BE903095A - ANTHRACYCLINE GLYCOSIDES, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME. - Google Patents

ANTHRACYCLINE GLYCOSIDES, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME.

Info

Publication number
BE903095A
BE903095A BE0/215487A BE215487A BE903095A BE 903095 A BE903095 A BE 903095A BE 0/215487 A BE0/215487 A BE 0/215487A BE 215487 A BE215487 A BE 215487A BE 903095 A BE903095 A BE 903095A
Authority
BE
Belgium
Prior art keywords
same
preparing
pharmaceutical composition
composition containing
anthracycline glycosides
Prior art date
Application number
BE0/215487A
Other languages
French (fr)
Inventor
F Angelucci
G Barchielli
M Gigli
S Penco
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of BE903095A publication Critical patent/BE903095A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Ces glycosides d'antracycline répondent à la formule générale I dans laquelle R=H ou OH, X = H ou COCF3; ils sont préparés par condensation de 1-hydroxy-4-déméthoxy-11-désoxy-daunomycinone avec un dérivé protégé de daunosamine; ils ont des propriétés antitumorales quand ils sont employés seuls ou dans des compositions pharmaceutiques.These anthracycline glycosides correspond to the general formula I in which R = H or OH, X = H or COCF3; they are prepared by condensation of 1-hydroxy-4-demethoxy-11-deoxy-daunomycinone with a protected derivative of daunosamine; they have anti-tumor properties when used alone or in pharmaceutical compositions.

BE0/215487A 1984-08-24 1985-08-21 ANTHRACYCLINE GLYCOSIDES, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME. BE903095A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848421491A GB8421491D0 (en) 1984-08-24 1984-08-24 Anthracycline glycosides

Publications (1)

Publication Number Publication Date
BE903095A true BE903095A (en) 1985-12-16

Family

ID=10565768

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/215487A BE903095A (en) 1984-08-24 1985-08-21 ANTHRACYCLINE GLYCOSIDES, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME.

Country Status (8)

Country Link
JP (1) JPS61106590A (en)
BE (1) BE903095A (en)
DE (1) DE3529794A1 (en)
FR (1) FR2569405A1 (en)
GB (2) GB8421491D0 (en)
IT (1) IT1214492B (en)
NL (1) NL8502303A (en)
SE (1) SE8503877L (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5543012A (en) * 1978-09-20 1980-03-26 Sanraku Inc Novel anthracycline derivatine and its preparation
IT1210476B (en) * 1981-05-28 1989-09-14 Erba Farmitalia ANTHRACYCLINES.
FR2551057B1 (en) * 1983-08-30 1986-07-18 Hoechst Lab NOVEL AGLYCONES USEFUL FOR THE PREPARATION OF ANTIBIOTICS AND ANTITUMOR OF THE ANTHRACYCLINE SERIES AND METHODS OF PREPARING THE SAME

Also Published As

Publication number Publication date
GB2164335A (en) 1986-03-19
GB8520835D0 (en) 1985-09-25
IT1214492B (en) 1990-01-18
NL8502303A (en) 1986-03-17
GB8421491D0 (en) 1984-09-26
SE8503877D0 (en) 1985-08-19
JPS61106590A (en) 1986-05-24
DE3529794A1 (en) 1986-03-06
FR2569405A1 (en) 1986-02-28
SE8503877L (en) 1986-02-25
IT8521965A0 (en) 1985-08-22

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