,3-dioxane derivatives, their preparation and application in therapyInfo
- Publication number
- BG103937A BG103937A BG103937A BG10393799A BG103937A BG 103937 A BG103937 A BG 103937A BG 103937 A BG103937 A BG 103937A BG 10393799 A BG10393799 A BG 10393799A BG 103937 A BG103937 A BG 103937A
- Authority
- BG
- Bulgaria
- Prior art keywords
- group
- optionally substituted
- therapy
- nitrogen
- naphthalen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The invention is used in therapy and relates to a compound with the general formula in which R1 means alkyl group, V means hydrogen atom, alkyl group with a straight or branching chain, cycloalkyl group, cycloalkylmethyl group, phenyl alkyl group which is optionally substituted in the phenyl ring, carboxymethyl group, alkoxycarbonylmethyl group or carbamoylmethyl group which is optionally substituted at the nitrogen, W means carboxymethyl group, alkoxycarbonylmethyl group, carbamoylmethyl group which is optionally substituted at the nitrogen, 4- to 7-member ring group, optionsally containing oxygen or sulphur atom, pyridylmethyl group, 1-methylpyrolylmnethyl group, furanylmethyl group or 1,3- thiazolylmethyl group or alternatively V and W together with the nitrogen atom with which they are bound form pyrrolidinyl, piperidyl or 1,2,3,4-tetrahydroisoquinolyl group. 6 claims
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9706947A FR2764291B1 (en) | 1997-06-05 | 1997-06-05 | 5-NAPHTALEN-1-YL-1,3-DIOXANE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
FR9706945A FR2764288B1 (en) | 1997-06-05 | 1997-06-05 | 5-NAPHTALEN-1-YL-1,3-DIOXANE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
FR9706944A FR2764287B1 (en) | 1997-06-05 | 1997-06-05 | 5-NAPHTALEN-1-YL-1,3-DIOXANES DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
FR9706946A FR2764289B1 (en) | 1997-06-05 | 1997-06-05 | 5-NAPHTALEN-1-YL-1,3-DIOXANE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
PCT/FR1998/001113 WO1998055474A1 (en) | 1997-06-05 | 1998-06-03 | 5-naphthalen-1-yl-1,3-dioxane derivatives, preparation and therapeutic application |
Publications (1)
Publication Number | Publication Date |
---|---|
BG103937A true BG103937A (en) | 2000-07-31 |
Family
ID=27447000
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG103937A BG103937A (en) | 1997-06-05 | 1999-11-30 | 5-naphthalen-1-yl-1,3-dioxane derivatives, their preparation and application in therapy |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0986552A1 (en) |
JP (1) | JP2002502412A (en) |
KR (1) | KR20010013435A (en) |
CN (1) | CN1265658A (en) |
AR (1) | AR012908A1 (en) |
AU (1) | AU8025198A (en) |
BG (1) | BG103937A (en) |
BR (1) | BR9810742A (en) |
CA (1) | CA2290695A1 (en) |
CO (1) | CO4940480A1 (en) |
EE (1) | EE9900560A (en) |
HU (1) | HUP0002166A3 (en) |
IL (1) | IL133242A0 (en) |
NO (1) | NO995966L (en) |
PL (1) | PL337234A1 (en) |
SK (1) | SK166199A3 (en) |
TR (1) | TR199903022T2 (en) |
WO (1) | WO1998055474A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ2003445A3 (en) * | 2000-07-21 | 2004-08-18 | Ortho@Mcneilápharmaceuticalźáinc | Carbamate compounds intended for prevention or treatment of neuropathic pain and pain associated with histamine a migraine headache |
FR2843964B1 (en) | 2002-08-29 | 2004-10-01 | Sanofi Synthelabo | DIOXANE-2-ALKYLCARBAMATES DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE111460T1 (en) * | 1990-06-15 | 1994-09-15 | Synthelabo | 2-(AMINOALKYL)-5-(ARYLALKYL)1,3-DIOXANE DERIVATIVES, THEIR PRODUCTION AND APPLICATIONS IN THERAPEUTICS. |
FR2714055B1 (en) * | 1993-12-22 | 1996-01-19 | Synthelabo | Derivatives of 5- (arylalkyl) -1,3-dioxane substituted in position 2, their preparation and their use in therapy. |
FR2742152B1 (en) * | 1995-12-06 | 1998-01-16 | Synthelabo | 5-NAPHTALEN-1-YL-1,3-DIOXANES DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
-
1998
- 1998-06-03 CA CA002290695A patent/CA2290695A1/en not_active Abandoned
- 1998-06-03 JP JP50172399A patent/JP2002502412A/en active Pending
- 1998-06-03 PL PL98337234A patent/PL337234A1/en unknown
- 1998-06-03 AU AU80251/98A patent/AU8025198A/en not_active Abandoned
- 1998-06-03 CN CN98807817A patent/CN1265658A/en active Pending
- 1998-06-03 EE EEP199900560A patent/EE9900560A/en unknown
- 1998-06-03 WO PCT/FR1998/001113 patent/WO1998055474A1/en not_active Application Discontinuation
- 1998-06-03 HU HU0002166A patent/HUP0002166A3/en unknown
- 1998-06-03 TR TR1999/03022T patent/TR199903022T2/en unknown
- 1998-06-03 EP EP98928419A patent/EP0986552A1/en not_active Withdrawn
- 1998-06-03 IL IL13324298A patent/IL133242A0/en unknown
- 1998-06-03 AR ARP980102585A patent/AR012908A1/en unknown
- 1998-06-03 SK SK1661-99A patent/SK166199A3/en unknown
- 1998-06-03 BR BR9810742-9A patent/BR9810742A/en not_active IP Right Cessation
- 1998-06-03 KR KR1019997011436A patent/KR20010013435A/en not_active Application Discontinuation
- 1998-06-04 CO CO98031750A patent/CO4940480A1/en unknown
-
1999
- 1999-11-30 BG BG103937A patent/BG103937A/en unknown
- 1999-12-03 NO NO995966A patent/NO995966L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2290695A1 (en) | 1998-12-10 |
BR9810742A (en) | 2000-09-12 |
NO995966D0 (en) | 1999-12-03 |
SK166199A3 (en) | 2000-06-12 |
PL337234A1 (en) | 2000-08-14 |
EE9900560A (en) | 2000-06-15 |
WO1998055474A1 (en) | 1998-12-10 |
JP2002502412A (en) | 2002-01-22 |
AU8025198A (en) | 1998-12-21 |
HUP0002166A3 (en) | 2002-12-28 |
EP0986552A1 (en) | 2000-03-22 |
NO995966L (en) | 2000-02-04 |
CN1265658A (en) | 2000-09-06 |
KR20010013435A (en) | 2001-02-26 |
CO4940480A1 (en) | 2000-07-24 |
IL133242A0 (en) | 2001-03-19 |
TR199903022T2 (en) | 2000-04-21 |
AR012908A1 (en) | 2000-11-22 |
HUP0002166A2 (en) | 2001-06-28 |
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