BE899940A - N-IMIDAZOLYL DERIVATIVES OF BICYCLIC COMPOUNDS AND METHODS FOR PREPARING THE SAME. - Google Patents

N-IMIDAZOLYL DERIVATIVES OF BICYCLIC COMPOUNDS AND METHODS FOR PREPARING THE SAME.

Info

Publication number
BE899940A
BE899940A BE0/213161A BE213161A BE899940A BE 899940 A BE899940 A BE 899940A BE 0/213161 A BE0/213161 A BE 0/213161A BE 213161 A BE213161 A BE 213161A BE 899940 A BE899940 A BE 899940A
Authority
BE
Belgium
Prior art keywords
preparing
methods
same
compounds
bicyclic compounds
Prior art date
Application number
BE0/213161A
Other languages
French (fr)
Inventor
P Cozzi
G Carganico
A Pillan
U Branzoli
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of BE899940A publication Critical patent/BE899940A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Abstract

L'invention a plus particulièrement pour objet des dérivés N-imidazolyliques de composés bicycliques, plus particulièrement des dérivés du 3,4-dihydro-2H-1-benzopyrane, du 2H-1-benzopyrane, du 1,2,3,4,tétrahydronaphtalène, du 1,2-dihydronaphtalène, du naphtalène, de l'indane et de l'indène, ainsi qu'un procédé de préparation de ces composés et les compositions pharmaceutiques qui les contiennent. Les composés en question conviennent au traitement de troubles circulatoires, de la microangiopathie diabétique, à titre d'agents anti-hypertension, pour le traitement de l'angine de poitrine, etc.A more particular subject of the invention is N-imidazolyl derivatives of bicyclic compounds, more particularly derivatives of 3,4-dihydro-2H-1-benzopyran, of 2H-1-benzopyrane, of 1,2,3,4, tetrahydronaphthalene, 1,2-dihydronaphthalene, naphthalene, indane and indene, as well as a process for the preparation of these compounds and the pharmaceutical compositions containing them. The compounds in question are suitable for the treatment of circulatory disorders, diabetic microangiopathy, as anti-hypertension agents, for the treatment of angina pectoris, etc.

BE0/213161A 1983-06-20 1984-06-18 N-IMIDAZOLYL DERIVATIVES OF BICYCLIC COMPOUNDS AND METHODS FOR PREPARING THE SAME. BE899940A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838316744A GB8316744D0 (en) 1983-06-20 1983-06-20 N-imidazolyl derivatives of bicyclic compounds

Publications (1)

Publication Number Publication Date
BE899940A true BE899940A (en) 1984-12-18

Family

ID=10544506

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/213161A BE899940A (en) 1983-06-20 1984-06-18 N-IMIDAZOLYL DERIVATIVES OF BICYCLIC COMPOUNDS AND METHODS FOR PREPARING THE SAME.

Country Status (4)

Country Link
JP (1) JPS6016975A (en)
BE (1) BE899940A (en)
DE (1) DE3420592A1 (en)
GB (1) GB8316744D0 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2644593B2 (en) * 1989-09-14 1997-08-25 キヤノン株式会社 Elastic rotating body and fixing device
GB9102862D0 (en) * 1991-02-11 1991-03-27 Erba Carlo Spa N-imidazolyl derivatives of substituted or alkoxymino tetrahydronaphthalenes and chromans
US9271963B2 (en) 2005-03-03 2016-03-01 Universitat Des Saarlandes Selective inhibitors of human corticosteroid synthases

Also Published As

Publication number Publication date
JPS6016975A (en) 1985-01-28
DE3420592A1 (en) 1984-12-20
GB8316744D0 (en) 1983-07-20

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.R.L.

Effective date: 19920630