BE904149Q - 1,2,4-N-SUBSTITUTED TRIAZOLES, THEIR PREPARATION AND THEIR USE. - Google Patents

1,2,4-N-SUBSTITUTED TRIAZOLES, THEIR PREPARATION AND THEIR USE.

Info

Publication number
BE904149Q
BE904149Q BE0/216210A BE216210A BE904149Q BE 904149 Q BE904149 Q BE 904149Q BE 0/216210 A BE0/216210 A BE 0/216210A BE 216210 A BE216210 A BE 216210A BE 904149 Q BE904149 Q BE 904149Q
Authority
BE
Belgium
Prior art keywords
preparation
substituted triazoles
carboxamides
triazole
alpha
Prior art date
Application number
BE0/216210A
Other languages
French (fr)
Inventor
J T Witkowski
Robins
Original Assignee
Vira Tek Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/452,213 external-priority patent/US3991078A/en
Application filed by Vira Tek Inc filed Critical Vira Tek Inc
Application granted granted Critical
Publication of BE904149Q publication Critical patent/BE904149Q/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056Triazole or tetrazole radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

On prépare des carboxamides, thiocarboxamides, carboxamidines de 1-(G)-1,2,4-triazole antiviraux, de formule I dans lesquels G représente un fragment hydrocarburé labile dans les acides, par exemple un groupe 1-(alpha-alcoxyalkyle), par exemple par la réaction d'addition catalysée par un acide d'un 1,2,4-triazole substitué de façon appropriée d'un éther alpha-beta-insaturé.Carboxamides, thiocarboxamides, 1- (G) -1,2,4-triazole antiviral carboxamides of formula I are prepared, in which G represents an acid labile hydrocarbon moiety, for example a 1- (alpha-alkoxyalkyl) group , for example by the acid-catalyzed addition reaction of an appropriately substituted 1,2,4-triazole of an alpha-beta-unsaturated ether.

BE0/216210A 1974-03-18 1986-01-31 1,2,4-N-SUBSTITUTED TRIAZOLES, THEIR PREPARATION AND THEIR USE. BE904149Q (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/452,213 US3991078A (en) 1971-06-01 1974-03-18 N-substituted 1,2,4-triazoles

Publications (1)

Publication Number Publication Date
BE904149Q true BE904149Q (en) 1986-05-15

Family

ID=23795554

Family Applications (2)

Application Number Title Priority Date Filing Date
BE154412A BE826777R (en) 1974-03-18 1975-03-17 1,2,4, -TRIAZOLE-3-CARBOXAMIDES AS ANTIVIRAL AGENT
BE0/216210A BE904149Q (en) 1974-03-18 1986-01-31 1,2,4-N-SUBSTITUTED TRIAZOLES, THEIR PREPARATION AND THEIR USE.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BE154412A BE826777R (en) 1974-03-18 1975-03-17 1,2,4, -TRIAZOLE-3-CARBOXAMIDES AS ANTIVIRAL AGENT

Country Status (13)

Country Link
JP (2) JPS50154252A (en)
AR (1) AR207138A1 (en)
BE (2) BE826777R (en)
CA (1) CA1050028A (en)
DE (1) DE2511829A1 (en)
DK (1) DK154343C (en)
ES (1) ES435690A2 (en)
FR (1) FR2264533B2 (en)
GB (1) GB1490272A (en)
NL (1) NL7503209A (en)
SE (1) SE7502994L (en)
YU (1) YU42138B (en)
ZA (1) ZA751663B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02106421U (en) * 1989-02-07 1990-08-23
RU2624018C2 (en) * 2016-09-26 2017-06-30 Федеральное государственное бюджетное учреждение науки Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова РАН (ИБХ РАН) 5-(tetrahydrofuran-2-yl)-1,2,4-triazole-3-carboxylic acid amide with antiviral activity, and method for production

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3798209A (en) * 1971-06-01 1974-03-19 Icn Pharmaceuticals 1,2,4-triazole nucleosides

Also Published As

Publication number Publication date
ES435690A2 (en) 1977-02-01
YU65875A (en) 1983-01-21
GB1490272A (en) 1977-10-26
AU7914475A (en) 1976-09-23
NL7503209A (en) 1975-09-22
JPS6133822B2 (en) 1986-08-04
CA1050028A (en) 1979-03-06
DE2511829C2 (en) 1989-06-22
DE2511829A1 (en) 1975-09-25
BE826777R (en) 1975-07-16
DK106475A (en) 1975-09-19
FR2264533B2 (en) 1978-09-01
YU42138B (en) 1988-06-30
FR2264533A2 (en) 1975-10-17
DK154343C (en) 1989-05-22
DK154343B (en) 1988-11-07
JPS50154252A (en) 1975-12-12
ZA751663B (en) 1976-02-25
SE7502994L (en) 1975-09-19
JPS59144773A (en) 1984-08-18
AR207138A1 (en) 1976-09-15

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: VIRATEK INC.

Effective date: 19950131