BE902944A - Nouveaux derives de l'acide 4-oxo 2-butenoique renfermant un noyau furyle leur procede de preparation leur application comme medicaments et les compositions les renfermant. - Google Patents

Nouveaux derives de l'acide 4-oxo 2-butenoique renfermant un noyau furyle leur procede de preparation leur application comme medicaments et les compositions les renfermant.

Info

Publication number
BE902944A
BE902944A BE0/215386A BE902944A BE902944A BE 902944 A BE902944 A BE 902944A BE 0/215386 A BE0/215386 A BE 0/215386A BE 902944 A BE902944 A BE 902944A BE 902944 A BE902944 A BE 902944A
Authority
BE
Belgium
Prior art keywords
furyl
medicaments
oxo
preparing
core
Prior art date
Application number
BE0/215386A
Other languages
English (en)
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT19249/83A external-priority patent/IT1193615B/it
Priority claimed from IT22647/83A external-priority patent/IT1169782B/it
Priority claimed from IT21988/84A external-priority patent/IT1179503B/it
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of BE902944A publication Critical patent/BE902944A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Les composés répondant à la formule générale (I) où R est un radical de formule II, III, IV et R' est un hydrogène ou un alcoyle linéaire, ramifié ou cyclisé saturé ou insaturé, renfermant jusqu'à 18 atomes de carbone ainsi que les sels alcalins, alcalino-terreux ou d'amines des composés de formule I dans lesquels R' est un hydrogène. L'invention a également pour objet la préparation desdits produits. Les produits de formule I manifestent une importante activité antiulcéreuse; mis en contact avec la muqueuse gastrique, ils manifestent une activité anti-secrétoire gastrique et cytoprotectrice.
BE0/215386A 1983-01-24 1985-07-19 Nouveaux derives de l'acide 4-oxo 2-butenoique renfermant un noyau furyle leur procede de preparation leur application comme medicaments et les compositions les renfermant. BE902944A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT19249/83A IT1193615B (it) 1983-01-24 1983-01-24 Derivati dell'acido acrilico che comprendono un eterociclo contenente ossigeno quali medicinali,prodotti industriali e procedimento di preparazione
IT22647/83A IT1169782B (it) 1983-08-25 1983-08-25 Derivati dell'acido acrilico che contengono un ciclo ossazolico oppure isossazolico, loro procedimento di preparazione e loro applicazione come farmaco
IT21988/84A IT1179503B (it) 1984-07-20 1984-07-20 Derivati dell'acido 4-osso 2-butenoico che contengono un nucleo furile, loro procedimento di preparazione e loro impiego come medicinali

Publications (1)

Publication Number Publication Date
BE902944A true BE902944A (fr) 1986-01-20

Family

ID=27272946

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/215386A BE902944A (fr) 1983-01-24 1985-07-19 Nouveaux derives de l'acide 4-oxo 2-butenoique renfermant un noyau furyle leur procede de preparation leur application comme medicaments et les compositions les renfermant.

Country Status (2)

Country Link
BE (1) BE902944A (fr)
FR (1) FR2567883B2 (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2481118A1 (fr) * 1980-04-24 1981-10-30 Roussel Uclaf Application a titre de medicaments de derives substitues de l'acide phenyl-4-oxo-2-butenoique

Also Published As

Publication number Publication date
FR2567883A2 (fr) 1986-01-24
FR2567883B2 (fr) 1987-03-06

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ROUSSEL-UCLAF

Effective date: 19930731