BE905783A - PROCESS FOR THE PREPARATION OF ANTIBIOTICS OF THE CEPHALOSPORIN TYPE AND INTERMEDIATES FOR THEIR PREPARATION. - Google Patents

PROCESS FOR THE PREPARATION OF ANTIBIOTICS OF THE CEPHALOSPORIN TYPE AND INTERMEDIATES FOR THEIR PREPARATION.

Info

Publication number
BE905783A
BE905783A BE0/217434A BE217434A BE905783A BE 905783 A BE905783 A BE 905783A BE 0/217434 A BE0/217434 A BE 0/217434A BE 217434 A BE217434 A BE 217434A BE 905783 A BE905783 A BE 905783A
Authority
BE
Belgium
Prior art keywords
preparation
antibiotics
intermediates
cephalosporin type
thioesters
Prior art date
Application number
BE0/217434A
Other languages
French (fr)
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Publication of BE905783A publication Critical patent/BE905783A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procédé de préparation de dérivés connus de la céphalosporine. Ce procédé comprend la réaction de dérivés de l'acide 7-amino-céphalosporanique avec des thioesters de l'acide acétique. L'invention comprend également ces thioesters et leur préparation. Deux composés spécialement intéressants pour la conduite de la réaction sont le 2-thiénylthioacétate de S-2-benzothiazolyle et le 1-(1H)-tétrazolylthioacétate de S-2-benzothiazolyle.Process for the preparation of known cephalosporin derivatives. This process involves the reaction of 7-amino-cephalosporanic acid derivatives with thioesters of acetic acid. The invention also includes these thioesters and their preparation. Two compounds which are of particular interest for carrying out the reaction are S-2-benzothiazolyl 2-thienylthioacetate and S-2-benzothiazolyl 1- (1H) -tetrazolylthioacetate.

BE0/217434A 1985-11-20 1986-11-19 PROCESS FOR THE PREPARATION OF ANTIBIOTICS OF THE CEPHALOSPORIN TYPE AND INTERMEDIATES FOR THEIR PREPARATION. BE905783A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0338185A AT383810B (en) 1985-11-20 1985-11-20 METHOD FOR PRODUCING CEPHALOSPORINE DERIVATIVES

Publications (1)

Publication Number Publication Date
BE905783A true BE905783A (en) 1987-05-19

Family

ID=3549668

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/217434A BE905783A (en) 1985-11-20 1986-11-19 PROCESS FOR THE PREPARATION OF ANTIBIOTICS OF THE CEPHALOSPORIN TYPE AND INTERMEDIATES FOR THEIR PREPARATION.

Country Status (9)

Country Link
JP (1) JPS62135477A (en)
AT (1) AT383810B (en)
BE (1) BE905783A (en)
CH (1) CH671228A5 (en)
DE (1) DE3639410A1 (en)
ES (1) ES2002912A6 (en)
FR (1) FR2590257A1 (en)
GB (1) GB2183232B (en)
IT (1) IT1195841B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE77378T1 (en) * 1986-02-07 1992-07-15 Hoffmann La Roche PROCESS FOR THE PREPARATION OF CARBONIC ACID AMIDES.
AT402928B (en) * 1994-12-23 1997-09-25 Biochemie Gmbh NEW METHOD FOR PRODUCING CEFOTAXIM

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0004570B1 (en) * 1978-03-09 1982-04-14 Asahi Kasei Kogyo Kabushiki Kaisha Thiol esters, process for their preparation, pharmaceutical compositions containing them and a process for preparing cephalosporin compounds using the same
EP0047014B1 (en) * 1980-09-02 1986-01-15 Asahi Kasei Kogyo Kabushiki Kaisha Novel thioesters and process for the preparation of the same
DE3071264D1 (en) * 1980-09-19 1986-01-09 Asahi Chemical Ind Process for preparing cephalosporin compounds
US4327211A (en) * 1980-11-26 1982-04-27 Asahi Kasei Kogyo Kabushiki Kaisha Method for preparation of cephalosporin compounds
WO1985004659A1 (en) * 1984-04-10 1985-10-24 Biochemie Gesellschaft M.B.H. Intermediary products of cephalosporine, preparation process thereof and utilization thereof

Also Published As

Publication number Publication date
ATA338185A (en) 1987-01-15
GB2183232A (en) 1987-06-03
IT8667857A0 (en) 1986-11-18
GB2183232B (en) 1989-11-15
GB8627404D0 (en) 1986-12-17
AT383810B (en) 1987-08-25
DE3639410A1 (en) 1987-05-21
IT1195841B (en) 1988-10-27
ES2002912A6 (en) 1988-10-01
CH671228A5 (en) 1989-08-15
FR2590257A1 (en) 1987-05-22
JPS62135477A (en) 1987-06-18

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BIOCHEMIE G.M.B.H.

Effective date: 19901130