BE878170A - NEW THIOPHENECARBOXAMIDOALKYLMERCAPTANS USEFUL IN PARTICULAR AS MUCOLYTICS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

NEW THIOPHENECARBOXAMIDOALKYLMERCAPTANS USEFUL IN PARTICULAR AS MUCOLYTICS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
BE878170A
BE878170A BE0/196672A BE196672A BE878170A BE 878170 A BE878170 A BE 878170A BE 0/196672 A BE0/196672 A BE 0/196672A BE 196672 A BE196672 A BE 196672A BE 878170 A BE878170 A BE 878170A
Authority
BE
Belgium
Prior art keywords
thiophenecarboxamidoalkylmercaptans
mucolytics
new
useful
pharmaceutical compositions
Prior art date
Application number
BE0/196672A
Other languages
French (fr)
Inventor
H Munson
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of BE878170A publication Critical patent/BE878170A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants

Description

       

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L'inventions également pour objet de nouvelles compo-

  
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du meilleur =de de mise en oeuvre de l'invention. 

  
Dans la définition des symboles et dans la formule (I)

  
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On peut préparer les mercaptans selon l'invention

  
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La préparation des esters intermédiaires obtenus 

  
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diluant et support solide acceptable en pharmacie pour la poudre  micronisée, on peut citer l'acide lactique. 

  
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Inventions also for the purpose of new composi-

  
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of the best = of implementation of the invention.

  
In the definition of symbols and in formula (I)

  
 <EMI ID = 9.1>

  

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The mercaptans according to the invention can be prepared

  
 <EMI ID = 11.1> <EMI ID = 12.1>
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The preparation of the intermediate esters obtained

  
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diluent and solid support which is acceptable in pharmacies for the micronized powder, mention may be made of lactic acid.

  
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Claims (1)

<EMI ID=36.1> <EMI ID = 36.1>
BE0/196672A 1978-08-10 1979-08-09 NEW THIOPHENECARBOXAMIDOALKYLMERCAPTANS USEFUL IN PARTICULAR AS MUCOLYTICS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BE878170A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93274678A 1978-08-10 1978-08-10

Publications (1)

Publication Number Publication Date
BE878170A true BE878170A (en) 1979-12-03

Family

ID=25462843

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/196672A BE878170A (en) 1978-08-10 1979-08-09 NEW THIOPHENECARBOXAMIDOALKYLMERCAPTANS USEFUL IN PARTICULAR AS MUCOLYTICS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (3)

Country Link
JP (1) JPS5531076A (en)
BE (1) BE878170A (en)
ZA (1) ZA793738B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0439772Y2 (en) * 1988-06-20 1992-09-17

Also Published As

Publication number Publication date
JPS6361311B2 (en) 1988-11-28
JPS5531076A (en) 1980-03-05
ZA793738B (en) 1980-10-29

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: A.H. ROBINS CY INC.

Effective date: 19910831