BE902911A - N-IMIDAZOLYL DERIVATIVES AND THEIR PREPARATION - Google Patents

N-IMIDAZOLYL DERIVATIVES AND THEIR PREPARATION

Info

Publication number
BE902911A
BE902911A BE0/215362A BE215362A BE902911A BE 902911 A BE902911 A BE 902911A BE 0/215362 A BE0/215362 A BE 0/215362A BE 215362 A BE215362 A BE 215362A BE 902911 A BE902911 A BE 902911A
Authority
BE
Belgium
Prior art keywords
radical
preparation
compounds
symbols
hydrogen atom
Prior art date
Application number
BE0/215362A
Other languages
French (fr)
Inventor
P Cozzi
G Carganico
U Branzoli
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of BE902911A publication Critical patent/BE902911A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Des composés de la formule (I) dans laquelle chacun des symboles R1, R2, R3 et R4 qui peuvent avoir des significations identiques ou différentes, représente un atome d'hydrogène; un atome d'halogène; un radical hydroxyle; un radical cyano, un radical alkyle en C1-C6; un radical alcoxy en C1-C6; un radical acyle en C2-C4 ou un radical acylamino en C2-C4; un radical -SR', -NR'R'', -CH2OR', -CONR'R'', -CH2NR'R'', -PO(OR')2, -CH2COOR', -CH2CONR'R où chacun des symboles R' et R'', qui peuvent avoir des significations identiques ou différentes, représente un atome d'hydrogène ou un radical alkyle en C1-C6, ainsi que les sels pharmaceutiquement acceptables de ces composés. Utilisation pour le traitement des migraines.Compounds of formula (I) in which each of the symbols R1, R2, R3 and R4 which may have the same or different meanings, represents a hydrogen atom; a halogen atom; a hydroxyl radical; a cyano radical, a C1-C6 alkyl radical; a C1-C6 alkoxy radical; a C2-C4 acyl radical or a C2-C4 acylamino radical; a radical -SR ', -NR'R' ', -CH2OR', -CONR'R '', -CH2NR'R '', -PO (OR ') 2, -CH2COOR', -CH2CONR'R where each of symbols R 'and R' ', which may have the same or different meanings, represents a hydrogen atom or a C1-C6 alkyl radical, as well as the pharmaceutically acceptable salts of these compounds. Use for the treatment of migraines.

BE0/215362A 1984-07-17 1985-07-16 N-IMIDAZOLYL DERIVATIVES AND THEIR PREPARATION BE902911A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08418220A GB2161801B (en) 1984-07-17 1984-07-17 N-imidazolyl derivatives and process for their preparation

Publications (1)

Publication Number Publication Date
BE902911A true BE902911A (en) 1986-01-16

Family

ID=10564020

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/215362A BE902911A (en) 1984-07-17 1985-07-16 N-IMIDAZOLYL DERIVATIVES AND THEIR PREPARATION

Country Status (4)

Country Link
JP (1) JPS6140282A (en)
BE (1) BE902911A (en)
DE (1) DE3519432A1 (en)
GB (1) GB2161801B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6984627B1 (en) 1993-06-03 2006-01-10 Astrazeneca Ab Peptide derivatives
SE0001803D0 (en) 2000-05-16 2000-05-16 Astrazeneca Ab New compounds i

Also Published As

Publication number Publication date
DE3519432A1 (en) 1986-01-23
JPS6140282A (en) 1986-02-26
GB8418220D0 (en) 1984-08-22
GB2161801A (en) 1986-01-22
GB2161801B (en) 1987-10-07

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A.

Effective date: 19900731